urea has been researched along with Cardiac Hypertrophy in 22 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " R712 is adjacent to the binding site of the heart failure drug omecamtiv mecarbil (OM)." | 4.02 | Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil. ( Atherton, JL; Barua, B; Forgacs, E; Goldman, YE; Ostap, EM; Shuman, H; Snoberger, A; Winkelmann, DA, 2021) |
| "Symptoms due to orthostatic and exertional hypotension occurred in 23-4 per cent of 448 hypertensive patients treated with guanethidine, debrisoquine, or bethanidine." | 3.65 | Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure. ( Smith, AJ; Talbot, S, 1975) |
| "In time, HIP rats developed cardiac hypertrophy and left-ventricular dilation." | 1.40 | Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. ( Chiamvimonvat, N; Despa, F; Despa, S; Dong, H; Hammock, BD; Harris, TR; Li, N; Margulies, KB; Sharma, S; Taegtmeyer, H, 2014) |
| "2." | 1.36 | Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats. ( Bai, CF; Cao, W; Guo, HJ; Liu, JC; Liu, SB; Yang, Q; Yi, DH; Zhang, XN; Zhao, MG; Zhao, R, 2010) |
| "Both types of cardiac hypertrophy were associated with a decreased coronary vascular resistance." | 1.25 | Myocardial transcapillary exchange in the hypertrophied heart of the dog. ( Diana, JN; Laughlin, MH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kuma, A | 1 |
| Wang, XH | 1 |
| Klein, JD | 1 |
| Tan, L | 1 |
| Naqvi, N | 1 |
| Rianto, F | 1 |
| Huang, Y | 1 |
| Yu, M | 1 |
| Sands, JM | 1 |
| Snoberger, A | 1 |
| Barua, B | 1 |
| Atherton, JL | 1 |
| Shuman, H | 1 |
| Forgacs, E | 1 |
| Goldman, YE | 1 |
| Winkelmann, DA | 1 |
| Ostap, EM | 1 |
| Despa, S | 1 |
| Sharma, S | 1 |
| Harris, TR | 1 |
| Dong, H | 1 |
| Li, N | 1 |
| Chiamvimonvat, N | 1 |
| Taegtmeyer, H | 1 |
| Margulies, KB | 1 |
| Hammock, BD | 1 |
| Despa, F | 1 |
| Gross, GJ | 1 |
| Nithipatikom, K | 1 |
| Bai, CF | 1 |
| Liu, JC | 1 |
| Zhao, R | 1 |
| Cao, W | 1 |
| Liu, SB | 1 |
| Zhang, XN | 1 |
| Guo, HJ | 1 |
| Yang, Q | 1 |
| Yi, DH | 1 |
| Zhao, MG | 1 |
| Kuro, T | 1 |
| Okahara, A | 1 |
| Nose, M | 1 |
| Ikuse, T | 1 |
| Matsumura, Y | 1 |
| McMahon, AC | 1 |
| Greenwald, SE | 1 |
| Dodd, SM | 1 |
| Hurst, MJ | 1 |
| Raine, AE | 1 |
| Talbot, S | 1 |
| Smith, AJ | 1 |
| Laughlin, MH | 1 |
| Diana, JN | 1 |
| Oganesian, SS | 1 |
| Koshkarian, AO | 1 |
| Eloian, MA | 1 |
| Zaminian, TS | 1 |
| Hüting, J | 1 |
| Wizemann, V | 1 |
| Kramer, W | 1 |
| Bechthold, A | 1 |
| Thormann, J | 1 |
| Beevers, DG | 1 |
| Fairman, MJ | 1 |
| Hamilton, M | 1 |
| Harpur, JE | 1 |
| Jackson, WB | 1 |
| Wilcken, DE | 1 |
| Lvoff, R | 1 |
| Kato, T | 1 |
| Goss, LZ | 1 |
| Rosa, RM | 1 |
| O'Brien, WM | 1 |
| Ayers, CR | 1 |
| Wood, JE | 1 |
| Bottomley, JP | 1 |
| Bradley, J | 1 |
| Whitehouse, GH | 1 |
| Pincherle, G | 1 |
| Robinson, D | 1 |
| Hopkins, BE | 1 |
| Lloyd, BL | 1 |
| Taylor, RR | 1 |
| Cantin, M | 1 |
| Forthomme, D | 1 |
| Bajusz, E | 1 |
3 reviews available for urea and Cardiac Hypertrophy
| Article | Year |
|---|---|
Soluble epoxide hydrolase: a new target for cardioprotection.
Topics: Adamantane; Animals; Cardiomegaly; Cardiotonic Agents; Coronary Disease; Dose-Response Relationship, | 2009 |
Idiopathic myocardiopathy in Ceylon.
Topics: Blood Protein Electrophoresis; Body Weight; Cardiomegaly; Cardiomyopathies; Cholesterol; Diet; Femal | 1969 |
Renal glomerulus in experimental congestive heart failure: ultrastructural and functional study.
Topics: Animals; Blood Glucose; Blood Pressure; Blood Proteins; Cardiomegaly; Cardiomyopathies; Cholesterol; | 1973 |
19 other studies available for urea and Cardiac Hypertrophy
| Article | Year |
|---|---|
Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease.
Topics: Actins; Animals; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Ventricles; Hypertension; Kidney; M | 2020 |
Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil.
Topics: Cardiomegaly; Cardiotonic Agents; Heart Failure; Humans; Mutation; Urea; Ventricular Myosins | 2021 |
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.
Topics: Adamantane; Animals; Animals, Genetically Modified; Calcium; Cardiomegaly; Diabetes Mellitus, Type 2 | 2014 |
Role of 5-HT 2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calcium Channels, L-Type; Cardiomegaly; Cardiomyopat | 2010 |
Effects of SA7060, a novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, on deoxycorticosterone acetate-salt-induced hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; | 2000 |
Prolonged calcium transients and myocardial remodelling in early experimental uraemia.
Topics: Animals; Blood Pressure; Calcium; Cardiomegaly; Creatinine; Disease Models, Animal; Glomerular Filtr | 2002 |
Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure.
Topics: Bethanidine; Cardiomegaly; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guanidines; Heart Ra | 1975 |
Myocardial transcapillary exchange in the hypertrophied heart of the dog.
Topics: Animals; Capillaries; Cardiomegaly; Coronary Circulation; Dogs; Female; Hemodynamics; Inulin; Male; | 1975 |
[1 of the molecular factors of development of compensatory myocardial hypertrophy].
Topics: Actins; Animals; Cardiomegaly; Culture Media; Dogs; Electrophoresis, Polyacrylamide Gel; In Vitro Te | 1977 |
Course of left ventricular hypertrophy and function in end-stage renal disease after renal transplantation.
Topics: Arteriovenous Shunt, Surgical; Body Surface Area; Body Weight; Cardiomegaly; Creatinine; Echocardiog | 1992 |
Acute effects of dialysis on myocardial contractility: influence of cardiac status and calcium/potassium ratio.
Topics: Adult; Blood Pressure; Calcium; Cardiac Output; Cardiomegaly; Heart Function Tests; Heart Rate; Huma | 1986 |
Antihypertensive treatment and the course of established cerebral vascular disease.
Topics: Angina Pectoris; Antihypertensive Agents; Cardiomegaly; Cerebrovascular Disorders; Diuretics; Female | 1973 |
Tolerance and side effects during long term treatment of hypertension with debrisoquine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Cardiomegaly; Debrisoquin; Drug T | 1972 |
Glucagon in resistant heart-failure and cardiogenic shock.
Topics: Adult; Bundle-Branch Block; Cardiac Glycosides; Cardiac Output; Cardiomegaly; Diuretics; Electrolyte | 1970 |
Myocardial amide-nitrogen metabolism with special reference to ammonia metabolism.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amides; Amino Acids; Ammonia; Animals; Blood Pressure; | 1968 |
Predicting death from renal failure in primary hypertension.
Topics: Acute Kidney Injury; Age Factors; Blood Pressure; Cardiomegaly; Creatinine; Female; Humans; Hyperten | 1969 |
Waldenstrom's macroglobulinaemia and amyloidosis with subcutaneous calcification and lymphographic appearances.
Topics: Amyloidosis; Biopsy; Bone Marrow Cells; Calcinosis; Calcium; Cardiomegaly; Cyclophosphamide; Hematoc | 1974 |
Mean blood pressure and its relation to other factors determined at a routine executive health examination.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Aortic Diseases; Blood Pressure; Blood Pressure Determin | 1974 |
Myocardial digoxin uptake in pressure overload right ventricular hypertrophy.
Topics: Animals; Calcium; Cardiomegaly; Creatinine; Digoxin; Dogs; Electrocardiography; Heart Ventricles; He | 1974 |