Compounds > urea
Page last updated: 2024-10-21

urea and Cancer of Skin

urea has been researched along with Cancer of Skin in 38 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
" Here, we present our results on the expression of HMGA1 in murine skin carcinoma as detected by acid-urea electrophoresis, reverse-phase high-performance liquid chromatography and Western blot."3.71Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma. ( Jain, A; Rajeswari, MR; Ray, R; Singh, D, 2001)
"Basal cell carcinoma is a semi-malignant epithelial skin tumour with a locally destructive growth pattern but a very low tendency to metastases."2.43[Non-surgical therapy of basal cell carcinoma of the head-neck region]. ( Dissemond, J; Grabbe, S, 2006)
"Malignant melanoma has an increasing incidence rate and the metastatic disease is notoriously resistant to standard chemotherapy."1.42Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma. ( Emilsen, E; Engesæter, B; Fjær, R; Flørenes, VA; Giller Fleten, K; Magnussen, GI; Nähse-Kumpf, V; Slipicevic, A, 2015)
"Malignant melanoma is the deadliest form of skin cancer, known for its drug resistance and high metastatic potential."1.37Melanoma prevention using topical PBISe. ( Amin, S; Chung, CY; Desai, D; Madhunapantula, SV; Robertson, GP, 2011)
"Malignant melanoma is the most deadly form of skin cancer due to its highly metastatic nature."1.35PBISe, a novel selenium-containing drug for the treatment of malignant melanoma. ( Amin, S; Desai, D; Huh, SJ; Madhunapantula, SV; Robertson, GP; Sharma, A, 2008)
"Peracetic acid was a potent tumor promoter and a weak complete carcinogen on the skin of female ICR Swiss mice."1.25Cocarcinogenic activity of peroxy compounds. ( Bock, FG; Fox, HW; Myers, HK, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199020 (52.63)18.7374
1990's3 (7.89)18.2507
2000's6 (15.79)29.6817
2010's8 (21.05)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Abramova, OB1
Kaplan, MA1
Grin, MA1
Yuzhakov, VV1
Suvorov, NV1
Mironov, AF1
Drozhzhina, VV1
Churikova, TP1
Kozlovtseva, EA1
Bandurko, LN1
Yakovleva, ND1
Ivanov, SA1
Kaprin, AD1
Yefidoff-Freedman, R1
Fan, J1
Yan, L1
Zhang, Q1
Dos Santos, GRR1
Rana, S1
Contreras, JI1
Sahoo, R1
Wan, D1
Young, J1
Dias Teixeira, KL1
Morisseau, C1
Halperin, J1
Hammock, B1
Natarajan, A1
Wang, P1
Chorev, M1
Aktas, BH1
Park, M1
Naidoo, AA1
Burns, A1
Choi, JK1
Gatfield, KM1
Vidgeon-Hart, M1
Bae, IH1
Lee, CS1
Choi, G1
Powell, AJ1
Park, YH1
Fagg, R1
Nieto Rodríguez, D1
Gómez Fernández, C1
Rueda Carnero, JM1
Yao, Y1
Mark, LA1
Madhunapantula, SV3
Sharma, A2
Gowda, R1
Robertson, GP3
Magnussen, GI1
Emilsen, E1
Giller Fleten, K1
Engesæter, B1
Nähse-Kumpf, V1
Fjær, R1
Slipicevic, A1
Flørenes, VA1
Melnikova, VO1
Bar-Eli, M1
Chung, CY1
Desai, D2
Amin, S2
Rovedo, MA1
Krett, NL1
Rosen, ST1
PASSEN, S1
SCHULTZ, RB1
Collet, AM1
Palmieri, M1
Molinari, B1
Schwint, AE1
Itoiz, ME1
Dissemond, J1
Grabbe, S1
Stavanja, MS1
Curtin, GM1
Ayres, PH1
Bombick, ER1
Borgerding, MF1
Morgan, WT1
Garner, CD1
Pence, DH1
Swauger, JE1
Huh, SJ1
Kägi, MK1
Trüeb, R1
Wüthrich, B1
Burg, G1
Mayer, P1
Schmid, H1
Schaber, B1
Fierlbeck, G1
Rajeswari, MR1
Singh, D1
Jain, A1
Ray, R1
Bock, FG1
Myers, HK1
Fox, HW1
Schlagenhauff, B1
Klessen, C1
Teichmann-Dörr, S1
Breuninger, H1
Rassner, G1
Tempest, MN2
Danopoulos, ED3
Danopoulou, IE2
Danopoulos, IE1
Bhattacharaya, M2
Carruthers, C4
Thomas, C1
Bollmann, R1
Kupfer, M1
Kupfer, G1
Zintzsch, I1
Juhls, H1
Ehrentraut, W1
Cohen, SM1
Greenspan, EM1
Weiner, MJ1
Kabakow, B1
Hoffmann, F1
Graffi, A1
Ferry, AP1
Hiraki, S1
Moon, JH1
Leaver, DD1
Swann, PF1
Magee, PN1

Reviews

2 reviews available for urea and Cancer of Skin

ArticleYear
[Non-surgical therapy of basal cell carcinoma of the head-neck region].
    Laryngo- rhino- otologie, 2006, Volume: 85, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplas

2006
From nitrosamines to nitrosoureas and nitrosoquanidines.
    Food and cosmetics toxicology, 1971, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Drinking; Food

1971

Trials

1 trial available for urea and Cancer of Skin

ArticleYear
Triple combination chemotherapy of disseminated melanoma.
    Cancer, 1972, Volume: 29, Issue:6

    Topics: Aged; Alkylating Agents; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Drug Combinati

1972

Other Studies

35 other studies available for urea and Cancer of Skin

ArticleYear
Photodynamic Therapy of Melanoma B16 with Chlorin E6 Conjugated with a PSMA-Ligand.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:4

    Topics: Animals; Cell Line, Tumor; Chlorophyllides; Female; Ligands; Melanoma, Experimental; Mice; Mice, Inb

2021
Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Dr

2017
Do TRPV1 antagonists increase the risk for skin tumourigenesis? A collaborative in vitro and in vivo assessment.
    Cell biology and toxicology, 2018, Volume: 34, Issue:2

    Topics: Acrylamides; Animals; Anthracenes; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cell Line; Ce

2018
Facial spiny follicular hyperkeratosis induced by vemurafenib.
    The Journal of dermatology, 2018, Volume: 45, Issue:2

    Topics: Aged; Antineoplastic Agents; Diagnosis, Differential; Face; Female; Humans; Keratosis; Melanoma; Sal

2018
Woringer-Kolopp disease mimicking foot dermatitis.
    Cutis, 2012, Volume: 90, Issue:6

    Topics: Aged; Anticarcinogenic Agents; Bexarotene; CD3 Complex; Dermatologic Agents; Diagnosis, Differential

2012
Identification of glycogen synthase kinase 3α as a therapeutic target in melanoma.
    Pigment cell & melanoma research, 2013, Volume: 26, Issue:6

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; G1 Phase; Glycogen Synthase Kinase

2013
Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma.
    BMC cancer, 2015, Jun-10, Volume: 15

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Cyc

2015
Searching for the Achilles' heel of melanoma cells: new treatment modalities.
    Pigment cell & melanoma research, 2008, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Clinical Trials as Topic; Enzyme Inhib

2008
Melanoma prevention using topical PBISe.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:6

    Topics: Administration, Topical; Animals; Apoptosis; Cell Cycle; Cell Proliferation; Cells, Cultured; Female

2011
Inhibition of glycogen synthase kinase-3 increases the cytotoxicity of enzastaurin.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:7

    Topics: Antineoplastic Agents; beta Catenin; Cells, Cultured; Glycogen Synthase Kinase 3; Humans; Hyaluronan

2011
USE OF THE SHOPE PAPILLOMA VIRUS-INDUCED ARGINASE AS A BIOCHEMICAL MARKER IN VITRO.
    Virology, 1965, Volume: 26

    Topics: Animals; Arginase; Biological Assay; Biomarkers; Cottontail rabbit papillomavirus; In Vitro Techniqu

1965
Experimental study to test the potential tumor promotion effect of a tooth bleaching agent.
    Acta odontologica latinoamericana : AOL, 2001, Volume: 14, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbamide Peroxide; Carcinogens; Cricetinae; Disease Mode

2001
Safety assessment of diammonium phosphate and urea used in the manufacture of cigarettes.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 59, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; CHO Cells; Cocarcinogenesis; Co

2008
PBISe, a novel selenium-containing drug for the treatment of malignant melanoma.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Prolifer

2008
Confluent and reticulated papillomatosis associated with atopy. Successful treatment with topical urea and tretinoin.
    The British journal of dermatology, 1996, Volume: 134, Issue:2

    Topics: Adolescent; Adult; Female; Humans; Hypersensitivity, Immediate; Male; Papilloma; Skin Neoplasms; Tre

1996
Tumor-associated cysteine proteinase activities in human melanoma cells and fibroblasts of different origin.
    European journal of cell biology, 1997, Volume: 73, Issue:4

    Topics: Cell Line; Coumarins; Cysteine Endopeptidases; Diazomethane; Dipeptides; Fibroblasts; Humans; Hydrog

1997
Elevated levels of high-mobility-group chromosomal proteins, HMGA1, in murine skin carcinoma.
    Cancer letters, 2001, Nov-08, Volume: 173, Issue:1

    Topics: Acetic Acid; Animals; Benzo(a)pyrene; Biomarkers, Tumor; Blotting, Western; Carcinoma; Chromatograph

2001
Cocarcinogenic activity of peroxy compounds.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Benzoates; Carcinogens; Drug Synergism; Female;

1975
Destruction of tumour parenchyma in basal cell carcinoma by tumour-associated neutral proteases: a histochemical study.
    The British journal of dermatology, 1991, Volume: 124, Issue:3

    Topics: Carcinoma, Basal Cell; Coloring Agents; Cysteine Proteinase Inhibitors; Endopeptidases; Enzyme Activ

1991
Letter: Urea treatment of skin malignancies.
    Lancet (London, England), 1974, Feb-16, Volume: 1, Issue:7851

    Topics: Carcinoma, Basal Cell; Humans; Skin Neoplasms; Urea

1974
Urea treatment of skin malignancies.
    Lancet (London, England), 1974, Jan-26, Volume: 1, Issue:7848

    Topics: Adult; Aged; Biopsy; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Eyelid Neoplasms; Female; Huma

1974
Letter: Urea treatment of skin malignancies.
    Lancet (London, England), 1974, Mar-30, Volume: 1, Issue:7857

    Topics: Carcinoma, Basal Cell; Eyelid Neoplasms; Humans; Methods; Skin Neoplasms; Urea

1974
Letter: Urea treatment of skin malignancies.
    Lancet (London, England), 1974, Apr-20, Volume: 1, Issue:7860

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Skin Neoplasms; Urea

1974
Letter: Urea treatment of skin malignancies.
    Lancet (London, England), 1974, Jun-08, Volume: 1, Issue:7867

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Skin Neoplasms; Urea

1974
Antigenic differences between normal mouse epidermis and methylcholanthrene-induced squamous-cell carcinomas.
    Oncology, 1972, Volume: 26, Issue:1

    Topics: Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cross Reactions; Immunodiffusion; Immunoglobu

1972
[Studies on the organotropism of the carcinogenic effect of N-nitroso-N-methylurea (NMU) in rats].
    Experientia, 1969, Jan-15, Volume: 25, Issue:1

    Topics: Age Factors; Animals; Brain Neoplasms; Carcinogens; Esophageal Neoplasms; Hydrogen-Ion Concentration

1969
[Skin deformity tumors in young pigs induced by transplancental action of ethyl-nitroso-urea. Genesis of hidradenoma].
    Archiv fur Geschwulstforschung, 1969, Volume: 34, Issue:1

    Topics: Adenoma, Sweat Gland; Animals; Carcinogens; Female; Fetus; Hamartoma; Maternal-Fetal Exchange; Neopl

1969
Differences in the urea-extracted or fibrous proteins of mouse epidermis at various stages of malignant transformation.
    Oncology, 1974, Volume: 30, Issue:2

    Topics: Adenocarcinoma, Scirrhous; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Transformatio

1974
Antigenic changes in mouse epidermis at various stages of neoplastic transformation.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epithelium;

1972
[Histological changes in the mouse skin during the cancerogenic action of N-methyl-N-nitrosourea].
    Archiv fur Geschwulstforschung, 1966, Volume: 28, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Histological Techniques; Male; Mice; Neoplasms, Experimental; Nit

1966
Urea-extractable antigens in normal, benign, and neoplastic mouse epidermis.
    Oncology, 1970, Volume: 24, Issue:5

    Topics: Animals; Antigens; Blood Proteins; Carcinoma, Squamous Cell; Immune Sera; Immunodiffusion; Mice; Neo

1970
Primary malignant melanoma of the skin metastatic to the eye.
    American journal of ophthalmology, 1972, Volume: 74, Issue:1

    Topics: Adult; Blindness; Eye; Eye Neoplasms; Female; Humans; Inflammation; Male; Melanoma; Middle Aged; Neo

1972
Carcinogenic effect on N,N'-dimethylnitrosourea on syrian hamsters.
    Gan, 1971, Volume: 62, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Female; Injections, Subc

1971
Combination chemotherapy in malignant melanoma.
    Cancer, 1970, Volume: 26, Issue:2

    Topics: Adult; Bone Marrow Examination; Bone Neoplasms; Brain Neoplasms; Female; Hemoglobins; Humans; Inject

1970
The induction of tumours in the rat by a single oral dose of N-nitrosomethylurea.
    British journal of cancer, 1969, Volume: 23, Issue:1

    Topics: Animals; Female; Gastric Mucosa; Intestinal Neoplasms; Intestines; Jaw Neoplasms; Keratoacanthoma; K

1969