urea has been researched along with Adrenal Cortex Cancer in 6 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Results 63 patients with metastatic ACC, all of whom had previously failed systemic chemotherapy and only 2 of whom were mitotane-naïve, were dosed with oral nevanimibe at doses ranging from 1." | 2.94 | A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma. ( Chugh, R; Fassnacht, M; Habra, MA; Ijzerman, MM; Jafarinasabian, P; Kebebew, E; Kroiss, M; Lin, VH; Mohideen, P; Naing, A; Schneider, BJ; Smith, DC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Laha, D | 1 |
| Grant, RRC | 1 |
| Mishra, P | 1 |
| Boufraqech, M | 1 |
| Shen, M | 1 |
| Zhang, YQ | 1 |
| Hall, MD | 1 |
| Quezado, M | 1 |
| De Melo, MS | 1 |
| Del Rivero, J | 1 |
| Zeiger, M | 1 |
| Nilubol, N | 1 |
| Smith, DC | 1 |
| Kroiss, M | 1 |
| Kebebew, E | 1 |
| Habra, MA | 1 |
| Chugh, R | 1 |
| Schneider, BJ | 1 |
| Fassnacht, M | 1 |
| Jafarinasabian, P | 1 |
| Ijzerman, MM | 1 |
| Lin, VH | 1 |
| Mohideen, P | 1 |
| Naing, A | 1 |
| WOLFSON, WQ | 1 |
| DE FILIPPIS, V | 1 |
| TAYLOR, NM | 1 |
| SWEENY, DN | 1 |
| Ferriss, JB | 2 |
| Brown, JJ | 2 |
| Fraser, R | 2 |
| Lever, AF | 2 |
| Robertson, JI | 2 |
| Thuróczy, J | 1 |
| van Sluijs, FJ | 1 |
| Kooistra, HS | 1 |
| Voorhout, G | 1 |
| Mol, JA | 1 |
| van der Linde-Sipman, JS | 1 |
| Rijnberk, A | 1 |
| Beevers, DG | 1 |
| Davies, DL | 1 |
| Mason, P | 1 |
| Neville, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 1 Study of the Safety and Tolerability of ATR-101 in Adrenocortical Carcinoma[NCT01898715] | Phase 1 | 63 participants (Actual) | Interventional | 2013-08-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for urea and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Primary hyperaldosteronism.
Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; | 1981 |
1 trial available for urea and Adrenal Cortex Cancer
| Article | Year |
|---|---|
A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Female; Humans; Male; Middle Aged; | 2020 |
4 other studies available for urea and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Preclinical assessment of synergistic efficacy of MELK and CDK inhibitors in adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Animals; Apoptosis; beta Catenin; Caspase 3; Cel | 2022 |
Decreased blood urea levels after resection of adrenocortical tumor for Cushing's syndrome.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Blood; Cushing Syndrome; Humans; Urea | 1955 |
Multiple endocrine neoplasias in a dog: corticotrophic tumour, bilateral adrenocortical tumours, and pheochromocytoma.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; | 1998 |
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult | 1978 |