urea has been researched along with Astrocytoma, Grade IV in 31 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our data shown that t-AUCB inhibits cell proliferation, migration and invasion and induces cell cycle G1 phase arrest in vitro but induces no cell apoptosis; increased Hsp27 activation and following COX-2 overexpression confer resistance to t-AUCB treatment in glioblastoma both in vitro and in vivo; quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo." | 7.83 | Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo. ( Fan, Y; Li, J; Li, L; Li, R; Tang, C, 2016) |
| "Herein, we report new quinazoline-urea based compounds with potent cytotoxic activities against TMZ-resistant glioblastoma multiforme (GBM) cells." | 7.81 | Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM). ( Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H, 2015) |
| "Our data shown that t-AUCB inhibits cell proliferation, migration and invasion and induces cell cycle G1 phase arrest in vitro but induces no cell apoptosis; increased Hsp27 activation and following COX-2 overexpression confer resistance to t-AUCB treatment in glioblastoma both in vitro and in vivo; quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo." | 3.83 | Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo. ( Fan, Y; Li, J; Li, L; Li, R; Tang, C, 2016) |
| "Herein, we report new quinazoline-urea based compounds with potent cytotoxic activities against TMZ-resistant glioblastoma multiforme (GBM) cells." | 3.81 | Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM). ( Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (41.94) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Owusu-Ansah, M | 1 |
| Guptan, N | 1 |
| Alindogan, D | 1 |
| Morizono, M | 1 |
| Caldovic, L | 1 |
| Logun, MT | 1 |
| Wynens, KE | 1 |
| Simchick, G | 1 |
| Zhao, W | 1 |
| Mao, L | 1 |
| Zhao, Q | 2 |
| Mukherjee, S | 2 |
| Brat, DJ | 1 |
| Karumbaiah, L | 1 |
| Kovaleva, K | 1 |
| Oleshko, O | 1 |
| Mamontova, E | 1 |
| Yarovaya, O | 1 |
| Zakharova, O | 1 |
| Zakharenko, A | 1 |
| Kononova, A | 1 |
| Dyrkheeva, N | 1 |
| Cheresiz, S | 1 |
| Pokrovsky, A | 1 |
| Lavrik, O | 1 |
| Salakhutdinov, N | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 3 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, J | 12 |
| Li, P | 2 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Hu, W | 3 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 2 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
| Su, X | 1 |
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| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
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| Mi, Y | 1 |
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| Cai, X | 1 |
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| Shi, Y | 1 |
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| Feng, G | 1 |
| Kuang, Y | 1 |
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| Zhu, ZQ | 1 |
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| Celestrin, CP | 1 |
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| Guadagnini, D | 1 |
| Tadelle, RM | 1 |
| Saad, MJA | 1 |
| Oliveira, AG | 1 |
| Bianconi, V | 1 |
| Bronzo, P | 1 |
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| Sahebkar, A | 1 |
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1 review available for urea and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
3 trials available for urea and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
1,3-bis (2-chloroethyl)-1-nitrosourea (NSC-409962) in the treatment of brain tumors.
Topics: Adenocarcinoma; Adolescent; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chordoma; Clinical | 1970 |
Treatment of Hodgkin's disease and other cancers with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962).
Topics: Adenocarcinoma; Adenoma, Islet Cell; Adolescent; Adrenal Gland Neoplasms; Adult; Alkylating Agents; | 1971 |
28 other studies available for urea and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Topics: Adenocarcinoma of Lung; Amino-Acid N-Acetyltransferase; Arginine; Carbamoyl-Phosphate Synthase (Ammo | 2023 |
Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion.
Topics: AC133 Antigen; Animals; Cell Line, Tumor; Cell Movement; Chondroitin Sulfates; Glioblastoma; Glioma; | 2019 |
Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism; | 2019 |
Identification of pimavanserin tartrate as a potent Ca
Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Calcium-Binding Pr | 2021 |
Synthesis and Anticancer Activity of Novel Ureas and Sulfamides Incorporating 1-Aminotetralins.
Topics: Analysis of Variance; Antineoplastic Agents; Cell Death; Cell Line; Cell Line, Tumor; Cell Survival; | 2017 |
Phospho-mTOR expression in human glioblastoma microglia-macrophage cells.
Topics: Adult; Aged; Brain Neoplasms; Cell Line; Cell Line, Tumor; Dinoprostone; Female; Glioblastoma; Human | 2019 |
γ-secretase inhibitor DAPT sensitizes t-AUCB-induced apoptosis of human glioblastoma cells in vitro via blocking the p38 MAPK/MAPKAPK2/Hsp27 pathway.
Topics: Amyloid Precursor Protein Secretases; Apoptosis; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cell | 2014 |
Phosphorylation of AKT induced by phosphorylated Hsp27 confers the apoptosis-resistance in t-AUCB-treated glioblastoma cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Benzoates; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Pr | 2015 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship | 2015 |
Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo.
Topics: Animals; Benzoates; Brain Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Cyclooxygenase 2 | 2016 |
Quercetin blocks t-AUCB-induced autophagy by Hsp27 and Atg7 inhibition in glioblastoma cells in vitro.
Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 7; Benzoates; Brain Neoplasms; Cell Line | 2016 |
A novel histone deacetylase inhibitor, CKD5, has potent anti-cancer effects in glioblastoma.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationshi | 2017 |
In search of druggable targets for GBM amino acid metabolism.
Topics: Amino Acids; Brain Neoplasms; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulat | 2017 |
Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Evaluation, Pr | 2009 |
t-AUCB, an improved sEH inhibitor, suppresses human glioblastoma cell growth by activating NF-κB-p65.
Topics: Apoptosis; Benzoates; Blotting, Western; Brain Neoplasms; Carcinoma, Hepatocellular; Cell Cycle; Cel | 2012 |
The apoptosis-resistance in t-AUCB-treated glioblastoma cells depends on activation of Hsp27.
Topics: Apoptosis; Benzoates; Blotting, Western; Brain Neoplasms; Caspase 3; Cell Proliferation; Enzyme Inhi | 2012 |
Recombinant forms of the neurotrophic factor pigment epithelium-derived factor activate cellular metabolism and inhibit proliferation of the RAW macrophage cell line.
Topics: Animals; Blood Proteins; Brain Neoplasms; Cell Count; Cell Division; Culture Media, Serum-Free; Dose | 2000 |
[Enzyme histochemistry of experimental brain tumours in rabbits].
Topics: Animals; Brain Neoplasms; Esterases; Glioblastoma; Glioma; Glycoside Hydrolases; Histocytochemistry; | 1969 |
[Experimental tumors of the central nervous system].
Topics: Abdominal Neoplasms; Animals; Astrocytoma; Brain Neoplasms; Carcinogens; Central Nervous System; Fem | 1968 |
[Experimental tumors of the central nervous system in rabbits].
Topics: Animals; Astrocytoma; Brain Neoplasms; Female; Glioblastoma; Male; Neoplasms, Experimental; Nitroso | 1968 |
[Induction of brain and spinal cord tumors in rabbits with N-methyl-N-nitrosourea].
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Female; Glioblastoma; Injections, Intravenous; Intesti | 1969 |
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; | 1969 |
Experimental brain tumours in dogs.
Topics: Animals; Brain Neoplasms; Carcinogens; Cerebral Hemorrhage; Corpus Callosum; Dogs; Female; Frontal L | 1970 |
Scintiphotographic evaluation of response of brain neoplasms to systemic chemotherapy.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Ependymoma; Follow-Up Studies; Frontal L | 1971 |
Effect of chemotherapy and-or head irradiation on survival of mice with intracranial glioma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Copper; Cytarabine; Disease Models, Animal; Ependym | 1971 |
Treatment of malignant brain tumors with nitrosoureas.
Topics: Administration, Oral; Astrocytoma; Brain Neoplasms; Glioblastoma; Humans; Nitroso Compounds; Nitroso | 1971 |
Effects of cytosine arabinoside and 1,3-bis(2-chloroethyl)-1-nitrosourea on human glial tumor cells.
Topics: Brain Neoplasms; Cell Count; Cell Line; Cells, Cultured; Cytarabine; Depression, Chemical; Drug Comb | 1972 |
Lack of correlation between clinical and angiographic findings in patients with brain tumors under BCNU chemotherapy.
Topics: Adult; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Cerebral Angiography; Evaluation Studies a | 1972 |