urea has been researched along with Blood Pressure, High in 381 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Excerpt | Relevance | Reference |
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" We conducted a prospective randomized study to examine the effects of the short-acting beta-1 blocker, landiolol, on hemodynamics during emergence from anesthesia in elderly patients with and without hypertension." | 9.14 | Effects of landiolol, a short-acting beta-1 blocker, on hemodynamic variables during emergence from anesthesia and tracheal extubation in elderly patients with and without hypertension. ( Kadoi, Y; Miyazaki, M; Saito, S, 2009) |
" In contrast, 2 mug/kg fentanyl frequently caused hypotension just before and 5 min after intubation." | 9.12 | The hemodynamic effects of landiolol, an ultra-short-acting beta1-selective blocker, on endotracheal intubation in patients with and without hypertension. ( Hidaka, K; Masuoka, M; Seki, S; Sugiura, S; Tsuchida, H, 2007) |
"To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril, on urinary albumin excretion and compared the results with those obtained in a control group of 25 type 2 diabetic patients treated with lisinopril only." | 9.10 | Combination of pentoxifylline with angiotensin converting enzyme inhibitors produces an additional reduction in microalbuminuria in hypertensive type 2 diabetic patients. ( Harmankaya, O; Seber, S; Yilmaz, M, 2003) |
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension." | 9.08 | The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995) |
"Patients with moderate to severe essential hypertension (mean untreated supine blood pressure 190/112 mm Hg) received once daily enalapril 20-40 mg or atenolol 50-100 mg, supplemented if required by hydrochlorothiazide 25-100 mg, in a randomized observer-blind trial." | 9.06 | Enalapril in moderate to severe hypertension: a comparison with atenolol. ( Burgess, J; Cooper, WD; Davidson, C; Fairhurst, G; Petrie, JC; Richardson, PJ; Robb, OJ; Trafford, J; Vandenburg, MJ; Webster, J, 1986) |
"41 patients (35 males and 6 females) with moderate hypertension were treated with a combination of methyldopa/hydrochlorothiazide/amiloride (M/HCT/A)." | 9.05 | [A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension]. ( Bolzano, K; Krempler, F; Sandhofer, F, 1984) |
"1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 9.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
"The dose response curve for 25, 50, 75 and 100 mg doses of chlorthalidone was studied in double blind fashion over an 8 week period in patients who presented with untreated mild hypertension." | 9.05 | Chlorthalidone in mild hypertension - dose response relationship. ( Humphries, IS; Mayhew, SR; Russell, JG, 1981) |
"Plasma urea and urate concentrations were determined daily for up to seven days in 40 pregnant women who had been admitted to hospital because of proteinuric hypertension and who were then allocated at random to either complete rest in bed or to being allowed to move freely in the ward." | 9.05 | The effect of rest and ambulation on plasma urea and urate levels in pregnant women with proteinuric hypertension. ( Agarwal, V; Mathews, DD; Shuttleworth, TP, 1980) |
"Prazosin (Minipress; Pfizer), a new antihypertensive agent, was investigated in 24 outpatients with uncontrolled hypertension." | 9.04 | Prazosin in the therapy of uncontrolled hypertension. ( Lubbe, WF, 1977) |
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension." | 9.04 | Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976) |
"The effect on BP of 100 and 200 mg spironolactone/day has been compared with that of methyl-dopa, 750 mg/day, and with combined treatment with both drugs in 32 patients with essential hypertension." | 9.04 | The effect of spironolactone (Aldactone) and methyldopa in low and normal renin hypertension. ( Giezendanner, L; Solheim, SB; Sundsfjord, JA, 1975) |
"To estimate urea and creatinine variations in dementia due to Alzheimer disease (AD) by way of a pharmacogenetic analysis of the anti-hypertensive effects of angiotensin-converting enzyme inhibitors (ACEis)." | 7.83 | Pharmacogenetic effects of angiotensin-converting enzyme inhibitors over age-related urea and creatinine variations in patients with dementia due to Alzheimer disease. ( Berretta, JM; Cardoso Smith, M; Ferreira Bertolucci, PH; Ferreira de Oliveira, F; Suchi Chen, E, 2016) |
" In the present study, blood triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP) breakdown pathway was evaluated in relation to uric acid concentration and xanthine dehydrogenase/xanthine oxidase (XDH/XO) in patients with essential hypertension, patients with chronic renal diseases on dialysis, and control individuals." | 7.80 | Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease. ( Boban, M; Bobana, MD; Cvetkovic, T; Deljanin-Ilic, M; Djindjic, B; Ilic, S; Jevtovic-Stoimenov, T; Kocic, G; Pavlovic, R; Radenkovic, S; Sokolovic, D; Stojanovic, D, 2014) |
"We report successful anesthetic management of a patient with pheochromocytoma using high-dose landiolol hydrochloride." | 7.80 | [Successful anesthetic management of a patient with giant pheochromocytoma using high-dose landiolol hydrochloride]. ( Kitano, M; Komasawa, N; Minami, T; Sawai, T, 2014) |
"Measurement of urinary electrolytes and urea revealed that an osmotic diuresis induced by urea derived principally by breakdown of endogenous protein was causative." | 7.79 | Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient. ( Anderson, A; Barrett, EJ, 2013) |
" We investigated the association between total protein intake, estimated from 24-h urinary urea excretion, and incident hypertension in Dutch men and women." | 7.79 | Twenty-four hour urinary urea excretion and 9-year risk of hypertension: the PREVEND study. ( Bakker, SJ; Brink, EJ; de Jong, PE; Engberink, MF; Gansevoort, RT; Geleijnse, JM; Tielemans, SM; van Baak, MA, 2013) |
"5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase (sEH) inhibitors and orally active agents for treating hypertension." | 7.79 | Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension. ( Aoki, T; Fuchi, N; Higashi, E; Kato, Y; Nakadera, Y; Nishimura, Y; Saburi, H; Watanabe, A; Yagi, M; Yamada, M, 2013) |
"1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea 14a (AR9281), a potent and selective soluble epoxide hydrolase inhibitor, was recently tested in a phase 2a clinical setting for its effectiveness in reducing blood pressure and improving insulin resistance in pre-diabetic patients." | 7.77 | 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. ( Aavula, BR; Anandan, SK; Cases, S; Chen, D; Cheng, Y; Do, ZN; Gless, R; Hammock, BD; Jones, PD; MacIntyre, DE; Mehra, U; Patel, DV; Sabry, J; Tran, V; Vincelette, J; Wang, YX; Waszczuk, J; Webb, HK; Whitcomb, R; White, K; Wong, KR; Zhang, LN, 2011) |
"We examined the dose-related effects of landiolol on hemodynamics during emergence from anesthesia of elderly patients with uncontrolled hypertension." | 7.77 | Adequacy of control of preoperative hypertension can affect landiolol-induced hemodynamic changes in elderly patients during emergence from anesthesia. ( Horiuchi, T; Kadoi, Y; Saito, S; Uchida, S, 2011) |
"Previous studies by our group demonstrated a striking relationship among arginine, nitric oxide production, and salt-sensitive hypertension in the Dahl/Rapp rat." | 7.70 | Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension. ( Chen, PY; Hamm, DA; Sanders, PW; Wood, PA, 1998) |
" Thus, for the first time we have studied an activity of two alternative pathways for the metabolism of L-arginine on the model of arterial hypertension." | 7.70 | [Disorders of endothelium-dependent vascular reactions and of the arginase and NO-synthase pathways of L-arginine metabolism in arterial hypertension]. ( Baziliuk, OV; Buzhanevich, OM; Kotsiuruba, AV; Sahach, VF, 2000) |
"023% NG-nitro-L-arginine (L-NNA), an inhibitor of nitric oxide synthesis, induced hypertension in normotensive Wistar-Kyoto rats (WKY)." | 7.69 | Fish protein-rich diet attenuates hypertension induced by dietary NG-nitro-L-arginine in normotensive Wistar-Kyoto rats. ( Deguan, GU; Gutierrez, OG; Ikeda, K; Nara, Y; Yamori, Y, 1994) |
"Hypertensive patients prescribed captopril while attending a hospital hypertension clinic were studied, to identify the benefits of the drug, its adverse effects and factors predisposing to them." | 7.68 | Adverse effects of captopril in hospital outpatients with hypertension. ( Breckenridge, A; Grimmer, M; Orme, M; Roberts, D; Walley, T; Winstanley, P, 1990) |
"Ten patients with mild to moderate hypertension were treated for 9 weeks with a tablet formulation of pinacidil." | 7.67 | Pinacidil monotherapy for hypertension. ( Ward, JW, 1984) |
"Thirty patients with moderate to severe, uncontrolled hypertension were treated with a captopril/frusemide combination." | 7.67 | Low dose, twice daily captopril and frusemide: a safe, effective and flexible third line treatment regimen for hypertension. ( Corrie, J; Flapan, AD; Lindsay, BA; Padfield, PL; Rademaker, M, 1989) |
" After favourable results obtained in a preliminary study using a combination of parenteral chlorpromazine and frusemide, a 5-year prospective study was conducted using this treatment to produce rapid reduction in blood pressure in patients with acute onset severe hypertension (blood pressure greater than 225/130 mmHg)." | 7.67 | Parenteral chlorpromazine and frusemide: safe and effective treatment for hypertensive emergencies. ( Lawson, AA; Nimmo, GR, 1986) |
"A single-blind study was carried out in 22 out-patients with mild to moderate hypertension to investigate the effects of piretanide capsules on systolic and diastolic blood pressure during standardized ergometric and isometric exercise." | 7.67 | The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension. ( Maass, L; Meywald, W; Rangoonwala, B; Verho, M, 1985) |
"The lithium efflux and sodium content of erythrocytes were measured in 75 patients with untreated essential hypertension." | 7.66 | The heterogeneity of essential hypertension. Relation between lithium efflux and sodium content of erythrocytes and a family history of hypertension. ( Clegg, G; Davidson, C; Morgan, DB, 1982) |
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 7.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
"Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 7.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
"Mifepristone was administered at doses of 300-1200 mg daily." | 6.77 | Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome. ( Biller, BM; Findling, JW; Fleseriu, M; Gross, C; Molitch, ME; Schteingart, DE, 2012) |
" They received in random order: placebo; tienilic acid 250 mg/day; propranolol 80 mg twice daily; and tienilic acid 250 mg/day combined with propranolol 80 mg twice daily." | 6.65 | Biochemical and haematological changes induced by tienilic acid combined with propranolol in essential hypertension. ( Bulpitt, CJ; Havard, CW; Pearson, RM, 1979) |
"Indapamide SR 1." | 6.41 | Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies. ( Weidmann, P, 2001) |
"Uric acid levels were similar in both groups during the first half of gestation." | 5.40 | [Serum uric acid levels and risk of developing preeclampsia]. ( Balconi, SM; Corominas, AI; Damiano, AE; Maskin, B; Palermo, M, 2014) |
" It is likely that diminished NO bioavailability in SAH contributes to cardiovascular complications." | 5.36 | Platelet aggregation in arterial hypertension: is there a nitric oxide-urea connection? ( Brunini, TM; Mann, GE; Mendes-Ribeiro, AC; Moss, MB; Siqueira, MA, 2010) |
" The aim of this study was to evaluate the capacity of different methods of stimulated sweating to reduce mean interdialytic weight gain (IWG), to improve blood pressure regulation, and potassium/urea balance." | 5.17 | Stimulated sweating as a therapy to reduce interdialytic weight gain and improve potassium balance in chronic hemodialysis patients: a pilot study. ( Burnier, M; El-Housseini, Y; Hachicha, J; Jarraya, F; Mahfoudh, H; Pruijm, M; Teta, D, 2013) |
" We conducted a prospective randomized study to examine the effects of the short-acting beta-1 blocker, landiolol, on hemodynamics during emergence from anesthesia in elderly patients with and without hypertension." | 5.14 | Effects of landiolol, a short-acting beta-1 blocker, on hemodynamic variables during emergence from anesthesia and tracheal extubation in elderly patients with and without hypertension. ( Kadoi, Y; Miyazaki, M; Saito, S, 2009) |
" In contrast, 2 mug/kg fentanyl frequently caused hypotension just before and 5 min after intubation." | 5.12 | The hemodynamic effects of landiolol, an ultra-short-acting beta1-selective blocker, on endotracheal intubation in patients with and without hypertension. ( Hidaka, K; Masuoka, M; Seki, S; Sugiura, S; Tsuchida, H, 2007) |
"To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied in 25 hypertensive type 2 diabetic patients with persistent microalbuminuria and normal renal function the impact of combining pentoxifylline with an angiotensin converting enzyme inhibitor, lisinopril, on urinary albumin excretion and compared the results with those obtained in a control group of 25 type 2 diabetic patients treated with lisinopril only." | 5.10 | Combination of pentoxifylline with angiotensin converting enzyme inhibitors produces an additional reduction in microalbuminuria in hypertensive type 2 diabetic patients. ( Harmankaya, O; Seber, S; Yilmaz, M, 2003) |
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension." | 5.08 | The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995) |
" Nine outpatients with mild and moderate hypertension were studied in the Cardiology Service of Vargas Hospital with a D1 agonist, piribedil, at 50-100 mg/day, orally, for 8 weeks, and with a D2 agonist, bromocriptine, at 2." | 5.07 | Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients. ( Alvarez, R; Luchsinger, A; Morillo, J; Pieretti, OH; Romero, E; Urbina, A; Velasco, M, 1992) |
"Patients with moderate to severe essential hypertension (mean untreated supine blood pressure 190/112 mm Hg) received once daily enalapril 20-40 mg or atenolol 50-100 mg, supplemented if required by hydrochlorothiazide 25-100 mg, in a randomized observer-blind trial." | 5.06 | Enalapril in moderate to severe hypertension: a comparison with atenolol. ( Burgess, J; Cooper, WD; Davidson, C; Fairhurst, G; Petrie, JC; Richardson, PJ; Robb, OJ; Trafford, J; Vandenburg, MJ; Webster, J, 1986) |
"The pharmacodynamic effects of torasemide, a new potent loop diuretic, were compared with those of furosemide in a double blind controlled study in 18 hypertensive patients with oedema of various origins." | 5.06 | Torasemide, a new potent diuretic. Double-blind comparison with furosemide. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1986) |
"41 patients (35 males and 6 females) with moderate hypertension were treated with a combination of methyldopa/hydrochlorothiazide/amiloride (M/HCT/A)." | 5.05 | [A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension]. ( Bolzano, K; Krempler, F; Sandhofer, F, 1984) |
"Thirty patients with essential hypertension participated in a double blind crossover trial in which they were randomly allocated to treatment with either once daily slow release metoprolol (200 mg) with placebo or once daily slow release metoprolol (200 mg) with chlorthalidone (25 mg)." | 5.05 | Effect on intra-arterial blood pressure of slow release metoprolol combined with placebo or chlorthalidone. ( Altman, DG; Gould, BA; Hornung, RS; Kieso, HA; Mann, S; Raftery, EB, 1983) |
"1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 5.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
"The dose response curve for 25, 50, 75 and 100 mg doses of chlorthalidone was studied in double blind fashion over an 8 week period in patients who presented with untreated mild hypertension." | 5.05 | Chlorthalidone in mild hypertension - dose response relationship. ( Humphries, IS; Mayhew, SR; Russell, JG, 1981) |
"Plasma urea and urate concentrations were determined daily for up to seven days in 40 pregnant women who had been admitted to hospital because of proteinuric hypertension and who were then allocated at random to either complete rest in bed or to being allowed to move freely in the ward." | 5.05 | The effect of rest and ambulation on plasma urea and urate levels in pregnant women with proteinuric hypertension. ( Agarwal, V; Mathews, DD; Shuttleworth, TP, 1980) |
"To determine the effects of potassium on blood pressure and factors affecting blood pressure, we conducted a randomized, placebo controlled trial of a potassium chloride-based substitute for table salt in 23 patients with mild to moderate essential hypertension." | 5.05 | Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure. ( Barnett, P; Cumming, AM; Hutcheson, MJ; Semple, PF; Zoccali, C, 1985) |
"Prazosin (Minipress; Pfizer), a new antihypertensive agent, was investigated in 24 outpatients with uncontrolled hypertension." | 5.04 | Prazosin in the therapy of uncontrolled hypertension. ( Lubbe, WF, 1977) |
"The effect of a six-week course of spironolactone 300 mg/day was examined in 25 unselected patients with essential hypertension." | 5.04 | Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism. ( Edmonds, CJ; Hoffbrand, BI; Smith, T, 1976) |
"The effect on BP of 100 and 200 mg spironolactone/day has been compared with that of methyl-dopa, 750 mg/day, and with combined treatment with both drugs in 32 patients with essential hypertension." | 5.04 | The effect of spironolactone (Aldactone) and methyldopa in low and normal renin hypertension. ( Giezendanner, L; Solheim, SB; Sundsfjord, JA, 1975) |
" We propose the following practical considerations to preserve RKF, especially in newly transitioned (incident) hemodialysis patients: (1) periodic monitoring of RKF in hemodialysis patients through urine volume and including residual urea clearance with dialysis adequacy and outcome markers such as anemia, fluid gains, minerals and electrolytes, nutritional, status and quality of life; (2) avoidance of nephrotoxic agents such as radiocontrast dye, nonsteroidal anti-inflammatory drugs, and aminoglycosides; (3) more rigorous hypertension control and minimizing intradialytic hypotensive episodes; (4) individualizing the initial dialysis prescription with consideration of an incremental/infrequent approach to hemodialysis initiation (e." | 4.93 | Preservation of residual kidney function in hemodialysis patients: reviving an old concept. ( Fishbane, S; Kalantar-Zadeh, K; Mathew, AT; Obi, Y, 2016) |
"Single factor analysis results suggest age, hypertension, diabetes, hyperlipidemia, disease of heart head blood-vessel, body mass index, vascularity index, flow index, and vascularization flow index, fasting blood sugar, triglyceride, total cholesterol, urea nitrogen, creatinine, uric acid, glomerular filtration rate differences statistically significant (P < 0." | 4.12 | Nomogram model for predicting early onset of chronic kidney disease using color Doppler region of interest technique. ( Gong, C; Ma, L; Shao, C; Xu, K; Yu, N; Zhang, L, 2022) |
" The present study aimed to develop a quantification model of biomarkers creatinine, urea, and glucose by means of selected peaks of these compounds, measured by Raman spectroscopy, and to estimate the concentration of these analytes in the urine of normal subjects (G_N), diabetic patients with hypertension (G_WOL) patients with chronic renal failure doing dialysis (G_D)." | 3.85 | Discrimination model applied to urinalysis of patients with diabetes and hypertension aiming at diagnosis of chronic kidney disease by Raman spectroscopy. ( Bispo, JAM; de Souza Vieira, EE; Fernandes, AB; Silveira, L, 2017) |
"To estimate urea and creatinine variations in dementia due to Alzheimer disease (AD) by way of a pharmacogenetic analysis of the anti-hypertensive effects of angiotensin-converting enzyme inhibitors (ACEis)." | 3.83 | Pharmacogenetic effects of angiotensin-converting enzyme inhibitors over age-related urea and creatinine variations in patients with dementia due to Alzheimer disease. ( Berretta, JM; Cardoso Smith, M; Ferreira Bertolucci, PH; Ferreira de Oliveira, F; Suchi Chen, E, 2016) |
" Hematocrit, urea, creatinine and microalbuminuria were analyzed, after which the HUGE formula was applied." | 3.81 | The H.U.G.E. Formula (Hematocrit, Urea, Sex) for Screening Chronic Kidney Disease (CKD) in an Age-Stratified General Population. ( Felix, FJ; Fernandez-Berges, D; Lozano, L; Macías, JF; Miranda, I; Robles, NR, 2015) |
" In the present study, blood triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP) breakdown pathway was evaluated in relation to uric acid concentration and xanthine dehydrogenase/xanthine oxidase (XDH/XO) in patients with essential hypertension, patients with chronic renal diseases on dialysis, and control individuals." | 3.80 | Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease. ( Boban, M; Bobana, MD; Cvetkovic, T; Deljanin-Ilic, M; Djindjic, B; Ilic, S; Jevtovic-Stoimenov, T; Kocic, G; Pavlovic, R; Radenkovic, S; Sokolovic, D; Stojanovic, D, 2014) |
"We report successful anesthetic management of a patient with pheochromocytoma using high-dose landiolol hydrochloride." | 3.80 | [Successful anesthetic management of a patient with giant pheochromocytoma using high-dose landiolol hydrochloride]. ( Kitano, M; Komasawa, N; Minami, T; Sawai, T, 2014) |
"Measurement of urinary electrolytes and urea revealed that an osmotic diuresis induced by urea derived principally by breakdown of endogenous protein was causative." | 3.79 | Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient. ( Anderson, A; Barrett, EJ, 2013) |
" We investigated the association between total protein intake, estimated from 24-h urinary urea excretion, and incident hypertension in Dutch men and women." | 3.79 | Twenty-four hour urinary urea excretion and 9-year risk of hypertension: the PREVEND study. ( Bakker, SJ; Brink, EJ; de Jong, PE; Engberink, MF; Gansevoort, RT; Geleijnse, JM; Tielemans, SM; van Baak, MA, 2013) |
"5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase (sEH) inhibitors and orally active agents for treating hypertension." | 3.79 | Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension. ( Aoki, T; Fuchi, N; Higashi, E; Kato, Y; Nakadera, Y; Nishimura, Y; Saburi, H; Watanabe, A; Yagi, M; Yamada, M, 2013) |
"In the present study, we examined the effects of soluble epoxide hydrolase (sEH) inhibition on the development of angiotensin II-dependent hypertension and on renal function in transgenic rats with inducible expression of the mouse renin gene (strain name Cyp1a1-Ren-2)." | 3.77 | Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. ( Červenka, L; Hammock, BD; Honetschlägerová, Z; Husková, Z; Hwang, SH; Imig, JD; Kopkan, L; Kramer, HJ; Sporková, A; Tsai, HJ; Vaňourková, Z, 2011) |
"1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea 14a (AR9281), a potent and selective soluble epoxide hydrolase inhibitor, was recently tested in a phase 2a clinical setting for its effectiveness in reducing blood pressure and improving insulin resistance in pre-diabetic patients." | 3.77 | 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. ( Aavula, BR; Anandan, SK; Cases, S; Chen, D; Cheng, Y; Do, ZN; Gless, R; Hammock, BD; Jones, PD; MacIntyre, DE; Mehra, U; Patel, DV; Sabry, J; Tran, V; Vincelette, J; Wang, YX; Waszczuk, J; Webb, HK; Whitcomb, R; White, K; Wong, KR; Zhang, LN, 2011) |
"We examined the dose-related effects of landiolol on hemodynamics during emergence from anesthesia of elderly patients with uncontrolled hypertension." | 3.77 | Adequacy of control of preoperative hypertension can affect landiolol-induced hemodynamic changes in elderly patients during emergence from anesthesia. ( Horiuchi, T; Kadoi, Y; Saito, S; Uchida, S, 2011) |
"We examined a novel therapeutic approach for hypertension, a small-molecule direct inhibitor of smooth muscle myosin, CK-2018448 (CK-448), which is an N,N'-alkylurea (U." | 3.77 | Inhibition of smooth muscle myosin as a novel therapeutic target for hypertension. ( Abarzúa, P; Dhar, SK; Ho, D; Jia, Z; Malik, FI; Morgans, DJ; Pannirselvam, M; Vatner, SF; Wang, X; Zhao, X, 2011) |
" Plasma concentrations of creatinine, urea, electrolytes or osmolality also did not differ." | 3.76 | No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers. ( Amann, K; Boltze, J; Dötsch, J; Mühle, A; Mühle, C; Nüsken, KD; Schneider, H, 2010) |
"The Hypertension in the Very Elderly Trial (HYVET) is a randomized double-blind trial of active antihypertensive treatment (indapamide 1." | 3.75 | Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET). ( Banya, W; Beckett, NS; Bulpitt, CJ; Burch, L; Dumitrascu, D; Fletcher, AE; Liu, L; Nikitin, Y; Peters, R; Staessen, JA; Stoyanovsky, V; Wang, JG, 2009) |
" On the other hand, landiolol was effective for treating intraoperative hypertension and tachycardia." | 3.75 | [General anesthesia for cesarean section in a patient with moyamoya disease]. ( Asano, N; Ishiyama, T; Matsukawa, T; Sugihara, K, 2009) |
" Univariate analysis documented age, ASA score, diabetes mellitus, chronic hypertension, the use of diuretics and NSAID, anemia, and an increased value of plasma urea as risk factors." | 3.75 | [Risk factors for renal dysfunction after total hip arthroplasty]. ( Aveline, C; Bonnet, F; Cognet, F; Le Hetet, H; Leroux, A; Vautier, P, 2009) |
" Evaluation of renal function included pre and post-nephrectomy urinalysis, determination of microalbuminuria, serum creatinine, blood urea, 24 hr urinary protein and creatinine estimation and calculation of creatinine clearance." | 3.74 | Risk of live kidney donation--Indian perspective. ( Narayen, G; Sahay, M, 2007) |
"To investigate the disturbances of serum and red cell electrolytes in association with membrane Na(+)-K(+)- ATPase activity as well as the status of serum Urea, Creatinine and osmolality in normotensive diabetic and hypertensive diabetic patients." | 3.73 | Ionic and allied variations in normotensive and hypertensive diabetic patients. ( Jawed, M; Mahboob, T; Shahid, SM, 2005) |
"Previous studies by our group demonstrated a striking relationship among arginine, nitric oxide production, and salt-sensitive hypertension in the Dahl/Rapp rat." | 3.70 | Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension. ( Chen, PY; Hamm, DA; Sanders, PW; Wood, PA, 1998) |
" Thus, for the first time we have studied an activity of two alternative pathways for the metabolism of L-arginine on the model of arterial hypertension." | 3.70 | [Disorders of endothelium-dependent vascular reactions and of the arginase and NO-synthase pathways of L-arginine metabolism in arterial hypertension]. ( Baziliuk, OV; Buzhanevich, OM; Kotsiuruba, AV; Sahach, VF, 2000) |
"023% NG-nitro-L-arginine (L-NNA), an inhibitor of nitric oxide synthesis, induced hypertension in normotensive Wistar-Kyoto rats (WKY)." | 3.69 | Fish protein-rich diet attenuates hypertension induced by dietary NG-nitro-L-arginine in normotensive Wistar-Kyoto rats. ( Deguan, GU; Gutierrez, OG; Ikeda, K; Nara, Y; Yamori, Y, 1994) |
"We explored the role of angiotensin II and vasopressin in the maintenance of blood pressure during the nephrotic syndrome of adriamycin-induced nephropathy in rats." | 3.69 | Pressor mechanisms in adriamycin-induced nephropathy with hypertension in rats. ( Ferrari-Spadotto, A; Franco, R; Gavras, H; Gavras, I; Georgette, J; Gut, A, 1994) |
"In a group of 80 women in their 3rd trimester of pregnancy (29-36 weeks) 50 of whom were with hypertension and 30 healthy, the blood serum was studied for concentrations of urea, uric acid, creatinine, total proteins and electrolytes: sodium and potassium." | 3.69 | [Kidney function in pregnant women with arterial hypertension]. ( Banaczek, Z, 1995) |
"In a study of 50 women in their 3rd trimester of pregnancy complicated by hypertension of different etiology, the blood serum was examined for concentrations of urea, uric acid, creatinine, total proteins, sodium and potassium." | 3.69 | [The effect of hypertension severity in pregnant women and during birth on renal function]. ( Banaczek, Z, 1995) |
" Urinary excretion rates of calcium, sodium, chloride, potassium, urinary calcium/creatinine index, the fractional excretion of sodium, potassium and uric acid, the creatinine clearance and serum values of creatinine, urea, uric acid, electrolytes, total proteins, parathormone (intact molecule), plasma renin activity, aldosterone, glucose, and insulin (fasting and after an oral glucose load) were performed in every patient and control subject." | 3.69 | Urinary calcium excretion in treated and untreated essential hypertension. ( Navarro-Antolin, J; Orte, L; Ortuño, J; Quereda, C; Sabater, J; Villafruela, JJ, 1996) |
"Hypertensive patients prescribed captopril while attending a hospital hypertension clinic were studied, to identify the benefits of the drug, its adverse effects and factors predisposing to them." | 3.68 | Adverse effects of captopril in hospital outpatients with hypertension. ( Breckenridge, A; Grimmer, M; Orme, M; Roberts, D; Walley, T; Winstanley, P, 1990) |
"Ten patients with mild to moderate hypertension were treated for 9 weeks with a tablet formulation of pinacidil." | 3.67 | Pinacidil monotherapy for hypertension. ( Ward, JW, 1984) |
"Thirty patients with moderate to severe, uncontrolled hypertension were treated with a captopril/frusemide combination." | 3.67 | Low dose, twice daily captopril and frusemide: a safe, effective and flexible third line treatment regimen for hypertension. ( Corrie, J; Flapan, AD; Lindsay, BA; Padfield, PL; Rademaker, M, 1989) |
" After favourable results obtained in a preliminary study using a combination of parenteral chlorpromazine and frusemide, a 5-year prospective study was conducted using this treatment to produce rapid reduction in blood pressure in patients with acute onset severe hypertension (blood pressure greater than 225/130 mmHg)." | 3.67 | Parenteral chlorpromazine and frusemide: safe and effective treatment for hypertensive emergencies. ( Lawson, AA; Nimmo, GR, 1986) |
"A single-blind study was carried out in 22 out-patients with mild to moderate hypertension to investigate the effects of piretanide capsules on systolic and diastolic blood pressure during standardized ergometric and isometric exercise." | 3.67 | The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension. ( Maass, L; Meywald, W; Rangoonwala, B; Verho, M, 1985) |
"The lithium efflux and sodium content of erythrocytes were measured in 75 patients with untreated essential hypertension." | 3.66 | The heterogeneity of essential hypertension. Relation between lithium efflux and sodium content of erythrocytes and a family history of hypertension. ( Clegg, G; Davidson, C; Morgan, DB, 1982) |
"22 of 31 residents of a Somerset village where soil levels of cadmium were high had raised blood-cadmium levels, and some had clinical and biochemical findings (including hypertension and biochemical evidence of renal tubular damage) indicating toxic effects which could be attributed to the metal." | 3.66 | Evidence of cadmium toxicity in a population living in a zinc-mining area. Pilot survey of Shipham residents. ( Carruthers, M; Smith, B, 1979) |
"Symptoms due to orthostatic and exertional hypotension occurred in 23-4 per cent of 448 hypertensive patients treated with guanethidine, debrisoquine, or bethanidine." | 3.65 | Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure. ( Smith, AJ; Talbot, S, 1975) |
"Studies were carried out in 69 patients with essential hypertension to examine the relationship between changes in plasma renin activity (PRA) and arterial pressure (BP) in response to a beta-adrenergic blocking agent, propranolol." | 3.65 | Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension. ( Bravo, EL; Dustan, HP; Lewis, JW; Tarazi, RC, 1975) |
"Patients with chronic renal failure and on chronic intermittent hemodialysis have several metabolic risks such as retention of urea and other products of nitrogen metabolism, catabolism, acidosis, edema, dehydration, hyper- and hypotension, hyperkalemia, renal osteopathy, and renal anemia." | 3.65 | [Dangers of a wrong diet in patients with renal insufficiency in the predialytic state or during chronic hemodialysis]. ( Hecking, E; Mader, HJ; Zobel, R, 1977) |
"During the onset of malignant hypertension (MH) in rats treated with deoxycorticosterone trimethylacetate (DOC), plasma arginine vasopressin (AVP) concentrations increase tenfold as a consequence of hypovolemia and hyperosmolality." | 3.65 | Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension. ( Haack, D; Möhring, B; Möhring, J; Petri, M, 1977) |
"Both the average serum uric acid and annual increment were determined in 250 treated patients attending a hypertension clinic." | 3.65 | Serum uric acid in hypertensive patients. ( Bulpitt, CJ, 1975) |
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 3.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
"Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 3.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
"Hypertension is a long-term medical condition in which the blood pressure is gradually elevated." | 2.90 | Effects of Olive Leaf Extract on Metabolic Response, Liver and Kidney Functions and Inflammatory Biomarkers in Hypertensive Patients. ( Esfahani, Z; Javadi, H; Mehdi Mirhashemi, S; Reza Memarzadeh, M; Yaghoobzadeh, H, 2019) |
"Mifepristone was administered at doses of 300-1200 mg daily." | 2.77 | Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome. ( Biller, BM; Findling, JW; Fleseriu, M; Gross, C; Molitch, ME; Schteingart, DE, 2012) |
"Renal hemodynamics was measured before and after 12." | 2.72 | Pharmacodynamics and pharmacokinetics of the urotensin II receptor antagonist palosuran in macroalbuminuric, diabetic patients. ( Bohnemeier, H; Chadha-Boreham, H; Dingemanse, J; Halabi, A; Jungnik, A; Krähenbühl, S; Sidharta, PN; Wagner, FD, 2006) |
"Thirty hypertensive diabetic nephropathy patients with moderate hypertension were studied." | 2.70 | Comparative effect of lisinopril and lacidipine on urinary albumin excretion in patients with type 11 diabetic nephropathy. ( Arije, A; Finomo, FO; Kadiri, S; Olatosin, AO; Salako, BL, 2002) |
"5 mg, 25 mg, and 50 mg hydrochlorothiazide combined with 400 mg acebutolol was assessed." | 2.65 | Lack of effect of beta-blocker on flat dose response to thiazide in hypertension: efficacy of low dose thiazide combined with beta-blocker. ( Banks, RA; Bayliss, J; MacGregor, GA; Markandu, ND; Roulston, J, 1983) |
" They received in random order: placebo; tienilic acid 250 mg/day; propranolol 80 mg twice daily; and tienilic acid 250 mg/day combined with propranolol 80 mg twice daily." | 2.65 | Biochemical and haematological changes induced by tienilic acid combined with propranolol in essential hypertension. ( Bulpitt, CJ; Havard, CW; Pearson, RM, 1979) |
"In our clinic, 25 patients with Fournier's gangrene were treated between 1995 and 2000." | 2.42 | Fournier's gangrene: experience with 25 patients and use of Fournier's gangrene severity index score. ( Arslan, M; Ayder, AR; Suelozgen, T; Yeniyol, CO, 2004) |
"Indapamide SR 1." | 2.41 | Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies. ( Weidmann, P, 2001) |
"Xipamide is a diuretic derived from salicylic acid and has a structural resemblance to chlorthalidone." | 2.37 | Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. ( Brogden, RN; Prichard, BN, 1985) |
"Despite the high fatality rate from melioidosis, there is a minimal published study about the disease in Malaysia." | 1.62 | The Cox model of predicting mortality among melioidosis patients in Northern Malaysia: A retrospective study. ( Chan, HK; Hassan, MRA; Mardhiah, K; Naing, NN; Wan-Arfah, N, 2021) |
"In patients with COPD, only serum creatinine was higher (81." | 1.48 | Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis. ( Döme, B; Fábián, K; Fejes, D; Kakuk, T; Moldvay, J; Pipek, O; Prés, L; Puskás, R; Rojkó, L; Szállási, Z; Szegedi, Z, 2018) |
"Hypertension was induced by L-N(G)-nitroarginine methyl ester (L-NAME) and hypercholesterolemia was induced by feeding rats with a diet containing 1% cholesterol." | 1.46 | Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms. ( Abd-Eldayem, AM; Abdel-Zaher, AO; El-Refaiy, AEM; Farghaly, HSM, 2017) |
"Hypertension is one the most common causes of chronic kidney disease (CKD)." | 1.42 | Comparative assessment of neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C as early biomarkers for early detection of renal failure in patients with hypertension. ( Ghanei, E; Gharishvandi, F; Kazerouni, F; Nasiri, M; Rahimipour, A, 2015) |
"Uric acid levels were similar in both groups during the first half of gestation." | 1.40 | [Serum uric acid levels and risk of developing preeclampsia]. ( Balconi, SM; Corominas, AI; Damiano, AE; Maskin, B; Palermo, M, 2014) |
"Hypertension is highly prevalent among renal transplant recipients (RTR) and a risk factor for graft failure and cardiovascular events." | 1.39 | Dietary protein, blood pressure and renal function in renal transplant recipients. ( Bakker, SJ; Brink, EJ; Engberink, MF; Gans, RO; Navis, G; van Baak, MA; van den Berg, E, 2013) |
" In contrast, c-AUCB treatment significantly reduced BP, increased intrarenal bioavailability of EETs and significantly suppressed AngII levels in TGR." | 1.39 | Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. ( Cervenka, L; Hammock, BD; Huskova, Z; Hwang, SH; Imig, JD; Kitada, K; Kramer, HJ; Varcabova, S, 2013) |
" It is likely that diminished NO bioavailability in SAH contributes to cardiovascular complications." | 1.36 | Platelet aggregation in arterial hypertension: is there a nitric oxide-urea connection? ( Brunini, TM; Mann, GE; Mendes-Ribeiro, AC; Moss, MB; Siqueira, MA, 2010) |
"Long-term hypertension was seen in 43% of the patients, but left ventricular hypertrophy decreased during the study period." | 1.36 | Normal growth and intravascular volume status with good metabolic control during peritoneal dialysis in infancy. ( Happonen, JM; Holmberg, C; Hölttä, T; Laakkonen, H; Marttinen, E; Paganus, A; Rönnholm, K, 2010) |
" 1,3-dicyclohexylurea (DCU), a potent sEH inhibitor, lowers systemic blood pressure in spontaneously hypertensive rats when dosed intraperitoneally." | 1.35 | Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. ( Chiang, PC; Fujiwara, H; Ghosh, S; Roberds, SL; Selbo, JG; Wahlstrom, JL, 2008) |
"Sleep disorders are very frequent in hemodialyzed patients, but the relationship between these disorders and water withdrawal, urea removal and comorbidities has not been sufficiently clarified." | 1.33 | Sleep disorders in hemodialyzed patients--the role of comorbidities. ( De Santo, RM; Di Iorio, BR; Lucidi, F; Violani, C, 2005) |
"Hypertension was present in 31 patients but only improved in 4 (7%)." | 1.33 | Immunosuppression based on mycophenolate mofetil in stable liver transplanted patients. ( Andino, R; Bilbao, I; Cancino, J; Castells, L; Castro, E; Dopazo, C; Margarit, C; Pou, L; Rojas, L, 2006) |
"Secondary hyperparathyroidism is a common complication of renal failure." | 1.32 | Secondary hyperparathyroidism in chronic hemodialysis patients: prevalence and race. ( Elhwairis, H; Narra, S; Osama, S; Owda, A; Towery, H, 2003) |
"Many end stage renal disease (ESRD) patients get their first nephrologic care under critical clinical conditions and without previous diagnosis of chronic renal failure (CRF), a situation even worse than the late referral of CRF patients for nephrologic treatment." | 1.32 | Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital. ( Abdulkader, RC; Burdmann, EA; Oliveira, GM; Zanetta, DM, 2003) |
"Urinary VEGF excretions increased as diabetic nephropathy advanced." | 1.32 | Plasma and urinary vascular endothelial growth factor and diabetic nephropathy in Type 2 diabetes mellitus. ( Baik, SH; Cha, DR; Choi, DS; Choi, KM; Han, KH; Han, SY; Ji, YH; Kang, YS; Kim, DL; Kim, KB; Kim, NH; Kim, SG, 2004) |
"Acute hypertension was induced by phenylephrine." | 1.31 | Effects of acute and chronic hypertension on the labyrinthine barriers in rat. ( Amiel, C; Fernandes, I; Ferrary, E; Loiseau, A; Mosnier, I; Sterkers, O; Teixeira, M, 2001) |
"Treatment with captopril also reduced the development of glomerular sclerosis." | 1.29 | Effects of captopril and hydralazine on progression of adriamycin nephropathy in spontaneously hypertensive rats. ( Bogdanovic, G; Djukanovic, L; Jovanovic, D; Kartaljevic, G; Starcevic, A; Susic, D; Varagic, J, 1994) |
"Nimodipine-treated as well as parathyroidectomied animals showed significantly fewer hypertensive cerebral lesions." | 1.28 | Therapy of diseased stroke-prone spontaneously hypertensive rats with nimodipine. ( Kazda, S; Lenz, P; Luckhaus, G; Stasch, JP, 1990) |
"SHR with acute renal failure had significantly lower mean arterial blood pressures and heart rates." | 1.27 | Cardiovascular responses in spontaneously hypertensive rats with acute renal failure. ( Bowmer, CJ; Brown, GM; Yates, MS, 1984) |
"Mild hypertension was already observed at 8 weeks of age." | 1.27 | Development of hypertension and proteinuria with age in fawn-hooded rats. ( de Jong, W; Kuijpers, MH; Provoost, AP, 1986) |
"Bacteriuria was not associated with deteriorating renal function determined by serial plasma creatinine estimations." | 1.26 | A prospective study of patients with radiological pyelonephritis, papillary necrosis and obstructive atrophy. ( Gower, PE, 1976) |
"The presence of papilledema is important in making the diagnosis; however, important exceptions exist." | 1.25 | Raised intracranial pressure. Diagnosis and management. ( Saper, JR; Yosselson, S, 1975) |
"Renal failure and hypertension have been reported and long-term follow up is necessary to clarify the natural history of the disease." | 1.25 | Recurrent haematuria and mesangial IgA deposition. ( Brown, GW; Davies, DR; Jones, NF; Tighe, JR, 1973) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 221 (58.01) | 18.7374 |
1990's | 38 (9.97) | 18.2507 |
2000's | 53 (13.91) | 29.6817 |
2010's | 56 (14.70) | 24.3611 |
2020's | 13 (3.41) | 2.80 |
Authors | Studies |
---|---|
Mondragón-Huerta, CG | 1 |
Bautista-Pérez, R | 1 |
Baiza-Gutman, LA | 1 |
Escobar-Sánchez, ML | 1 |
Valle-Mondragón, LD | 1 |
Salas-Garrido, CG | 1 |
Castro-Moreno, P | 1 |
Ibarra-Barajas, M | 1 |
Le, XT | 1 |
Thi Nguyen, LT | 1 |
Nguyen, PT | 1 |
Nguyen, TV | 1 |
Nguyen, HV | 1 |
Nguyet Pham, HT | 1 |
Tran, HN | 1 |
Hoang, TD | 1 |
Van Le, D | 1 |
Matsumoto, K | 1 |
Lai, JS | 1 |
Tan, CK | 1 |
Yusoff, K | 1 |
Cheah, SC | 1 |
Han, WW | 1 |
Wang, XR | 1 |
He, YF | 1 |
Zhang, HS | 1 |
Cong, X | 1 |
Xiang, RL | 1 |
Wu, LL | 1 |
Yu, GY | 1 |
Liu, LM | 1 |
Zhang, Y | 1 |
Zhang, L | 1 |
Xu, K | 1 |
Ma, L | 1 |
Shao, C | 1 |
Gong, C | 1 |
Yu, N | 1 |
Chen, N | 1 |
Fan, F | 1 |
Geng, J | 1 |
Yang, Y | 1 |
Gao, Y | 1 |
Jin, H | 1 |
Chu, Q | 1 |
Yu, D | 1 |
Wang, Z | 1 |
Shi, J | 1 |
Santos, ISR | 1 |
Martin-Pastor, M | 1 |
Tavares Júnior, AG | 1 |
Queiroz, KA | 1 |
da Silva Sólon, LG | 1 |
Sousa, FFO | 1 |
Bagheri, B | 1 |
Radmard, N | 1 |
Faghani-Makrani, A | 1 |
Rasouli, M | 1 |
Lüscher, TF | 1 |
Javadi, H | 1 |
Yaghoobzadeh, H | 1 |
Esfahani, Z | 1 |
Reza Memarzadeh, M | 1 |
Mehdi Mirhashemi, S | 1 |
Gilinsky, MA | 1 |
Polityko, YK | 1 |
Markel, AL | 1 |
Latysheva, TV | 1 |
Samson, AO | 1 |
Polis, B | 1 |
Naumenko, SE | 1 |
Kuma, A | 1 |
Wang, XH | 1 |
Klein, JD | 1 |
Tan, L | 1 |
Naqvi, N | 1 |
Rianto, F | 1 |
Huang, Y | 2 |
Yu, M | 1 |
Sands, JM | 1 |
Romão da Silva, LF | 1 |
de Oliveira, Y | 1 |
de Souza, EL | 1 |
de Luna Freire, MO | 1 |
Braga, VA | 1 |
Magnani, M | 1 |
de Brito Alves, JL | 1 |
Caputo, C | 1 |
Ciabattoni, M | 1 |
Garneri, D | 1 |
Repetto, M | 1 |
Santoni, O | 1 |
Tarroni, A | 1 |
Tosetti, F | 1 |
Vigo, EC | 1 |
Mancuso, G | 1 |
Nesovic Ostojic, J | 1 |
Ivanov, M | 2 |
Mihailovic-Stanojevic, N | 3 |
Karanovic, D | 1 |
Kovacevic, S | 1 |
Brkic, P | 1 |
Zivotic, M | 1 |
Vajic, UJ | 1 |
Jovovic, D | 3 |
Jeremic, R | 1 |
Ljubojevic-Holzer, S | 1 |
Miloradovic, Z | 3 |
Mardhiah, K | 1 |
Wan-Arfah, N | 1 |
Naing, NN | 1 |
Hassan, MRA | 1 |
Chan, HK | 1 |
Fábián, K | 1 |
Puskás, R | 1 |
Kakuk, T | 1 |
Prés, L | 1 |
Fejes, D | 1 |
Szegedi, Z | 1 |
Rojkó, L | 1 |
Szállási, Z | 1 |
Döme, B | 1 |
Pipek, O | 1 |
Moldvay, J | 1 |
de Souza Vieira, EE | 1 |
Bispo, JAM | 1 |
Silveira, L | 2 |
Fernandes, AB | 2 |
Smeda, JS | 1 |
Daneshtalab, N | 1 |
Abdel-Zaher, AO | 1 |
Farghaly, HSM | 1 |
El-Refaiy, AEM | 1 |
Abd-Eldayem, AM | 1 |
Nunes, DV | 1 |
Costa, CA | 1 |
De Bem, GF | 1 |
Cordeiro, VS | 1 |
Santos, IB | 1 |
Carvalho, LC | 1 |
Jordão, AK | 1 |
Cunha, AC | 1 |
Ferreira, VF | 1 |
Moura, RS | 1 |
Resende, AC | 1 |
Ognibene, DT | 1 |
Seifi, B | 1 |
Sajedizadeh, A | 1 |
Kadkhodaee, M | 1 |
Ranjbaran, M | 1 |
Anderson, A | 1 |
Barrett, EJ | 1 |
Shahid, SM | 3 |
Jawed, M | 2 |
Mahboob, T | 3 |
Tielemans, SM | 1 |
Geleijnse, JM | 1 |
van Baak, MA | 2 |
Engberink, MF | 2 |
Brink, EJ | 2 |
de Jong, PE | 1 |
Gansevoort, RT | 1 |
Bakker, SJ | 2 |
Bispo, JA | 1 |
de Sousa Vieira, EE | 1 |
Kato, Y | 1 |
Fuchi, N | 1 |
Saburi, H | 1 |
Nishimura, Y | 1 |
Watanabe, A | 1 |
Yagi, M | 1 |
Nakadera, Y | 1 |
Higashi, E | 1 |
Yamada, M | 1 |
Aoki, T | 1 |
Boban, M | 1 |
Kocic, G | 1 |
Radenkovic, S | 1 |
Pavlovic, R | 1 |
Cvetkovic, T | 1 |
Deljanin-Ilic, M | 1 |
Ilic, S | 1 |
Bobana, MD | 1 |
Djindjic, B | 1 |
Stojanovic, D | 1 |
Sokolovic, D | 1 |
Jevtovic-Stoimenov, T | 1 |
Kitano, M | 1 |
Komasawa, N | 1 |
Sawai, T | 1 |
Minami, T | 1 |
Frenkel, NJ | 1 |
Vogt, L | 2 |
De Rooij, SE | 1 |
Trimpert, C | 1 |
Levi, MM | 1 |
Deen, PM | 1 |
van den Born, BJ | 1 |
Corominas, AI | 1 |
Balconi, SM | 1 |
Palermo, M | 1 |
Maskin, B | 1 |
Damiano, AE | 1 |
Olenskaia, TL | 1 |
Konevalova, NIu | 1 |
Rapoport, SI | 1 |
Proshchaev, KI | 1 |
Kozlov, KL | 1 |
Korobov, GD | 1 |
Gharishvandi, F | 1 |
Kazerouni, F | 1 |
Ghanei, E | 1 |
Rahimipour, A | 1 |
Nasiri, M | 1 |
Robles, NR | 1 |
Felix, FJ | 1 |
Lozano, L | 1 |
Miranda, I | 1 |
Fernandez-Berges, D | 1 |
Macías, JF | 1 |
Wang, QZ | 1 |
Gao, HQ | 1 |
Liang, Y | 1 |
Zhang, J | 1 |
Wang, J | 1 |
Qiu, J | 1 |
Linz, B | 1 |
Hohl, M | 1 |
Reil, JC | 1 |
Böhm, M | 1 |
Linz, D | 1 |
Courand, PY | 1 |
Lesiuk, C | 1 |
Milon, H | 1 |
Defforges, A | 1 |
Fouque, D | 1 |
Harbaoui, B | 1 |
Lantelme, P | 1 |
Mathew, AT | 1 |
Fishbane, S | 1 |
Obi, Y | 1 |
Kalantar-Zadeh, K | 1 |
Ferreira de Oliveira, F | 1 |
Berretta, JM | 1 |
Suchi Chen, E | 1 |
Cardoso Smith, M | 1 |
Ferreira Bertolucci, PH | 1 |
Duan, L | 1 |
Su, Q | 1 |
Lin, Q | 1 |
Liu, W | 1 |
Luo, J | 1 |
Yu, B | 1 |
He, Y | 1 |
Qian, H | 1 |
Liu, Y | 1 |
Chen, J | 1 |
Shi, G | 1 |
Damian, DJ | 1 |
McNamee, R | 1 |
Carr, M | 1 |
Mene-Afejuku, TO | 1 |
Balogun, MO | 1 |
Akintomide, AO | 2 |
Adebayo, RA | 1 |
Fujita, Y | 1 |
Shimizu, T | 1 |
Matsumoto, A | 1 |
Aoki, M | 1 |
Nemati, E | 1 |
Ghanbarpour, F | 1 |
Taheri, S | 1 |
Einollahi, B | 1 |
Kasagami, T | 1 |
Kim, IH | 1 |
Tsai, HJ | 2 |
Nishi, K | 1 |
Hammock, BD | 7 |
Morisseau, C | 2 |
Bulpitt, CJ | 8 |
Beckett, NS | 1 |
Peters, R | 1 |
Banya, W | 1 |
Liu, L | 1 |
Wang, JG | 1 |
Stoyanovsky, V | 1 |
Dumitrascu, D | 1 |
Nikitin, Y | 1 |
Staessen, JA | 1 |
Burch, L | 1 |
Fletcher, AE | 1 |
Asano, N | 1 |
Ishiyama, T | 1 |
Sugihara, K | 1 |
Matsukawa, T | 1 |
Huynh, NN | 1 |
Andrews, KL | 1 |
Head, GA | 1 |
Khong, SM | 1 |
Mayorov, DN | 1 |
Murphy, AJ | 1 |
Lambert, G | 1 |
Kiriazis, H | 1 |
Xu, Q | 1 |
Du, XJ | 1 |
Chin-Dusting, JP | 1 |
Manhiani, M | 1 |
Quigley, JE | 1 |
Knight, SF | 1 |
Tasoobshirazi, S | 1 |
Moore, T | 1 |
Brands, MW | 1 |
Imig, JD | 4 |
Moss, MB | 1 |
Siqueira, MA | 1 |
Mann, GE | 1 |
Brunini, TM | 1 |
Mendes-Ribeiro, AC | 1 |
Shen, HC | 1 |
Ding, FX | 1 |
Deng, Q | 1 |
Xu, S | 1 |
Chen, HS | 1 |
Tong, X | 1 |
Tong, V | 1 |
Zhang, X | 1 |
Chen, Y | 1 |
Zhou, G | 1 |
Pai, LY | 1 |
Alonso-Galicia, M | 1 |
Zhang, B | 1 |
Roy, S | 1 |
Tata, JR | 1 |
Berger, JP | 1 |
Colletti, SL | 1 |
Aveline, C | 1 |
Leroux, A | 1 |
Vautier, P | 1 |
Cognet, F | 1 |
Le Hetet, H | 1 |
Bonnet, F | 1 |
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England, P | 1 |
Lorimer, JD | 1 |
Ferguson, JC | 1 |
Govan, AD | 1 |
Luchsinger, A | 1 |
Velasco, M | 1 |
Urbina, A | 1 |
Morillo, J | 1 |
Romero, E | 1 |
Alvarez, R | 1 |
Pieretti, OH | 1 |
Blagg, CR | 1 |
Hüting, J | 1 |
Charra, B | 1 |
Calemard, E | 1 |
Ruffet, M | 1 |
Chazot, C | 1 |
Terrat, JC | 1 |
Vanel, T | 1 |
Laurent, G | 1 |
Damase-Michel, C | 1 |
Girolami, JP | 1 |
Bascands, JL | 1 |
Tran, MA | 1 |
Moatti, JP | 1 |
Pecher, C | 1 |
Berthet, P | 1 |
Tarrade, T | 1 |
Montastruc, JL | 1 |
Tykarski, A | 1 |
Capewell, S | 1 |
Wathen, CG | 1 |
Hannan, WJ | 1 |
Muir, AL | 1 |
Michel, JB | 1 |
Sayah, S | 1 |
Guettier, C | 1 |
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Philippe, M | 1 |
Gonzalez, MF | 1 |
Carelli, C | 1 |
Galen, FX | 1 |
Menard, J | 1 |
Corvol, P | 1 |
Walley, T | 1 |
Winstanley, P | 1 |
Roberts, D | 1 |
Grimmer, M | 1 |
Orme, M | 1 |
Lenz, P | 1 |
Luckhaus, G | 1 |
Stasch, JP | 1 |
Kazda, S | 1 |
Folberth, CG | 1 |
Stauss, H | 1 |
Kopf, D | 1 |
Waldherr, R | 1 |
Baldauf, G | 1 |
Unger, T | 1 |
Selgas, R | 1 |
Muñoz, J | 1 |
Cigarran, S | 1 |
Ramos, P | 1 |
L-Revuelta, K | 1 |
Escuin, F | 1 |
Miguel, JL | 1 |
Karvé, MD | 1 |
Shamarin, VM | 1 |
Vinogradova, IV | 1 |
Kiseleva, NS | 1 |
Ankhimiuk, ON | 1 |
Fröhling, PT | 1 |
Krupki, F | 1 |
Kokot, F | 1 |
Vetter, K | 1 |
Kaschube, I | 1 |
Lindenau, K | 1 |
Rademaker, M | 1 |
Corrie, J | 1 |
Lindsay, BA | 1 |
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Lawal, SO | 1 |
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Falase, AO | 2 |
Petrie, JC | 2 |
Robb, OJ | 1 |
Trafford, J | 1 |
Burgess, J | 1 |
Richardson, PJ | 1 |
Fairhurst, G | 1 |
Vandenburg, MJ | 1 |
Cooper, WD | 1 |
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Vandongen, R | 1 |
Armstrong, BK | 1 |
Grichois, ML | 1 |
de Mendonça, M | 1 |
Wauquier, I | 1 |
Pernollet, MG | 1 |
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Mihatsch, MJ | 1 |
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Herchuelz, A | 1 |
Kuijpers, MH | 1 |
Provoost, AP | 1 |
de Jong, W | 1 |
Nimmo, GR | 1 |
Lawson, AA | 1 |
Backhouse, CI | 1 |
Rowley-Jones, D | 1 |
Spencer-Mills, L | 1 |
Zoccali, C | 1 |
Hutcheson, MJ | 1 |
Barnett, P | 1 |
Hasslacher, C | 1 |
Prichard, BN | 1 |
Brogden, RN | 1 |
Murphy, VA | 1 |
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Zicha, J | 1 |
Butler, A | 1 |
Hunt, D | 1 |
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Meywald, W | 1 |
Maass, L | 1 |
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Rangoonwala, B | 1 |
Clark, AD | 1 |
Sevitt, LH | 1 |
Hawkins, DF | 1 |
Vaughan, ED | 1 |
Gillenwater, JY | 1 |
Claude, JR | 1 |
Fairman, MJ | 2 |
Hamilton, M | 3 |
Harpur, JE | 3 |
George, CF | 1 |
Breckenridge, AM | 1 |
Jackson, WB | 1 |
Soballa, G | 2 |
Richards, P | 1 |
Ishii, M | 3 |
Duke, M | 2 |
Goss, LZ | 1 |
Rosa, RM | 1 |
O'Brien, WM | 1 |
Ayers, CR | 1 |
Wood, JE | 1 |
Rosenoer, VM | 1 |
Cohen, SL | 1 |
Percival, A | 1 |
Werning, C | 1 |
Stiel, W | 1 |
Schweikert, HU | 1 |
Stiel, D | 1 |
Vetter, W | 1 |
Siegenthaler, W | 1 |
Genest, J | 1 |
Boucher, R | 1 |
Kuchel, O | 1 |
Nowaczynski, W | 1 |
Kremer, D | 2 |
Hayduk, K | 1 |
Riegger, G | 1 |
Krause, DK | 1 |
Kaufmann, W | 1 |
Johnson, B | 1 |
Bye, C | 1 |
Labrooy, J | 1 |
Munro-Faure, D | 1 |
Slack, J | 1 |
Kennedy, AC | 1 |
Burton, JA | 1 |
Allison, ME | 1 |
Hawthorne, VM | 1 |
Greaves, DA | 1 |
Cappin, JM | 1 |
Klumpp, F | 1 |
Klaus, D | 1 |
Lemke, R | 1 |
Trieschmann, W | 1 |
Zehner, J | 1 |
Zöfel, P | 1 |
Ahnefeld-Olbertz, S | 1 |
Rudolfsky, G | 1 |
Schultis, K | 1 |
Singh, MM | 1 |
Macgillivray, I | 1 |
Mahaffy, RG | 1 |
Hubert, C | 1 |
Demanet, JC | 1 |
Degaute, JP | 1 |
Fichefet, JP | 1 |
Paduart, P | 1 |
Pohl, JE | 2 |
Jamison, RL | 1 |
Hall, CL | 1 |
Pejhan, N | 1 |
Thomson, RW | 1 |
Dawson-Edwards, P | 1 |
Barnes, AD | 1 |
Robinson, BH | 1 |
Meynell, MJ | 1 |
Blainey, JD | 1 |
Cameron, JS | 1 |
Davies, DR | 1 |
Tighe, JR | 1 |
Jones, NF | 1 |
Brown, GW | 1 |
Orme, ML | 1 |
Vetter, G | 1 |
Mazo, EB | 1 |
Logan, DA | 1 |
Howie, HB | 1 |
Crawford, J | 1 |
Lageder, H | 1 |
Hartl, O | 1 |
Irsigler, K | 1 |
Chazov, EI | 1 |
Smirnov, VN | 1 |
Mazaev, AV | 1 |
Asafov, GB | 1 |
Degtiar', VG | 1 |
Safar, M | 1 |
Baglin, A | 1 |
Sobel, A | 1 |
Merceron, R | 1 |
Milliez, P | 1 |
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Menter, MA | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Assessment of the Incremental Haemodialysis Security and Effectiveness in Incident Patients[NCT03239808] | 152 participants (Actual) | Interventional | 2018-03-14 | Active, not recruiting | |||
Effect Of Dialysate Flow Rate On Mass Transfer Coefficient - Area (KoA) In Dialyzers With Different Membrane Packing Densities[NCT00636077] | 12 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
The Role of Orexin in Human Panic Disorder[NCT02593682] | Phase 4 | 3 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
An Open-label Study of the Efficacy and Safety of CORLUX (Mifepristone) in the Treatment of the Signs and Symptoms of Endogenous Cushing's Syndrome[NCT00569582] | Phase 3 | 50 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
Mifepristone Treatment for Breast Cancer Patients Expressing Levels of Progesterone Receptor Isoform A (PRA) Higher Than Those of Isoform B (PRB): Neoadjuvant Therapy.[NCT02651844] | 20 participants (Actual) | Interventional | 2016-04-30 | Completed | |||
Treatment of Pituitary Cushing Disease With a Selective CDK Inhibitor, R-roscovitine[NCT02160730] | Phase 2 | 4 participants (Actual) | Interventional | 2014-05-31 | Terminated (stopped due to NIH grant ended.) | ||
Using of the Skin as a Third Spare Kidney for Patients With Chronic Renal Failure[NCT03810989] | 86 participants (Anticipated) | Interventional | 2019-06-01 | Not yet recruiting | |||
Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women With Preeclampsia[NCT04298034] | Phase 3 | 300 participants (Anticipated) | Interventional | 2020-07-17 | Recruiting | ||
[NCT00005270] | 0 participants | Observational | 1995-09-30 | Completed | |||
A Multinational Prospective Study on the Duration of Steroid Therapy in Steroid Sensitive Nephrotic Syndrome[NCT03878914] | Phase 4 | 34 participants (Actual) | Interventional | 2019-08-06 | Terminated (stopped due to The study was terminated at all but one site because of the pandemic) | ||
Lung Water By Ultra-Sound Guided Treatment To Prevent Death and Cardiovascular Complications in High Risk End Stage Renal Disease Patients With Cardiomyopathy (Lust Study)[NCT02310061] | 383 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | KoA for b2-microglobulin (mL/min) (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 27 | 28 | 31 |
F200NR | 27 | 25 | 21 |
HD-C4 Big | 65 | 62 | 64 |
HD-C4 Small | 61 | 57 | 56 |
(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | KoA for Phosphorus (mL/min) (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 434 | 450 | 458 |
F200NR | 504 | 491 | 560 |
HD-C4 Big | 434 | 435 | 520 |
HD-C4 Small | 334 | 422 | 415 |
KoA is a constant that describes the efficiency of a dialyzer in removing urea. KoA is determined by surface area of the membrane, the thickness of the membrane and pore size. (NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | KoA for urea (mL/min) (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 770 | 738 | 809 |
F200NR | 798 | 890 | 817 |
HD-C4 Big | 844 | 898 | 922 |
HD-C4 Small | 763 | 748 | 761 |
(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | whole blood clearance B2-microglobulin (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 87 | 86 | 78 |
F200NR | 72 | 65 | 75 |
HD-C4 Big | 106 | 129 | 118 |
HD-C4 Small | 119 | 118 | 121 |
(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | whole blood phosphorus clearance mL/min (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 247 | 260 | 272 |
F200NR | 249 | 265 | 281 |
HD-C4 Big | 255 | 269 | 286 |
HD-C4 Small | 252 | 261 | 273 |
(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)
Intervention | Whole blood urea clearance (mL/min) (Mean) | ||
---|---|---|---|
350 mL/min Dialysate Flow Rate | 500 mL/min Dialysate Flow Rate | 800 mL/min Dialysate Flow Rate | |
F160NR | 271 | 293 | 313 |
F200NR | 274 | 313 | 327 |
HD-C4 Big | 279 | 315 | 340 |
HD-C4 Small | 270 | 295 | 320 |
Responder is defined as subject with a decrease greater than or equal to 5mm Hg in diastolic blood pressure from baseline to week 24 or last visit. (NCT00569582)
Timeframe: Baseline to Week 24
Intervention | participants (Number) |
---|---|
Mifepristone | 8 |
Responder is defined as subject with a decrease greater than or equal to 25% in area under the curve for glucose on 2-hour oral glucose test from baseline to week 24 or last visit, for Cushing's patients with type-2 diabetes mellitus/impaired glucose tolerance. (NCT00569582)
Timeframe: Baseline to Week 24
Intervention | participants (Number) |
---|---|
Mifepristone | 15 |
The number of participants that achieved a urinary free cortisol level above the upper limit of the normal range but reduced by ≥50% from baseline at week 4. (NCT02160730)
Timeframe: Baseline, Week 4
Intervention | Participants (Count of Participants) |
---|---|
R-roscovitine | 2 |
A visible change in tumor size as determined by the investigator after reviewing MRI reports between baseline and 4 weeks of treatment. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | Participants (Count of Participants) |
---|---|
R-roscovitine | 0 |
"To evaluate the efficacy of R-roscovitine 400 mg oral administration twice daily for 4 days every week for total of 4 weeks on normalizing 24 hour urinary free cortisol (24 h UFC) levels in CD patients. Normalizing is defined as having urine free cortisol levels within the normal range for that lab value." (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | Participants (Count of Participants) |
---|---|
R-roscovitine | 0 |
The number of participants that experience an adverse event between baseline and study end likely related to study drug as a measure of safety and tolerability. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | Participants (Count of Participants) |
---|---|
R-roscovitine | 2 |
Change in typical Cushing's syndrome clinical signs and symptoms defined by mean weight at baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | lbs (Mean) | |
---|---|---|
Baseline | 4 Weeks | |
R-roscovitine | 217 | 217.4 |
Mean diastolic blood pressure between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | mmHg (Mean) | |
---|---|---|
Baseline | 4 Weeks | |
R-roscovitine | 76.5 | 71 |
HbA1c levels are measured at baseline and at study end, these are averaged across all subjects. (NCT02160730)
Timeframe: Baseline, 4 Weeks
Intervention | Percentage (Mean) | |
---|---|---|
Baseline | Study End-4 weeks | |
R-roscovitine | 6.9 | 7 |
Mean change in systolic blood pressure between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | mmHg (Mean) | |
---|---|---|
Baseline | 4 weeks | |
R-roscovitine | 150.3 | 128.3 |
Mean serum cortisol values at baseline and 4 weeks (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | mg/dL (Mean) | |
---|---|---|
Baseline | 4 Weeks | |
R-roscovitine | 25.6 | 27.1 |
Mean change between baseline and week 4 of fasting blood glucose levels. (NCT02160730)
Timeframe: Baseline, 4 Weeks
Intervention | g/dL (Mean) | |
---|---|---|
Baseline | 4 weeks | |
R-roscovitine | 121.4 | 104.3 |
Mean change in Plasma ACTH between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
Intervention | pg/mL (Mean) | |
---|---|---|
Baseline | 4 weeks | |
R-roscovitine | 79.3 | 79.9 |
18 reviews available for urea and Blood Pressure, High
Article | Year |
---|---|
[Multidisciplinary management of a typical case of acute kidney failure in the course of COVID-19 infection].
Topics: Acute Kidney Injury; Aged; Antihypertensive Agents; Antiviral Agents; Betacoronavirus; Coronavirus I | 2020 |
Preservation of residual kidney function in hemodialysis patients: reviving an old concept.
Topics: Aminoglycosides; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
RADIOISOTOPIC RENAL FUNCTION STUDIES AND SURGICAL FINDINGS IN 102 HYPERTENSIVE PATIENTS.
Topics: Contrast Media; Humans; Hypertension; Hypertension, Renal; Iodine Isotopes; Iodohippuric Acid; Iodop | 1964 |
USE OF DIFFERENTIAL RENAL FUNCTION STUDIES IN THE DIAGNOSIS OF RENOVASCULAR HYPERTENSION.
Topics: Blood Vessel Prosthesis; Creatine; Creatinine; Humans; Hypertension; Hypertension, Renal; Hypertensi | 1964 |
URETERAL CATHETERIZATION MEASUREMENTS IN RENAL HYPERTENSION.
Topics: Angiography; Creatine; Creatinine; Cystoscopy; Humans; Hypertension; Hypertension, Renal; Insulin; I | 1964 |
[Short time hemodialysis].
Topics: Blood Urea Nitrogen; Humans; Hypertension; Hypotension; Renal Dialysis; Time Factors; Ultrafiltratio | 2004 |
Fournier's gangrene: experience with 25 patients and use of Fournier's gangrene severity index score.
Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Anti-Bacterial Agents; Blood Proteins; Combine | 2004 |
Treatment time and ultrafiltration rate are more important in dialysis prescription than small molecule clearance.
Topics: Body Composition; Humans; Hypertension; Hypotension; Metabolic Clearance Rate; Renal Dialysis; Time | 2007 |
Role of urotensin II and its receptor in health and disease.
Topics: Animals; Calcium; Cricetinae; Cricetulus; Diabetes Mellitus; Heart Failure; Humans; Hypertension; In | 2007 |
[Blood pressure-regulating factor vasopressin].
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Body Water; Cyclic AMP; Humans; Hypertension; | 1997 |
[Factors in the progression of renal insufficiency during the 2 years preceding the use of dialysis].
Topics: Acidosis; Aged; Anemia; Antihypertensive Agents; Blood Proteins; Combined Modality Therapy; Comorbid | 1999 |
Daily hemodialysis: is it a complex therapy with unproven benefits?
Topics: Anemia; Appointments and Schedules; Erythropoietin; Humans; Hypertension; Kidney Failure, Chronic; K | 2001 |
Metabolic profile of indapamide sustained-release in patients with hypertension: data from three randomised double-blind studies.
Topics: Adolescent; Adult; Aged; Blood Glucose; Creatinine; Delayed-Action Preparations; Diuretics; Double-B | 2001 |
The morphological approach to the study of normal and abnormal brain permeability.
Topics: Animals; Axonal Transport; Blood Proteins; Blood-Brain Barrier; Brain; Brain Neoplasms; Capillaries; | 1976 |
Assessment of renal functions in hypertensive pregnancies.
Topics: Acute Kidney Injury; Female; Fetal Death; Humans; Hypertension; Kidney; Kidney Glomerulus; Kidney Tu | 1977 |
Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.
Topics: Animals; Body Weight; Diuretics; Edema; Electrolytes; Half-Life; Humans; Hypertension; Intestinal Ab | 1985 |
[Changes in fat granules of interstitial cell of the renal papilla in hypertensive animals].
Topics: Animals; Blood Pressure; Cytoplasmic Granules; Histocytochemistry; Hypertension; Hypertension, Renal | 1971 |
Intrarenal heterogeneity. The case for two functionally dissimilar populations of nephrons in the mammalian kidney.
Topics: Animals; Ferrocyanides; Glomerular Filtration Rate; Humans; Hypertension; Inulin; Juxtaglomerular Ap | 1973 |
51 trials available for urea and Blood Pressure, High
Article | Year |
---|---|
Effects of Olive Leaf Extract on Metabolic Response, Liver and Kidney Functions and Inflammatory Biomarkers in Hypertensive Patients.
Topics: Adult; Aged; Albumins; Biomarkers; Body Mass Index; Body Weight; Creatinine; Double-Blind Method; Fe | 2019 |
Effects of probiotic therapy on cardio-metabolic parameters and autonomic modulation in hypertensive women: a randomized, triple-blind, placebo-controlled trial.
Topics: Adult; Anthropometry; Bifidobacterium; Bifidobacterium animalis; Biomarkers; Blood Glucose; Blood Pr | 2020 |
Changes in selected metabolic parameters in patients over 65 receiving hydrochlorothiazide plus amiloride, atenolol or placebo in the MRC elderly trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Age Factors; Aged; Amiloride; Antihypertensive Agents; Ateno | 2016 |
Effects of landiolol, a short-acting beta-1 blocker, on hemodynamic variables during emergence from anesthesia and tracheal extubation in elderly patients with and without hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia Recovery Period; Blood Pressure; Electroencephalograph | 2009 |
Effect of the urotensin receptor antagonist palosuran in hypertensive patients with type 2 diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Creatinine; Cross-Over Studies; D | 2010 |
Landiolol attenuates cardiovascular response at induction of general anesthesia for cesarean delivery.
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, General; Anesthesia, Obstetrical; Blood Pressure; Ce | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Composition; Body Weight; Cushin | 2012 |
Stimulated sweating as a therapy to reduce interdialytic weight gain and improve potassium balance in chronic hemodialysis patients: a pilot study.
Topics: Adult; Aged; Female; Hemofiltration; Humans; Hyperkalemia; Hypertension; Hyperthermia, Induced; Male | 2013 |
Comparative effect of lisinopril and lacidipine on urinary albumin excretion in patients with type 11 diabetic nephropathy.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood | 2002 |
Combination of pentoxifylline with angiotensin converting enzyme inhibitors produces an additional reduction in microalbuminuria in hypertensive type 2 diabetic patients.
Topics: Aged; Albumins; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Pressure; C | 2003 |
Pharmacodynamics and pharmacokinetics of the urotensin II receptor antagonist palosuran in macroalbuminuric, diabetic patients.
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors | 2006 |
Baseline predictors of renal disease progression in the African American Study of Hypertension and Kidney Disease.
Topics: Adolescent; Adult; Aged; Black or African American; Creatinine; Disease Progression; Female; Glomeru | 2006 |
The hemodynamic effects of landiolol, an ultra-short-acting beta1-selective blocker, on endotracheal intubation in patients with and without hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arthroplasty, Replacement, Hip; Blood Pressure; Female; Fe | 2007 |
Placebo-controlled trial of a combination of bemetizide and triamterene ('Hypertane') in mild or moderate hypertension.
Topics: Adult; Aged; Benzothiadiazines; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Comb | 1983 |
Multicentre controlled trial of tienilic acid in hyperuricaemic, hypertensive subjects, with intensive monitoring of liver function.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Creatinine; Electrolytes; Female; Glycolates; Hu | 1983 |
Indapamide in hypertension: results of a French multi-centre study in ambulant subjects.
Topics: Aged; Ambulatory Care; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Diuretics; Heart Rat | 1983 |
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension].
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Fem | 1984 |
Lack of effect of beta-blocker on flat dose response to thiazide in hypertension: efficacy of low dose thiazide combined with beta-blocker.
Topics: Acebutolol; Adult; Body Weight; Chlorides; Clinical Trials as Topic; Dose-Response Relationship, Dru | 1983 |
Effect on intra-arterial blood pressure of slow release metoprolol combined with placebo or chlorthalidone.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Delayed-Action Preparations; | 1983 |
Indapamide and bendrofluazide: a comparison in the management of essential hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Diuretics; Electrolytes; Female; Humans; Hy | 1981 |
Chlorthalidone in mild hypertension - dose response relationship.
Topics: Adult; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Female; Humans; Hypertensio | 1981 |
The effect of rest and ambulation on plasma urea and urate levels in pregnant women with proteinuric hypertension.
Topics: Bed Rest; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinu | 1980 |
The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension.
Topics: Amlodipine; Blood Pressure; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hyperte | 1995 |
Factors affecting nPCR in hemodialysed patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Urea Nitrogen; Diabetes Mellitus; Female; Follow-U | 1995 |
[Evaluation of fetal condition in pregnancy complicated by hypertension--biochemical assessment of amniotic fluid. I. Protein and lipid components and kidney maturation].
Topics: Adult; Albumins; Amniotic Fluid; Cholesterol; Creatinine; Female; Humans; Hypertension; Hypertension | 1996 |
Predilution haemofiltration--the Second Sardinian Multicentre Study: comparisons between haemofiltration and haemodialysis during identical Kt/V and session times in a long-term cross-over study.
Topics: Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Depr | 2001 |
Dietary protein and soluble fiber reduce ambulatory blood pressure in treated hypertensives.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Diastole; Dietary Fiber; Dietary | 2001 |
Antihypertensive therapy with timolol and alpha-methyldopa. A double-blind trial in patients with moderately severe hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; | 1976 |
Biochemical and haematological changes induced by tienilic acid combined with propranolol in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Sedimentation; Clinical Trials as Topic; Creatinine; Diuretics; D | 1979 |
Prazosin in the therapy of uncontrolled hypertension.
Topics: Adult; Aged; Clinical Trials as Topic; Creatinine; Female; Humans; Hypertension; Hypotension, Orthos | 1977 |
Spironolactone in essential hypertension: evidence against its effect through mineralocorticoid antagonism.
Topics: Adult; Bicarbonates; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; M | 1976 |
The effect of spironolactone (Aldactone) and methyldopa in low and normal renin hypertension.
Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Depression, Chemical; Drug Thera | 1975 |
Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients.
Topics: Aldosterone; Blood Pressure; Bromocriptine; Creatinine; Dopamine Agents; Female; Heart Rate; Hemodyn | 1992 |
What are the most important factors in the progression of renal failure?
Topics: Acidosis; Blood Pressure; Humans; Hypercalcemia; Hyperparathyroidism; Hypertension; Kidney Failure, | 1989 |
Enalapril in moderate to severe hypertension: a comparison with atenolol.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Creatinine; Drug Evaluation; Drug Therapy, Combin | 1986 |
Vegetarian diet in mild hypertension: a randomised controlled trial.
Topics: Adult; Calcium, Dietary; Clinical Trials as Topic; Diet, Vegetarian; Dietary Fats, Unsaturated; Diet | 1986 |
Torasemide, a new potent diuretic. Double-blind comparison with furosemide.
Topics: Aged; Aged, 80 and over; Body Weight; Clinical Trials as Topic; Creatinine; Diuretics; Double-Blind | 1986 |
Hydrochlorothiazide and triamterene with sustained-release oxprenolol in the treatment of hypertension.
Topics: Aged; Creatinine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidn | 1986 |
Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Condiments; Female; Heart Rate; Humans; Hyperten | 1985 |
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.
Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; H | 1973 |
The effects of long term administration of dopamine on renal function in hypertensive patients.
Topics: Adult; Aged; Aminohippuric Acids; Blood Pressure; Body Weight; Clinical Trials as Topic; Dopamine; F | 1973 |
[Clinical testing of a new potassium-saving diuretic for the treatment of hypertension].
Topics: Aged; Amiloride; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Diuretics; Drug | 1973 |
[Namestin (Clonidine), 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride in the treatment of essential hypertension (author's transl)].
Topics: Blood Pressure; Chlorides; Clinical Trials as Topic; Clonidine; Creatinine; Drug Evaluation; Fatigue | 1974 |
Methyldopa combined with prindolol in the treatment of severe hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Furosem | 1974 |
Ethacrynic acid alone and in combination with methyldopa in the management of mild hypertension. A report of 23 patients.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diarrhea; Drug Synergism; Ethacrynic Acid; Fe | 1970 |
A comparison of the effects of hydrochlorothiazide and of frusemide in the treatment of hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Blood Proteins; Carbon Dioxide; Clinical Trials as Topic; Female; Furos | 1971 |
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels.
Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans; | 1972 |
Effect of triamterene on elevated arterial pressure.
Topics: Adult; Blood Chemical Analysis; Chlorthalidone; Clinical Trials as Topic; Creatine; Female; Humans; | 1965 |
Potassium-sparing effects of triamterene in the treatment of hypertension.
Topics: Adult; Aged; Blood Gas Analysis; Blood Glucose; Chlorides; Chlorothiazide; Clinical Trials as Topic; | 1966 |
[Report on the clinical testing of the Sembrina--Saltucin. Drug combination for the treatment of hypertension].
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Creatinine; Diuretics; Humans; Hypertension; Hypertensio | 1969 |
Amiloride hydrochloride in hypertensive patients.
Topics: Bicarbonates; Blood Pressure; Chlorides; Depression, Chemical; Diuretics; Drug Synergism; Guanidines | 1968 |
312 other studies available for urea and Blood Pressure, High
Article | Year |
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Morphology and cyclooxygenase-2 and renin expression in the kidney of young spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Cyclooxygenase 2; Hypertension; Kidney; Rats; R | 2022 |
Anti-hypertensive effects of
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Hypertension, Renovascular; Kidney; | 2022 |
Development of semi-quantitative urinary sodium test strip.
Topics: Humans; Hypertension; Sodium; Sodium Chloride; Sodium Chloride, Dietary; Urea | 2023 |
Soluble epoxide hydrolase inhibitor, t-AUCB, improves salivary gland function by ameliorating endothelial injury.
Topics: AMP-Activated Protein Kinases; Animals; Benzoates; Endothelial Cells; Endothelium; Enzyme Inhibitors | 2022 |
Nomogram model for predicting early onset of chronic kidney disease using color Doppler region of interest technique.
Topics: Albumins; Diabetes Mellitus; Humans; Hypertension; Nitrogen; Nomograms; Renal Insufficiency, Chronic | 2022 |
Evaluating the risk of hypertension in residents in primary care in Shanghai, China with machine learning algorithms.
Topics: Adult; Aged; Algorithms; China; Cholesterol; Creatinine; Glucose; Humans; Hypertension; Lipoproteins | 2022 |
Metabolomic Profile and Its Correlation with the Plasmatic Levels of Losartan, EXP3174 and Blood Pressure Control in Hypertensive and Chronic Kidney Disease Patients.
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Losartan; Renal Insufficiency, Chroni | 2023 |
Serum Creatinine and Occurrence and Severity of Coronary Artery Disease.
Topics: Adult; Aged; Apolipoprotein A-I; Biomarkers; Case-Control Studies; Cholesterol, HDL; Coronary Diseas | 2019 |
Optimizing heart failure management: anticoagulation, diuretic withdrawal, iron substitution, and novel inotropes.
Topics: Acute Disease; Anemia, Iron-Deficiency; Anticoagulants; Cardiotonic Agents; Case-Control Studies; Di | 2019 |
Norvaline Reduces Blood Pressure and Induces Diuresis in Rats with Inherited Stress-Induced Arterial Hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Creatinine; Disease Models, Animal; Diuresis; Hype | 2020 |
Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease.
Topics: Actins; Animals; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Ventricles; Hypertension; Kidney; M | 2020 |
Hyperbaric Oxygen Preconditioning Upregulates Heme OxyGenase-1 and Anti-Apoptotic Bcl-2 Protein Expression in Spontaneously Hypertensive Rats with Induced Postischemic Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Heme Oxygenase (Decyclizing); Huma | 2021 |
The Cox model of predicting mortality among melioidosis patients in Northern Malaysia: A retrospective study.
Topics: Adult; Aged; Anti-Bacterial Agents; Burkholderia pseudomallei; Diabetes Mellitus; Female; Hospital M | 2021 |
Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.
Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Neoplasms; Comorbidity; Creat | 2018 |
Discrimination model applied to urinalysis of patients with diabetes and hypertension aiming at diagnosis of chronic kidney disease by Raman spectroscopy.
Topics: Aged; Biomarkers; Creatinine; Diabetes Mellitus; Female; Glucose; Humans; Hypertension; Male; Middle | 2017 |
Cerebrovascular recovery after stroke with individual and combined losartan and captopril treatment of SHRsp.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2017 |
Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms.
Topics: Animals; Blood Pressure; Creatinine; Diastole; Ginkgo biloba; Glutathione; Hypercholesterolemia; Hyp | 2017 |
Tempol, a superoxide dismutase-mimetic drug, prevents chronic ischemic renal injury in two-kidney, one-clip hypertensive rats.
Topics: Animals; Antioxidants; Biomimetic Materials; Blood Pressure; Caspase 3; Chronic Disease; Creatinine; | 2018 |
Long-term exercise restores hydrogen sulfide in the kidney and contributes to exercise benefits in 5/6 nephrectomized rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Hydrogen Sulfide; Hypertension; Kidney; Male; Malondialdeh | 2019 |
Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient.
Topics: Diabetes Mellitus, Type 2; Diuresis; Electrolytes; Glucocorticoids; Humans; Hypernatremia; Hypertens | 2013 |
Relationship between serum nitric oxide and sialic acid in coexisted diabetes, hypertension and nephropathy.
Topics: Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus; Diabetic Nephropathies; Fasting; Femal | 2013 |
Twenty-four hour urinary urea excretion and 9-year risk of hypertension: the PREVEND study.
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Diet; Female; Humans; Hypertension; Kidney Failure, Ch | 2013 |
Correlating the amount of urea, creatinine, and glucose in urine from patients with diabetes mellitus and hypertension with the risk of developing renal lesions by means of Raman spectroscopy and principal component analysis.
Topics: Biomarkers; Brazil; Causality; Comorbidity; Creatinine; Diabetic Nephropathies; Diagnosis, Computer- | 2013 |
Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension.
Topics: Alkanes; Animals; Antihypertensive Agents; Blood Pressure; Epoxide Hydrolases; Humans; Hypertension; | 2013 |
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Blood P | 2014 |
[Successful anesthetic management of a patient with giant pheochromocytoma using high-dose landiolol hydrochloride].
Topics: Adrenal Gland Neoplasms; Analgesia, Epidural; Anesthesia, General; Arrhythmias, Cardiac; Catecholami | 2014 |
Thiazide-induced hyponatraemia is associated with increased water intake and impaired urea-mediated water excretion at low plasma antidiuretic hormone and urine aquaporin-2.
Topics: Aged; Aged, 80 and over; Aquaporin 2; Drinking; Electrolytes; Female; Humans; Hydrochlorothiazide; H | 2015 |
[Serum uric acid levels and risk of developing preeclampsia].
Topics: Adult; Birth Weight; Creatinine; Early Diagnosis; Female; Humans; Hypertension; Infant, Low Birth We | 2014 |
[Orthostatic reactions in prognosis of the risks of arterial hypertension as a component of metabolic syndrome].
Topics: Acute Coronary Syndrome; Aged; Blood Glucose; Cholesterol; Female; Humans; Hypertension; Hypotension | 2014 |
Comparative assessment of neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C as early biomarkers for early detection of renal failure in patients with hypertension.
Topics: Acute-Phase Proteins; Biomarkers; Blood Pressure; C-Reactive Protein; Creatinine; Cross-Sectional St | 2015 |
The H.U.G.E. Formula (Hematocrit, Urea, Sex) for Screening Chronic Kidney Disease (CKD) in an Age-Stratified General Population.
Topics: Adult; Age Distribution; Age Factors; Aged; Aging; Albuminuria; Anthropometry; Cardiovascular Diseas | 2015 |
Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells.
Topics: Angiotensin II; Animals; Antioxidants; Chemokine CCL2; Cofilin 1; Creatinine; Cytoskeleton; Epitheli | 2015 |
Inhibition of NHE3-mediated Sodium Absorption in the Gut Reduced Cardiac End-organ Damage Without Deteriorating Renal Function in Obese Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Genetic Predisposition to | 2016 |
Association Between Protein Intake and Mortality in Hypertensive Patients Without Chronic Kidney Disease in the OLD-HTA Cohort.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Determination; Cardiovascular Diseases; Cause o | 2016 |
Pharmacogenetic effects of angiotensin-converting enzyme inhibitors over age-related urea and creatinine variations in patients with dementia due to Alzheimer disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Angiotensin-Converting Enzyme Inhi | 2016 |
Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Female; Gout; Humans; Hypertension; Interleukin-33; Kidn | 2016 |
Prognostic indices among hypertensive heart failure patients in Nigeria: the roles of 24-hour Holter electrocardiography and 6-minute walk test.
Topics: Aged; Atrial Fibrillation; Biomarkers; Chi-Square Distribution; Echocardiography, Doppler; Electroca | 2017 |
[Perioperative and postoperative management of two patients with uncontrolled hyperthyroidism using short acting beta blocker, landiolol].
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia; Antithyroid Agents; Fracture Fixation, Internal; Hum | 2008 |
Prevalence of hypertension among Iranian hemodialysis patients and associated risk factors: a nationwide multicenter study.
Topics: Aged; Female; Humans; Hypertension; Iran; Kidney Failure, Chronic; Male; Middle Aged; Models, Statis | 2008 |
Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities.
Topics: Anti-Inflammatory Agents; Benzoates; Chemistry, Pharmaceutical; Drug Design; Epoxide Hydrolases; Hum | 2009 |
Baseline characteristics of participants in the Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anthropometry; Blood Glucose; Cholesterol, HDL; Comorbidi | 2009 |
[General anesthesia for cesarean section in a patient with moyamoya disease].
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anti-Arrhythmia Agents; Cesarean Section; Emerg | 2009 |
Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile.
Topics: Analysis of Variance; Animals; Arginase; Arginine; Baroreflex; Blood Flow Velocity; Blood Pressure D | 2009 |
Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension.
Topics: Albuminuria; Animals; Benzoates; Blood Pressure; Chemokine CCL2; Desoxycorticosterone; Disease Model | 2009 |
Platelet aggregation in arterial hypertension: is there a nitric oxide-urea connection?
Topics: Adult; Arginase; Arginine; Blood Platelets; C-Reactive Protein; Collagen; Female; Humans; Hypertensi | 2010 |
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Blood Pressure; Epoxide Hydrolases; Humans; Hypertension; Mode | 2009 |
[Risk factors for renal dysfunction after total hip arthroplasty].
Topics: Acute Kidney Injury; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Ag | 2009 |
Relationship between plasma uridine and urinary urea excretion.
Topics: Adult; Creatinine; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gout; Homeostasis; H | 2010 |
Continuous hypertension and tachycardia after resection of a hemangioblastoma behind the dorsal medulla oblongata: relationship to sympathetic overactivity at the neurogenic vasomotor center.
Topics: Adrenergic beta-Antagonists; Autonomic Nervous System Diseases; Baroreflex; Brain Stem Neoplasms; Ca | 2010 |
No juvenile arterial hypertension in sheep multiples despite reduced nephron numbers.
Topics: Age Factors; Animals; Animals, Newborn; Biomarkers; Blood Pressure; Body Weight; Creatinine; Disease | 2010 |
Normal growth and intravascular volume status with good metabolic control during peritoneal dialysis in infancy.
Topics: Anuria; Child; Creatinine; Female; Humans; Hypertension; Male; Peritoneal Dialysis; Phosphorus; Pros | 2010 |
Assessment of renal vascular resistance and blood pressure in dogs and cats with renal disease.
Topics: Animals; Blood Pressure; Case-Control Studies; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; E | 2010 |
[Pregnancy and advanced chronic kidney disease].
Topics: Ductus Arteriosus, Patent; Epilepsy; Female; Fetal Growth Retardation; Humans; Hyaline Membrane Dise | 2010 |
Effect of increasing dialysate flow rate on diffusive mass transfer of urea, phosphate and beta2-microglobulin during clinical haemodialysis.
Topics: beta 2-Microglobulin; Cross-Over Studies; Dialysis Solutions; Female; Glomerulonephritis; Humans; Hy | 2010 |
Role of 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of vascular function in a model of hypertension and endothelial dysfunction.
Topics: Amidines; Animals; Arachidonic Acids; Blood Pressure; Carbachol; Cardiovascular Physiological Phenom | 2010 |
Ambulatory blood pressure monitoring and renal functions in term small-for-gestational age children.
Topics: Acetylglucosaminidase; Albuminuria; beta 2-Microglobulin; Birth Weight; Blood Pressure; Blood Pressu | 2011 |
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Benzoates | 2011 |
Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.
Topics: Adamantane; Administration, Oral; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2011 |
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.
Topics: Adamantane; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; D | 2011 |
Adequacy of control of preoperative hypertension can affect landiolol-induced hemodynamic changes in elderly patients during emergence from anesthesia.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia; Blood Pressure; Dose-Response Relationship, Drug; Hea | 2011 |
Prevention of systemic and regional haemodynamic alterations, hypercreatininemia, hyperuremia and hyperphosphatemia by losartan in hypertension with acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Animals; Creatinine; Hemodynamics; Hyp | 2011 |
Inhibition of smooth muscle myosin as a novel therapeutic target for hypertension.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Dogs; Female; Hemodyna | 2011 |
Serum cystatin C and microalbuminuria in the detection of vascular and renal damage in early stages.
Topics: Adult; Aged; Aged, 80 and over; Aging; Albuminuria; Biomarkers; Cardiovascular Diseases; Chronic Dis | 2011 |
Glycemic control, dyslipidemia and endothelial dysfunction in coexisted diabetes, hypertension and nephropathy.
Topics: Albuminuria; Blood Glucose; Cholesterol; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, T | 2012 |
Short-term ACE inhibition confers long-term protection against target organ damage.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Proliferation; Creatinine; D | 2012 |
Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzoates; Blood Pressure; C | 2012 |
Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.
Topics: Animals; Anxiety; Benzoxazoles; Bradycardia; Disease Models, Animal; Hypercapnia; Hypertension; Intr | 2012 |
Dietary protein, blood pressure and renal function in renal transplant recipients.
Topics: Adult; Aged; Albuminuria; Blood Pressure; Cohort Studies; Creatinine; Cross-Sectional Studies; Dieta | 2013 |
Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Topics: Animals; Antihypertensive Agents; Benzoates; Blood Pressure; Down-Regulation; Epoxide Hydrolases; Fe | 2013 |
Decreased expression of arginase II in the kidneys of Dahl salt-sensitive rats.
Topics: Animals; Arginase; Arginine; Hypertension; Kidney; Male; Nitric Oxide; Rats; Rats, Inbred Dahl; RNA, | 2002 |
Kidney specificity of rat chromosome 1 blood pressure quantitative trait locus region.
Topics: Animals; Animals, Congenic; Blood Pressure; Body Weight; Chromosomes; Creatinine; Genetic Predisposi | 2002 |
Salt supresses baseline muscle sympathetic nerve activity in salt-sensitive and salt-resistant hypertensives.
Topics: Adult; Antihypertensive Agents; Baroreflex; Biomarkers; Blood Pressure; Body Mass Index; Body Weight | 2002 |
Secondary hyperparathyroidism in chronic hemodialysis patients: prevalence and race.
Topics: Adult; Age Factors; Calcium Phosphates; Diabetes Complications; Diabetes Mellitus; Erythropoietin; F | 2003 |
Risk factors for hospital death of patients with end-stage renal disease without previous diagnosis of severe chronic renal failure arriving in an emergency situation at the hospital.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Bicarbonates; Biomarkers; Brazil; Child; Cr | 2003 |
[Treatment of hypertonia].
Topics: Hypertension; Methenamine; Muscle Hypertonia; Papaverine; Urea | 1953 |
[Experimental results in the treatment of hypertension with urea].
Topics: Humans; Hypertension; Urea | 1953 |
ALPHA-METHYL DOPA FOR THE TREATMENT OF HYPERTENSION: CLINICAL AND PHARMACODYNAMIC STUDIES.
Topics: Alkaline Phosphatase; Antihypertensive Agents; Bilirubin; Blood Cell Count; Blood Glucose; Blood Pre | 1963 |
THE EFFECTS OF PARTIAL NEPHRECTOMY ON THE BLOOD PRESSURE AND RENAL FUNCTION OF HYPERTENSIVE DOGS.
Topics: Angiography; Animals; Blood Chemical Analysis; Blood Pressure; Contrast Media; Dogs; Humans; Hyperte | 1963 |
[PATHOGENIC AND PATHOPHYSIOLOGIC STUDY OF ASCITES IN CIRRHOTIC PATIENTS, AND ESPECIALLY IN NORTH AFRICAN SPLENOMEGALIC CIRRHOSES].
Topics: Africa; Africa, Northern; Ascites; Humans; Hypertension; Hypertension, Portal; Kidney Diseases; Live | 1963 |
IDENTIFICATION OF THE PRESSOR SUBSTANCE PRODUCED IN EXPERIMENTAL NEPHRITIS AND PREVENTION OF THE HYPERTENSION BY A SURGICAL PROCEDURE.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Edema; Hematuria; Hypertension; Liver Circul | 1963 |
EFFECTS OF ORAL DIURETICS ON RAISED ARTERIAL PRESSURE.
Topics: Arterial Pressure; Bendroflumethiazide; Benzothiadiazines; Blood; Blood Pressure Determination; Body | 1963 |
STUDY ON REGRESSION OF ATHEROSCLEROSIS IN RABBITS.
Topics: Animals; Arteriosclerosis; Atherosclerosis; Blood Chemical Analysis; Body Weight; Cholesterol; Dieta | 1963 |
[MALIGNANT ARTERIAL HYPERTENSION SYNDROME AND PYELONEPHRITIS].
Topics: Anti-Bacterial Agents; Antihypertensive Agents; Blood Chemical Analysis; Humans; Hypertension; Hyper | 1963 |
CLINICAL TRIAL OF A NEW ORAL DIURETIC, M & B 8430.
Topics: Blood Chemical Analysis; Blood Pressure; Blood Pressure Determination; Chlorides; Diuretics; Hyperte | 1964 |
[INVESTIGATIONS ON THE EXCHANGE OF FREE AMINO ACIDS AND UREA BETWEEN BLOOD AND CENTRAL NERVOUS SYSTEM].
Topics: Amino Acids; Blood; Brain; Bronchial Neoplasms; Central Nervous System; Cerebrovascular Circulation; | 1964 |
[EVOLUTION OF CHRONIC NEPHROPATHS WITH SEVERE OR MALIGNANT HYPERTENSION UNDER TREATMENT WITH GUANETHIDINE SULPHATE].
Topics: Adolescent; Cerebral Hemorrhage; Guanethidine; Hypertension; Hypertension, Malignant; Hypertension, | 1963 |
KIDNEY FUNCTION AFTER RENAL REVASCULARIZATION FOR HYPERTENSION.
Topics: Child; Creatine; Creatinine; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Function Test | 1964 |
GOUT, HYPERURICAEMIA AND CARBOHYDRATE METABOLISM.
Topics: Carbohydrate Metabolism; Cholesterol; Glucose Tolerance Test; Gout; Humans; Hypertension; Hyperurice | 1964 |
CLINICAL TRIAL OF TRIAMTERENE IN HYPERTENSIVE PATIENTS.
Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure Determination; Diuretics; Gout; Hyperal | 1964 |
[HYPERTENSION FROM THE STANDPOINT OF HUMAN VITALITY (2)].
Topics: Coronary Disease; Geriatrics; Heart Diseases; Heart Valves; Hypertension; Kidney Diseases; Urea | 1964 |
CHANGES IN RENAL FUNCTION IN LATE PREGNANCY.
Topics: Creatine; Creatinine; Diuresis; Estriol; Female; Humans; Hypertension; Kidney Function Tests; Postur | 1964 |
CONJOINT CLINIC ON DRUGS AND DIABETES.
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose | 1964 |
RENAL HOMOTRANSPLANTATION IN MAN; REPORT OF SIX CONSECUTIVE CASES.
Topics: Adolescent; Anuria; Azathioprine; Blood Chemical Analysis; Dactinomycin; Drug Therapy; Hypertension; | 1964 |
ONE YEAR'S EXPERIENCE WITH AN INTERMITTENT DIALYSIS PROGRAM.
Topics: Blood Chemical Analysis; Blood Urea Nitrogen; Creatine; Creatinine; Dialysis; Diet; Diet Therapy; Ed | 1964 |
THE USE OF METHYLDOPA IN HYPERTENSION.
Topics: Aspartate Aminotransferases; Biomedical Research; Blood; Blood Urea Nitrogen; Chlorothiazide; Drug T | 1964 |
THE VALUE OF THE UREA WASHOUT TEST IN THE ASSESSMENT OF CURABLE RENOVASCULAR HYPERTENSION.
Topics: Blood Urea Nitrogen; Child; Diatrizoate; Geriatrics; Headache; Humans; Hypertension; Hypertension, R | 1964 |
THE UREA WASH-OUT TEST. DETECTION OF CURABLE RENOVASCULAR HYPERTENSION.
Topics: Angiography; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Minnesota; Renal | 1965 |
RETINOPATHIES OF CHRONIC RENAL DISEASE; REVERSALS AFTER RENAL TRANSPLANTATION.
Topics: Arteriosclerosis; Blood Pressure; Blood Urea Nitrogen; Child; Creatine; Creatinine; Glomerulonephrit | 1965 |
HEMODIALYSIS FOR CHRONIC RENAL FAILURE. II. BIOCHEMICAL AND CLINICAL ASPECTS.
Topics: Anemia; Biochemical Phenomena; Biochemistry; Blood; Blood Pressure; Blood Urea Nitrogen; Calcium; Ch | 1965 |
REMEDIABLE HYPERTENSION DUE TO UNILATERAL RENAL DISEASE: CORRELATION OF SPLIT RENAL-FUNCTION TESTS AND PRESSOR ASSAYS OF RENAL VENOUS BLOOD IN HYPERTENSIVE PATIENTS.
Topics: Blood Pressure Determination; Diagnosis; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; | 1965 |
PRELIMINARY STUDIES ON THE ACTION OF QUINETHAZONE IN NORMAL SUBJECTS AND IN HYPERTENSIVE PATIENTS.
Topics: Blood; Chlorothiazide; Diuretics; Drug Therapy; Hypertension; Potassium; Quinazolines; Sodium; Sodiu | 1965 |
UMBILICAL CORD UREA IN TOXAEMIA OF PREGNANCY.
Topics: Birth Weight; Blood; Chemical Phenomena; Chemistry; Female; Humans; Hypertension; Pre-Eclampsia; Pre | 1965 |
INCREASED PULMONARY VASCULAR RESISTANCE IN THE DEPENDENT ZONE OF THE ISOLATED DOG LUNG CAUSED BY PERIVASCULAR EDEMA.
Topics: Chemotherapy, Cancer, Regional Perfusion; Dogs; Edema; Hypertension; Hypertension, Pulmonary; Lung; | 1965 |
The effect of urea upon the urinary excretion of electrolytes in patients with essential hypertension.
Topics: Electrolytes; Essential Hypertension; Humans; Hypertension; Urea; Water-Electrolyte Balance | 1962 |
[Clearance tests in diagnostic and prognostic examination of high blood pressure].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Prognosis; Urea | 1950 |
[Arterial hypertensive, blood urea and glycemia response to adrenal decapsulation and adrenalin injections].
Topics: Adrenalectomy; Arteries; Blood; Epinephrine; Humans; Hypertension; Urea | 1951 |
[Arterial hypertensive, blood urea and glycemia responses to decapsulation of the adrenal and injection of adrenalin].
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Arteries; Blood Glucose; Humans; Hypertension; Urea | 1951 |
Plasma and urinary vascular endothelial growth factor and diabetic nephropathy in Type 2 diabetes mellitus.
Topics: Albuminuria; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Fe | 2004 |
Why does the spontaneously hypertensive rat have an exaggerated preference for sweet and salty solutions? An hypothesis.
Topics: Animals; Drinking Behavior; Food Preferences; Glucose; Hypertension; Isotonic Solutions; Male; Osmot | 2004 |
Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose-fed rats.
Topics: Animals; Biological Transport; Blood Glucose; Blood Pressure; Calcium-Transporting ATPases; Creatine | 2004 |
[Inhibitors of arginase pathway in L-arginine metabolism as a new class of antihypertensive drugs: action of urea on oxidative and nonoxidative metabolism of L-arginine and vascular tone in chronic hypertension].
Topics: Animals; Antihypertensive Agents; Aorta; Arginase; Arginine; Disease Models, Animal; Enzyme Inhibito | 2004 |
Ionic and allied variations in normotensive and hypertensive diabetic patients.
Topics: Blood Glucose; Calcium; Case-Control Studies; Creatinine; Diabetes Complications; Electrolytes; Eryt | 2005 |
Sleep disorders in hemodialyzed patients--the role of comorbidities.
Topics: Age Factors; Aged; Antihypertensive Agents; Body Water; Body Weight; Comorbidity; Female; Humans; Hy | 2005 |
Immunosuppression based on mycophenolate mofetil in stable liver transplanted patients.
Topics: Aged; Calcineurin Inhibitors; Creatinine; Drug Therapy, Combination; Female; Graft Rejection; Humans | 2006 |
Clinical risk factors and the role of VDR gene polymorphisms in diabetic retinopathy in Polish type 2 diabetes patients.
Topics: Body Mass Index; Cholesterol; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Di | 2006 |
Evaluation of insulin resistance and sodium sensitivity in normotensive offspring of hypertensive individuals.
Topics: Adult; Blood Pressure; Child; Child of Impaired Parents; Cholesterol; Female; Genetic Predisposition | 2007 |
Prevalence of Balkan endemic nephropathy has not changed since 1971 in the Kolubara region in Serbia.
Topics: Adult; Aged; Aged, 80 and over; Alpha-Globulins; Balkan Nephropathy; Creatinine; Cross-Sectional Stu | 2007 |
Renal response to an acute protein challenge in pregnant women with borderline hypertension.
Topics: Adult; Analysis of Variance; Chlorides; Creatine; Female; Humans; Hypertension; Kidney; Osmolar Conc | 2007 |
Risk of live kidney donation--Indian perspective.
Topics: Adult; Age Factors; Albuminuria; Blood Pressure; Creatinine; Female; Follow-Up Studies; Glomerular F | 2007 |
Associations between sympathetic activity, plasma concentrations of renin, aldosterone, and parathyroid hormone, and the degree of intractability of blood pressure control in modialysis patients.
Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Epinephrine | 2007 |
Investigation of urea clearance in hypertensive disease.
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Urea | 1949 |
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Chromatography, Liquid; | 2008 |
Effects of long-term losartan and L-arginine treatment on haemodynamics, glomerular filtration, and SOD activity in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Abdominal; Arginin | 2008 |
Treatment with the arginase inhibitor N(omega)-hydroxy-nor-L-arginine improves vascular function and lowers blood pressure in adult spontaneously hypertensive rat.
Topics: Animals; Aorta, Thoracic; Arginase; Arginine; Blood Glucose; Blood Pressure; Body Weight; Endotheliu | 2008 |
Low-dose landiolol for hypertension with tachycardia following neurosurgery.
Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Female; Humans; Hypertension; M | 2008 |
Severe hypertension in childhood.
Topics: Aortic Coarctation; Child, Preschool; Female; Glomerulonephritis; Humans; Hypertension; Infant; Infa | 1967 |
Simplified bilateral differential function studies in hypertensive patients utilizing radioactive clearance techniques.
Topics: Adult; Aged; Cobalt Isotopes; Diuresis; Diuretics; Female; Glomerular Filtration Rate; Humans; Hyper | 1967 |
Abnormal glucose-tolerance test in the Natal Indian and African hypertensive patient.
Topics: Adolescent; Adult; Black or African American; Black People; Coronary Disease; Diabetes Complications | 1967 |
Salivary electrolytes, urea nitrogen, uric acid and salt taste thresholds in hypertension.
Topics: Aldosterone; Chlorine; Citrates; Humans; Hypertension; Parotid Gland; Potassium; Saliva; Secretory R | 1967 |
Hematological effects of alpha-methyldopa.
Topics: Adult; Aged; Anemia, Hemolytic; Blood Group Antigens; Coombs Test; Erythrocyte Aging; Female; Hemogl | 1967 |
Guanethidine and hypertension after five years.
Topics: Albuminuria; Angina Pectoris; Blood Pressure; Cerebrovascular Disorders; Female; Follow-Up Studies; | 1967 |
[Studies of audiogenic hypertension. I. Preventive effect of ethylcrotonylurea, maprobamate and pentobarbital on experimental audiogenic hypertension in rats].
Topics: Animals; Hypertension; Meprobamate; Noise; Pentobarbital; Rats; Urea | 1967 |
Significance of haematuria in hypertensive patients.
Topics: Adult; Age Factors; Hematuria; HLA Antigens; Humans; Hypertension; Immunoglobulin A; Urea | 1980 |
The heterogeneity of essential hypertension. Relation between lithium efflux and sodium content of erythrocytes and a family history of hypertension.
Topics: Adult; Aged; Creatinine; Erythrocytes; Female; Humans; Hypertension; Lithium; Male; Middle Aged; Pot | 1982 |
Cardiovascular responses in spontaneously hypertensive rats with acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Electric Stimulation; Heart Rate; Hemodynamics; Hypert | 1984 |
Changes in renal function induced by endralazine, a new antihypertensive drug.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate | 1983 |
Pinacidil monotherapy for hypertension.
Topics: Adult; Antihypertensive Agents; Body Weight; Female; Guanidines; Humans; Hypertension; Male; Middle | 1984 |
[Continuous ambulatory peritoneal dialysis. An alternative to hemodialysis].
Topics: Adult; Aged; Anemia; Creatinine; Female; Humans; Hyperkalemia; Hypertension; Kidney Failure, Chronic | 1984 |
[Primary and secondary hypertension: value and limitations of a simple diagnostic work-up in the etiological definition of hypertensives in a general population].
Topics: Adult; Blood Glucose; Female; Humans; Hypertension; Male; Mass Screening; Middle Aged; Potassium; So | 1982 |
Spironolactone and amiloride in hypertensive patients with and without aldosterone excess.
Topics: Adult; Amiloride; Blood Pressure; Body Weight; Female; Humans; Hyperaldosteronism; Hypertension; Mal | 1980 |
Acceleration of hypotension and development of stroke in the spontaneously hypertensive rat by unilateral ureteral obstruction.
Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Hypertension; Kidney; Male; Nephrectomy; Protein | 1980 |
Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Surface Area; Body Weight; Hum | 1982 |
Dietary risk factors of stroke and hypertension in Japan -- Part 2: Validity of urinalysis for dietary salt and protein intakes under a field condition.
Topics: Adult; Cerebrovascular Disorders; Creatinine; Diet; Dietary Proteins; Female; Humans; Hypertension; | 1982 |
Dietary risk factors of stroke and hypertension in Japan -- Part 1: Methodological assessment of urinalysis for dietary salt and protein intakes.
Topics: Adult; Cerebrovascular Disorders; Creatinine; Diet; Dietary Proteins; Female; Humans; Hypertension; | 1982 |
Clinical features of hypertension in frequent and heavy alcohol drinkers.
Topics: Adult; Alanine Transaminase; Alcohol Drinking; Alcoholism; Aspartate Aminotransferases; Electrocardi | 1982 |
End-stage reflux nephropathy.
Topics: Adolescent; Adult; Child; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidn | 1981 |
Urea therapy for inappropriate antidiuretic hormone secretion from tuberculous meningitis.
Topics: Brain Edema; Diuresis; Humans; Hypertension; Hyponatremia; Inappropriate ADH Syndrome; Intracranial | 1980 |
Induction of pinocytosis in cerebral vessels by acute hypertension and by hyperosmolar solutions.
Topics: Acute Disease; Animals; Blood Vessels; Blood-Brain Barrier; Brain; Endothelium; Hypertension; Hypert | 1980 |
[Renal function and osmotic indicators of blood in various forms of arterial hypertension].
Topics: Adult; Blood Glucose; Female; Humans; Hypertension; Hypertension, Renal; Kidney; Male; Middle Aged; | 1980 |
Tienilic acid in the treatment of gout and hypertension.
Topics: Adult; Blood Chemical Analysis; Blood Pressure; Creatinine; Glycolates; Gout; Humans; Hypertension; | 1980 |
Successful pregnancy in severe chronic renal failure not requiring dialysis.
Topics: Adult; Creatinine; Female; Humans; Hypertension; Kidney Failure, Chronic; Pregnancy; Pregnancy Compl | 1980 |
Fish protein-rich diet attenuates hypertension induced by dietary NG-nitro-L-arginine in normotensive Wistar-Kyoto rats.
Topics: Animals; Arginine; Blood Pressure; Dietary Proteins; Fishes; Heart Rate; Hypertension; Male; Rats; R | 1994 |
Effects of captopril and hydralazine on progression of adriamycin nephropathy in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Captopril; Doxorubicin; Female; Glomerulonephritis; Hematocrit | 1994 |
The duration of hypertension in the puerperium of preeclamptic women: relationship with renal impairment and week of delivery.
Topics: Adult; Blood Pressure; Female; Gestational Age; Humans; Hypertension; Kidney Diseases; Parity; Postp | 1994 |
Vitamin E did not prevent platelet activation, but prevented increase of lipid peroxides and renal dysfunction in DOCA-salt hypertensive rats.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Heart; Hypertension; Kidney; Lipid Metabolism; Lipid | 1993 |
Pressor mechanisms in adriamycin-induced nephropathy with hypertension in rats.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Cholesterol; Creatinine; Doxorubicin; H | 1994 |
[Kidney function in pregnant women with arterial hypertension].
Topics: Adult; Blood Proteins; Case-Control Studies; Female; Humans; Hypertension; Kidney Function Tests; Pr | 1995 |
[The effect of hypertension severity in pregnant women and during birth on renal function].
Topics: Adult; Female; Humans; Hypertension; Kidney Function Tests; Parity; Pregnancy; Pregnancy Complicatio | 1995 |
Risk factors for ischaemic heart disease and stroke mortality in young and old hypertensive patients.
Topics: Adult; Age Distribution; Aged; Cerebrovascular Disorders; Cholesterol; Female; Humans; Hypertension; | 1995 |
Recombinant erythropoietin increases blood pressure in experimental hypertension and uraemia without change in vascular cytosolic calcium.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Creatinine; Cytosol; Erythr | 1996 |
Heart failure in Nigerian hypertensive patients: the role of renal dysfunction.
Topics: Analysis of Variance; Blood Pressure; Creatinine; Female; Heart Failure; Hemoglobins; Humans; Hypert | 1995 |
Urinary calcium excretion in treated and untreated essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Benzothiadiazines; Blood G | 1996 |
Hypertension from carotid occlusion decreases renal papillary plasma flow, hypotension from hemorrhage increases it, an autoregulatory paradox.
Topics: Animals; Blood Pressure; Carotid Stenosis; Hematocrit; Hemorrhage; Homeostasis; Hypertension; Hypote | 1996 |
Serum angiotensin-converting enzyme activity in patients with endemic nephropathy.
Topics: Adult; Arteries; Balkan Nephropathy; Blood Pressure; Creatinine; Female; Humans; Hypertension; Male; | 1996 |
Biochemical changes during moduretic treatment of hypertension in African patients.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Glucose; Blood Proteins; Calcium; Chlorides; | 1995 |
Death on dialysis and the time/flux trade-off.
Topics: Convection; Diffusion; Female; Hemofiltration; Humans; Hypertension; Kidney Failure, Chronic; Male; | 1997 |
[Monitoring kidney function in patients with essential hypertension treated with enalapril].
Topics: Acetylglucosaminidase; Adult; Aged; Antihypertensive Agents; Creatinine; Enalapril; Female; Humans; | 1997 |
Kidneys from normotensive donors lower blood pressure in young transplanted spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Creatinine; Hypertension; Kidney Transplantation; Male; Rats; Rats, Inbred | 1997 |
Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension.
Topics: Alanine; Animals; Arginine; Argininosuccinate Synthase; Blood Pressure; Body Weight; Citrulline; Dis | 1998 |
Daily versus standard hemodialysis: one year experience.
Topics: Adult; Aged; Anemia; Arteriovenous Shunt, Surgical; Blood Pressure; Energy Intake; Erythropoietin; F | 1998 |
Preventive effects of Shichimotsu-koka-to on renal lesions in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Creatinine; Drinking; Drugs, Chinese Herbal; Eating; Free Radical | 1998 |
Salt-induced hypertension in Dahl salt-resistant and salt-sensitive rats with NOS II inhibition.
Topics: Amidines; Animals; Benzylamines; Drug Resistance; Enzyme Inhibitors; Female; Hypertension; Male; Mic | 1999 |
Taurine attenuates hypertension and improves insulin sensitivity in the fructose-fed rat, an animal model of insulin resistance.
Topics: Animals; Blood Glucose; Blood Pressure; Creatinine; Disease Models, Animal; Fructose; Glucose Tolera | 1999 |
Effects of SA7060, a novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, on deoxycorticosterone acetate-salt-induced hypertension in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Cardiomegaly; | 2000 |
[Disorders of endothelium-dependent vascular reactions and of the arginase and NO-synthase pathways of L-arginine metabolism in arterial hypertension].
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginase; Arginine; Endothelium, Vascular; Hypertension; In | 2000 |
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Blood Pressure; Cytosol; Eicosanoids; Enzym | 2000 |
Effects of acute and chronic hypertension on the labyrinthine barriers in rat.
Topics: Acute Disease; Animals; Chronic Disease; Cochlea; Ear, Inner; Endolymph; Hypertension; Male; Mannito | 2001 |
Genetic variation in the human urea transporter-2 is associated with variation in blood pressure.
Topics: Blood Pressure; Carrier Proteins; China; DNA; DNA Primers; Exons; Female; Genetic Variation; Humans; | 2001 |
[Inhibitors of arginase in the L-arginine metabolic pathway as a new class of antihypertensive drugs: effect of carbamide on lipid oxidative metabolism and on vessel tonus during arterial hypertension].
Topics: Animals; Antihypertensive Agents; Aorta; Arginase; Arginine; Blood Pressure; Endothelium, Vascular; | 2001 |
Relation of urinary urea to blood pressure: interaction with urinary sodium.
Topics: Adult; Aged; Blood Pressure; Dietary Proteins; Female; Humans; Hypertension; Kidney; Male; Middle Ag | 2002 |
Fetal uninephrectomy leads to postnatal hypertension and compromised renal function.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Female; Fetus; Glomerular Filtration Rate | 2002 |
Nephrotic syndrome in indian children.
Topics: Adolescent; Age Factors; Amyloidosis; Child; Child, Preschool; Edema; Female; Glomerulonephritis; He | 1975 |
Hypertensive crisis, erythrocytosis, and uraemia due to renal-artery stenosis of kidney transplants.
Topics: Adult; Angiography; Blood Pressure; Creatinine; Diagnostic Techniques, Surgical; Hemoglobins; Humans | 1975 |
Total body and serum potassium during prolonged thiazide therapy for essential hypertension.
Topics: Bendroflumethiazide; Bicarbonates; Blood Pressure; Blood Pressure Determination; Humans; Hypertensio | 1975 |
Deterioration of glucose tolerance in hypertensive patients on prolonged diuretic treatment.
Topics: Administration, Oral; Adult; Aged; Benzothiadiazines; Blood Glucose; Blood Pressure; Body Weight; Di | 1976 |
Evidence of cadmium toxicity in a population living in a zinc-mining area. Pilot survey of Shipham residents.
Topics: Acetylglucosaminidase; Adult; Aged; beta 2-Microglobulin; Blood Pressure; Cadmium; Cadmium Poisoning | 1979 |
Risk factors for death in treated hypertensive patients. Report from the D.H.S.S. Hypertension Care Computing Project.
Topics: Age Factors; Aged; Blood Pressure; England; Female; Follow-Up Studies; Humans; Hypertension; Kidney; | 1979 |
Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure.
Topics: Bethanidine; Cardiomegaly; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guanidines; Heart Ra | 1975 |
Results of adrenal surgery in patients with hypertension, aldosterone excess, and low plasma renin concentration.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Angiotensin II; Blood Pres | 1975 |
Dissociation between renin and arterial pressure responses to beta-adrenergic blockade in human essential hypertension.
Topics: Adrenergic beta-Antagonists; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Diuretics; Drug Ad | 1975 |
Kallikrein-kinin system in one- and two-kidney Goldblatt hypertensive rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kallikreins; Kidney; Kininogens; Male | 1979 |
[The early diagnosis of nephrologic and urologic diseases during pregnancy from an obstetrical point of view].
Topics: Abortion, Induced; Creatinine; Female; Humans; Hypertension; Kidney Diseases; Patient Care Team; Pla | 1979 |
[Dangers of a wrong diet in patients with renal insufficiency in the predialytic state or during chronic hemodialysis].
Topics: Amino Acids; Anemia; Dietary Proteins; Edema; Electrolysis; Energy Metabolism; Humans; Hyperkalemia; | 1977 |
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult | 1978 |
Plasma renin activity in psychosocial hypertension of CBA mice.
Topics: Animals; Blood Pressure; Body Weight; Hematocrit; Hypertension; Male; Mice; Mice, Inbred CBA; Psycho | 1978 |
The effect of chronic uremia on fatty acid metabolism in the heart.
Topics: Animals; Blood Pressure; Body Weight; Carnitine; Chronic Disease; Creatinine; Fatty Acids; Hematocri | 1978 |
Synthesis and evaluation of 3-substituted 1-[4-(2-indol-3-ylethyl)piperazinyl]ureas as potential antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Hypertension; Piperazines; Rats; Structure-Activity Relationship; | 1978 |
Chronic hemofiltration. A critical evaluation of a new method for the treatment of blood.
Topics: Adult; Aged; Creatinine; Evaluation Studies as Topic; Filtration; Hematocrit; Humans; Hypertension; | 1978 |
Relationship of prostaglandins and sodium in renal papilla in Kyoto hypertensive rats and during high sodium diets.
Topics: Age Factors; Animals; Diet; Hypertension; Indomethacin; Kidney Medulla; Meclofenamic Acid; Prostagla | 1978 |
Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension.
Topics: Angiotensin II; Animals; Antibodies; Arginine Vasopressin; Blood Pressure; Body Weight; Desoxycortic | 1977 |
Skin changes after transplantation.
Topics: Filtration; Humans; Hypertension; Insulin; Kidney Failure, Chronic; Lipids; Urea | 1977 |
A prospective study of patients with radiological pyelonephritis, papillary necrosis and obstructive atrophy.
Topics: Adolescent; Adult; Age Factors; Bacteriuria; Creatinine; Female; Humans; Hypertension; Kidney Calcul | 1976 |
Abnormality in metabolism of 15N-labeled nitrate in toxemia.
Topics: Adult; Ammonia; Female; Humans; Hypertension; Nitrates; Nitrogen; Nitrogen Isotopes; Pre-Eclampsia; | 1976 |
Plasma urea in hypertensive patients.
Topics: Age Factors; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Sex Factors; Tim | 1976 |
Discriminant function analysis of factors related to myocardial infarction in male patients on antihypertensive therapy.
Topics: Age Factors; Blood Pressure; Body Weight; Cholesterol; Humans; Hypertension; Male; Middle Aged; Myoc | 1976 |
Routine intravenous urography in the investigation of hypertension.
Topics: Age Factors; Blood Pressure; Female; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Mal | 1976 |
[Effect of alphamethyldopa on kidney function and of plasma renin activity in arterial hypertensive syndromes].
Topics: Adult; Glomerular Filtration Rate; Humans; Hypertension; Metabolic Clearance Rate; Methyldopa; Middl | 1976 |
Raised intracranial pressure. Diagnosis and management.
Topics: Cerebrovascular Disorders; Dexamethasone; Glucose; Glycerol; Humans; Hypertension; Intracranial Pres | 1975 |
Successful pregnancy in patient on regular dialysis.
Topics: Adult; Creatinine; Female; Fetus; Growth; Hemoglobins; Humans; Hypertension; Infant; Infant, Newborn | 1975 |
Plasma renin levels in Zulu hypertensives.
Topics: Black or African American; Black People; Female; Humans; Hypertension; Hypertension, Malignant; Hype | 1975 |
High blood pressure. detection and treatment by general practitioners.
Topics: Attitude of Health Personnel; Blood Pressure; Blood Pressure Determination; Cholesterol; Electrocard | 1975 |
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H | 1975 |
An evaluation of human placental lactogen levels in hypertension of pregnancy.
Topics: Asphyxia Neonatorum; Birth Weight; Creatinine; Female; Fetal Blood; Fetal Diseases; Humans; Hyperten | 1975 |
Serum uric acid in hypertensive patients.
Topics: Adult; Age Factors; Aged; Benzothiadiazines; Blood Pressure; Diuretics; Female; Humans; Hypertension | 1975 |
Hemodialysis 1991.
Topics: Dietary Proteins; Humans; Hypertension; Kidney Failure, Chronic; Nutrition Disorders; Peritoneal Dia | 1992 |
Course of left ventricular hypertrophy and function in end-stage renal disease after renal transplantation.
Topics: Arteriovenous Shunt, Surgical; Body Surface Area; Body Weight; Cardiomegaly; Creatinine; Echocardiog | 1992 |
Survival as an index of adequacy of dialysis.
Topics: Adult; Arteriosclerosis; Blood Pressure; Female; France; Humans; Hypertension; Kidney Failure, Chron | 1992 |
Effects of cicletanine on vasoactive systems in conscious sinoaortic-denervated dogs.
Topics: Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; C | 1991 |
[Effect of hypotensive treatment on renal function in patients with pseudo-hypertension].
Topics: Aged; Creatinine; Female; Furosemide; Humans; Hypertension; Kidney; Male; Middle Aged; Urea | 1991 |
The haemodynamic effects of long term felodipine therapy in previously untreated essential hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiovascular System; Creatinine; Drug Administration Schedule; Felodi | 1990 |
Physiological and immunopathological consequences of active immunization of spontaneously hypertensive and normotensive rats against murine renin.
Topics: Aldosterone; Angiotensinogen; Animals; Homeostasis; Hypertension; Immunization; Kidney; Male; Mice; | 1990 |
Adverse effects of captopril in hospital outpatients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Captopril; Creatinine; Diuretics; Drug Therapy, Comb | 1990 |
Therapy of diseased stroke-prone spontaneously hypertensive rats with nimodipine.
Topics: Aging; Animals; Brain; Calcium; Cerebrovascular Disorders; Creatinine; Hypertension; Kidney; Male; M | 1990 |
Hypertension in rats induced by renal grafts from renovascular hypertensive donors.
Topics: Animals; Blood Pressure; Drinking; Glomerular Filtration Rate; Hybridization, Genetic; Hypertension; | 1990 |
Peritoneal functional parameters after five years on continuous ambulatory peritoneal dialysis (CAPD): the effect of late peritonitis.
Topics: Adrenergic beta-Antagonists; Bacterial Infections; Creatinine; Female; Humans; Hypertension; Kidney | 1989 |
[The role of homeostatic function of the kidneys in the development of hyperuricemia].
Topics: Adult; Aged; Blood Proteins; Coronary Disease; Creatinine; Homeostasis; Humans; Hypertension; Kidney | 1989 |
Low dose, twice daily captopril and frusemide: a safe, effective and flexible third line treatment regimen for hypertension.
Topics: Adult; Aged; Captopril; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up S | 1989 |
Mild hypertension in patients with suspected dilated cardiomyopathy: cause or consequence?
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiomyopathy, Dilated; Electrolytes; Female; Heart Rate; | 1988 |
[Canrenone: an effective antihypertensive in an experimental model of hypertension in which the active transport of sodium is diminished].
Topics: Animals; Antihypertensive Agents; Canrenone; Cell Membrane Permeability; Creatinine; Diuresis; Hyper | 1986 |
Hypertension and nephrotoxic lesions in rats 1 year after prenatal exposure to gentamicin.
Topics: Animals; Female; Gentamicins; Hypertension; Kidney; Kidney Diseases; Male; Microscopy, Electron; Pre | 1988 |
Nephrotoxicity of cyclosporine in spontaneously hypertensive rats: effects on blood pressure and vascular lesions.
Topics: Animals; Blood Pressure; Body Weight; Creatinine; Cyclosporins; Heart Rate; Hypertension; Kidney Dis | 1986 |
Development of hypertension and proteinuria with age in fawn-hooded rats.
Topics: Animals; Blood Pressure; Body Weight; Creatinine; Diuresis; Drinking; Eating; Hematuria; Hypertensio | 1986 |
Parenteral chlorpromazine and frusemide: safe and effective treatment for hypertensive emergencies.
Topics: Adult; Aged; Chlorpromazine; Creatinine; Drug Therapy, Combination; Emergencies; Female; Furosemide; | 1986 |
High potassium diets markedly protect against stroke deaths and kidney disease in hypertensive rats, a possible legacy from prehistoric times.
Topics: Animals; Brain; Cerebrovascular Disorders; Diet; Hypertension; Kidney Diseases; Kidney Tubules; Musc | 1986 |
[Diagnosis of diabetic nephropathy].
Topics: Albuminuria; Basement Membrane; beta 2-Microglobulin; Creatinine; Diabetic Nephropathies; Diabetic R | 1985 |
Adrenergic-induced enhancement of brain barrier system permeability to small nonelectrolytes: choroid plexus versus cerebral capillaries.
Topics: Acetazolamide; Animals; Blood; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; C | 1985 |
Age-dependent blood pressure response to increased salt intake in rats influenced by a transient renal ischaemia.
Topics: Age Factors; Animals; Blood Pressure; Body Fluids; Hypertension; Ischemia; Kidney; Male; Rats; Rats, | 1986 |
The survival of treated hypertensive patients and their causes of death: a report from the DHSS hypertensive care computing project (DHCCP).
Topics: Adolescent; Adult; Aged; Blood Glucose; Cerebrovascular Disorders; Coronary Disease; England; Female | 1986 |
The effects of piretanide capsules on blood pressure during ergometric and isometric work loads in patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Capsules; Cholesterol; Creatinine; Diuretics; Female; Hu | 1985 |
Use of frusemide in severe toxaemia of pregnancy.
Topics: Adult; Antihypertensive Agents; Female; Furosemide; Humans; Hypertension; Methyldopa; Pre-Eclampsia; | 1972 |
Diagnosis, characterization and management of post-obstructive diuresis.
Topics: Aged; Creatinine; Desoxycorticosterone; Diuresis; Edema; Heart Failure; Humans; Hypertension; Infusi | 1973 |
[Relation between arterial pressure and various biological factors in serum].
Topics: Arteries; Beta-Globulins; Blood Chemical Analysis; Blood Glucose; Blood Pressure; Blood Proteins; Ch | 1972 |
Antihypertensive treatment and the course of established cerebral vascular disease.
Topics: Angina Pectoris; Antihypertensive Agents; Cardiomegaly; Cerebrovascular Disorders; Diuretics; Female | 1973 |
Tolerance and side effects during long term treatment of hypertension with debrisoquine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Cardiomegaly; Debrisoquin; Drug T | 1972 |
[Hypertension. Diagnosis and therapy in practice].
Topics: Adrenergic beta-Antagonists; Creatinine; Diuretics; Drug Combinations; Humans; Hypertension; Lipid M | 1974 |
Clinical investigation of the effects of adrenal corticosteroid excess on the colon.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Aldosterone; Colon; C | 1969 |
A study of the cytoplasmic granules in renal papillary interstitial cells in relation to hypertension.
Topics: Animals; Cytoplasmic Granules; Diet; Female; Histocytochemistry; Hypertension; Kidney; Male; Microsc | 1968 |
Predicting death from renal failure in primary hypertension.
Topics: Acute Kidney Injury; Age Factors; Blood Pressure; Cardiomegaly; Creatinine; Female; Humans; Hyperten | 1969 |
Investigation of albumin metabolism in man.
Topics: Amino Acids; Carbon Isotopes; Carcinoma, Hepatocellular; Celiac Disease; Humans; Hypertension; Liver | 1967 |
Prolonged peritoneal dialysis in patients awaiting renal transplantation.
Topics: Adolescent; Adult; Anemia; Anti-Bacterial Agents; Blood Proteins; Blood Transfusion; Child; Diet; Fe | 1968 |
[Correlations between plasma renin activity and blood pressure, erythrocyte count, hemoglobin, hematocrit as well as sodium, potassium, urea and creatinine in serum of hypertensive patients].
Topics: Adolescent; Adult; Aged; Angiotensin II; Aortic Coarctation; Blood Pressure; Creatinine; Erythrocyte | 1971 |
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pr | 1972 |
Renin in hypertension: how important as a risk factor?
Topics: Adult; Angiotensin II; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Cerebrovascular Disorders; C | 1973 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extr | 1973 |
[Electrolyte balance, plasma renin concentration and reaction of blood pressure in patients with essential hypertension and control subjects during therapy with metolazone, a new diuretic].
Topics: Blood Pressure; Calcium; Chlorides; Creatinine; Diet, Sodium-Restricted; Diuretics; Hematocrit; Huma | 1974 |
Modern concepts in diuretic therapy.
Topics: Blood Volume; Creatinine; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hyperten | 1974 |
Proceedings: The relation of antihypertensive treatment to plasma lipids and other vascular risk factors in hypertensives.
Topics: Adult; Benzothiadiazines; Coronary Disease; Diuretics; Female; Humans; Hypertension; Lipids; Male; M | 1974 |
Tuberculosis as a continuing cause of renal amyloidosis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Autopsy; Biopsy; C | 1974 |
Blood pressure in a Scottish town.
Topics: Blood Glucose; Blood Pressure; Body Height; Body Weight; Cholesterol; Electrocardiography; Female; H | 1974 |
Do medical conditions have an influence on central retinal vein occlusions?
Topics: Age Factors; Arterial Occlusive Diseases; Blood Viscosity; Diabetic Angiopathies; Hemoglobins; Human | 1974 |
[Hypertension with low level of plasma renin. An epidemiologic study].
Topics: Adult; Age Factors; Aged; Blood Pressure; Cholesterol; Creatinine; Female; Humans; Hypertension; Mal | 1974 |
[Dietary aspects in the treatment of obesity (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Exercise Therapy; Female; Humans; Hypertension; Lipids; Male; Obes | 1974 |
A study of the long-term effects of pre-eclampsia on blood pressue and renal function.
Topics: Adult; Bacteriuria; Blood Pressure; Female; Follow-Up Studies; Humans; Hypertension; Iodine Radioiso | 1974 |
Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension.
Topics: Adult; Aged; Amiloride; Calcium; Creatinine; Drug Combinations; Drug Tolerance; Humans; Hydrochlorot | 1974 |
Hypertension with renal impairment: influence of intensive therapy.
Topics: Adolescent; Adult; Chronic Disease; Creatinine; Diazoxide; Female; Glomerulonephritis; Humans; Hyper | 1974 |
Value of routine intravenous pyelography in the investigation of hypertension.
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Pyelonephritis; Urea; Urography | 1974 |
Serial estimation of urinary fibrin fibrinogen degradation products in kidney transplantation.
Topics: Anuria; Cadaver; Creatinine; Fibrin; Fibrinogen; Graft Rejection; Hemagglutination Inhibition Tests; | 1973 |
The treatment of chronic renal failure in children by regular dialysis and by transplantation.
Topics: Adolescent; Age Factors; Arteriovenous Shunt, Surgical; Bone Development; Child; Child, Preschool; C | 1973 |
Recurrent haematuria and mesangial IgA deposition.
Topics: Adolescent; Adult; Basement Membrane; Complement System Proteins; Creatinine; Female; Fluorescent An | 1973 |
The role of arterial pressure dynamics in the diagnosis of renal graft rejection crisis.
Topics: Adult; Arteries; Blood Pressure; Body Temperature; Cadaver; Creatinine; Diuresis; Glomerulonephritis | 1972 |
Anaesthesia and renal transplantation: an analysis of fifty-six cases.
Topics: Adolescent; Adult; Anesthesia, General; Atropine; Bicarbonates; Chlorides; Female; Hematocrit; Hemog | 1974 |
[Coronary arterio-venous difference in the concentration of various products of nitrogen metabolism in man].
Topics: Adult; Alanine; Ammonia; Aorta; Arteriosclerosis; Coronary Disease; Coronary Vessels; Glutamates; Gl | 1972 |
[Treatment of arterial hypertension with new drugs. 1. Severe arterial hypertension].
Topics: Antihypertensive Agents; Body Weight; Clonidine; Diuresis; Furosemide; Hemodynamics; Humans; Hyperte | 1972 |
The diagnostic and therapeutic value of spironolactone in patients with systemic hypertension.
Topics: Acid-Base Equilibrium; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Press | 1973 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Fe | 1973 |
Variations in size of the normal kidney following intravenous administration of water-soluble contrast medium and urea.
Topics: Adolescent; Adult; Aged; Anthropometry; Blood Pressure; Diatrizoate; Female; Humans; Hypertension; K | 1973 |
Hypertrichosis lanuginosa and a lichenoid eruption due to diazoxide therapy.
Topics: Adult; Biopsy; Creatinine; Diazoxide; Female; Humans; Hypertension; Hypertrichosis; Lichen Planus; P | 1973 |
Measurement of blood urea to assess the prognosis of hypertensive pregnancies.
Topics: Birth Weight; Female; Fetal Death; Humans; Hypertension; Infant Mortality; Pregnancy; Pregnancy Comp | 1973 |
A comparison of moduretic and hydrochlorothiazide in the treatment of hypertension in African patients.
Topics: Adult; Aged; Amiloride; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide | 1973 |
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Human | 1973 |
The mechanisms of fast renal compensation.
Topics: Animals; Dogs; Glomerular Filtration Rate; Hypertension; In Vitro Techniques; Kidney; Nephrectomy; P | 1973 |
The outcome of treatment and changes in presentation of primary hyperparathyroidism.
Topics: Adolescent; Adult; Aged; Blood Pressure; Bone Diseases; Cortisone; Creatinine; Female; Humans; Hyper | 1973 |
Clinicopathologic correlations in 100 children with the nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Female; Hematuria; Humans; Hypertension; Infant; Kidney; Male; | 1973 |
Familial hyperuricaemia and hypertriglyceridaemia.
Topics: Adolescent; Adult; Alcohol Drinking; Blood Pressure; Cholesterol; Female; Gout; Humans; Hyperlipidem | 1973 |
Surgical procedures on patients in end-stage renal failure.
Topics: Adolescent; Adult; Arteriovenous Shunt, Surgical; Child; Duodenal Ulcer; Female; Humans; Hypertensio | 1973 |
[Search for stenosis of the renal artery in arterial hypertension. Furosemide "wash-out" method].
Topics: Angiography; Diuresis; Female; Furosemide; Humans; Hypertension; Injections, Intravenous; Male; Midd | 1974 |
A critical evaluation of renal protein selectivity in pregnancy.
Topics: Creatinine; Female; Fetal Death; Humans; Hypertension; Immunoglobulin G; Kidney; Molecular Weight; P | 1974 |
[Arterial hypertension. Diagnosis and therapy in practice].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Creatinine; Electrocardiography; Exercise Ther | 1974 |
Blood urea changes in hypertensive patients according to therapy given, blood pressure control, and serum potassium levels.
Topics: Benzyl Compounds; Diuretics; Female; Glomerular Filtration Rate; Guanethidine; Guanidines; Humans; H | 1974 |
Salt taste in patients with essential hypertension and with hypertension due to primary hyperaldosteronism.
Topics: Adolescent; Adult; Blood Pressure Determination; Female; Hospitalization; Humans; Hydrochloric Acid; | 1974 |
Improvement in renal function following control of hypertension in azotaemics.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Creatinine; Female; Humans; Hypertension; Kidney F | 1974 |
Screening for urinary tract infection.
Topics: Adult; Age Factors; Bacteriuria; Blood Sedimentation; Child; Child, Preschool; England; Female; Heal | 1970 |
Surgical procedures in the elderly.
Topics: Aged; Anemia; Blood Volume; Female; Geriatrics; Heart Diseases; Humans; Hypertension; Lung Diseases; | 1972 |
Do urinary tract infections really matter in children?
Topics: Age Factors; Child; Child, Preschool; Chronic Disease; Humans; Hypertension; Infant; Infant, Newborn | 1972 |
Prospective study of electrocardiographic changes associated with subarachnoid haemorrhage.
Topics: Blood; Blood Glucose; Bradycardia; Consciousness; Electrocardiography; Fever; Humans; Hydrogen-Ion C | 1972 |
[Effects of a long-term administration on an antiserotonin agent, Lysenyl, in headaches of different origins].
Topics: Adult; Aged; Cerebrovascular Disorders; Ergolines; Erythrocytes; Female; Giant Cell Arteritis; Heada | 1972 |
Heart stroke associated with left hemiplegia, acute tubular necrosis, hypertension and myocardial damage.
Topics: Acute Kidney Injury; Adult; Biopsy; Body Temperature; Cardiomyopathies; Heat Exhaustion; Hemiplegia; | 1972 |
[Electrolyte changes following a long-term parenteral administration of NaCl to rabbits. Pathogenesis of salt hypertension].
Topics: Animals; Blood Pressure; Chlorides; Hypertension; Injections, Intravenous; Potassium; Rabbits; Sodiu | 1971 |
Idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia. A new syndrome.
Topics: Administration, Oral; Adult; Aged; Female; Hearing Disorders; Humans; Hydrochloric Acid; Hypertensio | 1971 |
Renal response to salt load in normotensive and hypertensive Nigerian males.
Topics: Black People; Blood Pressure Determination; Creatinine; Electrolytes; Environment; Glucose; Humans; | 1971 |
Use of diazoxide in hypertension with renal failure.
Topics: Adolescent; Adult; Blood Glucose; Creatine; Diazoxide; Dietary Proteins; Female; Humans; Hyperglycem | 1971 |
[Value of the electroencephalogram in chronic renal insufficiency].
Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Electrodiagnosis; Electroencephalography; Humans; Hy | 1970 |
[Diagnosis of arterial hypertension].
Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiography; Aortic Valve Stenosis; Arteries; Catecholamines | 1970 |
[On the nephrotoxic action of repeated injections of contrast medium during selective renal arteriography].
Topics: Albuminuria; Angiography; Contrast Media; Diagnosis, Differential; Humans; Hypertension; Hypertensio | 1967 |
Kidney disease and pregnancy.
Topics: Abortion, Therapeutic; Female; Glomerulonephritis; Humans; Hypertension; Kidney Diseases; Nephritis; | 1968 |
Nephropathy in chronic lead poisoning.
Topics: Adult; Chronic Disease; Colic; Creatinine; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Ki | 1968 |
Relationship of cytoplasmic granules in renal papillary interstitial cells to "postsalt" hypertension.
Topics: Animals; Cytoplasmic Granules; Histocytochemistry; Hypertension; Kidney; Male; Nephrectomy; Rats; Re | 1969 |
[Indices of the clearance of endogenous creatinine, urea and uric acid in patients with arterial hypertension].
Topics: Adult; Aged; Creatinine; Female; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Ure | 1969 |
Nephropathy in marathon runners.
Topics: Acute Kidney Injury; Adult; Alanine Transaminase; Anuria; Aspartate Aminotransferases; Diarrhea; Hem | 1969 |
[Physiological properties of tetracyclic systems present in the formula of steroids with two atoms of nitrogen in position 15 and 16].
Topics: Acidosis; Animals; Cardiovascular System; Cats; Chemical Phenomena; Chemistry; Dogs; Gonanes; Hypert | 1969 |
Normal or elevated haemoglobin values in chronic renal failure.
Topics: Adult; Blood Pressure; Creatinine; Erythrocyte Count; Erythropoiesis; Erythropoietin; Female; Glomer | 1969 |
The changing outlook for the patient with hypertension.
Topics: Antihypertensive Agents; Blood Urea Nitrogen; Humans; Hypertension; Hypertension, Malignant; Hyperte | 1966 |