Page last updated: 2024-10-21

urea and Acute Hepatic Failure

urea has been researched along with Acute Hepatic Failure in 26 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
"They are used in patients with acute liver failure (ALF) and acute-on-chronic liver failure."2.72Artificial liver support systems. ( Froghi, S; Tandon, R, 2021)
"When hyperammonemia is not thought to be the result of liver failure, treatment for an occult disorder of metabolism must begin prior to the confirmation of an etiology."2.44Hyperammonemia in the ICU. ( Clay, AS; Hainline, BE, 2007)
"Acute liver failure is associated with mortality of around 50%."2.41Splanchnic circulation and metabolism in patients with acute liver failure. ( Clemmesen, O, 2002)
"When treated with serum from an acute liver failure patient, rat hepatocyte monoculture showed reduction of cell viability and loss of liver-specific functions."1.38Maintenance of rat hepatocytes under inflammation by coculture with human orbital fat-derived stem cells. ( Chen, X; Liu, T; Liu, Y; Wang, Y; Zhang, S, 2012)
"In patients with acute liver failure, hyperammonemia is associated with cerebral herniation."1.31Splanchnic and leg exchange of amino acids and ammonia in acute liver failure. ( Clemmesen, JO; Kondrup, J; Ott, P, 2000)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's16 (61.54)29.6817
2010's7 (26.92)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Zhou, GP1
Li, SP1
Jiang, YZ1
Sun, J1
Tan, YL1
Zeng, ZG1
Wei, L2
Qu, W1
Sun, LY1
Zhu, ZJ1
Tandon, R1
Froghi, S1
Mondal, P1
Trigun, SK1
Li, S1
Sun, Z1
Lv, G1
Guo, X1
Zhang, Y1
Yu, W1
Wang, W1
Ma, X1
Feng, B1
Wu, SM1
Lv, S1
Liu, F1
Chen, HS1
Gao, Y1
Dong, FT1
Chen, Y1
Li, J1
Liu, X1
Zhao, W1
Wang, Y3
Wang, X1
Jung, A1
Korohoda, P1
Krisper, P1
Schneditz, D1
Teufel, U1
Weitz, J1
Flechtenmacher, C1
Prietsch, V1
Schmidt, J1
Hoffmann, GF1
Kölker, S1
Engelmann, G1
Chen, X1
Zhang, S1
Liu, T1
Liu, Y1
Lee, JH1
Lee, DH1
Park, JK1
Kim, SK1
Kwon, CH1
Lee, SK1
Nibourg, GA1
Hoekstra, R1
van der Hoeven, TV1
Ackermans, MT1
Hakvoort, TB1
van Gulik, TM2
Chamuleau, RA2
Mundt, A1
Puhl, G1
Müller, A1
Sauer, I1
Müller, C1
Richard, R1
Fotopoulou, C1
Doll, R1
Gäbelein, G1
Höhn, W1
Hofbauer, R1
Neuhaus, P1
Gerlach, J1
Clemmesen, O1
Abrahamse, SL1
van de Kerkhove, MP1
Sosef, MN1
Hartman, R1
Lorenti, A1
Barbich, M1
de Santibáñes, M1
Ielpi, M1
Vazquez, JC1
Sorroche, P1
Argibay, P1
Filippi, C1
Keatch, SA1
Rangar, D1
Nelson, LJ1
Hayes, PC1
Plevris, JN1
Peng, CH1
Han, BS1
Gao, CY1
Ma, ZW1
Zhao, ZM1
Liu, H1
Zhang, GD1
Yang, MJ1
Gan, JH1
Zhou, XQ1
Qin, AL1
Luo, EP1
Zhao, WF1
Yu, H1
Xu, J1
Abu-Absi, SF1
Seth, G1
Narayanan, RA1
Groehler, K1
Lai, P1
Anderson, ML1
Sielaff, T1
Hu, WS1
Nagaki, M1
Naito, T1
Ohnishi, H1
Akaike, T1
Muto, Y1
Moriwaki, H1
Clay, AS1
Hainline, BE1
Yang, WS1
Tan, HK1
Lui, HF1
Chow, PK1
Choong, HL1
Wong, KS1
Matthew, HW1
Basu, S1
Peterson, WD1
Salley, SO1
Klein, MD1
Clemmesen, JO2
Kondrup, J2
Ott, P2
Nielsen, LB1
Larsen, FS1
De Bartolo, L1
Bader, A1

Reviews

4 reviews available for urea and Acute Hepatic Failure

ArticleYear
Artificial liver support systems.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:5

    Topics: Acute-On-Chronic Liver Failure; Bilirubin; Creatinine; Dialysis; Female; gamma-Glutamyltransferase;

2021
Splanchnic circulation and metabolism in patients with acute liver failure.
    Danish medical bulletin, 2002, Volume: 49, Issue:3

    Topics: Amino Acids; Ammonia; Cardiac Output; Fatty Acids, Nonesterified; Hemodynamics; Humans; Liver; Liver

2002
Hyperammonemia in the ICU.
    Chest, 2007, Volume: 132, Issue:4

    Topics: Acute Disease; Algorithms; Ammonia; Astrocytes; Brain; Brain Edema; Cerebral Hemorrhage; Critical Ca

2007
Review of a flat membrane bioreactor as a bioartificial liver.
    Annals of transplantation, 2001, Volume: 6, Issue:3

    Topics: Ammonia; Animals; Bioreactors; Biotransformation; Cells, Cultured; Diazepam; Hepatocytes; Humans; Li

2001

Other Studies

22 other studies available for urea and Acute Hepatic Failure

ArticleYear
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
    Journal of translational medicine, 2022, 10-20, Volume: 20, Issue:1

    Topics: Alanine Transaminase; Albumins; alpha 1-Antitrypsin; Animals; Aspartate Aminotransferases; Child; Cy

2022
Pannexin1 as a novel cerebral target in pathogenesis of hepatic encephalopathy.
    Metabolic brain disease, 2014, Volume: 29, Issue:4

    Topics: Ammonia; Brain; Connexins; Energy Metabolism; Glutamic Acid; Heart Arrest; Hepatic Encephalopathy; H

2014
Microencapsulated UCB cells repair hepatic injure by intraperitoneal transplantation.
    Cytotherapy, 2009, Volume: 11, Issue:8

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cell Differentiation; Cell P

2009
A novel scoring system for prognostic prediction in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure BALB/c mice.
    BMC gastroenterology, 2009, Dec-30, Volume: 9

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Disease Models, Animal; Galactosamine; Lipopolysaccharid

2009
Transplantation of immortalized human fetal hepatocytes prevents acute liver failure in 90% hepatectomized mice.
    Transplantation proceedings, 2010, Volume: 42, Issue:5

    Topics: Ammonia; Animals; Antigens, Polyomavirus Transforming; Cell Differentiation; Cell Division; Genetic

2010
Relationship between kinetics of albumin-bound bilirubin and water-soluble urea in extracorporeal blood purification.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Albumins; Bilirubin; End Stage Liver Disease; Extracorporeal Circulation; F

2012
High urgency liver transplantation in ornithine transcarbamylase deficiency presenting with acute liver failure.
    Pediatric transplantation, 2011, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Child, Preschool; Female; Hepatic Encephalopathy;

2011
Maintenance of rat hepatocytes under inflammation by coculture with human orbital fat-derived stem cells.
    Cellular & molecular biology letters, 2012, Volume: 17, Issue:2

    Topics: Adipose Tissue; Albumins; Animals; Cell Differentiation; Cell Survival; Coculture Techniques; Cytoch

2012
Effect of fulminant hepatic failure porcine plasma supplemented with essential components on encapsulated rat hepatocyte spheroids.
    Transplantation proceedings, 2012, Volume: 44, Issue:4

    Topics: Albumins; Alginates; Animals; Bioreactors; Cell Survival; Cells, Immobilized; Chitosan; Culture Medi

2012
Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-bioartificial liver.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:4

    Topics: Amino Acids; Ammonia; Animals; Apolipoprotein A-I; Cell Line, Tumor; Cytochrome P-450 CYP3A; Disease

2013
A method to assess biochemical activity of liver cells during clinical application of extracorporeal hybrid liver support.
    The International journal of artificial organs, 2002, Volume: 25, Issue:6

    Topics: Ammonia; Animals; Biochemistry; Bioreactors; Blood Flow Velocity; Extracorporeal Circulation; Glucos

2002
Treatment of acute liver failure in pigs reduces hepatocyte function in a bioartificial liver support system.
    The International journal of artificial organs, 2002, Volume: 25, Issue:10

    Topics: 7-Alkoxycoumarin O-Dealkylase; Ammonia; Animals; Butyrylcholinesterase; Cells, Cultured; Female; Hep

2002
Ammonium detoxification performed by porcine hepatocyte spheroids in a bioartificial liver for pediatric use: preliminary report.
    Artificial organs, 2003, Volume: 27, Issue:7

    Topics: Ammonia; Animals; Child; Diazepam; Equipment Design; Hepatocytes; Humans; Liver Failure, Acute; Live

2003
Improvement of C3A cell metabolism for usage in bioartificial liver support systems.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Albumins; Animals; Cell Line, Tumor; Cells, Cultured; Culture Media; Galactose; Gluconeogenesis; Hep

2004
[Study on the interface of human hepatocyte/micropore polypropylene ultrafiltration membrane].
    Zhonghua yi xue za zhi, 2004, Sep-02, Volume: 84, Issue:17

    Topics: Bioartificial Organs; Bioreactors; Cell Adhesion; Cells, Cultured; Hepatocytes; Humans; Liver Failur

2004
Hybrid artificial liver support system for treatment of severe liver failure.
    World journal of gastroenterology, 2005, Feb-14, Volume: 11, Issue:6

    Topics: Albumins; Animals; Animals, Suckling; Cell Survival; Cells, Cultured; Chronic Disease; Hepatocytes;

2005
Characterization of a hollow fiber bioartificial liver device.
    Artificial organs, 2005, Volume: 29, Issue:5

    Topics: Albumins; Animals; Blotting, Northern; Cell Culture Techniques; Cells, Cultured; Gene Expression; He

2005
Effects of plasma from patients with fulminant hepatic failure on function of primary rat hepatocytes in three-dimensional culture.
    Liver international : official journal of the International Association for the Study of the Liver, 2005, Volume: 25, Issue:5

    Topics: Albumins; Amino Acids; Animals; Cells, Cultured; Gluconeogenesis; Hepatocytes; Liver Failure, Acute;

2005
Albumin dialysis in critically ill patients: use versus omission of intradialytic heparin.
    Artificial organs, 2008, Volume: 32, Issue:5

    Topics: Adult; Aged; Albumins; Ammonia; Bilirubin; Contraindications; Creatinine; Dialysis; Dialysis Solutio

2008
Performance of plasma-perfused, microencapsulated hepatocytes: prospects for extracorporeal liver support.
    Journal of pediatric surgery, 1993, Volume: 28, Issue:11

    Topics: Albumins; Animals; Antipyrine; Carboxymethylcellulose Sodium; Cells, Cultured; Chitin; Chitosan; Cho

1993
Splanchnic and leg exchange of amino acids and ammonia in acute liver failure.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Adult; Alanine; Amino Acids; Ammonia; Blood Urea Nitrogen; Citrulline; Female; Femoral Artery; Femor

2000
Effects of high-volume plasmapheresis on ammonia, urea, and amino acids in patients with acute liver failure.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:4

    Topics: Adult; Amino Acids; Ammonia; Female; Humans; Liver Failure, Acute; Male; Plasmapheresis; Urea

2001