Page last updated: 2024-10-21

urea and Auricular Fibrillation

urea has been researched along with Auricular Fibrillation in 91 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
"In GALACTIC-HF, the cardiac myosin activator omecamtiv mecarbil compared with placebo reduced the risk of heart failure events or cardiovascular death in patients with heart failure with reduced ejection fraction."9.51Influence of atrial fibrillation on efficacy and safety of omecamtiv mecarbil in heart failure: the GALACTIC-HF trial. ( Claggett, BL; Corbalan, R; Diaz, R; Felker, GM; Filippatos, G; Goudev, AR; Heitner, SB; Kupfer, S; Malik, FI; Mareev, V; McMurray, JJV; Metra, M; Miao, ZM; Serpytis, P; Solomon, SD; Suter, T; Teerlink, JR; Yilmaz, MB; Zannad, F, 2022)
"To investigate the efficacy of prophylactic administration of low-dose landiolol on postoperative atrial fibrillation (POAF) in patients after cardiovascular surgery."9.34Preventive effect of low-dose landiolol on postoperative atrial fibrillation study (PELTA study). ( Akiyama, M; Ito, K; Kaiho, Y; Katahira, S; Kumagai, K; Maeda, K; Matsuo, S; Saiki, Y; Sasaki, K; Sugawara, Y; Suzuki, T; Suzuki, Y; Tsuji, I, 2020)
"We investigated for the first time the suitability of landiolol, an ultra-short-acting β1-specific β-blocker, for the treatment of atrial fibrillation/atrial flutter (AF/AFL) in Caucasian patients."9.30Open-Label Two-Dose Pilot Study of Landiolol for the Treatment of Atrial Fibrillation/Atrial Flutter in Caucasian Patients. ( Domanovits, H; Hodisch, J; Husch, B; Kadlecová, P; Krumpl, G; Stix, G; Trebs, M; Unger, M; Wolzt, M, 2019)
"Perioperative landiolol administration suppressed the incidence of new-onset of AF as well as sinus tachycardia, and the plasma IL-6 elevation in patients undergoing esophageal cancer surgery."9.24The suppressive effects of landiolol administration on the occurrence of postoperative atrial fibrillation and tachycardia, and plasma IL-6 elevation in patients undergoing esophageal surgery: A randomized controlled clinical trial. ( Goyagi, T; Horiguchi, T; Horikoshi, Y; Kodama, S; Kudo, R; Nishikawa, T, 2017)
"The study was designed and designated the "HEARTFUL study" in the hope of establishing a basis for control of HEART rate in inFant and child tachyarrhythmia Using Landiolol in children with heart failure."9.24Study design for control of HEART rate in inFant and child tachyarrhythmia with heart failure Using Landiolol (HEARTFUL): A prospective, multicenter, uncontrolled clinical trial. ( Horigome, H; Iwamoto, M; Miura, M; Miyazaki, A; Nagano, T; Ohashi, N; Ono, H; Sagawa, K; Sakaguchi, H; Sumitomo, N; Suzuki, T; Takahashi, K; Takamuro, M; Takigiku, K; Tokunaga, C; Ueda, H; Ushinohama, H; Yoshimoto, J, 2017)
" Postoperative atrial fibrillation occurred in 15 patients (30 per cent) receiving placebo versus five (10 per cent) receiving landiolol (P = 0·012)."9.24Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer. ( Hayata, K; Kato, T; Katsuda, M; Kitadani, J; Nakamori, M; Nakamura, M; Ojima, T; Tabata, H; Takeuchi, A; Yamaue, H, 2017)
"We aimed to determine whether intraoperative low-dose infusion of landiolol, an ultra-short-acting beta blocker, can prevent postoperative atrial fibrillation (POAF) after lung resection."9.22Landiolol infusion during general anesthesia does not prevent postoperative atrial fibrillation in patients undergoing lung resection. ( Aoyama, H; Aoyama, Y; Otsuka, Y, 2016)
"Considering this analysis, landiolol was effective in the prevention of AF after cardiothoracic surgery and did not increase the risk of major postoperative complications."9.22Beta-Blocker Landiolol Hydrochloride in Preventing Atrial Fibrillation Following Cardiothoracic Surgery: A Systematic Review and Meta-Analysis. ( Chen, C; Hao, J; Liu, L; Peng, H; Xu, W; Zhang, J; Zhou, J, 2022)
"Low-dose infusion of landiolol hydrochloride prevented atrial fibrillation after cardiac surgery in patients with cardiac dysfunction and was safe, with no effect on blood pressure."9.20Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction: Prevention of Atrial Fibrillation After Cardiac Surgery With Landiolol Hydrochloride for Left Ventric ( Arimoto, M; Hata, H; Ishii, Y; Osaka, S; Sezai, A; Shiono, M; Yaoita, H, 2015)
"The goal of this prospective study was to examine the effects of landiolol hydrochloride on prevention of atrial fibrillation and on hemodynamics in the acute postoperative phase after heart valve surgery."9.16Efficacy of landiolol hydrochloride for prevention of atrial fibrillation after heart valve surgery. ( Hirai, H; Hosono, M; Nakahira, A; Sakaguchi, M; Sasaki, Y; Seo, H; Suehiro, S, 2012)
"We previously performed a trial of intravenous landiolol hydrochloride during and after cardiac surgery (the PASCAL trial) and demonstrated a preventive effect on postoperative atrial fibrillation (AF)."9.16Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: a pilot study. ( Hata, M; Hirayama, A; Kunimoto, S; Nakai, T; Sezai, A; Shiono, M; Yoshitake, I, 2012)
"Postoperative intravenous landiolol therapy followed by oral carvedilol may be more effective than oral carvedilol alone for prevention of atrial fibrillation after off-pump CABG."9.16Effect of postoperative landiolol administration for atrial fibrillation after off pump coronary artery bypass surgery. ( Bessho, R; Fujii, M; Ochi, M; Shimizu, K; Takeda, S; Terajima, K, 2012)
"Postoperative atrial fibrillation was reduced by treatment with landiolol hydrochloride."9.15Landiolol hydrochloride for prevention of atrial fibrillation after coronary artery bypass grafting: new evidence from the PASCAL trial. ( Hata, M; Hirayama, A; Minami, K; Nakai, T; Sezai, A; Shiono, M; Wakui, S; Yoshitake, I, 2011)
"Landiolol versus SoC in prevention of atrial fibrillation immediately after cardiac surgery."9.05Cost-Effectiveness Analysis of Landiolol, an Ultrashort-Acting Beta-Blocker, for Prevention of Postoperative Atrial Fibrillation for the Germany Health Care System. ( Heringlake, M; Walter, E, 2020)
"Despite the increasing application of tolvaptan in cardiac surgery, there is no information on the use of tolvaptan in Stanford patients with type A aortic dissection."8.31Efficacy of tolvaptan in postoperative volume therapy for acute Stanford type A aortic dissection. ( Gao, F; Gao, Y; He, X; Liu, W; Shi, L; Wang, W; Zhuang, X, 2023)
"Landiolol enables us to treat the patients with rapid atrial fibrillation (AF) with acute decompensated heart failure (ADHF) efficiently."8.12Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment. ( Abe, T; Ebina, T; Hanajima, Y; Hibi, K; Horii, M; Iwahashi, N; Kimura, K; Kimura, Y; Kirigaya, J; Kosuge, M; Matsuzawa, Y; Minamimoto, Y; Okada, K; Takahashi, H; Tamura, K, 2022)
"The HEARTFUL study has demonstrated the efficacy of landiolol, by reducing heart rate or terminating tachycardia, in pediatric patients with supraventricular tachyarrhythmias."8.12Control of Heart Rate in Infant and Child Tachyarrhythmia With Reduced Cardiac Function Using Landiolol (HEARTFUL) - Results of a Prospective, Multicenter, Uncontrolled Clinical Study. ( Aoki, H; Fukunaga, H; Horigome, H; Miura, M; Miyazaki, A; Morishima, E; Ohashi, N; Oki, K; Ono, H; Sagawa, K; Sakaguchi, H; Sato, S; Sumitomo, N; Suzuki, T; Takei, K; Ueda, H, 2022)
" Approximately 6 days after starting intravenous administration of amiodarone (600 mg/day) for maintaining sinus rhythm after cardioversion of AF, electrocardiograms revealed a prolonged QT interval associated with torsade de pointes (TdP)."8.02Suppression of amiodarone-induced torsade de pointes by landiolol in a patient with atrial fibrillation-mediated cardiomyopathy. ( Enomoto, D; Hyodo, T; Ikeda, S; Okura, T; Sakaue, T; Takahashi, K; Takemoto, M; Uemura, S; Utsunomiya, Y; Yamashita, M, 2021)
"Clinical experience with landiolol use in patients with atrial fibrillation (AF) and a severely depressed left ventricular (LV) function is limited."7.96Comparison of Landiolol and Digoxin as an Intravenous Drug for Controlling the Heart Rate in Patients with Atrial Fibrillation and Severely Depressed Left Ventricular Function. ( Akitsu, K; Fujino, T; Ikeda, T; Kinoshita, T; Koike, H; Shinohara, M; Suzuki, T; Wada, R; Yano, K, 2020)
"2%) received landiolol for atrial fibrillation."7.91A prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey. ( Mizutani, H; Nakasu, Y; Sumitani, K; Yamashita, T, 2019)
"The authors assessed the efficacy and safety of landiolol, an ultra-short-acting beta-blocker, with those of amiodarone in the restoration of sinus rhythm for postoperative atrial fibrillation (POAF) in intensive care unit (ICU) patients."7.83Efficacy and Safety of Landiolol Compared to Amiodarone for the Management of Postoperative Atrial Fibrillation in Intensive Care Patients. ( Fujino, Y; Ohta, N; Shibata, SC; Uchiyama, A, 2016)
"Landiolol hydrochloride can be effectively and safely used in patients who develop tachyarrhythmia after esophagectomy."7.80Effect of landiolol hydrochloride on tachyarrhythmia after esophagectomy. ( Fujii, T; Fujiwara, M; Iwata, N; Kobayashi, D; Kodera, Y; Koike, M; Nakayama, G; Niwa, Y; Sugimoto, H; Tanaka, C, 2014)
"The purpose of this study was to find a safe dosing regimen for landiolol, an ultra-short-acting β-adrenergic blocking agent, to rapidly control supraventricular tachyarrhythmias (SVTs) in patients with heart failure (HF)."7.80Novel use of the ultra-short-acting intravenous β1-selective blocker landiolol for supraventricular tachyarrhythmias in patients with congestive heart failure. ( Adachi, T; Aonuma, K; Baba, M; Hasegawa, T; Hiraya, D; Hoshi, T; Kuroki, K; Sato, A, 2014)
"The response to continuous intravenous infusion of landiolol was evaluated in 25 patients who developed post-operative atrial fibrillation or atrial flutter after major pulmonary resection."7.78Effect of landiolol hydrochloride, an ultra-short-acting beta 1-selective blocker, on supraventricular tachycardia, atrial fibrillation and flutter after pulmonary resection. ( Ibe, T; Kamiyoshihara, M; Kawashima, O; Nagashima, T; Nakano, T; Shimizu, K; Takeyoshi, I, 2012)
"Low-dose landiolol can be effective quickly and used safely in patients who develop atrial fibrillation after pulmonary resection for lung cancer."7.77Efficacy of low-dose landiolol, an ultrashort-acting β-blocker, on postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer. ( Funakoshi, Y; Maeda, H; Maekura, R; Nojiri, T; Okumura, M; Takeuchi, Y; Yamamoto, K, 2011)
"Intra-operative low-dose infusion of landiolol hydrochloride decreases the incidence of postoperative atrial fibrillation after OPCAB."7.76[Effect of intra-operative low-dose infusion of landiolol hydrochloride on post-operative atrial fibrillation after off-pump coronary artery bypass grafting]. ( Kurosawa, H; Sato, Y; Seto, Y; Takase, S; Wakamatsu, H; Yokoyama, H, 2010)
"Intraoperative and perioperative administration of low-dose landiolol has a preventive effect on the appearance of atrial fibrillation after CABG surgery."7.75Effect of low-dose landiolol, an ultrashort-acting beta-blocker, on postoperative atrial fibrillation after CABG surgery. ( Fujiwara, H; Kawamura, T; Namai, A; Sakurai, M, 2009)
"Postoperative treatment with carvedilol following landiolol has the effect of preventing tachycardia during AF after coronary artery bypass grafting."7.75Postoperative treatment of carvedilol following low dose landiolol has preventive effect for atrial fibrillation after coronary artery bypass grafting. ( Kawamura, T; Namai, A; Sakurai, M; Yoshioka, I, 2009)
"The purpose of this study was to investigate the efficacy of landiolol hydrochloride, a short-acting beta(1) blocker, by initiating its administration at a low dose (5 microg kg(-1) min(-1)) in patients with postoperative supraventricular arrhythmia."7.75Postoperative administration of landiolol hydrochloride for patients with supraventricular arrhythmia: the efficacy of sustained intravenous infusion at a low dose. ( Fukutomi, T; Nishimori, H; Radhakrishnan, G; Sasaguri, S; Wariishi, S; Yamamoto, M; Yamashita, K, 2009)
"We examined the effect of landiolol hydrochloride, a selective beta1-adrenoreceptor antagonist, on the incidence of atrial fibrillation(AF)."7.74[Use of landiolol hydrochloride for the prevention of atrial fibrillation after lung resection]. ( Ishimura, N; Kumano, H; Morioka, M; Nishiwada, M; Okita, T; Shinjo, T; Uji, M, 2008)
" During the intraoperative discrepancy between heart rate and pulse rate, continuous infusion of low dose landiolol was useful to control his heart rate of atrial fibrillation."7.73[Effect of landiolol on heart rate control of atrial fibrillation in a patient with sick sinus syndrome under ventricular pacing]. ( Kitoh, T; Kobayashi, K; Otagiri, T; Satoh, N, 2006)
"Landiolol is a recently innovated ultra-short-acting beta-blocker with 251-fold β1/β2 selectivity, which was originally indicated only to control peri-operative supra-ventricular tachyarrhythmia by 2013 in Japan."6.66Novel rate control strategy with landiolol in patients with cardiac dysfunction and atrial fibrillation. ( Imamura, T; Kinugawa, K, 2020)
"Landiolol is an ultra-short acting beta-blocker, and some randomized controlled trials of landiolol administration for the prevention of POAF have been conducted in Japan."6.50Perioperative landiolol administration reduces atrial fibrillation after cardiac surgery: A meta-analysis of randomized controlled trials. ( Hamasaki, T; Kitakaze, M; Sakamoto, A, 2014)
" No adverse effects were reported in any patient."5.62Safety and Efficacy of Landiolol Hydrochloride in Children with Tachyarrhythmia of Various Etiologies. ( Ashida, A; Kishi, K; Konishi, H; Nemoto, S; Odanaka, Y; Ozaki, N, 2021)
"In GALACTIC-HF, the cardiac myosin activator omecamtiv mecarbil compared with placebo reduced the risk of heart failure events or cardiovascular death in patients with heart failure with reduced ejection fraction."5.51Influence of atrial fibrillation on efficacy and safety of omecamtiv mecarbil in heart failure: the GALACTIC-HF trial. ( Claggett, BL; Corbalan, R; Diaz, R; Felker, GM; Filippatos, G; Goudev, AR; Heitner, SB; Kupfer, S; Malik, FI; Mareev, V; McMurray, JJV; Metra, M; Miao, ZM; Serpytis, P; Solomon, SD; Suter, T; Teerlink, JR; Yilmaz, MB; Zannad, F, 2022)
"Landiolol was ineffective in the majority of AFl/AT patients."5.51Differential Effectiveness of Landiolol Between Atrial Fibrillation and Atrial Flutter/Atrial Tachycardia Patients With Left Ventricular Dysfunction. ( Fujimoto, Y; Hayashi, H; Hayashi, M; Ito-Hagiwara, K; Iwasaki, YK; Maru, E; Oka, E; Shimizu, W; Yamamoto, T; Yodogawa, K, 2019)
"Thyroid storm is a life-threatening disorder that remains a therapeutic challenge."5.46Switching Therapy from Intravenous Landiolol to Transdermal Bisoprolol in a Patient with Thyroid Storm Complicated by Decompensated Heart Failure and Gastrointestinal Dysfunction. ( Fujita, M; Godo, S; Kawazoe, Y; Kudo, D; Kushimoto, S; Nomura, R; Ozaki, H; Shimokawa, H, 2017)
"The bisoprolol patch was introduced 88 h after the start of landiolol administration, when the rate was approximately 3 μg/kg/min."5.43Switching therapy from intravenous beta blocker to bisoprolol transdermal patch for atrial fibrillation tachycardia. ( Doi, K; Hiruma, T; Inokuchi, R; Nakajima, S; Nakamura, K; Tokunaga, K, 2016)
"The patient was a 20-year old male with dilated cardiomyopathy."5.42An Experience of Landiolol Use for an Advanced Heart Failure Patient With Severe Hypotension. ( Amiya, E; Endo, M; Hatano, M; Imamura, T; Inaba, T; Kinugawa, K; Komuro, I; Maki, H; Nitta, D, 2015)
"Landiolol hydrochloride was the first-line treatment in 46 patients and the only therapy in 26 patients."5.39Efficacy of landiolol hydrochloride for atrial fibrillation after open heart surgery. ( Fukushima, S; Kuratani, T; Miyagawa, S; Nishi, H; Saito, S; Sakaguchi, T; Sawa, Y; Ueno, T; Yoshikawa, Y, 2013)
"Landiolol hydrochloride is a new β-adrenergic blocker with a pharmacological profile that suggests it can be administered safely to patients who have sinus tachycardia or tachyarrhythmia and who require heart rate reduction."5.39Postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting or cardiac valve surgery: intraoperative use of landiolol. ( Kim, C; Kohda, S; Nakanishi, K; Sakamoto, A; Takeda, S, 2013)
"When landiolol was administered, enough attention should be paid to the patients whose left ventricular function was low."5.36[Clinical analysis of precaution against atrial fibrillation following cardiac surgery: landiolol or amiodarone?]. ( Abe, T; Fukuda, T; Haruna, T; Inoko, M; Ito, H; Miyamoto, S; Nakane, E; Nohara, R; Sasaki, K; Uehara, K; Ueyama, K, 2010)
"To investigate the efficacy of prophylactic administration of low-dose landiolol on postoperative atrial fibrillation (POAF) in patients after cardiovascular surgery."5.34Preventive effect of low-dose landiolol on postoperative atrial fibrillation study (PELTA study). ( Akiyama, M; Ito, K; Kaiho, Y; Katahira, S; Kumagai, K; Maeda, K; Matsuo, S; Saiki, Y; Sasaki, K; Sugawara, Y; Suzuki, T; Suzuki, Y; Tsuji, I, 2020)
"A 71-year-old woman with a history of persistent atrial fibrillation underwent clipping of a ruptured cerebral artery aneurysm."5.32Conversion of atrial fibrillation to sinus rhythm during landiolol infusion. ( Goto, M; Isomine, S; Kanazawa, T; Mayahara, T; Nakajima, H; Sakaida, K; Sato, M, 2004)
"We investigated for the first time the suitability of landiolol, an ultra-short-acting β1-specific β-blocker, for the treatment of atrial fibrillation/atrial flutter (AF/AFL) in Caucasian patients."5.30Open-Label Two-Dose Pilot Study of Landiolol for the Treatment of Atrial Fibrillation/Atrial Flutter in Caucasian Patients. ( Domanovits, H; Hodisch, J; Husch, B; Kadlecová, P; Krumpl, G; Stix, G; Trebs, M; Unger, M; Wolzt, M, 2019)
"The study was designed and designated the "HEARTFUL study" in the hope of establishing a basis for control of HEART rate in inFant and child tachyarrhythmia Using Landiolol in children with heart failure."5.24Study design for control of HEART rate in inFant and child tachyarrhythmia with heart failure Using Landiolol (HEARTFUL): A prospective, multicenter, uncontrolled clinical trial. ( Horigome, H; Iwamoto, M; Miura, M; Miyazaki, A; Nagano, T; Ohashi, N; Ono, H; Sagawa, K; Sakaguchi, H; Sumitomo, N; Suzuki, T; Takahashi, K; Takamuro, M; Takigiku, K; Tokunaga, C; Ueda, H; Ushinohama, H; Yoshimoto, J, 2017)
"Perioperative landiolol administration suppressed the incidence of new-onset of AF as well as sinus tachycardia, and the plasma IL-6 elevation in patients undergoing esophageal cancer surgery."5.24The suppressive effects of landiolol administration on the occurrence of postoperative atrial fibrillation and tachycardia, and plasma IL-6 elevation in patients undergoing esophageal surgery: A randomized controlled clinical trial. ( Goyagi, T; Horiguchi, T; Horikoshi, Y; Kodama, S; Kudo, R; Nishikawa, T, 2017)
" Postoperative atrial fibrillation occurred in 15 patients (30 per cent) receiving placebo versus five (10 per cent) receiving landiolol (P = 0·012)."5.24Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer. ( Hayata, K; Kato, T; Katsuda, M; Kitadani, J; Nakamori, M; Nakamura, M; Ojima, T; Tabata, H; Takeuchi, A; Yamaue, H, 2017)
"Considering this analysis, landiolol was effective in the prevention of AF after cardiothoracic surgery and did not increase the risk of major postoperative complications."5.22Beta-Blocker Landiolol Hydrochloride in Preventing Atrial Fibrillation Following Cardiothoracic Surgery: A Systematic Review and Meta-Analysis. ( Chen, C; Hao, J; Liu, L; Peng, H; Xu, W; Zhang, J; Zhou, J, 2022)
"We aimed to determine whether intraoperative low-dose infusion of landiolol, an ultra-short-acting beta blocker, can prevent postoperative atrial fibrillation (POAF) after lung resection."5.22Landiolol infusion during general anesthesia does not prevent postoperative atrial fibrillation in patients undergoing lung resection. ( Aoyama, H; Aoyama, Y; Otsuka, Y, 2016)
"Low-dose infusion of landiolol hydrochloride prevented atrial fibrillation after cardiac surgery in patients with cardiac dysfunction and was safe, with no effect on blood pressure."5.20Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction: Prevention of Atrial Fibrillation After Cardiac Surgery With Landiolol Hydrochloride for Left Ventric ( Arimoto, M; Hata, H; Ishii, Y; Osaka, S; Sezai, A; Shiono, M; Yaoita, H, 2015)
"Results from the multicenter trial (J-Land study) of landiolol versus digoxin in atrial fibrillation (AF) and atrial flutter (AFL) patients with left ventricular (LV) dysfunction revealed that landiolol was more effective for controlling rapid HR than digoxin."5.19Impacts of patient characteristics on the effectiveness of landiolol in AF/AFL patients complicated with LV dysfunction: Subgroup analysis of the J-Land study. ( Aiba, T; Atarashi, H; Daimon, T; Fujino, K; Hori, M; Ikeda, T; Imai, Y; Inoue, H; Kinugawa, K; Kitakaze, M; Nagai, R; Nagano, T; Okamura, T; Sakamoto, A; Seino, Y; Shimizu, W; Yamashita, T, 2014)
"The incidence of atrial fibrillation was significantly lower in the landiolol group compared to the control group (13/68, 19% vs."5.17Perioperative use of a beta blocker in coronary artery bypass grafting. ( Aoki, M; Baba, H; Goto, Y; Ogawa, S; Okawa, Y, 2013)
"We previously performed a trial of intravenous landiolol hydrochloride during and after cardiac surgery (the PASCAL trial) and demonstrated a preventive effect on postoperative atrial fibrillation (AF)."5.16Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: a pilot study. ( Hata, M; Hirayama, A; Kunimoto, S; Nakai, T; Sezai, A; Shiono, M; Yoshitake, I, 2012)
"The goal of this prospective study was to examine the effects of landiolol hydrochloride on prevention of atrial fibrillation and on hemodynamics in the acute postoperative phase after heart valve surgery."5.16Efficacy of landiolol hydrochloride for prevention of atrial fibrillation after heart valve surgery. ( Hirai, H; Hosono, M; Nakahira, A; Sakaguchi, M; Sasaki, Y; Seo, H; Suehiro, S, 2012)
"Postoperative intravenous landiolol therapy followed by oral carvedilol may be more effective than oral carvedilol alone for prevention of atrial fibrillation after off-pump CABG."5.16Effect of postoperative landiolol administration for atrial fibrillation after off pump coronary artery bypass surgery. ( Bessho, R; Fujii, M; Ochi, M; Shimizu, K; Takeda, S; Terajima, K, 2012)
"Postoperative atrial fibrillation was reduced by treatment with landiolol hydrochloride."5.15Landiolol hydrochloride for prevention of atrial fibrillation after coronary artery bypass grafting: new evidence from the PASCAL trial. ( Hata, M; Hirayama, A; Minami, K; Nakai, T; Sezai, A; Shiono, M; Wakui, S; Yoshitake, I, 2011)
" In paroxysmal atrial fibrillation, landiolol hydrochloride reduced the heart rate from 111 +/- 20 to 90 +/- 10/min."5.09Pharmacokinetics of landiolol hydrochloride, a new ultra-short-acting beta-blocker, in patients with cardiac arrhythmias. ( Atarashi, H; Endoh, Y; Hayakawa, H; Ino, T; Kuruma, A; Saitoh, H; Yashima, M, 2000)
"Landiolol versus SoC in prevention of atrial fibrillation immediately after cardiac surgery."5.05Cost-Effectiveness Analysis of Landiolol, an Ultrashort-Acting Beta-Blocker, for Prevention of Postoperative Atrial Fibrillation for the Germany Health Care System. ( Heringlake, M; Walter, E, 2020)
"Despite the increasing application of tolvaptan in cardiac surgery, there is no information on the use of tolvaptan in Stanford patients with type A aortic dissection."4.31Efficacy of tolvaptan in postoperative volume therapy for acute Stanford type A aortic dissection. ( Gao, F; Gao, Y; He, X; Liu, W; Shi, L; Wang, W; Zhuang, X, 2023)
"Landiolol enables us to treat the patients with rapid atrial fibrillation (AF) with acute decompensated heart failure (ADHF) efficiently."4.12Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment. ( Abe, T; Ebina, T; Hanajima, Y; Hibi, K; Horii, M; Iwahashi, N; Kimura, K; Kimura, Y; Kirigaya, J; Kosuge, M; Matsuzawa, Y; Minamimoto, Y; Okada, K; Takahashi, H; Tamura, K, 2022)
"The HEARTFUL study has demonstrated the efficacy of landiolol, by reducing heart rate or terminating tachycardia, in pediatric patients with supraventricular tachyarrhythmias."4.12Control of Heart Rate in Infant and Child Tachyarrhythmia With Reduced Cardiac Function Using Landiolol (HEARTFUL) - Results of a Prospective, Multicenter, Uncontrolled Clinical Study. ( Aoki, H; Fukunaga, H; Horigome, H; Miura, M; Miyazaki, A; Morishima, E; Ohashi, N; Oki, K; Ono, H; Sagawa, K; Sakaguchi, H; Sato, S; Sumitomo, N; Suzuki, T; Takei, K; Ueda, H, 2022)
" Approximately 6 days after starting intravenous administration of amiodarone (600 mg/day) for maintaining sinus rhythm after cardioversion of AF, electrocardiograms revealed a prolonged QT interval associated with torsade de pointes (TdP)."4.02Suppression of amiodarone-induced torsade de pointes by landiolol in a patient with atrial fibrillation-mediated cardiomyopathy. ( Enomoto, D; Hyodo, T; Ikeda, S; Okura, T; Sakaue, T; Takahashi, K; Takemoto, M; Uemura, S; Utsunomiya, Y; Yamashita, M, 2021)
"Clinical experience with landiolol use in patients with atrial fibrillation (AF) and a severely depressed left ventricular (LV) function is limited."3.96Comparison of Landiolol and Digoxin as an Intravenous Drug for Controlling the Heart Rate in Patients with Atrial Fibrillation and Severely Depressed Left Ventricular Function. ( Akitsu, K; Fujino, T; Ikeda, T; Kinoshita, T; Koike, H; Shinohara, M; Suzuki, T; Wada, R; Yano, K, 2020)
"2%) received landiolol for atrial fibrillation."3.91A prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey. ( Mizutani, H; Nakasu, Y; Sumitani, K; Yamashita, T, 2019)
"The authors assessed the efficacy and safety of landiolol, an ultra-short-acting beta-blocker, with those of amiodarone in the restoration of sinus rhythm for postoperative atrial fibrillation (POAF) in intensive care unit (ICU) patients."3.83Efficacy and Safety of Landiolol Compared to Amiodarone for the Management of Postoperative Atrial Fibrillation in Intensive Care Patients. ( Fujino, Y; Ohta, N; Shibata, SC; Uchiyama, A, 2016)
"Landiolol hydrochloride can be effectively and safely used in patients who develop tachyarrhythmia after esophagectomy."3.80Effect of landiolol hydrochloride on tachyarrhythmia after esophagectomy. ( Fujii, T; Fujiwara, M; Iwata, N; Kobayashi, D; Kodera, Y; Koike, M; Nakayama, G; Niwa, Y; Sugimoto, H; Tanaka, C, 2014)
"The purpose of this study was to find a safe dosing regimen for landiolol, an ultra-short-acting β-adrenergic blocking agent, to rapidly control supraventricular tachyarrhythmias (SVTs) in patients with heart failure (HF)."3.80Novel use of the ultra-short-acting intravenous β1-selective blocker landiolol for supraventricular tachyarrhythmias in patients with congestive heart failure. ( Adachi, T; Aonuma, K; Baba, M; Hasegawa, T; Hiraya, D; Hoshi, T; Kuroki, K; Sato, A, 2014)
"continuous administration of landiolol at a low dose after off-pump coronary artery bypass reduced the incidence of atrial fibrillation."3.79Effect of landiolol hydrochloride after off-pump coronary artery bypass. ( Ishitoya, H; Maisawa, K; Shimamura, Y; Yamazaki, K, 2013)
"The response to continuous intravenous infusion of landiolol was evaluated in 25 patients who developed post-operative atrial fibrillation or atrial flutter after major pulmonary resection."3.78Effect of landiolol hydrochloride, an ultra-short-acting beta 1-selective blocker, on supraventricular tachycardia, atrial fibrillation and flutter after pulmonary resection. ( Ibe, T; Kamiyoshihara, M; Kawashima, O; Nagashima, T; Nakano, T; Shimizu, K; Takeyoshi, I, 2012)
"Low-dose landiolol can be effective quickly and used safely in patients who develop atrial fibrillation after pulmonary resection for lung cancer."3.77Efficacy of low-dose landiolol, an ultrashort-acting β-blocker, on postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer. ( Funakoshi, Y; Maeda, H; Maekura, R; Nojiri, T; Okumura, M; Takeuchi, Y; Yamamoto, K, 2011)
"Intra-operative low-dose infusion of landiolol hydrochloride decreases the incidence of postoperative atrial fibrillation after OPCAB."3.76[Effect of intra-operative low-dose infusion of landiolol hydrochloride on post-operative atrial fibrillation after off-pump coronary artery bypass grafting]. ( Kurosawa, H; Sato, Y; Seto, Y; Takase, S; Wakamatsu, H; Yokoyama, H, 2010)
"Intraoperative and perioperative administration of low-dose landiolol has a preventive effect on the appearance of atrial fibrillation after CABG surgery."3.75Effect of low-dose landiolol, an ultrashort-acting beta-blocker, on postoperative atrial fibrillation after CABG surgery. ( Fujiwara, H; Kawamura, T; Namai, A; Sakurai, M, 2009)
"The purpose of this study was to investigate the efficacy of landiolol hydrochloride, a short-acting beta(1) blocker, by initiating its administration at a low dose (5 microg kg(-1) min(-1)) in patients with postoperative supraventricular arrhythmia."3.75Postoperative administration of landiolol hydrochloride for patients with supraventricular arrhythmia: the efficacy of sustained intravenous infusion at a low dose. ( Fukutomi, T; Nishimori, H; Radhakrishnan, G; Sasaguri, S; Wariishi, S; Yamamoto, M; Yamashita, K, 2009)
"Postoperative treatment with carvedilol following landiolol has the effect of preventing tachycardia during AF after coronary artery bypass grafting."3.75Postoperative treatment of carvedilol following low dose landiolol has preventive effect for atrial fibrillation after coronary artery bypass grafting. ( Kawamura, T; Namai, A; Sakurai, M; Yoshioka, I, 2009)
"We examined the effect of landiolol hydrochloride, a selective beta1-adrenoreceptor antagonist, on the incidence of atrial fibrillation(AF)."3.74[Use of landiolol hydrochloride for the prevention of atrial fibrillation after lung resection]. ( Ishimura, N; Kumano, H; Morioka, M; Nishiwada, M; Okita, T; Shinjo, T; Uji, M, 2008)
" During the intraoperative discrepancy between heart rate and pulse rate, continuous infusion of low dose landiolol was useful to control his heart rate of atrial fibrillation."3.73[Effect of landiolol on heart rate control of atrial fibrillation in a patient with sick sinus syndrome under ventricular pacing]. ( Kitoh, T; Kobayashi, K; Otagiri, T; Satoh, N, 2006)
"Landiolol is a recently innovated ultra-short-acting beta-blocker with 251-fold β1/β2 selectivity, which was originally indicated only to control peri-operative supra-ventricular tachyarrhythmia by 2013 in Japan."2.66Novel rate control strategy with landiolol in patients with cardiac dysfunction and atrial fibrillation. ( Imamura, T; Kinugawa, K, 2020)
"Landiolol is an ultra-short acting beta-blocker, and some randomized controlled trials of landiolol administration for the prevention of POAF have been conducted in Japan."2.50Perioperative landiolol administration reduces atrial fibrillation after cardiac surgery: A meta-analysis of randomized controlled trials. ( Hamasaki, T; Kitakaze, M; Sakamoto, A, 2014)
"Landiolol is an intravenous, selective beta-1-receptor blocking agent with rapid onset of action and ultra-short half-life that has a predominant negative chronotropic and only mild negative inotropic effect without significant reduction of blood pressure."1.72The application of landiolol in the cardiovascular and intensive care ( Fejér, C; Gellér, L; Kiss, B; Kovács, E; Merkely, B; Pilecky, D; Radics, P; Ruzsa, Z; Straub, É; Zima, E, 2022)
" No adverse effects were reported in any patient."1.62Safety and Efficacy of Landiolol Hydrochloride in Children with Tachyarrhythmia of Various Etiologies. ( Ashida, A; Kishi, K; Konishi, H; Nemoto, S; Odanaka, Y; Ozaki, N, 2021)
"Landiolol was ineffective in the majority of AFl/AT patients."1.51Differential Effectiveness of Landiolol Between Atrial Fibrillation and Atrial Flutter/Atrial Tachycardia Patients With Left Ventricular Dysfunction. ( Fujimoto, Y; Hayashi, H; Hayashi, M; Ito-Hagiwara, K; Iwasaki, YK; Maru, E; Oka, E; Shimizu, W; Yamamoto, T; Yodogawa, K, 2019)
"Thyroid storm is a life-threatening disorder that remains a therapeutic challenge."1.46Switching Therapy from Intravenous Landiolol to Transdermal Bisoprolol in a Patient with Thyroid Storm Complicated by Decompensated Heart Failure and Gastrointestinal Dysfunction. ( Fujita, M; Godo, S; Kawazoe, Y; Kudo, D; Kushimoto, S; Nomura, R; Ozaki, H; Shimokawa, H, 2017)
"The bisoprolol patch was introduced 88 h after the start of landiolol administration, when the rate was approximately 3 μg/kg/min."1.43Switching therapy from intravenous beta blocker to bisoprolol transdermal patch for atrial fibrillation tachycardia. ( Doi, K; Hiruma, T; Inokuchi, R; Nakajima, S; Nakamura, K; Tokunaga, K, 2016)
"The patient was a 20-year old male with dilated cardiomyopathy."1.42An Experience of Landiolol Use for an Advanced Heart Failure Patient With Severe Hypotension. ( Amiya, E; Endo, M; Hatano, M; Imamura, T; Inaba, T; Kinugawa, K; Komuro, I; Maki, H; Nitta, D, 2015)
"Landiolol hydrochloride was the first-line treatment in 46 patients and the only therapy in 26 patients."1.39Efficacy of landiolol hydrochloride for atrial fibrillation after open heart surgery. ( Fukushima, S; Kuratani, T; Miyagawa, S; Nishi, H; Saito, S; Sakaguchi, T; Sawa, Y; Ueno, T; Yoshikawa, Y, 2013)
"Landiolol hydrochloride is a new β-adrenergic blocker with a pharmacological profile that suggests it can be administered safely to patients who have sinus tachycardia or tachyarrhythmia and who require heart rate reduction."1.39Postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting or cardiac valve surgery: intraoperative use of landiolol. ( Kim, C; Kohda, S; Nakanishi, K; Sakamoto, A; Takeda, S, 2013)
"When landiolol was administered, enough attention should be paid to the patients whose left ventricular function was low."1.36[Clinical analysis of precaution against atrial fibrillation following cardiac surgery: landiolol or amiodarone?]. ( Abe, T; Fukuda, T; Haruna, T; Inoko, M; Ito, H; Miyamoto, S; Nakane, E; Nohara, R; Sasaki, K; Uehara, K; Ueyama, K, 2010)
"Landiolol hydrochloride was administered continuously until the morning of the following day and sinus rhythm was maintained postoperatively."1.36Conversion of atrial flutter to sinus rhythm during landiolol infusion. ( Goto, K; Noguchi, T; Ohchi, Y; Shingu, C; Yamamoto, S; Yasuda, N, 2010)
"Landiolol is a short-acting beta-blocker, with high beta 1-selectivity and a short duration of action."1.35Clinical role and efficacy of landiolol in the intensive care unit. ( Akada, S; Hongo, T; Miyagi, Y; Sakamoto, A; Sato, C; Takeda, S; Tanaka, K; Terajima, K; Yoshida, Y, 2008)
"A 71-year-old woman with a history of persistent atrial fibrillation underwent clipping of a ruptured cerebral artery aneurysm."1.32Conversion of atrial fibrillation to sinus rhythm during landiolol infusion. ( Goto, M; Isomine, S; Kanazawa, T; Mayahara, T; Nakajima, H; Sakaida, K; Sato, M, 2004)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.10)18.7374
1990's1 (1.10)18.2507
2000's15 (16.48)29.6817
2010's55 (60.44)24.3611
2020's19 (20.88)2.80

Authors

AuthorsStudies
Iwahashi, N1
Kirigaya, J1
Abe, T2
Horii, M1
Takahashi, H1
Hanajima, Y1
Kimura, Y1
Minamimoto, Y1
Okada, K1
Matsuzawa, Y1
Hibi, K1
Kosuge, M1
Ebina, T1
Tamura, K2
Kimura, K1
Radics, P1
Kiss, B1
Kovács, E1
Pilecky, D1
Ruzsa, Z1
Straub, É1
Fejér, C1
Gellér, L1
Merkely, B1
Zima, E1
Solomon, SD1
Claggett, BL1
Miao, ZM1
Diaz, R1
Felker, GM1
McMurray, JJV1
Metra, M1
Corbalan, R1
Filippatos, G1
Goudev, AR1
Mareev, V1
Serpytis, P1
Suter, T1
Yilmaz, MB1
Zannad, F1
Kupfer, S1
Heitner, SB1
Malik, FI1
Teerlink, JR1
Ferraris, A2
Jacquet-Lagrèze, M2
Cazenave, L2
Fornier, W2
Jalalzai, W2
Rousseau-Saine, N2
Pozzi, M2
Fellahi, JL2
van der Meer, P1
Rienstra, M2
van Veldhuisen, DJ1
Sagawa, K2
Suzuki, T4
Takei, K1
Miura, M2
Ueda, H2
Horigome, H2
Ono, H2
Ohashi, N2
Sato, S1
Fukunaga, H1
Aoki, H1
Miyazaki, A2
Sakaguchi, H2
Morishima, E1
Oki, K1
Sumitomo, N2
Wang, W2
Gao, F2
He, X2
Gao, Y3
Shi, L1
Liu, W2
Zhuang, X1
Kawakami, A1
Kobayashi, Y1
Katsube, T1
Gassanov, N1
Er, F1
Stix, G1
Wolzt, M1
Domanovits, H1
Kadlecová, P1
Husch, B1
Trebs, M1
Hodisch, J1
Unger, M1
Krumpl, G1
Walter, E1
Heringlake, M1
O'Brien, B1
Muehlschlegel, JD1
Sasaki, K2
Kumagai, K1
Maeda, K2
Akiyama, M1
Ito, K1
Matsuo, S1
Katahira, S1
Suzuki, Y2
Kaiho, Y1
Sugawara, Y1
Tsuji, I1
Saiki, Y1
Imamura, T3
Kinugawa, K3
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q1
Wang, J4
Zhang, E1
Zhang, J4
Li, Y5
Xue, F1
Deng, L1
Liu, L3
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J3
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y5
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
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Validad, MH1
Langroudi, FH1
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Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
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Nordfalk, KF1
Nordahl, SHG1
Inoue, T1
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
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Johnson, ML1
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Weinstock, RS1
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Buscagan, TM1
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Toy, W1
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Hudis, CA1
Norton, L1
Nagy, RJ1
Odegaard, JI1
Lanman, RB1
Solit, DB1
Robson, ME1
Lacouture, ME1
Brogi, E1
Reis-Filho, JS1
Moynahan, ME1
Scaltriti, M1
Chandarlapaty, S1
Papouskova, K1
Moravcova, M1
Masrati, G1
Ben-Tal, N1
Sychrova, H1
Zimmermannova, O1
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Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects With Chronic Heart Failure With Reduced Ejection Fraction (GALACTIC-HF)[NCT02929329]Phase 38,256 participants (Actual)Interventional2017-01-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Kansas City Cardiomyopathy Questionnaire Total Symptom Score (KCCQ TSS) at Week 24

"The Kansas City Cardiomyopathy Questionnaire is a self-administered questionnaire with a 2-week recall period that includes 23 items that map to 7 domains: symptom frequency; symptom burden; symptom stability; physical limitations; social limitations; quality of life; and self-efficacy (the patient's understanding of how to manage their heart failure). The symptom frequency and symptom burden domains are merged into a total symptom score. Scores are represented on a 0-to-100-point scale, where lower scores represent more frequent and severe symptoms and scores of 100 indicate no symptoms.~The change from baseline in KCCQ TSS was analyzed separately for each randomization setting (inpatient and outpatient).~Least squares means are from the mixed model which includes baseline total symptom score value, region, baseline eGFR, scheduled visit, treatment group and interaction of treatment with scheduled visit as covariates." (NCT02929329)
Timeframe: Baseline and Week 24

Interventionscores on a scale (Least Squares Mean)
Placebo: Oupatients6.29
Omecamtiv Mecarbil: Outpatients5.83
Placebo: Inpatients21.15
Omecamtiv Mecarbil: Inpatients23.65

Time to All-cause Death

"All events were adjudicated by an independent external clinical-events committee at the Duke Clinical Research Institute, using standardized definitions based on the recent ACC/AHA standards for endpoint definitions in cardiovascular clinical trials.~Time to all-cause death was analyzed using Kaplan-Meier methods. Since the median was not calculated, the percentage of participants with an event are reported. Events that occurred up to the earliest of last confirmed survival status date or analysis cut-off date (07 August 2020) are included." (NCT02929329)
Timeframe: From randomization up to earliest of last confirmed survival status date or analysis cut-off date (07 August 2020); the overall median duration of follow-up was 21.8 months up to a maximum of 42 months.

Interventionpercentage of participants (Number)
Placebo25.9
Omecamtiv Mecarbil25.9

Time to Cardiovascular Death

"Cardiovascular death includes acute myocardial infarction (MI), sudden cardiac death, death due to heart failure, death due to stroke, death due to cardiovascular (CV) procedures, death due to CV hemorrhage, and death due to other CV causes.~All deaths were adjudicated by an independent external clinical-events committee at the Duke Clinical Research Institute, using standardized definitions based on the recent ACC/AHA standards for endpoint definitions in cardiovascular clinical trials.~Time to cardiovascular death was analyzed using Kaplan-Meier methods. Since the median was not calculated, the percentage of participants with a positively adjudicated event during the study is reported." (NCT02929329)
Timeframe: From randomization to up to earliest of last confirmed survival status date or analysis cut-off date (07 August 2020); the overall median duration of follow-up was 21.8 months up to a maximum of 42 months.

Interventionpercentage of participants (Number)
Placebo19.4
Omecamtiv Mecarbil19.6

Time to Cardiovascular Death or First Heart Failure Event

"The primary outcome was a composite of a heart-failure (HF) event or cardiovascular (CV) death, whichever occurred first, in a time-to-event analysis.~A heart-failure event was defined as an urgent clinic visit, emergency department visit, or hospitalization for subjectively and objectively worsening heart failure leading to treatment intensification beyond a change in oral diuretic therapy.~All deaths and HF events were adjudicated by an independent external clinical events committee (CEC) at the Duke Clinical Research Institute, using standardized definitions based on the recent American College of Cardiology/American Heart Association (ACC/AHA) standards for endpoint definitions in cardiovascular clinical trials.~Time to cardiovascular death or first HF event was analyzed using Kaplan-Meier (KM) methods. Since the median was not calculated, the percentage of participants with a positively adjudicated event during the study is reported." (NCT02929329)
Timeframe: From randomization to up to earliest of last confirmed survival status date or analysis cut-off date (07 August 2020); the overall median duration of follow-up was 21.8 months up to a maximum of 42 months.

Interventionpercentage of participants (Number)
Placebo39.1
Omecamtiv Mecarbil37.0

Time to First Heart Failure Hospitalization

"A HF hospitalization is defined as an event that met all of the following criteria:~The participant was admitted to the hospital with a primary diagnosis of HF;~The length of stay in the hospital extended for at least 24 hours;~The participant exhibited documented new or worsening symptoms due to HF on presentation;~The participant had objective evidence of new or worsening HF;~The participant received initiation or intensification of treatment specifically for HF, including an intravenous diuretic or vasoactive agent, mechanical or surgical intervention, or mechanical fluid removal.~Events were adjudicated by an independent external CEC at the Duke Clinical Research Institute using standardized definitions based on the ACC/AHA standards for endpoint definitions in CV clinical trials.~Time to first HF hospitalization was analyzed using KM methods. Since the median was not calculated, the percentage of participants with a positively adjudicated event is reported." (NCT02929329)
Timeframe: From randomization to up to earliest of last confirmed survival status date or analysis cut-off date (07 August 2020); the overall median duration of follow-up was 21.8 months up to a maximum of 42 months.

Interventionpercentage of participants (Number)
Placebo28.7
Omecamtiv Mecarbil27.7

Reviews

11 reviews available for urea and Auricular Fibrillation

ArticleYear
[The Role of Ultrarapid Acting Betablocker Esmolol and Landiolol in Critically Ill Patients].
    Deutsche medizinische Wochenschrift (1946), 2019, Volume: 144, Issue:18

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Critical Illness; Humans; Morpholines; Propanolami

2019
Cost-Effectiveness Analysis of Landiolol, an Ultrashort-Acting Beta-Blocker, for Prevention of Postoperative Atrial Fibrillation for the Germany Health Care System.
    Journal of cardiothoracic and vascular anesthesia, 2020, Volume: 34, Issue:4

    Topics: Atrial Fibrillation; Cost-Benefit Analysis; Delivery of Health Care; Germany; Humans; Morpholines; P

2020
Novel rate control strategy with landiolol in patients with cardiac dysfunction and atrial fibrillation.
    ESC heart failure, 2020, Volume: 7, Issue:5

    Topics: Atrial Fibrillation; Humans; Japan; Morpholines; Urea

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Beta-Blocker Landiolol Hydrochloride in Preventing Atrial Fibrillation Following Cardiothoracic Surgery: A Systematic Review and Meta-Analysis.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2022, Feb-20, Volume: 28, Issue:1

    Topics: Atrial Fibrillation; Humans; Morpholines; Postoperative Complications; Treatment Outcome; Urea

2022
Prevention of atrial fibrillation after cardiac surgery using low-dose landiolol: A systematic review and meta-analysis.
    Journal of clinical anesthesia, 2017, Volume: 42

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Do

2017
Landiolol: A Review in Tachyarrhythmias.
    Drugs, 2018, Volume: 78, Issue:3

    Topics: Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Atrial Fibrillation; Dose-Respo

2018
Landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery: a meta-analysis.
    Pacing and clinical electrophysiology : PACE, 2014, Volume: 37, Issue:6

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Humans; Incidence; Morphol

2014
Perioperative landiolol administration reduces atrial fibrillation after cardiac surgery: A meta-analysis of randomized controlled trials.
    Advances in therapy, 2014, Volume: 31, Issue:4

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cardiac Surgical Procedures; Humans; Incidence; Ja

2014
Are beta-blockers effective for preventing post-coronary artery bypass grafting atrial fibrillation? Direct and network meta-analyses.
    Irish journal of medical science, 2016, Volume: 185, Issue:2

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Bayes Theorem; Bisoprolol; Coronary Artery Bypass;

2016
Could atrial natriuretic peptide be a useful drug therapy for high-risk patients after cardiac surgery?
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 8, Issue:4

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Natriuretic Factor; Benchmarking; Cardiac Surgic

2009

Trials

21 trials available for urea and Auricular Fibrillation

ArticleYear
Influence of atrial fibrillation on efficacy and safety of omecamtiv mecarbil in heart failure: the GALACTIC-HF trial.
    European heart journal, 2022, 06-14, Volume: 43, Issue:23

    Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Heart Failure; Humans; Quality of Life; Stroke Volume;

2022
Effects of Landiolol on Macrocirculatory Parameters and Left and Right Ventricular Performances Following Cardiac Surgery: A Randomized Controlled Trial.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:8 Pt B

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cardiac Surgical Procedures; Humans; Morpholines;

2022
Open-Label Two-Dose Pilot Study of Landiolol for the Treatment of Atrial Fibrillation/Atrial Flutter in Caucasian Patients.
    Circulation journal : official journal of the Japanese Circulation Society, 2019, 12-25, Volume: 84, Issue:1

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Humans; Middle Aged; Morpholines; Pilo

2019
Preventive effect of low-dose landiolol on postoperative atrial fibrillation study (PELTA study).
    General thoracic and cardiovascular surgery, 2020, Volume: 68, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atrial Fibrillation; Cardiovascular Surgical P

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Microcirculatory effects of landiolol: a double-blind, randomised, controlled study after cardiac surgery.
    British journal of anaesthesia, 2021, Volume: 126, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedure

2021
The suppressive effects of landiolol administration on the occurrence of postoperative atrial fibrillation and tachycardia, and plasma IL-6 elevation in patients undergoing esophageal surgery: A randomized controlled clinical trial.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cytokines; Esophagea

2017
Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer.
    The British journal of surgery, 2017, Volume: 104, Issue:8

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Carcinoma, Squ

2017
Prevention of atrial fibrillation with ultra-low dose landiolol after off-pump coronary artery bypass grafting.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2014, Volume: 20, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribut

2014
Perioperative use of a beta blocker in coronary artery bypass grafting.
    Asian cardiovascular & thoracic annals, 2013, Volume: 21, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Atrial Fibrilla

2013
Impacts of patient characteristics on the effectiveness of landiolol in AF/AFL patients complicated with LV dysfunction: Subgroup analysis of the J-Land study.
    Advances in therapy, 2014, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Digoxin; Drug

2014
Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction: Prevention of Atrial Fibrillation After Cardiac Surgery With Landiolol Hydrochloride for Left Ventric
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 150, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; F

2015
Landiolol infusion during general anesthesia does not prevent postoperative atrial fibrillation in patients undergoing lung resection.
    General thoracic and cardiovascular surgery, 2016, Volume: 64, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Anesthesia, General; Atrial Fibrillation; Dose-Response Relations

2016
Study design for control of HEART rate in inFant and child tachyarrhythmia with heart failure Using Landiolol (HEARTFUL): A prospective, multicenter, uncontrolled clinical trial.
    Journal of cardiology, 2017, Volume: 70, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschoo

2017
Landiolol hydrochloride for prevention of atrial fibrillation after coronary artery bypass grafting: new evidence from the PASCAL trial.
    The Journal of thoracic and cardiovascular surgery, 2011, Volume: 141, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypa

2011
Effect of postoperative landiolol administration for atrial fibrillation after off pump coronary artery bypass surgery.
    The Journal of cardiovascular surgery, 2012, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Coronary Artery Bypass, Off-Pump; Coronary A

2012
Landiolol, an ultra-short-acting β₁-blocker, more effectively terminates atrial fibrillation than diltiazem after open heart surgery: prospective, multicenter, randomized, open-label study (JL-KNIGHT study).
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Cardiac Surgical P

2012
Feasibility of landiolol and bisoprolol for prevention of atrial fibrillation after coronary artery bypass grafting: a pilot study.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:5

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents;

2012
Safety and efficacy of an ultrashort-acting β1-blocker on left ventricular dysfunction.
    The heart surgery forum, 2012, Volume: 15, Issue:4

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Do

2012
Efficacy of landiolol hydrochloride for prevention of atrial fibrillation after heart valve surgery.
    International heart journal, 2012, Volume: 53, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Drug; Female; Follow-

2012
Pharmacokinetics of landiolol hydrochloride, a new ultra-short-acting beta-blocker, in patients with cardiac arrhythmias.
    Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; D

2000

Other Studies

60 other studies available for urea and Auricular Fibrillation

ArticleYear
Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment.
    Journal of cardiology, 2022, Volume: 79, Issue:1

    Topics: Atrial Fibrillation; Heart Failure; Hospital Mortality; Humans; Morpholines; Prognosis; Prospective

2022
The application of landiolol in the cardiovascular and intensive care
    Orvosi hetilap, 2022, 01-09, Volume: 163, Issue:2

    Topics: Atrial Fibrillation; Critical Care; Heart Rate; Humans; Morpholines; Myocardial Infarction; Urea

2022
A deleterious interaction between omecamtiv mecarbil and atrial fibrillation in patients with heart failure: an influence of digoxin?
    European heart journal, 2022, 06-14, Volume: 43, Issue:23

    Topics: Atrial Fibrillation; Digoxin; Heart Failure; Humans; Urea

2022
Control of Heart Rate in Infant and Child Tachyarrhythmia With Reduced Cardiac Function Using Landiolol (HEARTFUL) - Results of a Prospective, Multicenter, Uncontrolled Clinical Study.
    Circulation journal : official journal of the Japanese Circulation Society, 2022, 12-23, Volume: 87, Issue:1

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Child; Heart Rate; Humans; Hypotension; Infant; Pr

2022
Efficacy of tolvaptan in postoperative volume therapy for acute Stanford type A aortic dissection.
    BMC cardiovascular disorders, 2023, 02-21, Volume: 23, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Aortic Dissection; Atrial Fibrillation; Diuretics; Humans

2023
[Effect of Landiolol for Atrial Fibrillation after Open Heart Surgery].
    Kyobu geka. The Japanese journal of thoracic surgery, 2023, Volume: 76, Issue:5

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cardiac Surgical Procedures; Female; Humans; Male;

2023
A Penny Saved Should Be a Penny Earned.
    Journal of cardiothoracic and vascular anesthesia, 2020, Volume: 34, Issue:4

    Topics: Atrial Fibrillation; Cost-Benefit Analysis; Germany; Humans; Morpholines; Urea

2020
Comparison of Landiolol and Digoxin as an Intravenous Drug for Controlling the Heart Rate in Patients with Atrial Fibrillation and Severely Depressed Left Ventricular Function.
    International heart journal, 2020, Sep-29, Volume: 61, Issue:5

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; B

2020
Rate control in atrial fibrillation using Landiolol is safe in critically ill Covid-19 patients.
    Critical care (London, England), 2021, 01-22, Volume: 25, Issue:1

    Topics: Aged; Atrial Fibrillation; COVID-19 Drug Treatment; Critical Illness; Female; Heart Rate; Hospitaliz

2021
Suppression of amiodarone-induced torsade de pointes by landiolol in a patient with atrial fibrillation-mediated cardiomyopathy.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2021, Volume: 26, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathies; Electrocardiography

2021
Safety and Efficacy of Landiolol Hydrochloride in Children with Tachyarrhythmia of Various Etiologies.
    Pediatric cardiology, 2021, Volume: 42, Issue:8

    Topics: Atrial Fibrillation; Child; Humans; Infant; Morpholines; Retrospective Studies; Tachycardia; Urea

2021
Switching Therapy from Intravenous Landiolol to Transdermal Bisoprolol in a Patient with Thyroid Storm Complicated by Decompensated Heart Failure and Gastrointestinal Dysfunction.
    Internal medicine (Tokyo, Japan), 2017, Oct-01, Volume: 56, Issue:19

    Topics: Administration, Cutaneous; Administration, Intravenous; Adrenergic beta-Antagonists; Adult; Atrial F

2017
[Postoperative Atrial Fibrillation in Patients who Underwent Thoracic Aortic Surgery].
    Kyobu geka. The Japanese journal of thoracic surgery, 2018, Volume: 71, Issue:2

    Topics: Aged; Aged, 80 and over; Aorta, Thoracic; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Mo

2018
Landiolol hydrochloride for preventing postoperative atrial fibrillation.
    Anaesthesia, 2018, Volume: 73, Issue:7

    Topics: Atrial Fibrillation; Humans; Incidence; Morpholines; Risk Factors; Urea

2018
Differential Effectiveness of Landiolol Between Atrial Fibrillation and Atrial Flutter/Atrial Tachycardia Patients With Left Ventricular Dysfunction.
    Circulation journal : official journal of the Japanese Circulation Society, 2019, 03-25, Volume: 83, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Humans; Male; Middle Aged; Morpho

2019
What Determines the Response to Landiolol?
    Circulation journal : official journal of the Japanese Circulation Society, 2019, 06-25, Volume: 83, Issue:7

    Topics: Atrial Fibrillation; Atrial Flutter; Humans; Morpholines; Tachycardia; Urea; Ventricular Dysfunction

2019
What Determines the Response to Landiolol? - Reply.
    Circulation journal : official journal of the Japanese Circulation Society, 2019, 06-25, Volume: 83, Issue:7

    Topics: Atrial Fibrillation; Atrial Flutter; Humans; Morpholines; Tachycardia; Urea; Ventricular Dysfunction

2019
A prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey.
    Journal of cardiology, 2019, Volume: 74, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Female; Hea

2019
Atrial fibrillation after esophageal cancer surgery: an analysis of 207 consecutive patients.
    Surgery today, 2014, Volume: 44, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Colon; Esophageal

2014
Novel use of the ultra-short-acting intravenous β1-selective blocker landiolol for supraventricular tachyarrhythmias in patients with congestive heart failure.
    Heart and vessels, 2014, Volume: 29, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Atrial Fibrillation; Blood Pressure; Drug Administrati

2014
A low-dose β1-blocker effectively and safely slows the heart rate in patients with acute decompensated heart failure and rapid atrial fibrillation.
    Cardiology, 2014, Volume: 127, Issue:2

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Female; Heart Failure; Heart

2014
Effect of landiolol hydrochloride after off-pump coronary artery bypass.
    Asian cardiovascular & thoracic annals, 2013, Volume: 21, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypa

2013
The role of β-blockers in cardiac perioperative management.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2014, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Dr

2014
Preventive effect of intraoperative landiolol administration on atrial fibrillation after off-pump coronary artery bypass grafting.
    Advances in therapy, 2014, Volume: 31, Issue:10

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Coronary Artery Bypass, O

2014
Effect of landiolol hydrochloride on tachyarrhythmia after esophagectomy.
    Hepato-gastroenterology, 2014, Volume: 61, Issue:134

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium C

2014
Design of a prospective observational survey on landiolol in atrial fibrillation/atrial flutter patients with chronic heart failure - AF-CHF landiolol survey.
    Journal of cardiology, 2015, Volume: 66, Issue:1

    Topics: Adrenergic beta-Antagonists; Adverse Drug Reaction Reporting Systems; Aged; Atrial Fibrillation; Atr

2015
Thyroid Storm with Heart Failure Treated with a Short-acting Beta-adrenoreceptor Blocker, Landiolol Hydrochloride.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Electric Countershock; Female; Heart Failure

2015
Might a beta blocker finally provide some relief from postoperative atrial fibrillation?
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 150, Issue:4

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Morpholines; Postoperative Compli

2015
An Experience of Landiolol Use for an Advanced Heart Failure Patient With Severe Hypotension.
    International heart journal, 2015, Volume: 56, Issue:5

    Topics: Adrenergic beta-1 Receptor Antagonists; Atrial Fibrillation; Biological Availability; Cardiomyopathy

2015
Efficacy and Safety of Landiolol Compared to Amiodarone for the Management of Postoperative Atrial Fibrillation in Intensive Care Patients.
    Journal of cardiothoracic and vascular anesthesia, 2016, Volume: 30, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Critical Care; Female; Humans; Male;

2016
Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.
    Cardiovascular research, 2016, 06-01, Volume: 110, Issue:3

    Topics: Animals; Aspirin; Atrial Fibrillation; Bleeding Time; Carotid Artery Diseases; Case-Control Studies;

2016
Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.
    European heart journal, 2017, 01-01, Volume: 38, Issue:1

    Topics: Analysis of Variance; Animals; Antithrombins; Atrial Fibrillation; Cell Proliferation; Dabigatran; F

2017
Alteration of fatal 1:1 conducted atrial flutter to less conducted ratio by landiolol infusion.
    Journal of anesthesia, 2016, Volume: 30, Issue:4

    Topics: Aged, 80 and over; Atrial Fibrillation; Atrial Flutter; Electrocardiography; Humans; Male; Morpholin

2016
Switching therapy from intravenous beta blocker to bisoprolol transdermal patch for atrial fibrillation tachycardia.
    Journal of anesthesia, 2016, Volume: 30, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; B

2016
Prognostic indices among hypertensive heart failure patients in Nigeria: the roles of 24-hour Holter electrocardiography and 6-minute walk test.
    Vascular health and risk management, 2017, Volume: 13

    Topics: Aged; Atrial Fibrillation; Biomarkers; Chi-Square Distribution; Echocardiography, Doppler; Electroca

2017
Use of landiolol for treatment of atrial fibrillation in a patient with terminal cancer.
    The Journal of emergency medicine, 2010, Volume: 38, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Colonic Neoplasms; Female; Humans; Morpholines; T

2010
[Use of landiolol hydrochloride for the prevention of atrial fibrillation after lung resection].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male

2008
Effect of low-dose landiolol, an ultrashort-acting beta-blocker, on postoperative atrial fibrillation after CABG surgery.
    General thoracic and cardiovascular surgery, 2009, Volume: 57, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiopulmonary Bypa

2009
Postoperative administration of landiolol hydrochloride for patients with supraventricular arrhythmia: the efficacy of sustained intravenous infusion at a low dose.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:5

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over;

2009
Postoperative treatment of carvedilol following low dose landiolol has preventive effect for atrial fibrillation after coronary artery bypass grafting.
    The Thoracic and cardiovascular surgeon, 2009, Volume: 57, Issue:8

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Carbazoles; Carvedilol; Coronary Artery Bypass; Fe

2009
Conversion of atrial flutter to sinus rhythm during landiolol infusion.
    Journal of anesthesia, 2010, Volume: 24, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Hernia, Inguinal; Humans; Infusions, Intravenous;

2010
[Effects of landiolol on hemodynamic improvement and prevention of atrial fibrillation in the perioperative period of off-pump coronary artery bypass grafting].
    Kyobu geka. The Japanese journal of thoracic surgery, 2010, Volume: 63, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Coronary Artery Bypass, Off-Pump; Female; He

2010
[Clinical analysis of precaution against atrial fibrillation following cardiac surgery: landiolol or amiodarone?].
    Kyobu geka. The Japanese journal of thoracic surgery, 2010, Volume: 63, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac

2010
[Effect of intra-operative low-dose infusion of landiolol hydrochloride on post-operative atrial fibrillation after off-pump coronary artery bypass grafting].
    Kyobu geka. The Japanese journal of thoracic surgery, 2010, Volume: 63, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Coronary Artery Bypass, Off-Pump; Female; Hu

2010
Effect of landiolol hydrochloride, an ultra-short-acting beta 1-selective blocker, on supraventricular tachycardia, atrial fibrillation and flutter after pulmonary resection.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutter

2012
Efficacy of low-dose landiolol, an ultrashort-acting β-blocker, on postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer.
    General thoracic and cardiovascular surgery, 2011, Volume: 59, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Female; Hemodynamics; Humans; Infusions, Int

2011
Intravenous infusion of ultra-short-acting β-blocker for postoperative atrial fibrillation is the one of choice.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:5

    Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Cardiac Surgical Procedures; Cardiovascular Agents

2012
Efficacy of landiolol hydrochloride for atrial fibrillation after open heart surgery.
    Heart and vessels, 2013, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; B

2013
Postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting or cardiac valve surgery: intraoperative use of landiolol.
    Journal of cardiothoracic surgery, 2013, Jan-24, Volume: 8

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Heart Valve Prosthesis Im

2013
[Successful control of rapid heart rate in a patient with atrial fibrillation by continuous intravenous administration of landiolol hydrochloride].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Infusions, Intravenous; Male; Morpholines

2003
[Clinical experience of landiolol for the treatment of intraoperative rapid atrial fibrillation].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Cardiopulmonary Bypass; Cardiovascular Surgi

2004
[Perioperative heart rate control with landiolol for a patient with rapid atrial fibrillation complicated with low cardiac function].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:5

    Topics: Anesthesia, Epidural; Anesthesia, General; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardi

2004
Acute renal embolism. Forty-four cases of renal infarction in patients with atrial fibrillation.
    Medicine, 2004, Volume: 83, Issue:5

    Topics: Acute Disease; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Biomarkers; Creatinine;

2004
Conversion of atrial fibrillation to sinus rhythm during landiolol infusion.
    Journal of anesthesia, 2004, Volume: 18, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Infusions, Intravenous; Intracran

2004
Successful management of tachycardiac atrial fibrillation in a septic patient with landiolol.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Hemodynamics; Humans; Intraoperative Complication

2005
[Effect of landiolol on heart rate control of atrial fibrillation in a patient with sick sinus syndrome under ventricular pacing].
    Masui. The Japanese journal of anesthesiology, 2006, Volume: 55, Issue:9

    Topics: Anesthesia, General; Anti-Asthmatic Agents; Arthroplasty, Replacement; Atrial Fibrillation; Cardiac

2006
Relationship between P-wave dispersion and effective hemodialysis in chronic hemodialysis patients.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2007, Volume: 16, Issue:2

    Topics: Atrial Fibrillation; Creatinine; Electric Impedance; Electrocardiography; Female; Heart Conduction S

2007
Clinical role and efficacy of landiolol in the intensive care unit.
    Journal of anesthesia, 2008, Volume: 22, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Blood Pressure; Catecholamines; Female; Hear

2008
Overfeeding in a patient with Kwashiorkor syndrome.
    Nutrition (Burbank, Los Angeles County, Calif.), 1996, Volume: 12, Issue:9

    Topics: Atrial Fibrillation; Energy Intake; Female; Humans; Hypercapnia; Kwashiorkor; Magnesium Deficiency;

1996
[Blood digoxin level and digitalization].
    Schweizerische medizinische Wochenschrift, 1974, Jan-19, Volume: 104, Issue:3

    Topics: Aged; Atrial Fibrillation; Creatinine; Digoxin; Dose-Response Relationship, Drug; Electrocardiograph

1974