Page last updated: 2024-10-21

urea and Airflow Obstruction, Chronic

urea has been researched along with Airflow Obstruction, Chronic in 14 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
" The purpose of this study was to determine the intrapulmonary profile of high-dose (750 mg) levofloxacin in patients during an acute exacerbation of chronic bronchitis (AECB)."9.16Bronchopulmonary pharmacokinetic and pharmacodynamic profiles of levofloxacin 750 mg once daily in adults undergoing treatment for acute exacerbation of chronic bronchitis. ( Baughman, RP; Nicolau, DP; Sutherland, C; Winget, D, 2012)
" We examined the effect of 1 week treatment with BAY 19-8004 (5 mg once daily), a novel orally administered PDE4 inhibitor, on trough FEV1 and markers of inflammation in induced sputum in patients with asthma or chronic obstructive pulmonary disease (COPD)."9.10Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). ( Benschop, N; Gauw, SA; Grootendorst, DC; Hiemstra, PS; Rabe, KF; Sterk, PJ, 2003)
"Low-intensity exercise suppresses whole-body protein and urea turnover in COPD patients with emphysema and needs to be considered when maximal anabolism is targeted through a combination of exercise and nutrition."7.72Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema. ( Deutz, NE; Engelen, MP; Mostert, R; Schols, AM; Wouters, EF, 2003)
" The purpose of this study was to determine the intrapulmonary profile of high-dose (750 mg) levofloxacin in patients during an acute exacerbation of chronic bronchitis (AECB)."5.16Bronchopulmonary pharmacokinetic and pharmacodynamic profiles of levofloxacin 750 mg once daily in adults undergoing treatment for acute exacerbation of chronic bronchitis. ( Baughman, RP; Nicolau, DP; Sutherland, C; Winget, D, 2012)
" We examined the effect of 1 week treatment with BAY 19-8004 (5 mg once daily), a novel orally administered PDE4 inhibitor, on trough FEV1 and markers of inflammation in induced sputum in patients with asthma or chronic obstructive pulmonary disease (COPD)."5.10Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). ( Benschop, N; Gauw, SA; Grootendorst, DC; Hiemstra, PS; Rabe, KF; Sterk, PJ, 2003)
"Low-intensity exercise suppresses whole-body protein and urea turnover in COPD patients with emphysema and needs to be considered when maximal anabolism is targeted through a combination of exercise and nutrition."3.72Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema. ( Deutz, NE; Engelen, MP; Mostert, R; Schols, AM; Wouters, EF, 2003)
"In asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis, increased arginase activity in the airways may contribute to obstruction and hyperresponsiveness of the airways by inducing a reduction in the production of bronchodilatory nitric oxide (NO) that results from its competition with constitutive (cNOS) and inducible (iNOS) NO synthases for their common substrate."2.44Arginase and pulmonary diseases. ( Maarsingh, H; Meurs, H; Pera, T, 2008)
"In patients with COPD, only serum creatinine was higher (81."1.48Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis. ( Döme, B; Fábián, K; Fejes, D; Kakuk, T; Moldvay, J; Pipek, O; Prés, L; Puskás, R; Rojkó, L; Szállási, Z; Szegedi, Z, 2018)
"Hospitalization for exacerbation of COPD is associated with a high risk of mortality."1.37Predicting early mortality in acute exacerbation of chronic obstructive pulmonary disease using the CURB65 score. ( Chang, CL; Hancox, RJ; Karalus, NC; McLachlan, JD; Mills, GD; Sullivan, GD, 2011)
"Chronic obstructive pulmonary disease (COPD) has a rising global incidence and acute exacerbation of COPD (AECOPD) carries a high health-care economic burden."1.37Routine laboratory tests can predict in-hospital mortality in acute exacerbations of COPD. ( Andrews, NP; Asiimwe, AC; Brims, FJ; Chauhan, AJ; Higgins, BR; Kilburn, SA; Prytherch, DR, 2011)
"Urea is a non-volatile molecule ex vivo and EBC urea depends on its concentrations in plasma."1.35Urea in exhaled breath condensate of uraemics and patients with chronic airway diseases. ( Acampa, O; Andreoli, R; Bertorelli, G; Corradi, M; David, S; Folesani, G; Franchini, I; Goldoni, M; Manini, P, 2008)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Kaviani, A1
Khansari Nejad, N1
Akour, A1
AlMuhaissen, SA1
Nusair, MB1
Al-Tammemi, AB1
Mahmoud, NN1
Jalouqa, S1
Alrawashdeh, MN1
Shanahan, JP1
Moore, CM1
Kampf, JW1
Szymczak, NK1
Guo, J1
Wang, H1
Luo, Y1
An, H1
Zhang, Z2
Liu, G1
Li, J1
Metcalfe, GD1
Smith, TW1
Hippler, M1
Ayala Izurieta, JE1
Márquez, CO1
García, VJ1
Jara Santillán, CA1
Sisti, JM1
Pasqualotto, N1
Van Wittenberghe, S1
Delegido, J1
Kubo, Y1
Kitagawa, Y1
Miyazaki, T1
Sohda, M1
Yamaji, T1
Sakai, M1
Saeki, H1
Nemoto, K1
Oyama, T2
Muto, M1
Takeuchi, H1
Toh, Y1
Matsubara, H1
Mano, M1
Kono, K1
Kato, K1
Yoshida, M1
Kawakubo, H1
Booka, E1
Yamatsuji, T1
Kato, H1
Ito, Y1
Ishikawa, H1
Ishihara, R1
Tsushima, T1
Kawachi, H1
Kojima, T1
Kuribayashi, S1
Makino, T1
Matsuda, S1
Doki, Y1
Ma, P1
Tang, X1
Zhang, L2
Wang, X1
Wang, W1
Zhang, X1
Wang, S2
Zhou, N1
Dodd, J1
Jordan, R1
Makhlina, M1
Pesco Koplowitz, L1
Koplowitz, B1
Barnett, K1
Yang, WH1
Spana, C1
Buchanan, SW1
Mafa-Attoye, T1
Dunfield, K1
Thevathasan, NV1
Isaac, ME1
Wu, X2
Huang, JW1
Su, BK1
Yuan, L1
Zheng, WQ1
Zhang, H2
Zheng, YX1
Zhu, W1
Chou, PT1
Manso, AP1
De Morais, DC1
Yamamoto, K1
Owen, G1
de Carvalho, RM1
Palma-Dibb, RG1
Brown, JC1
Yang, S1
Mire, EF1
Miele, L1
Ochoa, A1
Zabaleta, J1
Katzmarzyk, PT1
Moi, CT1
Bhowmick, S1
Qureshi, M1
Wang, K1
Feng, B1
Yang, Y1
Chen, Y1
Wang, Y2
Yang, L1
Jiang, K1
James, TD1
Chaturvedi, V1
Postiglione, WM1
Chakraborty, RD1
Yu, B1
Tabiś, W1
Hameed, S1
Biniskos, N1
Jacobson, A1
Zhou, H1
Greven, M1
Ferry, VE1
Leighton, C1
Wu, F1
Lei, H1
Chen, G1
Chen, C1
Song, Y1
Cao, Z1
Zhang, C2
Zhou, J1
Lu, Y1
Pappone, C1
Santinelli, V1
Mecarocci, V1
Tondi, L1
Ciconte, G1
Manguso, F1
Sturla, F1
Vicedomini, G1
Micaglio, E1
Anastasia, L1
Pica, S1
Camporeale, A1
Lombardi, M1
Shieh, PB1
Elfring, G1
Trifillis, P1
Santos, C1
Peltz, SW1
Parsons, JA1
Apkon, S1
Darras, BT1
Campbell, C1
McDonald, CM1
Galaviz, KI1
Shah, NS1
Gutierrez, M1
Collins, LF1
Lahiri, CD1
Moran, CA1
Szabo, B1
Sumitani, J1
Rhodes, J1
Marconi, VC1
Nguyen, ML1
Cantos, VD1
Armstrong, WS1
Colasanti, JA1
Tanwar, Y1
Singh, C1
Chakrabarty, S1
Fábián, K1
Puskás, R1
Kakuk, T1
Prés, L1
Fejes, D1
Szegedi, Z1
Rojkó, L1
Szállási, Z1
Döme, B1
Pipek, O1
Moldvay, J1
Koskela, HO1
Salonen, PH1
Niskanen, L1
Folesani, G1
Corradi, M1
Goldoni, M1
Manini, P1
Acampa, O1
Andreoli, R1
Bertorelli, G1
David, S1
Franchini, I1
Chang, CL1
Sullivan, GD1
Karalus, NC1
Mills, GD1
McLachlan, JD1
Hancox, RJ1
Esther, CR1
Lazaar, AL1
Bordonali, E1
Qaqish, B1
Boucher, RC1
Asiimwe, AC1
Brims, FJ1
Andrews, NP1
Prytherch, DR1
Higgins, BR1
Kilburn, SA1
Chauhan, AJ1
Nicolau, DP1
Sutherland, C1
Winget, D1
Baughman, RP1
Engelen, MP1
Deutz, NE1
Mostert, R1
Wouters, EF1
Schols, AM1
Grootendorst, DC1
Gauw, SA1
Benschop, N1
Sterk, PJ1
Hiemstra, PS1
Rabe, KF1
Esposito, C1
De Mauri, A1
Vitulo, P1
Oggionni, T1
Cornacchia, F1
Valentino, R1
Grosjean, F1
Torreggiani, M1
Dal Canton, A1
Maarsingh, H1
Pera, T1
Meurs, H1
Kirkham, S1
Sheehan, JK1
Knight, D1
Richardson, PS1
Thornton, DJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Non-Invasive Doppler Ultrasound For Assessing Patients With Chronic Obstructive Pulmonary Disease: A Prospective Observational Study[NCT02329522]200 participants (Anticipated)Observational2014-02-28Active, not recruiting
Phase I/II Randomized, Double-blind, Placebo-controlled Cross-over Study of Prednisone on Airway Inflammatory Response to Inhaled Wood Smoke.[NCT03861390]Phase 1/Phase 214 participants (Anticipated)Interventional2019-03-22Recruiting
Phase I/II Randomized Cross-over Study of Hypertonic Saline on Airway Inflammatory Response to Inhaled Wood Smoke[NCT03851406]14 participants (Anticipated)Interventional2019-08-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for urea and Airflow Obstruction, Chronic

ArticleYear
    Biomaterial investigations in dentistry, 2021, Volume: 8, Issue:1

    Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes

2021
Arginase and pulmonary diseases.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:2

    Topics: Animals; Arginase; Arginine; Asthma; Cystic Fibrosis; Disease Models, Animal; Humans; Hypertension,

2008

Trials

2 trials available for urea and Airflow Obstruction, Chronic

ArticleYear
Bronchopulmonary pharmacokinetic and pharmacodynamic profiles of levofloxacin 750 mg once daily in adults undergoing treatment for acute exacerbation of chronic bronchitis.
    Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve;

2012
Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19-8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD).
    Pulmonary pharmacology & therapeutics, 2003, Volume: 16, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Asthma; B

2003

Other Studies

10 other studies available for urea and Airflow Obstruction, Chronic

ArticleYear
Comparison of Serum Uric Acid Levels in Patients with Stable Chronic Obstructive Pulmonary Disease and Patients with Acute Exacerbation.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Creatinine; Cross-Sectional Studies; Humans; Hypoxia; Pulmonary Disease, Chronic Obstructive; Urea;

2022
Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Neoplasms; Comorbidity; Creat

2018
Hyperglycaemia during exacerbations of asthma and chronic obstructive pulmonary disease.
    The clinical respiratory journal, 2013, Volume: 7, Issue:4

    Topics: Acute Disease; Aged; Aged, 80 and over; Asthma; Blood Glucose; C-Reactive Protein; Comorbidity; Diab

2013
Urea in exhaled breath condensate of uraemics and patients with chronic airway diseases.
    Acta bio-medica : Atenei Parmensis, 2008, Volume: 79 Suppl 1

    Topics: Adult; Asthma; Breath Tests; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Pulmonary Disease,

2008
Predicting early mortality in acute exacerbation of chronic obstructive pulmonary disease using the CURB65 score.
    Respirology (Carlton, Vic.), 2011, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Confusion; Disease Progression; Female; Hospi

2011
Elevated airway purines in COPD.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Adenosine; Adenosine Monophosphate; Aged; Biomarkers; Breath Tests; Case-Control Studies; Exhalation

2011
Elevated airway purines in COPD.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Adenosine; Adenosine Monophosphate; Aged; Biomarkers; Breath Tests; Case-Control Studies; Exhalation

2011
Elevated airway purines in COPD.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Adenosine; Adenosine Monophosphate; Aged; Biomarkers; Breath Tests; Case-Control Studies; Exhalation

2011
Elevated airway purines in COPD.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Adenosine; Adenosine Monophosphate; Aged; Biomarkers; Breath Tests; Case-Control Studies; Exhalation

2011
Routine laboratory tests can predict in-hospital mortality in acute exacerbations of COPD.
    Lung, 2011, Volume: 189, Issue:3

    Topics: Aged; Aged, 80 and over; Algorithms; Biomarkers; Carbon Dioxide; Decision Support Techniques; Decisi

2011
Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema.
    The American journal of clinical nutrition, 2003, Volume: 77, Issue:4

    Topics: Aged; Body Composition; Body Mass Index; Emphysema; Exercise; Humans; Kinetics; Male; Middle Aged; P

2003
Risk factors for chronic renal dysfunction in lung transplant recipients.
    Transplantation, 2007, Dec-27, Volume: 84, Issue:12

    Topics: Adult; Age Factors; Blood Pressure; Comorbidity; Female; Humans; Hypertension, Pulmonary; Kidney Fai

2007
Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.
    The Biochemical journal, 2002, Feb-01, Volume: 361, Issue:Pt 3

    Topics: Asthma; Blotting, Western; Cystic Fibrosis; Dose-Response Relationship, Drug; Electrophoresis, Agar

2002