Page last updated: 2024-10-20

urea and Arthritis, Rheumatoid

urea has been researched along with Arthritis, Rheumatoid in 41 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research Excerpts

ExcerptRelevanceReference
"A double-blind cross-over study using a double placebo technique was employed to compare the effectiveness of daily alclofenac 3 g and phenylbutazone 300 mg in rheumatoid arthritis."9.04A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis. ( Chamberlain, MA; Wright, V, 1975)
"Telmisartan improved anemia and arthritis parameters and showed anti-inflammatory and reno-protective effects, in a rat model of rheumatoid arthritis."7.96Telmisartan alone or in combination with etanercept improves anemia associated with rheumatoid arthritis in rats: a possible role of anti-inflammatory and reno-protective effects. ( Hasanin, AH; Mohamed, RH, 2020)
" Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months."6.64Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974)
"A double-blind cross-over study using a double placebo technique was employed to compare the effectiveness of daily alclofenac 3 g and phenylbutazone 300 mg in rheumatoid arthritis."5.04A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis. ( Chamberlain, MA; Wright, V, 1975)
" The present case control investigation was designed to evaluate the comparative toxicity of methotrexate and leflunomide on multiple organs in rheumatoid arthritis patients."4.31Comparative analysis of multiorgan toxicity induced by long term use of disease modifying anti-rheumatic drugs. ( Iqbal, MA; Mumtaz, T; Tahir, A; Tariq, MA, 2023)
"Telmisartan improved anemia and arthritis parameters and showed anti-inflammatory and reno-protective effects, in a rat model of rheumatoid arthritis."3.96Telmisartan alone or in combination with etanercept improves anemia associated with rheumatoid arthritis in rats: a possible role of anti-inflammatory and reno-protective effects. ( Hasanin, AH; Mohamed, RH, 2020)
"Development of arthritis and renal involvement was accompanied by significant raise in total leukocyte count, clinical score of inflammation, blood urea and serum creatinine as compared to healthy control rats (group A) till day 15 (p < 0."3.81Comparison of the Therapeutic Effects of Thymoquinone and Methotrexate on Renal Injury in Pristane Induced Arthritis in Rats. ( Faisal, R; Jehangir, T; Shinwari, L, 2015)
" The other woman had rheumatoid arthritis and developed acute tubular necrosis after treatment with gentamicin and cefoxitin."3.66Cefoxitin-associated renal failure. ( Bailey, RR; Reddy, J, 1981)
"Renal function was studied in 17 patients with rheumatoid arthritis who had each consumed between 5 and 20 kg of aspirin."3.65Aspirin and analgesic nephropathy. ( Craft, AW; Kerr, DN; Macklon, AF; Thompson, M, 1974)
" Almost half of the patients taking aspirin were unable to tolerate the drug in adequate dosage for six months."2.64Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin. ( Balme, HW; Berry, H; Hart, FD; Huskisson, EC; Scott, J; Wojtulewski, JA, 1974)
"In several cases with IgA nephropathy (IgAN), differential diagnosis is difficult due to the complication with other systemic diseases which can induce secondary IgAN."1.62Renal pathological analysis using galactose-deficient IgA1-specific monoclonal antibody is a strong tool for differentiation of primary IgA nephropathy from secondary IgA nephropathy. ( Fukao, Y; Kano, T; Kato, R; Lee, M; Makita, Y; Nakayama, M; Suzuki, H; Suzuki, Y, 2021)
" Modulation of PXR transactivation has revealed the selective and orally bioavailable CCR1 antagonist BMS-817399 (29), which entered clinical trials for the treatment of rheumatoid arthritis."1.40Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis. ( An, Y; Barrish, JC; Briceno, SW; Caceres-Cortes, J; Camac, DM; Caporuscio, C; Carter, PH; Cavallaro, C; Cvijic, ME; Davies, P; Dhar, M; Duncia, JV; Foster, WR; Gardner, DS; Grafstrom, RR; Hynes, J; Khan, JA; Liu, R; Patel, SR; Rose, AV; Santella, JB; Tebben, AJ; Vickery, RD; Watson, AJ; Wu, H; Yang, G; Yarde, M, 2014)
"Urea-treated binding protein also cross-reacts poorly in the RIA with CRF-BP."1.30Heterogeneity of the human corticotropin-releasing factor-binding protein. ( David, J; Kemp, CF; Lowry, PJ; Woods, RJ, 1997)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199029 (70.73)18.7374
1990's1 (2.44)18.2507
2000's1 (2.44)29.6817
2010's5 (12.20)24.3611
2020's5 (12.20)2.80

Authors

AuthorsStudies
Cellat, M1
İşler, CT1
Kutlu, T1
Kuzu, M1
Etyemez, M1
Alakuş, H1
Güvenç, M1
Mu, L1
Xu, H1
Hong, Y1
Zhou, W1
Wang, L1
Liu, P1
Chen, M1
Hu, Y1
Mumtaz, T1
Tahir, A1
Tariq, MA1
Iqbal, MA1
Hasanin, AH1
Mohamed, RH1
Lee, M1
Suzuki, H1
Kato, R1
Fukao, Y1
Nakayama, M1
Kano, T1
Makita, Y1
Suzuki, Y1
Santella, JB1
Gardner, DS1
Duncia, JV1
Wu, H1
Dhar, M1
Cavallaro, C1
Tebben, AJ1
Carter, PH1
Barrish, JC1
Yarde, M1
Briceno, SW1
Cvijic, ME1
Grafstrom, RR1
Liu, R1
Patel, SR1
Watson, AJ1
Yang, G1
Rose, AV1
Vickery, RD1
Caceres-Cortes, J1
Caporuscio, C1
Camac, DM1
Khan, JA1
An, Y1
Foster, WR1
Davies, P1
Hynes, J1
Chitra, P1
Bakthavatsalam, B1
Palvannan, T1
To, WS1
Aungier, SR1
Cartwright, AJ1
Ito, K1
Midwood, KS1
Faisal, R1
Shinwari, L1
Jehangir, T1
Spasovski, D1
Masin-Spasovska, J1
Nada, M1
Calovski, J1
Sandevska, E1
Osmani, B1
Sotirova, T1
Balkanov, S1
Dukovski, D1
Ljatifi, A1
Spasovski, G1
Podolin, PL1
Bolognese, BJ1
Foley, JJ1
Schmidt, DB1
Buckley, PT1
Widdowson, KL1
Jin, Q1
White, JR1
Lee, JM1
Goodman, RB1
Hagen, TR1
Kajikawa, O1
Marshall, LA1
Hay, DW1
Sarau, HM1
ARAPAKIS, G1
TRIBE, CR1
OYA, H1
HIRAZAWA, T1
HIRATA, F1
TANIUCHI, A1
ITO, N1
JICK, H1
KAMM, DE1
SNYDER, JG1
MORRISON, RS1
CHALMERS, TC1
BENDITT, EP2
ERIKSEN, N2
GERBER, DA1
Persselin, JE2
Louie, JS1
Stevens, RH2
Reddy, J1
Bailey, RR1
Woods, RJ1
Kemp, CF1
David, J1
Lowry, PJ1
Hingorani, K1
Chamberlain, MA1
Wright, V1
Simkin, PA1
Wilding, P1
Kendall, MJ2
Holder, R1
Grimes, JA1
Farr, M1
Hirose, SI2
Osler, AG1
Velican, C1
Kennedy, AC1
Burton, JA1
Allison, ME1
Josse, RG1
Huskisson, EC1
Wojtulewski, JA1
Berry, H1
Scott, J1
Hart, FD1
Balme, HW1
Burry, HC1
Macklon, AF1
Craft, AW1
Thompson, M1
Kerr, DN1
Normansell, DE1
Ferguson, J1
Boyle, JA1
Nuki, G1
Laursen, B1
Gormsen, J1
Thomas, JH1
Cockel, R1
Becker, JF1
Hawkins, CF1
Carr, DT1
McGuckin, WF1
Randall, RE1
Stacy, WK1
Toone, EC1
Prout, GR1
Madge, GE1
Shadomy, HJ1
Shadomy, S1
Utz, JP1
Dodson, WH1
Hollingsworth, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of a Cold Water Immersion (CWI) on Pain in People With Gouty Arthritis: A Community Based Randomized Controlled Trial[NCT04587544]76 participants (Actual)Interventional2019-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for urea and Arthritis, Rheumatoid

ArticleYear
A double blind trial to assess the value of alclofenac compared with phenylbutazone in the management of rheumatoid arthritis.
    Annals of the rheumatic diseases, 1975, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Eruptions; Female; Ga

1975
Treatment of rheumatoid arthritis with fenoprofen: comparison with aspirin.
    British medical journal, 1974, Feb-02, Volume: 1, Issue:5900

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Body Temperature; Clinical Trials as Topic; Deafness;

1974

Other Studies

39 other studies available for urea and Arthritis, Rheumatoid

ArticleYear
Investigation of the effects of safranal on the experimentally created rheumatoid arthritis model in rats.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:9

    Topics: Alanine; Animals; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; Aspartate Aminotrans

2022
Chemical compositions of Souliea vaginata (Maxim) Franch rhizome and their potential therapeutic effects on collagen-induced arthritis in rats.
    Journal of ethnopharmacology, 2023, Jun-28, Volume: 310

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Body Weight; Cytokines; Interleukin-10; Int

2023
Comparative analysis of multiorgan toxicity induced by long term use of disease modifying anti-rheumatic drugs.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Humans; Leflunomide; Methotrexate; Renal In

2023
Telmisartan alone or in combination with etanercept improves anemia associated with rheumatoid arthritis in rats: a possible role of anti-inflammatory and reno-protective effects.
    Pharmacological reports : PR, 2020, Volume: 72, Issue:2

    Topics: Anemia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Creatinine; Cytokines; Disease Mod

2020
Renal pathological analysis using galactose-deficient IgA1-specific monoclonal antibody is a strong tool for differentiation of primary IgA nephropathy from secondary IgA nephropathy.
    CEN case reports, 2021, Volume: 10, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Antiviral Agents; Arthritis, Rheumatoid; Crohn Disease; Diagnosis, Di

2021
Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis.
    Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18

    Topics: Animals; Arthritis, Rheumatoid; Biological Availability; Clinical Trials, Phase II as Topic; Drug Di

2014
Osteonecrosis with renal damage in HIV patients undergoing HAART.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:7

    Topics: Antiretroviral Therapy, Highly Active; Arthritis, Rheumatoid; Creatinine; Cystatin C; HIV Infections

2014
Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.
    British journal of pharmacology, 2015, Volume: 172, Issue:15

    Topics: Acetamides; Adalimumab; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dasatinib; Dose-Response Re

2015
Comparison of the Therapeutic Effects of Thymoquinone and Methotrexate on Renal Injury in Pristane Induced Arthritis in Rats.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:8

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzoquinones; Creati

2015
Diagnostic value of brush border enzymes of the proximal renal tubules in rheumatoid arthritis.
    Clinical laboratory, 2011, Volume: 57, Issue:5-6

    Topics: Adult; Aged; Arthritis, Rheumatoid; beta 2-Microglobulin; CD13 Antigens; Creatinine; Female; gamma-G

2011
A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-01, Volume: 169, Issue:11

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis,

2002
AMYLOIDOSIS IN RHEUMATOID ARTHRITIS INVESTIGATED BY MEANS OF RECTAL BIOPSY.
    Annals of the rheumatic diseases, 1963, Volume: 22

    Topics: Amyloidosis; Arthritis; Arthritis, Rheumatoid; Biopsy; Blood Chemical Analysis; Geriatrics; Humans;

1963
[CLINICAL CONTRIBUTION TO THE USE OF THE NEW ANALGESIC AND ANTIPYRETIC CALCIUM-ACETYL-SALICYLATE CARBAMIDE].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Analgesics; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Fibromyalgia; Humans; Neuritis;

1963
ON THE CONCENTRATING DEFECT IN CIRRHOSIS OF THE LIVER.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Alcoholism; Arthritis; Arthritis, Rheumatoid; Coronary Disease; Dehydration; Dermatitis; Diabetes Me

1964
AMYLOID. II. STARCH GEL ELECTROPHORETIC ANALYSIS OF SOME PROTEINS EXTRACTED FROM AMYLOID.
    Archives of pathology, 1964, Volume: 78

    Topics: Adolescent; Amyloid; Amyloidosis; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Bronchiecta

1964
ROLE OF THE SULFHYDRYL GROUP IN THE DENATURATION OF HUMAN GAMMA-GLOBULIN.
    Journal of immunology (Baltimore, Md. : 1950), 1964, Volume: 92

    Topics: Acetates; Arthritis; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; gamma-Globulins; Hot Temp

1964
Clonally restricted anti-IgG antibodies in rheumatoid arthritis.
    Arthritis and rheumatism, 1984, Volume: 27, Issue:12

    Topics: Antibodies, Anti-Idiotypic; Antibody Specificity; Arthritis, Rheumatoid; Blood Proteins; Chemical Fr

1984
Cefoxitin-associated renal failure.
    The New Zealand medical journal, 1981, May-27, Volume: 93, Issue:684

    Topics: Acute Kidney Injury; Aged; Aminoglycosides; Arthritis, Rheumatoid; Cefoxitin; Creatinine; Escherichi

1981
Heterogeneity of the human corticotropin-releasing factor-binding protein.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:5

    Topics: Animals; Arthritis, Rheumatoid; Carrier Proteins; CHO Cells; Cricetinae; Electrophoresis, Polyacryla

1997
Benorylate: a report on 2 years' experience of its use in rheumatoid arthritis and other chronic rheumatic diseases.
    Scandinavian journal of rheumatology. Supplement, 1975, Volume: 13

    Topics: Arthritis, Rheumatoid; Blood Sedimentation; Drug Evaluation; Dyspepsia; Humans; Nausea; Osteoarthrit

1975
Synovial permeability in rheumatoid arthritis.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:7

    Topics: Arthritis, Rheumatoid; Benzyl Alcohols; Glucose; Humans; Knee Joint; Microcirculation; Models, Biolo

1979
The influence of drugs and disease activity on biochemical and haematological data in rheumatoid arthritis.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Oct-15, Volume: 64, Issue:2

    Topics: Arthritis, Rheumatoid; Aspirin; Bilirubin; Calcium; Cholesterol; Creatinine; Female; Hemoglobins; Hu

1975
Anti-Fab antibodies in humans. Predominance of minor immunoglobulin G subclasses in rheumatoid arthritis.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:2

    Topics: Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Dialysis; Enzyme-Linked Immunosorbent Assay; Huma

1985
Interaction of rheumatoid factors with urea-denatured human gamma-globulin and its subunits.
    Journal of immunology (Baltimore, Md. : 1950), 1967, Volume: 98, Issue:3

    Topics: Arthritis, Rheumatoid; gamma-Globulins; Hemagglutination Tests; Humans; Immunodiffusion; Rheumatoid

1967
The biologic activities of denatured human IgG and its heavy chains.
    Journal of immunology (Baltimore, Md. : 1950), 1970, Volume: 104, Issue:3

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Arthritis, Rheumatoid; Capillary Permeability; Comple

1970
Histochemical evidence for the role of macromolecular structural stability in the pathogenesis of diseases.
    Acta histochemica, 1970, Volume: 37, Issue:2

    Topics: Adult; Aged; Aorta; Arteriosclerosis; Arthritis, Rheumatoid; Collagen; Connective Tissue; Ear Ossicl

1970
Tuberculosis as a continuing cause of renal amyloidosis.
    British medical journal, 1974, Sep-28, Volume: 3, Issue:5934

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Autopsy; Biopsy; C

1974
Gram-positive septicaemia in rheumatoid arthritis.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:3

    Topics: Ampicillin; Arthritis, Rheumatoid; Fusidic Acid; Humans; Lincomycin; Male; Middle Aged; Penicillin R

1974
Bacteriuria in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1973, Volume: 32, Issue:3

    Topics: Arthritis, Rheumatoid; Bacteriuria; Creatinine; Female; Glomerular Filtration Rate; Humans; Male; Mi

1973
Aspirin and analgesic nephropathy.
    British medical journal, 1974, Mar-30, Volume: 1, Issue:5908

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Creatinine; Female; Humans; Kidney Dise

1974
Chemical similarity among amyloid substances associated with long standing inflammation.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 26, Issue:6

    Topics: Acrylamides; Adult; Aged; Amino Acid Sequence; Amyloid; Amyloidosis; Arthritis, Juvenile; Arthritis,

1972
Anti- -globulins in rheumatoid arthritis sera. II. The reactivity of anti- -globulin rheumatoid factors with altered G-globulin.
    Immunochemistry, 1971, Volume: 8, Issue:7

    Topics: Animals; Antibodies, Anti-Idiotypic; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Erythrocytes

1971
Rheological evidence for the existence of dissociated macromolecular complexes in rheumatoid synovial fluid.
    Clinical science, 1969, Volume: 37, Issue:3

    Topics: Arthritis, Rheumatoid; Elasticity; Guanidines; Humans; Knee Joint; Macromolecular Substances; Osteoa

1969
Pharmacological enhancement and short-term stimulation of blood fibrinolytic activity.
    Scandinavian journal of haematology, 1969, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aged; Aminocaproates; Anticholesteremic Agents; Arteriosclerosis; Arthritis, Rheu

1969
Values of serum iron in patients over sixty.
    Gerontologia clinica, 1971, Volume: 13, Issue:1

    Topics: Aged; Anemia, Hypochromic; Anemia, Pernicious; Arthritis, Rheumatoid; Circadian Rhythm; Dementia; Fe

1971
Serum biochemical values in rheumatoid disease.
    Annals of the rheumatic diseases, 1971, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferases; B

1971
Pleural fluid glucose. Serial observation of its concentration following oral administration of glucose to patients with rheumatoid pleural effusions and malignant effusions.
    The American review of respiratory disease, 1968, Volume: 97, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Blood Glucose; Blood Urea Nitrogen; Female; Glucose; Humans; Male; Mid

1968
Cryptococcal pyelonephritis.
    The New England journal of medicine, 1968, Jul-11, Volume: 279, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amphotericin B; Arthritis, Rheumatoid; Aspirin; Cryptococcosis

1968
Pleural effusion in rheumatoid arthritis. Impaired transport of glucose.
    The New England journal of medicine, 1966, Dec-15, Volume: 275, Issue:24

    Topics: Aged; Arthritis, Rheumatoid; Biopsy; Cholesterol; Glucose; Humans; In Vitro Techniques; Male; Middle

1966