urea has been researched along with Amyotrophic Lateral Sclerosis in 8 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although oral creatine supplementation is very popular among athletes, no prospective placebo-controlled studies on the adverse effects of long-term supplementation have yet been conducted." | 2.71 | Few adverse effects of long-term creatine supplementation in a placebo-controlled trial. ( Beijer, C; Groeneveld, GJ; Kalmijn, S; van den Berg, LH; Veldink, JH; Wokke, JH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Del Poggetto, E | 2 |
| Chiti, F | 2 |
| Bemporad, F | 1 |
| Gori, L | 1 |
| Ahn, SW | 1 |
| Kim, JE | 1 |
| Park, KS | 1 |
| Choi, WJ | 1 |
| Hong, YH | 1 |
| Kim, SM | 1 |
| Kim, SH | 2 |
| Lee, KW | 1 |
| Sung, JJ | 1 |
| Cassina, P | 1 |
| Pehar, M | 1 |
| Vargas, MR | 1 |
| Castellanos, R | 1 |
| Barbeito, AG | 1 |
| Estévez, AG | 1 |
| Thompson, JA | 1 |
| Beckman, JS | 1 |
| Barbeito, L | 1 |
| Groeneveld, GJ | 1 |
| Beijer, C | 1 |
| Veldink, JH | 1 |
| Kalmijn, S | 1 |
| Wokke, JH | 1 |
| van den Berg, LH | 1 |
| Koh, SH | 1 |
| Kim, Y | 1 |
| Kim, HY | 1 |
| Hwang, S | 1 |
| Lee, CH | 1 |
| Welch, KM | 1 |
| Goldberg, DM | 1 |
| Wochner, RD | 1 |
| Weissman, SM | 1 |
| Waldmann, TA | 1 |
| Houston, D | 1 |
| Berlin, NI | 1 |
1 trial available for urea and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Few adverse effects of long-term creatine supplementation in a placebo-controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Albuminuria; Amyotrophic Lateral Sclerosis; Creatine; | 2005 |
7 other studies available for urea and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Anilino Naphthalenesulfonates; Circular Dichroism; Escherichia coli; | 2015 |
Biophysical analysis of three novel profilin-1 variants associated with amyotrophic lateral sclerosis indicates a correlation between their aggregation propensity and the structural features of their globular state.
Topics: Amyotrophic Lateral Sclerosis; Humans; Mutation; Profilins; Protein Aggregates; Protein Conformation | 2016 |
The neuroprotective effect of the GSK-3β inhibitor and influence on the extrinsic apoptosis in the ALS transgenic mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Caspase 8; Cell Count; Disease Models, Animal; fa | 2012 |
Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspas | 2005 |
Inhibition of glycogen synthase kinase-3 suppresses the onset of symptoms and disease progression of G93A-SOD1 mouse model of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Caspase 3; Cell Death; Cyclooxygenase 2; | 2007 |
Response of serum enzymes and other biochemical constituents to strenuous exercise in control subjects and patients with motor neurone disease.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Aspartate Aminotransferases; Bicarbonates; Creatine Kina | 1973 |
Direct measurement of the rates of synthesis of plasma proteins in control subjects and patients with gastrointestinal protein loss.
Topics: Amyotrophic Lateral Sclerosis; Arginine; Bicarbonates; Blood Proteins; Carbon Isotopes; Crohn Diseas | 1968 |