urea has been researched along with Acidemia Propionic in 5 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to determine whether N-carbamylglutamate (NCG) reduces plasma levels of ammonia and glutamine and increases the rate of ureagenesis in patients with propionic acidemia (PA)." | 9.14 | N-carbamylglutamate augments ureagenesis and reduces ammonia and glutamine in propionic acidemia. ( Ah Mew, N; Daikhin, Y; McCarter, R; Nissim, I; Tuchman, M; Yudkoff, M, 2010) |
| "The objective of this study was to determine whether N-carbamylglutamate (NCG) reduces plasma levels of ammonia and glutamine and increases the rate of ureagenesis in patients with propionic acidemia (PA)." | 5.14 | N-carbamylglutamate augments ureagenesis and reduces ammonia and glutamine in propionic acidemia. ( Ah Mew, N; Daikhin, Y; McCarter, R; Nissim, I; Tuchman, M; Yudkoff, M, 2010) |
| "Life-threatening hyperammonemia occurs in both inherited and acquired liver diseases affecting ureagenesis, the main pathway for detoxification of neurotoxic ammonia in mammals." | 4.12 | O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis. ( Arena, P; Attanasio, S; Boffa, I; Brunetti-Pierri, N; Cuomo, P; D'Alessio, AM; De Angelis, A; Desviat, LR; Ferenbach, AT; Häberle, J; Lipshutz, GS; Makris, G; Martínez-Pizarro, A; Motta, A; Nitzahn, M; Nusco, E; Paris, D; Pravata, VM; Richard, E; Rüfenacht, V; Soria, LR; van Aalten, DMF, 2022) |
| "Propionic acidemia is an inborn error of metabolism caused by a deficiency in the mitochondrial enzyme propionyl-CoA carboxylase that converts the propionyl CoA to methyl malonyl CoA." | 1.72 | Interorgan amino acid interchange in propionic acidemia: the missing key to understanding its physiopathology. ( Arrieta, F; Belanger-Quintana, A; Del Valle, M; Fernandez-Felix, BM; Garcia, F; Martinez-Pardo, M; Ruiz-Sala, P; Stanescu, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stanescu, S | 1 |
| Belanger-Quintana, A | 1 |
| Fernandez-Felix, BM | 1 |
| Ruiz-Sala, P | 1 |
| Del Valle, M | 1 |
| Garcia, F | 1 |
| Arrieta, F | 1 |
| Martinez-Pardo, M | 1 |
| Soria, LR | 1 |
| Makris, G | 1 |
| D'Alessio, AM | 1 |
| De Angelis, A | 1 |
| Boffa, I | 1 |
| Pravata, VM | 1 |
| Rüfenacht, V | 1 |
| Attanasio, S | 1 |
| Nusco, E | 1 |
| Arena, P | 1 |
| Ferenbach, AT | 1 |
| Paris, D | 1 |
| Cuomo, P | 1 |
| Motta, A | 1 |
| Nitzahn, M | 1 |
| Lipshutz, GS | 1 |
| Martínez-Pizarro, A | 1 |
| Richard, E | 1 |
| Desviat, LR | 1 |
| Häberle, J | 1 |
| van Aalten, DMF | 1 |
| Brunetti-Pierri, N | 1 |
| Chapman, KA | 1 |
| Collado, MS | 1 |
| Figler, RA | 1 |
| Hoang, SA | 1 |
| Armstrong, AJ | 1 |
| Cui, W | 1 |
| Purdy, M | 1 |
| Simmers, MB | 1 |
| Yazigi, NA | 1 |
| Summar, ML | 1 |
| Wamhoff, BR | 1 |
| Dash, A | 1 |
| Ah Mew, N | 1 |
| McCarter, R | 1 |
| Daikhin, Y | 1 |
| Nissim, I | 1 |
| Yudkoff, M | 1 |
| Tuchman, M | 1 |
| Scholl-Bürgi, S | 1 |
| Sass, JO | 1 |
| Zschocke, J | 1 |
| Karall, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate[NCT01341379] | Phase 2 | 0 participants (Actual) | Interventional | 2010-12-31 | Withdrawn (stopped due to Lack of funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for urea and Acidemia Propionic
| Article | Year |
|---|---|
Amino acid metabolism in patients with propionic acidaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Ammonia; Citric Acid Cycle; Diet; | 2012 |
1 trial available for urea and Acidemia Propionic
| Article | Year |
|---|---|
N-carbamylglutamate augments ureagenesis and reduces ammonia and glutamine in propionic acidemia.
Topics: Administration, Oral; Adolescent; Ammonia; Blood Chemical Analysis; Child; Child, Preschool; Confide | 2010 |
3 other studies available for urea and Acidemia Propionic
| Article | Year |
|---|---|
Interorgan amino acid interchange in propionic acidemia: the missing key to understanding its physiopathology.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Glutamine; Humans; Hyperammonem | 2022 |
O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.
Topics: Acetylglucosamine; Ammonia; Animals; Biocatalysis; Carbamoyl-Phosphate Synthase (Ammonia); Disease M | 2022 |
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Topics: Actins; Amino Acids, Branched-Chain; Ammonia; Carbon-Carbon Ligases; Cells, Cultured; Child; Fibrobl | 2016 |