urea has been researched along with Acute Myelogenous Leukemia in 21 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) suppress normal hematopoietic activity in part by enabling a pathogenic inflammatory milieu in the bone marrow." | 1.43 | Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia. ( Assal, A; Bachegowda, L; Bartenstein, M; Bhagat, T; Bhattacharyya, S; Boultwood, J; Brown, S; Burgess, LE; Chantry, D; Garrus, J; Giricz, O; Gordon-Mitchell, S; Gross, S; Guha, C; Hogeland, G; Mantzaris, I; Morrone, K; Munson, M; Nwankwo, G; Pellagatti, A; Platanias, L; Pradhan, K; Ramachandra, N; Rizzi, J; Rodriguez, M; Schinke, C; Shahnaz, S; Shastri, A; Steidl, U; Sukrithan, V; Verma, A; Winski, SL; Wollenberg, L; Wright, D; Yu, Y; Zou, Y, 2016) |
| "In patients with acute myeloid leukemia, a 41 kDa glycoprotein appears in the urine during remission induction chemotherapy." | 1.29 | Limited proteolysis of alpha 1-proteinase inhibitor (alpha 1-PI) in acute leukemia: studies on the resulting fragments and implication for the structure of the inactivated inhibitor. ( Dengler, R; Emmerich, B; Lottspeich, F; Mast, AE; Oberthür, W, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YC | 1 |
| Shi, YJ | 1 |
| Wang, LJ | 2 |
| Chiou, JT | 1 |
| Huang, CH | 1 |
| Chang, LS | 1 |
| Zhong, Y | 1 |
| Qiu, RZ | 1 |
| Sun, SL | 1 |
| Zhao, C | 1 |
| Fan, TY | 1 |
| Chen, M | 1 |
| Li, NG | 1 |
| Shi, ZH | 1 |
| Lin, WH | 2 |
| Hsu, JT | 2 |
| Hsieh, SY | 2 |
| Chen, CT | 2 |
| Song, JS | 1 |
| Yen, SC | 2 |
| Hsu, T | 1 |
| Lu, CT | 1 |
| Chen, CH | 2 |
| Chou, LH | 2 |
| Yang, YN | 1 |
| Chiu, CH | 2 |
| Chen, CP | 2 |
| Tseng, YJ | 1 |
| Yen, KJ | 2 |
| Yeh, CF | 1 |
| Chao, YS | 2 |
| Yeh, TK | 2 |
| Jiaang, WT | 2 |
| Huang, CT | 1 |
| Kao, LC | 1 |
| Ma, S | 2 |
| Yang, LL | 2 |
| Niu, T | 1 |
| Cheng, C | 2 |
| Zhong, L | 1 |
| Zheng, MW | 1 |
| Xiong, Y | 1 |
| Li, LL | 2 |
| Xiang, R | 1 |
| Chen, LJ | 1 |
| Zhou, Q | 1 |
| Wei, YQ | 1 |
| Yang, SY | 2 |
| Bachegowda, L | 1 |
| Morrone, K | 1 |
| Winski, SL | 1 |
| Mantzaris, I | 1 |
| Bartenstein, M | 1 |
| Ramachandra, N | 1 |
| Giricz, O | 1 |
| Sukrithan, V | 1 |
| Nwankwo, G | 1 |
| Shahnaz, S | 1 |
| Bhagat, T | 1 |
| Bhattacharyya, S | 1 |
| Assal, A | 1 |
| Shastri, A | 1 |
| Gordon-Mitchell, S | 1 |
| Pellagatti, A | 1 |
| Boultwood, J | 1 |
| Schinke, C | 1 |
| Yu, Y | 1 |
| Guha, C | 1 |
| Rizzi, J | 1 |
| Garrus, J | 1 |
| Brown, S | 1 |
| Wollenberg, L | 1 |
| Hogeland, G | 1 |
| Wright, D | 1 |
| Munson, M | 1 |
| Rodriguez, M | 1 |
| Gross, S | 1 |
| Chantry, D | 1 |
| Zou, Y | 1 |
| Platanias, L | 1 |
| Burgess, LE | 1 |
| Pradhan, K | 1 |
| Steidl, U | 1 |
| Verma, A | 1 |
| Didier, C | 1 |
| Demur, C | 1 |
| Grimal, F | 1 |
| Jullien, D | 1 |
| Manenti, S | 1 |
| Ducommun, B | 1 |
| Li, GB | 1 |
| Zou, C | 1 |
| Zhou, S | 1 |
| Sun, QZ | 1 |
| Chen, X | 1 |
| Feng, S | 1 |
| Zhang, L | 1 |
| Su, X | 1 |
| Liu, S | 1 |
| Knapp, AR | 1 |
| Parthun, MR | 1 |
| Marcucci, G | 1 |
| Freitas, MA | 1 |
| Kien, CL | 1 |
| Camitta, BM | 1 |
| Buckman, R | 1 |
| Cuzick, J | 1 |
| Galton, DA | 1 |
| Dengler, R | 1 |
| Lottspeich, F | 1 |
| Oberthür, W | 1 |
| Mast, AE | 1 |
| Emmerich, B | 1 |
| Pavelić, K | 1 |
| Pekić, B | 1 |
| Mir, MA | 1 |
| Delamore, IW | 1 |
| Arfi, S | 1 |
| Baglin, A | 1 |
| Alterescu, R | 1 |
| Goguel, A | 1 |
| Fendler, JP | 1 |
| Fritel, D | 1 |
| Nissen, NI | 1 |
| Dano, K | 1 |
| Vogler, WR | 1 |
| Zubrod, CG | 1 |
| Holland, JF | 1 |
| Harrod, EK | 1 |
| Cortner, JA | 1 |
| Tibbling, G | 1 |
2 reviews available for urea and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.
Topics: fms-Like Tyrosine Kinase 3; Humans; Indoles; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Py | 2020 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; | 1970 |
1 trial available for urea and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.
Topics: Age Factors; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Clinical Trials as Topic; Cytar | 1971 |
18 other studies available for urea and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
GSK3β suppression inhibits MCL1 protein synthesis in human acute myeloid leukemia cells.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation | 2021 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3).
Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cell Proliferation; Drug Discovery; fm | 2013 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamide | 2014 |
SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, T | 2015 |
Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Topics: Angiopoietin-1; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; | 2016 |
Evaluation of checkpoint kinase targeting therapy in acute myeloid leukemia with complex karyotype.
Topics: Aged; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Humans; Karyotype; L | 2012 |
Structure-activity relationship studies of pyrazolo[3,4-d]pyrimidine derivatives leading to the discovery of a novel multikinase inhibitor that potently inhibits FLT3 and VEGFR2 and evaluation of its activity against acute myeloid leukemia in vitro and in
Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Antineoplastic Agents; Apoptosis; C | 2013 |
Histone H4 N-terminal acetylation in Kasumi-1 cells treated with depsipeptide determined by acetic acid-urea polyacrylamide gel electrophoresis, amino acid coded mass tagging, and mass spectrometry.
Topics: Acetic Acid; Acetylation; Cell Line; Cell Line, Tumor; Chromatography, Liquid; Electrophoresis, Poly | 2007 |
Increased whole-body protein turnover in sick children with newly diagnosed leukemia or lymphoma.
Topics: Ammonia; Glycine; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Nitrogen | 1983 |
Long-term survival in myelomatosis. A report to the MRC working party on leukaemia in adults.
Topics: Aged; Bence Jones Protein; Cyclophosphamide; Female; Hemoglobins; Humans; Immunoglobulin G; Kidney F | 1982 |
Limited proteolysis of alpha 1-proteinase inhibitor (alpha 1-PI) in acute leukemia: studies on the resulting fragments and implication for the structure of the inactivated inhibitor.
Topics: alpha 1-Antitrypsin; Amino Acid Sequence; Amino Acids; Chemotaxis, Leukocyte; Chromatography, Gel; E | 1995 |
Electrophoretic distribution and dissociation into subunits of lactate dehydrogenase derived from human myeloid leukemia cells before and after induction of differentiation.
Topics: Adult; Aged; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Humans; Isoenzymes; L-Lactat | 1986 |
Hyponatraemia syndrome in acute myeloid leukaemia.
Topics: Adult; Ampicillin; Blood Cell Count; Body Weight; Bone Marrow Cells; Chlorides; Cloxacillin; Cytarab | 1974 |
[Acute kidney failure in acute leukemia].
Topics: Acute Kidney Injury; Adult; Aged; Blood Cell Count; Female; Furosemide; Humans; Leukemia; Leukemia, | 1973 |
Treatment of the acute leukemias.
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leuke | 1967 |
Summary: recent advances in the treatment of acute leukemia and Burkitt's tumor.
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; H | 1967 |
Prolonged survival of lymphocytes with chromosomal defects in children treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Chromosome Aberrations; C | 1968 |
Glycerol and free fatty acid turnover in leukaemia and hyperthyroidism.
Topics: Adult; Blood Glucose; Carbon Isotopes; Colorimetry; Fatty Acids, Nonesterified; Female; Fluorometry; | 1970 |