Page last updated: 2024-10-21

urea and Antidiuretic Hormone, Inappropriate Secretion

urea has been researched along with Antidiuretic Hormone, Inappropriate Secretion in 64 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
" Following failed attempts to correct hyponatremia with fluid restriction and other therapeutics, urea normalized sodium levels and allowed liberalization of formula volumes, which resulted in improved weight gain."8.31Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1. ( Cui, J; Halpin, K; Paprocki, E, 2023)
"We retrospectively analysed 36 cancer patients affected by moderate or profound SIAD-induced chronic hyponatremia, who started oral urea (initial daily dose 15 g or 30 g) without fluid restriction between July 2013 and July 2018."7.91Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence. ( Arvat, E; Castellana, E; Cattel, F; D'Angelo, V; Grossi, E; Nervo, A; Rosso, D, 2019)
"In our Department, enteral urea is routinely administered to patients with acute brain injury who develop hyponatremia consistent with SIADH and do not respond to an initial sodium load."7.85Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia. ( Annoni, F; Brimioulle, S; Creteur, J; Fontana, V; Taccone, FS; Vincent, JL, 2017)
"We report the successful use of oral urea in the management of children with chronic syndrome of inappropriate antidiuretic hormone secretion (SIAD)."7.73Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children. ( Feldman, BJ; Geller, DH; Gitelman, SE; Huang, EA; Rosenthal, SM; Schwartz, ID, 2006)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."7.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"Reported successes in the treatment of hyponatremia due to SIADH by administration of urea and normal saline led to the authors' routine use of this therapy for hyponatremic neurosurgical patients."5.28Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients. ( Harbaugh, RE; Reeder, RF, 1989)
" Urea and vaptans can be effective treatments for the syndrome of inappropriate antidiuresis and hyponatremia in patients with heart failure, but have adverse effects (eg, poor palatability and gastric intolerance with urea; and overly rapid correction of hyponatremia and increased thirst with vaptans)."5.22Diagnosis and Management of Hyponatremia: A Review. ( Adrogué, HJ; Madias, NE; Tucker, BM, 2022)
"Urea has been recently proposed for the management of hyponatremia linked to the syndrome of inappropriate secretion of ADH (SIADH)."4.90Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review. ( de Solà-Morales, O; Riera, M, 2014)
" Following failed attempts to correct hyponatremia with fluid restriction and other therapeutics, urea normalized sodium levels and allowed liberalization of formula volumes, which resulted in improved weight gain."4.31Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1. ( Cui, J; Halpin, K; Paprocki, E, 2023)
"We retrospectively analysed 36 cancer patients affected by moderate or profound SIAD-induced chronic hyponatremia, who started oral urea (initial daily dose 15 g or 30 g) without fluid restriction between July 2013 and July 2018."3.91Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence. ( Arvat, E; Castellana, E; Cattel, F; D'Angelo, V; Grossi, E; Nervo, A; Rosso, D, 2019)
"In our Department, enteral urea is routinely administered to patients with acute brain injury who develop hyponatremia consistent with SIADH and do not respond to an initial sodium load."3.85Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia. ( Annoni, F; Brimioulle, S; Creteur, J; Fontana, V; Taccone, FS; Vincent, JL, 2017)
"Urea administration appears useful for the treatment of SIADH-associated hyponatremia in critically ill patients."3.78Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with urea in critically ill patients. ( Bankir, L; Biston, P; Coussement, J; Danguy, C; Defrance, P; Piagnerelli, M; Zouaoui-Boudjeltia, K, 2012)
"We report the successful use of oral urea in the management of children with chronic syndrome of inappropriate antidiuretic hormone secretion (SIAD)."3.73Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children. ( Feldman, BJ; Geller, DH; Gitelman, SE; Huang, EA; Rosenthal, SM; Schwartz, ID, 2006)
"The high fractional excretion (FE) of uric acid observed in hyponatremia associated with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is commonly attributed to the volume-expanded state, although volume expansion in normonatremic volunteers is unable to increase urate clearance to a degree similar to that in SIADH."3.70Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion. ( Decaux, G; Musch, W; Prospert, F; Soupart, A, 2000)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."3.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"Urea has efficacy similar to that of vaptans for treatment of chronic SIADH."2.77Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH. ( Coffernils, M; Couturier, B; Decaux, G; Gankam-Kengne, F; Soupart, A, 2012)
" In short and long term studies, tolvaptane has been shown to be effective in raising serum sodium levels in a predictable fashion in patients with SIADH with only few side effects, when serum sodium was frequently monitored and dosage of tolvaptans was properly adjusted."2.47[Treatment of hyponatremia: new developments and controversies]. ( Hensen, J, 2011)
"SIADH is a common cause of hyponatremia in hospitalized patients."2.37Management of the syndrome of inappropriate secretion of antidiuretic hormone. ( Kinzie, BJ, 1987)
"Urea has shown to be a safe and cost-effective option for the treatment of hyponatremia caused by SIADH."1.72Clinical efficacy of urea treatment in syndrome of inappropriate antidiuretic hormone secretion. ( Domínguez-Escribano, JR; López-Penabad, L; Mirete-López, RM; Perelló-Camacho, E; Pinedo-Esteban, MR; Pomares-Gómez, FJ, 2022)
"In hospitalised patients with a serum sodium level ≤ 129 mmol/l due to SIADH, urea in a dosage of 0."1.56Urea for hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion. ( de Boer, MP; Hempenius, L; van Roon, EN; Woudstra, J, 2020)
"This hyponatremia is saline-responsive, but relapse can be frequently observed."1.51Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
. ( Decaux, G; Musch, W, 2019)
"Hyponatremia is the main complication of inappropriate antidiuretic hormone secretion (SIADH), sometimes fatal."1.38Inappropriate antidiuretic hormone secretion: long-term successful urea treatment. ( Cachat, F; Chehade, H; Girardin, E; Rosato, L, 2012)
"Hyponatremia was induced in male Sprague-Dawley rats by water loading and subcutaneous infusion of 1-deamino-8-D-arginine vasopressin (dDAVP)."1.33BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats. ( Arata, T; Ejima, Y; Hatano, R; Kazama, I; Matsubara, M; Michimata, M; Miyama, N; Sasaki, S; Sato, A; Satomi, S; Suzuki, K; Suzuki, M, 2005)
"Aldosterone levels were much lower in ACTH deficiency patients during the hyponatremic state (33 +/- 40 pg/ml) when compared with the nonendocrine SIADH (120 +/- 60 pg/ml; P < 0."1.32Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency. ( Decaux, G; Musch, W; Penninckx, R; Soupart, A, 2003)
"Reported successes in the treatment of hyponatremia due to SIADH by administration of urea and normal saline led to the authors' routine use of this therapy for hyponatremic neurosurgical patients."1.28Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients. ( Harbaugh, RE; Reeder, RF, 1989)
"Urea treatment also induced a persistent osmotic diuresis, allowing a normal daily intake of water despite SIADH."1.26Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by urea. ( Brimioulle, S; Decaux, G; Genette, F; Mockel, J, 1980)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199012 (18.75)18.7374
1990's5 (7.81)18.2507
2000's16 (25.00)29.6817
2010's23 (35.94)24.3611
2020's8 (12.50)2.80

Authors

AuthorsStudies
Perelló-Camacho, E1
Pomares-Gómez, FJ1
López-Penabad, L1
Mirete-López, RM1
Pinedo-Esteban, MR1
Domínguez-Escribano, JR1
Adrogué, HJ1
Tucker, BM1
Madias, NE2
Cui, J3
Halpin, K3
Paprocki, E3
Bioletto, F1
Varaldo, E1
Prencipe, N1
Benso, A1
Berton, AM1
Veligratli, F1
Alexandrou, D1
Shah, S1
Amin, R1
Dattani, M1
Gan, HW1
Famuboni, A1
Lopez-Garcia, C1
Trompeter, R1
Bockenhauer, D2
Monnerat, S1
Atila, C1
Baur, F1
Santos de Jesus, J1
Refardt, J1
Dickenmann, M1
Christ-Crain, M2
Wendt, R1
Fenves, AZ1
Geisler, BP1
Woudstra, J1
de Boer, MP1
Hempenius, L1
van Roon, EN1
Cailleaux, A1
Mahieu, F1
Heinrichs, C2
Adams, B1
Ismaili, K1
Brachet, C2
Baldrighi, M1
Castello, LM1
Bartoli, E1
Bardanzellu, F1
Pintus, MC1
Masile, V1
Fanos, V2
Marcialis, MA2
Musch, W8
Decaux, G24
Moritz, ML1
Nervo, A1
D'Angelo, V1
Rosso, D1
Castellana, E1
Cattel, F1
Arvat, E1
Grossi, E1
de Solà-Morales, O1
Riera, M1
Gómez Valbuena, I1
Alonso Pérez, L1
Alioto, D1
Cañamares Orbis, I1
Ferrari Piquero, JM1
Santiago Pérez, A1
Runkle de la Vega, I1
Peña Pedrosa, JA1
Arias Fernández, ML1
Cuesta, M1
Hannon, MJ1
Thompson, CJ1
Annoni, F1
Fontana, V1
Brimioulle, S3
Creteur, J1
Vincent, JL1
Taccone, FS1
Nigro, N1
Winzeler, B1
Suter-Widmer, I1
Schuetz, P1
Arici, B1
Bally, M1
Blum, CA1
Nickel, CH1
Bingisser, R1
Bock, A1
Huber, A1
Müller, B1
Dufek, S1
Booth, C1
Carroll, A1
Van't Hoff, W1
Kleta, R1
Dessì, A1
Contu, S1
Varsavsky, M1
Quesada Charneco, M1
Rozas Moreno, P1
Lichtwarck-Aschoff, M1
Pippi, A1
Dietrich, B1
Hensen, J1
Chehade, H1
Rosato, L1
Girardin, E1
Cachat, F1
Coussement, J1
Danguy, C1
Zouaoui-Boudjeltia, K1
Defrance, P1
Bankir, L1
Biston, P1
Piagnerelli, M1
Soupart, A8
Coffernils, M2
Couturier, B1
Gankam-Kengne, F1
Trolle, C1
Rittig, S1
Frøkjær, J1
Jørgensen, JO1
Bichet, DG1
Vandergheynst, F1
Penninckx, R2
Hedeshi, A1
Kazama, I1
Hatano, R1
Michimata, M1
Suzuki, K1
Arata, T1
Suzuki, M1
Miyama, N1
Sato, A1
Satomi, S1
Ejima, Y1
Sasaki, S1
Matsubara, M1
Huang, EA1
Feldman, BJ1
Schwartz, ID1
Geller, DH1
Rosenthal, SM1
Gitelman, SE1
Liamis, G1
Christidis, D1
Alexandridis, G1
Bairaktari, E1
Elisaf, M1
Verfaillie, L1
Leblanc, PE1
Cheisson, G1
Geeraerts, T1
Tazarourte, K1
Duranteau, J1
Vigué, B1
Renneboog, B1
Fenske, W1
Störk, S1
Koschker, AC1
Blechschmidt, A1
Lorenz, D1
Wortmann, S1
Allolio, B1
Genette, F3
Mockel, J3
Wallerstedt, S1
Unger, J1
Schlesser, M2
Prospert, F6
Namias, B4
Callejas, JL1
Vallejo, I1
Palmero, C1
Fernández-Moyano, A1
Perks, WH1
Walters, EH1
Tams, IP1
Prowse, K1
Martinez-Maldonado, M1
Opava-Stitzer, S1
Cauchie, P1
Reeder, RF1
Harbaugh, RE1
Kinzie, BJ1
Verbalis, JG1
Baldwin, EF1
Neish, PN1
Robinson, AG1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Hydration After Surgery Using Boluses of Balanced Salt Solution[NCT05285371]Early Phase 170 participants (Anticipated)Interventional2022-02-22Active, not recruiting
Urea for Chronic Hyponatremia: A Pilot Study[NCT04588207]Phase 22 participants (Actual)Interventional2021-12-28Terminated (stopped due to Unable to recruit participants)
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status at the Access in the Emergency Department and at the Subsequent Re-evaluation in Hospital Wards[NCT04402190]123 participants (Actual)Observational2018-06-01Completed
Research Project: Pilot Study on Oral Urea Use in Patients at High Risk of Kidney Stone Recurrence[NCT04727606]Phase 20 participants (Actual)Interventional2023-01-15Withdrawn (stopped due to We never got Health Canada approval)
[NCT00541944]120 participants (Anticipated)Observational2007-04-30Recruiting
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987]122 participants (Actual)Observational2019-07-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for urea and Antidiuretic Hormone, Inappropriate Secretion

ArticleYear
Diagnosis and Management of Hyponatremia: A Review.
    JAMA, 2022, 07-19, Volume: 328, Issue:3

    Topics: Coma; Heart Failure; Humans; Hyponatremia; Hypovolemia; Inappropriate ADH Syndrome; Prospective Stud

2022
Long-term efficacy of empagliflozin as an add-on treatment for chronic SIAD: a case report and literature review.
    Hormones (Athens, Greece), 2023, Volume: 22, Issue:2

    Topics: Aged; Diabetes Mellitus, Type 2; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Sodium; Ure

2023
Tolvaptan and urea in paediatric hyponatraemia.
    Pediatric nephrology (Berlin, Germany), 2024, Volume: 39, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Child; Humans; Hyponatremia; Inappropriate

2024
Use of Urea for the Syndrome of Inappropriate Secretion of Antidiuretic Hormone: A Systematic Review.
    JAMA network open, 2023, 10-02, Volume: 6, Issue:10

    Topics: Adult; Demyelinating Diseases; Humans; Inappropriate ADH Syndrome; Sodium; Urea; Vasopressins

2023
Focus on neonatal and infantile onset of nephrogenic syndrome of inappropriate antidiuresis: 12 years later.
    Pediatric nephrology (Berlin, Germany), 2019, Volume: 34, Issue:5

    Topics: Age of Onset; Antidiuretic Hormone Receptor Antagonists; Clinical Trials as Topic; Diuretics, Osmoti

2019
Syndrome of Inappropriate Antidiuresis.
    Pediatric clinics of North America, 2019, Volume: 66, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Child; Diagnosis, Differential; Hospitalization; Humans;

2019
Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2014, Volume: 61, Issue:9

    Topics: Disease Management; Drug Evaluation; Evidence-Based Medicine; Humans; Hypernatremia; Hypokalemia; Hy

2014
Diagnosis and treatment of hyponatraemia in neurosurgical patients.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2016, Volume: 63, Issue:5

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Antidiuretic Hormone Receptor Antagonists; Brain

2016
Nephrogenic syndrome of inappropriate antidiuresis: a novel cause of euvolemic hypotonic hyponatremia in newborns. Diagnosis and practical management.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22 Suppl 3

    Topics: Administration, Oral; Diabetes Insipidus, Nephrogenic; Female; Fluid Therapy; Humans; Hyponatremia;

2009
[Treatment of hyponatremia: new developments and controversies].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:17

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Volume; Drinking; Humans; Hyponatremi

2011
Long-term treatment of hyponatremic patients with nephrogenic syndrome of inappropriate antidiuresis: personal experience and review of published case reports.
    Nephron. Clinical practice, 2012, Volume: 120, Issue:3

    Topics: Adult; Aged; Diuretics; Furosemide; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappropriate

2012
[Does cerebral salt wasting syndrome exist?].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11

    Topics: Adrenal Cortex Hormones; Blood Pressure; Brain Diseases; Diagnosis, Differential; Humans; Hyponatrem

2007
Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:4

    Topics: Acid-Base Equilibrium; Bicarbonates; Biomarkers; Clinical Laboratory Techniques; Creatinine; Diagnos

2008
Management of the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical pharmacy, 1987, Volume: 6, Issue:8

    Topics: Demeclocycline; Drug-Related Side Effects and Adverse Reactions; Humans; Hyponatremia; Inappropriate

1987

Trials

3 trials available for urea and Antidiuretic Hormone, Inappropriate Secretion

ArticleYear
Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study-the TREASURE study.
    European journal of endocrinology, 2023, Aug-02, Volume: 189, Issue:2

    Topics: Creatinine; Dietary Supplements; Humans; Hyponatremia; Inappropriate ADH Syndrome; Powders; Sodium;

2023
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985.
    The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Diuresis; Humans; Hyponatremia; Ina

2001

Other Studies

47 other studies available for urea and Antidiuretic Hormone, Inappropriate Secretion

ArticleYear
Clinical efficacy of urea treatment in syndrome of inappropriate antidiuretic hormone secretion.
    Scientific reports, 2022, 06-17, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Humans; Ina

2022
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea for hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion.
    The Netherlands journal of medicine, 2020, Volume: 78, Issue:3

    Topics: Aged; Aged, 80 and over; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged

2020
[Nephrogenic syndrome of inappropriate antidiuresis: Early diagnosis avoids severe hyponatremia complications].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:7

    Topics: Early Diagnosis; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappropriate ADH Syndrome; Infan

2017
Comment on "Mild water restriction with or without urea for the longterm treatment of SIADH: Can urine osmolality help the choice?" by Decaux et al.
    European journal of internal medicine, 2018, Volume: 52

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Urea; Water

2018
High fractional potassium excretion in symptomatic hyponatremia.
    European journal of internal medicine, 2019, Volume: 59

    Topics: Aged; Diuretics; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Aged; Polydipsia; Potassiu

2019
Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence.
    Clinical endocrinology, 2019, Volume: 90, Issue:6

    Topics: Aged; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Neoplasms; Retros

2019
Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
.
    Clinical nephrology, 2019, Volume: 91, Issue:6

    Topics: Aged; Aged, 80 and over; Calcium; Diuresis; Diuretics; Female; Fluid Therapy; Humans; Hyponatremia;

2019
[Treatment with urea as an alternative to tolvaptan for the syndrome of inappropriate secretion of antidiuretic hormone].
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2014, Jul-01, Volume: 38, Issue:4

    Topics: Aged, 80 and over; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Female; Humans; Inapprop

2014
[Response to clinical case report: treatment with urea as an alternative to tolvaptan for the syndrome of inappropriate secretion of antidiuretic hormone].
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2014, Nov-03, Volume: 38, Issue:6

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea; Vasopressins

2014
Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia.
    Journal of neurosurgical anesthesiology, 2017, Volume: 29, Issue:4

    Topics: Acute Disease; Adult; Aged; APACHE; Brain Injuries; Female; Humans; Hyponatremia; Inappropriate ADH

2017
Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: 'The Co-MED Study'.
    Clinical endocrinology, 2017, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Glycopeptides; Hospitalization; Humans; Hydrocorti

2017
Urea is successful in treating inappropriate antidiuretic hormone secretion in an infant.
    Acta paediatrica (Oslo, Norway : 1992), 2017, Volume: 106, Issue:3

    Topics: Antidiuretic Hormone Receptor Antagonists; Humans; Inappropriate ADH Syndrome; Infant; Male; Tolvapt

2017
[Urea as therapeutic option for the treatment of the syndrome of inappropriate antidiuretic hormone secretion].
    Medicina clinica, 2011, Jul-23, Volume: 137, Issue:5

    Topics: Amitriptyline; Carbamazepine; Comorbidity; Demeclocycline; Diabetic Neuropathies; Diuretics; Furosem

2011
[Supplement to continuing medical education article "Dysnatremia in intensive care patients"].
    Der Anaesthesist, 2011, Volume: 60, Issue:4

    Topics: Critical Care; Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Urea; Vasopr

2011
Inappropriate antidiuretic hormone secretion: long-term successful urea treatment.
    Acta paediatrica (Oslo, Norway : 1992), 2012, Volume: 101, Issue:1

    Topics: Child, Preschool; Chronic Disease; Diuretics, Osmotic; Female; Humans; Hyponatremia; Inappropriate A

2012
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with urea in critically ill patients.
    American journal of nephrology, 2012, Volume: 35, Issue:3

    Topics: Adult; Aged; Critical Illness; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middl

2012
[Diagnostics and new treatment methods of syndrome of inappropriate antidiuretic hormone secretion (SIADH)].
    Ugeskrift for laeger, 2012, Apr-09, Volume: 174, Issue:15

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Diagnosis, Differential; Humans; Inappropri

2012
What is the role of vaptans in routine clinical nephrology?
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Female; Humans; Inappropriate ADH Syndrome;

2012
Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Aldosterone; Bicarbonates; Carbon Dioxide; Dia

2003
Low sodium excretion in SIADH patients with low diuresis.
    Nephron. Physiology, 2004, Volume: 96, Issue:1

    Topics: Aged; Alcohol Withdrawal Seizures; Alcoholism; Creatinine; Diagnosis, Differential; Diuresis; Duoden

2004
BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Aquaporins; Benzazepines; Deamino A

2005
Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children.
    The Journal of pediatrics, 2006, Volume: 148, Issue:1

    Topics: Administration, Oral; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Hyponatremi

2006
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2007, Volume: 55, Issue:1

    Topics: Aged; Creatinine; Diagnosis, Differential; Diuretics; Edema; Female; Humans; Hyponatremia; Hypovolem

2007
Age-related increase in plasma urea level and decrease in fractional urea excretion: clinical application in the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical journal of the American Society of Nephrology : CJASN, 2006, Volume: 1, Issue:5

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Creatinine; Female; Humans; Inappropriate A

2006
Idiopathic hyponatremia in a young patient: look at the sinus.
    The American journal of medicine, 2008, Volume: 121, Issue:5

    Topics: Adult; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Neuroblastoma; Radiography; Urea

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
The syndrome of inappropriate secretion of ADH (SIADH): recent clinical data.
    Acta clinica Belgica, 1984, Volume: 39, Issue:1

    Topics: Demeclocycline; Diuretics; Humans; Inappropriate ADH Syndrome; Kidney; Urea

1984
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by long loop diuretics.
    Nephron, 1983, Volume: 35, Issue:2

    Topics: Adolescent; Aged; Diuresis; Ethacrynic Acid; Female; Furosemide; Humans; Inappropriate ADH Syndrome;

1983
Urea for long-term treatment of syndrome of inappropriate secretion of antidiuretic hormone.
    British medical journal (Clinical research ed.), 1981, Oct-24, Volume: 283, Issue:6299

    Topics: Drug Evaluation; Humans; Inappropriate ADH Syndrome; Osmolar Concentration; Sodium; Urea

1981
Hypouremia in the syndrome of inappropriate secretion of antidiuretic hormone.
    Annals of internal medicine, 1980, Volume: 93, Issue:5

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea; Vasopressins

1980
[Hyponatremia in clinical practice].
    Lakartidningen, 1981, Nov-18, Volume: 78, Issue:47

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea

1981
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by urea.
    The American journal of medicine, 1980, Volume: 69, Issue:1

    Topics: Adult; Aged; Body Weight; Diuresis; Drinking; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidn

1980
Urea therapy for inappropriate antidiuretic hormone secretion from tuberculous meningitis.
    JAMA, 1980, Aug-08, Volume: 244, Issue:6

    Topics: Brain Edema; Diuresis; Humans; Hypertension; Hyponatremia; Inappropriate ADH Syndrome; Intracranial

1980
Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia.
    Clinical nephrology, 1994, Volume: 42, Issue:2

    Topics: Acid-Base Equilibrium; Diuretics; Heart Failure; Humans; Hyponatremia; Hypopituitarism; Inappropriat

1994
5-year treatment of the chronic syndrome of inappropriate secretion of ADH with oral urea.
    Nephron, 1993, Volume: 63, Issue:4

    Topics: Administration, Oral; Aged; Chronic Disease; Drinking; Female; Humans; Inappropriate ADH Syndrome; U

1993
Effect of urea and indomethacin intake on solute excretion in the syndrome of inappropriate secretion of antidiuretic hormone.
    Nephron, 1993, Volume: 64, Issue:1

    Topics: Aged; Chlorides; Humans; Hyponatremia; Inappropriate ADH Syndrome; Indomethacin; Middle Aged; Natriu

1993
Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Glomerular Filtration Rate; Humans; Hyponatremia

2000
Long-term treatment of patients with inappropriate secretion of antidiuretic hormone by the vasopressin receptor antagonist conivaptan, urea, or furosemide.
    The American journal of medicine, 2001, Volume: 110, Issue:7

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Diuretics; Female; Furosemide; Humans; Inap

2001
Utility and limitations of biochemical parameters in the evaluation of hyponatremia in the elderly.
    International urology and nephrology, 2001, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Isot

2001
[Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with urea].
    Medicina clinica, 2002, Apr-27, Volume: 118, Issue:15

    Topics: Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Urea

2002
Demeclocycline in the treatment of the syndrome of inappropriate secretion of antidiuretic hormone.
    Thorax, 1979, Volume: 34, Issue:3

    Topics: Adult; Aged; Creatinine; Demeclocycline; Female; Humans; Inappropriate ADH Syndrome; Male; Middle Ag

1979
Free water clearance curves during saline, mannitol, glucose and urea diuresis in the rat.
    The Journal of physiology, 1978, Volume: 280

    Topics: Animals; Diuresis; Female; Glucose; Inappropriate ADH Syndrome; Male; Mannitol; Rats; Sodium Chlorid

1978
Raised urea clearance in cirrhotic patients with high uric acid clearance is related to low salt excretion.
    Gut, 1992, Volume: 33, Issue:8

    Topics: Adult; Aged; Ascites; Blood Volume; Humans; Inappropriate ADH Syndrome; Liver Cirrhosis; Middle Aged

1992
Dissociation between uric acid and urea clearances in the syndrome of inappropriate secretion of antidiuretic hormone related to salt excretion.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:5

    Topics: Adult; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Aged; Osmolar Concentration; Prospec

1990
Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients.
    Journal of neurosurgery, 1989, Volume: 70, Issue:2

    Topics: Blood Urea Nitrogen; Humans; Hyponatremia; Inappropriate ADH Syndrome; Injections, Intravenous; Nerv

1989
Effect of protein intake and urea on sodium excretion during inappropriate antidiuresis in rats.
    Metabolism: clinical and experimental, 1988, Volume: 37, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Deamino Arginine Vasopressin; Dietary Proteins; Inappropriate ADH Synd

1988