urea has been researched along with Cardiomegaly in 22 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " R712 is adjacent to the binding site of the heart failure drug omecamtiv mecarbil (OM)." | 4.02 | Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil. ( Atherton, JL; Barua, B; Forgacs, E; Goldman, YE; Ostap, EM; Shuman, H; Snoberger, A; Winkelmann, DA, 2021) |
| "Symptoms due to orthostatic and exertional hypotension occurred in 23-4 per cent of 448 hypertensive patients treated with guanethidine, debrisoquine, or bethanidine." | 3.65 | Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure. ( Smith, AJ; Talbot, S, 1975) |
| "In time, HIP rats developed cardiac hypertrophy and left-ventricular dilation." | 1.40 | Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. ( Chiamvimonvat, N; Despa, F; Despa, S; Dong, H; Hammock, BD; Harris, TR; Li, N; Margulies, KB; Sharma, S; Taegtmeyer, H, 2014) |
| "2." | 1.36 | Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats. ( Bai, CF; Cao, W; Guo, HJ; Liu, JC; Liu, SB; Yang, Q; Yi, DH; Zhang, XN; Zhao, MG; Zhao, R, 2010) |
| "Both types of cardiac hypertrophy were associated with a decreased coronary vascular resistance." | 1.25 | Myocardial transcapillary exchange in the hypertrophied heart of the dog. ( Diana, JN; Laughlin, MH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kuma, A | 1 |
| Wang, XH | 1 |
| Klein, JD | 1 |
| Tan, L | 1 |
| Naqvi, N | 1 |
| Rianto, F | 1 |
| Huang, Y | 1 |
| Yu, M | 1 |
| Sands, JM | 1 |
| Snoberger, A | 1 |
| Barua, B | 1 |
| Atherton, JL | 1 |
| Shuman, H | 1 |
| Forgacs, E | 1 |
| Goldman, YE | 1 |
| Winkelmann, DA | 1 |
| Ostap, EM | 1 |
| Despa, S | 1 |
| Sharma, S | 1 |
| Harris, TR | 1 |
| Dong, H | 1 |
| Li, N | 1 |
| Chiamvimonvat, N | 1 |
| Taegtmeyer, H | 1 |
| Margulies, KB | 1 |
| Hammock, BD | 1 |
| Despa, F | 1 |
| Gross, GJ | 1 |
| Nithipatikom, K | 1 |
| Bai, CF | 1 |
| Liu, JC | 1 |
| Zhao, R | 1 |
| Cao, W | 1 |
| Liu, SB | 1 |
| Zhang, XN | 1 |
| Guo, HJ | 1 |
| Yang, Q | 1 |
| Yi, DH | 1 |
| Zhao, MG | 1 |
| Kuro, T | 1 |
| Okahara, A | 1 |
| Nose, M | 1 |
| Ikuse, T | 1 |
| Matsumura, Y | 1 |
| McMahon, AC | 1 |
| Greenwald, SE | 1 |
| Dodd, SM | 1 |
| Hurst, MJ | 1 |
| Raine, AE | 1 |
| Talbot, S | 1 |
| Smith, AJ | 1 |
| Laughlin, MH | 1 |
| Diana, JN | 1 |
| Oganesian, SS | 1 |
| Koshkarian, AO | 1 |
| Eloian, MA | 1 |
| Zaminian, TS | 1 |
| Hüting, J | 1 |
| Wizemann, V | 1 |
| Kramer, W | 1 |
| Bechthold, A | 1 |
| Thormann, J | 1 |
| Beevers, DG | 1 |
| Fairman, MJ | 1 |
| Hamilton, M | 1 |
| Harpur, JE | 1 |
| Jackson, WB | 1 |
| Wilcken, DE | 1 |
| Lvoff, R | 1 |
| Kato, T | 1 |
| Goss, LZ | 1 |
| Rosa, RM | 1 |
| O'Brien, WM | 1 |
| Ayers, CR | 1 |
| Wood, JE | 1 |
| Bottomley, JP | 1 |
| Bradley, J | 1 |
| Whitehouse, GH | 1 |
| Pincherle, G | 1 |
| Robinson, D | 1 |
| Hopkins, BE | 1 |
| Lloyd, BL | 1 |
| Taylor, RR | 1 |
| Cantin, M | 1 |
| Forthomme, D | 1 |
| Bajusz, E | 1 |
3 reviews available for urea and Cardiomegaly
| Article | Year |
|---|---|
Soluble epoxide hydrolase: a new target for cardioprotection.
Topics: Adamantane; Animals; Cardiomegaly; Cardiotonic Agents; Coronary Disease; Dose-Response Relationship, | 2009 |
Idiopathic myocardiopathy in Ceylon.
Topics: Blood Protein Electrophoresis; Body Weight; Cardiomegaly; Cardiomyopathies; Cholesterol; Diet; Femal | 1969 |
Renal glomerulus in experimental congestive heart failure: ultrastructural and functional study.
Topics: Animals; Blood Glucose; Blood Pressure; Blood Proteins; Cardiomegaly; Cardiomyopathies; Cholesterol; | 1973 |
19 other studies available for urea and Cardiomegaly
| Article | Year |
|---|---|
Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease.
Topics: Actins; Animals; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Ventricles; Hypertension; Kidney; M | 2020 |
Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil.
Topics: Cardiomegaly; Cardiotonic Agents; Heart Failure; Humans; Mutation; Urea; Ventricular Myosins | 2021 |
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.
Topics: Adamantane; Animals; Animals, Genetically Modified; Calcium; Cardiomegaly; Diabetes Mellitus, Type 2 | 2014 |
Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calcium Channels, L-Type; Cardiomegaly; Cardiomyopat | 2010 |
Effects of SA7060, a novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, on deoxycorticosterone acetate-salt-induced hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; | 2000 |
Prolonged calcium transients and myocardial remodelling in early experimental uraemia.
Topics: Animals; Blood Pressure; Calcium; Cardiomegaly; Creatinine; Disease Models, Animal; Glomerular Filtr | 2002 |
Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure.
Topics: Bethanidine; Cardiomegaly; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guanidines; Heart Ra | 1975 |
Myocardial transcapillary exchange in the hypertrophied heart of the dog.
Topics: Animals; Capillaries; Cardiomegaly; Coronary Circulation; Dogs; Female; Hemodynamics; Inulin; Male; | 1975 |
[1 of the molecular factors of development of compensatory myocardial hypertrophy].
Topics: Actins; Animals; Cardiomegaly; Culture Media; Dogs; Electrophoresis, Polyacrylamide Gel; In Vitro Te | 1977 |
Course of left ventricular hypertrophy and function in end-stage renal disease after renal transplantation.
Topics: Arteriovenous Shunt, Surgical; Body Surface Area; Body Weight; Cardiomegaly; Creatinine; Echocardiog | 1992 |
Acute effects of dialysis on myocardial contractility: influence of cardiac status and calcium/potassium ratio.
Topics: Adult; Blood Pressure; Calcium; Cardiac Output; Cardiomegaly; Heart Function Tests; Heart Rate; Huma | 1986 |
Antihypertensive treatment and the course of established cerebral vascular disease.
Topics: Angina Pectoris; Antihypertensive Agents; Cardiomegaly; Cerebrovascular Disorders; Diuretics; Female | 1973 |
Tolerance and side effects during long term treatment of hypertension with debrisoquine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Cardiomegaly; Debrisoquin; Drug T | 1972 |
Glucagon in resistant heart-failure and cardiogenic shock.
Topics: Adult; Bundle-Branch Block; Cardiac Glycosides; Cardiac Output; Cardiomegaly; Diuretics; Electrolyte | 1970 |
Myocardial amide-nitrogen metabolism with special reference to ammonia metabolism.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amides; Amino Acids; Ammonia; Animals; Blood Pressure; | 1968 |
Predicting death from renal failure in primary hypertension.
Topics: Acute Kidney Injury; Age Factors; Blood Pressure; Cardiomegaly; Creatinine; Female; Humans; Hyperten | 1969 |
Waldenstrom's macroglobulinaemia and amyloidosis with subcutaneous calcification and lymphographic appearances.
Topics: Amyloidosis; Biopsy; Bone Marrow Cells; Calcinosis; Calcium; Cardiomegaly; Cyclophosphamide; Hematoc | 1974 |
Mean blood pressure and its relation to other factors determined at a routine executive health examination.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aortic Diseases; Blood Pressure; Blood Pressure Determin | 1974 |
Myocardial digoxin uptake in pressure overload right ventricular hypertrophy.
Topics: Animals; Calcium; Cardiomegaly; Creatinine; Digoxin; Dogs; Electrocardiography; Heart Ventricles; He | 1974 |