urea and Adenoma studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

Excerpt	Relevance	Reference
"Lung adenomas were induced in strain A mice by chronic treatment with N-nitroso compounds (given in drinking water) and with amines or ureas in food plus NaNO2 in drinking water."	7.65	Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. ( Cardesa, A; Mirvish, SS; Shubik, P; Wallcave, L, 1975)
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin."	7.65	Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972)
"Prostatic acid phosphatase was purified from prostatic adenomas."	3.66	Prostatic acid phosphatase, purification and iodination using Iodogen. ( Nustad, K; Skinningsrud, A, 1982)
"Lung adenomas were induced in strain A mice by chronic treatment with N-nitroso compounds (given in drinking water) and with amines or ureas in food plus NaNO2 in drinking water."	3.65	Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. ( Cardesa, A; Mirvish, SS; Shubik, P; Wallcave, L, 1975)
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin."	3.65	Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972)
"Thirteen of 15 parathyroid adenomas were localized by pre-operative scanning, but in five of them a false positive focus was also described."	1.26	Pre-operative localization of hyperfunctioning parathyroid tissue by parathyroid scintigraphy. ( Bischof-Delaloye, A; Burckhardt, P; Delaloye, B; Ruedi, B, 1976)
"Lymphomas were seen only at the higher dose when the animals were were young, at the beginning of the test."	1.26	Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea. ( Maronpot, RR; Narisawa, T; Weisburger, JH; Wong, CQ, 1976)
"At necropsy a parathyroid carcinoma infiltrated the thyroid at the site of the previous operation and there was a solitary hepatic metastasis."	1.25	Recurrent hyperparathyroidism due to parathyroid carcinoma. ( Ellis, HA; Floyd, M; Herbert, FK, 1971)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (91.67)	18.7374
1990's	1 (2.78)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Long, Y	1
Sanchez-Espiridion, B	1
Lin, M	1
White, L	1
Mishra, L	1
Raju, GS	1
Kopetz, S	1
Eng, C	1
Hildebrandt, MAT	1
Chang, DW	1
Ye, Y	1
Liang, D	1
Wu, X	1
Peper, JGK	1
Srbljin, S	1
van der Zant, FM	1
Knol, RJJ	1
Wondergem, M	1
KOSTENKO, SN	1
Fujii, K	1
Nomoto, K	1
Ferriss, JB	5
Brown, JJ	5
Fraser, R	5
Lever, AF	5
Robertson, JI	5
Skinningsrud, A	1
Nustad, K	1
Kelly, DF	1
Laws, ER	1
Fossett, D	1
Haywood, E	2
Davies, DL	3
Kay, AW	1
Owen, K	1
Peart, WS	1
Beevers, DG	2
Mason, P	1
Neville, AM	1
Burckhardt, P	1
Bischof-Delaloye, A	1
Ruedi, B	1
Delaloye, B	1
Tree, M	1
Mirvish, SS	3
Lange, HH	1
Renner, E	1
Cardesa, A	1
Wallcave, L	1
Shubik, P	1
Narisawa, T	1
Wong, CQ	1
Maronpot, RR	1
Weisburger, JH	1
Fraser, P	1
Healy, M	1
Rose, N	1
Watson, L	2
Ellis, HA	1
Floyd, M	1
Herbert, FK	1
Frei, JV	3
Terracini, B	1
Testa, MC	1
Barraclough, BH	1
Coupland, GA	1
Burden, RP	1
Booth, LJ	1
Aber, GM	1
Tekeli, S	1
Biava, CG	1
Price, JM	1
Porter, R	1
Crombie, AL	1
Lechner, K	1
Regele, H	1
Waldhäusl, W	1
Karobath, H	1
Greenblatt, M	1
Kommineni, VR	1
Henkin, RI	1
Bradley, DF	1
Eckert, H	1
Seidler, E	1
Shabad, LM	1
Mennel, HD	1
Rakieten, N	1
Gordon, BS	1
Cooney, DA	1
Davis, RD	1
Schein, PS	1
Jobst, K	1

Trial	Enrollment	Study Type	Start Date	Status
Post-Operative Water Load Following Transsphenoidal Pituitary Surgery[NCT02727686]	30 participants (Actual)	Interventional	2016-03-07	Completed
Prospective Assessment of The Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation[NCT01267747]	411 participants (Actual)	Observational	2015-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Primary hyperaldosteronism. Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3 Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged;	1981
Blocking the formation of N-nitroso compounds with ascorbic acid in vitro and in vivo. Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258 Topics: Adenoma; Amines; Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Female; Liver; Lung Neopl	1975
Primary hyperparathyroidism. Clinics in endocrinology and metabolism, 1974, Volume: 3, Issue:2 Topics: Adenoma; Age Factors; Alkaline Phosphatase; Analysis of Variance; Calcium; Carcinoma; Female; Homeos	1974
From nitrosamines to nitrosoureas and nitrosoquanidines. Food and cosmetics toxicology, 1971, Volume: 9, Issue:5 Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Drinking; Food	1971

Article	Year
Global and targeted serum metabolic profiling of colorectal cancer progression. Cancer, 2017, Oct-15, Volume: 123, Issue:20 Topics: Adenoma; Adult; Aged; Caffeine; Case-Control Studies; Chromatography, Liquid; Colonic Polyps; Colore	2017
High 18Fluor-DCFPyL Uptake in Adrenal Adenomas. Clinical nuclear medicine, 2017, Volume: 42, Issue:11 Topics: Adenoma; Adrenal Gland Neoplasms; Aged; Biological Transport; Humans; Lysine; Male; Positron Emissio	2017
[Urea clearance as a kidney function test in prostate adenoma]. Laboratornoe delo, 1962, Volume: 8 Topics: Adenoma; Humans; Kidney Function Tests; Male; Prostatic Hyperplasia; Urea; Urography	1962
Tumor induction by a single subcutaneous injection of 1-butyl-1-nitrosourea or 1-butylurea in newborn mice. Cancer letters, 1983, Volume: 18, Issue:3 Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Carcinogens; Female; Injections, Subcutaneous; L	1983
Prostatic acid phosphatase, purification and iodination using Iodogen. Clinica chimica acta; international journal of clinical chemistry, 1982, Mar-26, Volume: 120, Issue:1 Topics: Acid Phosphatase; Adenoma; Chromatography; Drug Stability; Humans; Imidazoles; Immunoelectrophoresis	1982
Delayed hyponatremia after transsphenoidal surgery for pituitary adenoma. Report of nine cases. Journal of neurosurgery, 1995, Volume: 83, Issue:2 Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Hyponatremia; Male; Midd	1995
Results of adrenal surgery in patients with hypertension, aldosterone excess, and low plasma renin concentration. British medical journal, 1975, Jan-18, Volume: 1, Issue:5950 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Angiotensin II; Blood Pres	1975
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism. American heart journal, 1978, Volume: 95, Issue:3 Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult	1978
Pre-operative localization of hyperfunctioning parathyroid tissue by parathyroid scintigraphy. Acta endocrinologica, 1976, Volume: 81, Issue:2 Topics: Adenoma; Adult; Aged; Alkaline Phosphatase; Calcium; Creatinine; Female; Humans; Hyperparathyroidism	1976
Renal abnormalities and vascular complications in primary hyperaldosteronism. Evidence on tertiary hyperaldosteronism. The Quarterly journal of medicine, 1976, Volume: 45, Issue:179 Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Female; Humans; Hyperaldosteronism; Hypertension, Mal	1976
[Pre-renal failure due to villous adenoma of the colon]. Deutsche medizinische Wochenschrift (1946), 1975, Feb-07, Volume: 100, Issue:6 Topics: Acute Kidney Injury; Adenoma; Aged; Aldosterone; Chlorides; Colonic Neoplasms; Creatinine; Humans; M	1975
Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. Journal of the National Cancer Institute, 1975, Volume: 55, Issue:3 Topics: Adenoma; Amines; Animals; Ascorbic Acid; Caffeine; Dose-Response Relationship, Drug; Gallic Acid; Lu	1975
Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea. Cancer research, 1976, Volume: 36, Issue:2 Pt 1 Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Dose-Response Relatio	1976
Discriminant functions in differential diagnosis of hypercalcaemia. Lancet (London, England), 1971, Jun-26, Volume: 1, Issue:7713 Topics: Adenoma; Alkaline Phosphatase; Bicarbonates; Calcium; Carcinoma; Chlorides; Computers; Diagnosis, Di	1971
Recurrent hyperparathyroidism due to parathyroid carcinoma. Journal of clinical pathology, 1971, Volume: 24, Issue:7 Topics: Adenoma; Adult; Autopsy; Calcium; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hyperplasia; H	1971
Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds. Cancer research, 1970, Volume: 30, Issue:1 Topics: Adenoma; Animals; Animals, Newborn; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Carcinoma, Hep	1970
Carcinogenicity of a single administration of N-nitrosomethylurea: a comparison between newborn and 5-week-old mice and rats. British journal of cancer, 1970, Volume: 24, Issue:3 Topics: Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Female; Gastrointestinal	1970
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. British medical journal, 1972, Jun-24, Volume: 2, Issue:5816 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pr	1972
Acute pancreatitis: a review. The Australian and New Zealand journal of surgery, 1972, Volume: 41, Issue:3 Topics: Abdominal Injuries; Acute Disease; Adenoma; Adult; Aged; Alcohol Drinking; Amylases; Australia; Bili	1972
The diagnostic and therapeutic value of spironolactone in patients with systemic hypertension. Nephron, 1973, Volume: 9, Issue:3 Topics: Acid-Base Equilibrium; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Press	1973
The carcinogenic activity of 3-hydroxymethyl-1-((3-(5-nitro-2-furyl)allydidene)amino)-hydantoin in rats. Cancer research, 1973, Volume: 33, Issue:11 Topics: Adenocarcinoma; Adenoma; Allyl Compounds; Animals; Carcinogens; Diet; Female; Hydantoins; Kidney; Ki	1973
Corneal calcification as a presenting and diagnostic sign in hyperparathyroidism. The British journal of ophthalmology, 1973, Volume: 57, Issue:9 Topics: Adenoma; Alkaline Phosphatase; Barium Sulfate; Calcinosis; Calcium; Cornea; Eye Manifestations; Fema	1973
[Consumption coagulopathy in metastatic prostatic carcinoma]. Acta haematologica, 1968, Volume: 40, Issue:1 Topics: Acid Phosphatase; Adenoma; Aged; Alkaline Phosphatase; Bilirubin; Blood Coagulation Disorders; Blood	1968
Nitrosamide formation in vivo: induction of lung adenomas in Swiss mice by concurrent feeding of nitrite and methylurea or ethylurea. Journal of the National Cancer Institute, 1972, Volume: 48, Issue:5 Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Female; Kinetics; Lung Neoplasms; Lymphoma; Male; Mic	1972
On the mechanism of action of carbohydrate active steroids on tastant detection and recognition. UCLA forum in medical sciences, 1972, Volume: 15 Topics: Addison Disease; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insufficiency; Ad	1972
Tumour induction by low molecular weight alkylating agents. Chemico-biological interactions, 1971, Volume: 3, Issue:2 Topics: Adenoma; Alkanes; Alkylating Agents; Animals; Carcinogens; DNA Replication; DNA, Neoplasm; Guanine;	1971
[Carcinogenic effect of methylnitrosourea in the mouse]. Archiv fur Geschwulstforschung, 1971, Volume: 38, Issue:1 Topics: Adenoma; Administration, Oral; Animals; Bronchial Neoplasms; Carcinogens; Injections, Intravenous; M	1971
[Transplacental effect of blastomogenic substances. Some further studies on organ cultures]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:7 Topics: Adenoma; Animals; Benz(a)Anthracenes; Biphenyl Compounds; Carcinogens; Culture Techniques; Embryo, M	1969
[Morphology of hypophyseal tumors in rats]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:7 Topics: Adenoma; Animals; Carcinogens; Cyclophosphamide; Male; Nitroso Compounds; Pituitary Gland; Pituitary	1969
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea. International journal of cancer, 1971, May-15, Volume: 7, Issue:3 Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung	1971
Renal tumorigenic action of streptozotocin (NSC-85998) in rats. Cancer chemotherapy reports, 1968, Volume: 52, Issue:5 Topics: Acrylates; Adenoma; Animals; Anti-Bacterial Agents; Female; Kidney Neoplasms; Male; Nitroso Compound	1968
On the DNA and histone content of N-nitrosomethylurea induced rat tumours. Neoplasma, 1969, Volume: 16, Issue:1 Topics: Adenoma; Aneuploidy; Animals; Brain Neoplasms; Bronchial Neoplasms; Carcinoma; DNA; DNA, Neoplasm; F	1969

urea and Adenoma

Research Excerpts

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