Compounds > urea
Page last updated: 2024-10-21

urea and AIDS, Simian

urea has been researched along with AIDS, Simian in 12 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
" More MIV-150 was associated with cervical tissue 8 h after daily dosing of MIV-150/zinc acetate versus MIV-150, while comparable MIV-150 levels were associated with vaginal tissues and at 24 h."1.37An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques. ( Abraham, CJ; Aravantinou, M; Blanchard, J; Chudolij, A; Fernández-Romero, JA; Gettie, A; Hsu, M; Kenney, J; Kizima, L; Lifson, JD; Menon, R; Piatak, M; Robbiani, M; Rodriguez, A; Seidor, S; Singer, R; Zydowsky, TM, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Derby, N7
Aravantinou, M7
Kenney, J7
Ugaonkar, SR1
Wesenberg, A1
Wilk, J1
Kizima, L9
Rodriguez, A9
Zhang, S4
Mizenina, O3
Levendosky, K3
Cooney, ML5
Seidor, S10
Gettie, A11
Grasperge, B2
Blanchard, J11
Piatak, M8
Lifson, JD9
Fernández-Romero, J1
Zydowsky, TM12
Robbiani, M11
Hsu, M2
Keele, BF1
Krawczyk, N1
Abraham, CJ4
Jean-Pierre, N4
Piatak, MJ1
Fernández-Romero, JA11
Ouattara, LA1
Barnable, P4
Mawson, P3
Roberts, KD2
Teleshova, N6
Menon, R7
Pugach, P1
Villegas, G2
Ford, BE1
Paglini, G1
Calenda, G3
Ouattara, L1
Abraham, C1
Sperling, R1
Bonnaire, T1
Clark, MR1
Doncel, GF1
Singer, R5
Chudolij, A2
Goldman, D2

Other Studies

12 other studies available for urea and AIDS, Simian

ArticleYear
An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques.
    Drug delivery and translational research, 2017, Volume: 7, Issue:6

    Topics: Alphapapillomavirus; Animals; Antiviral Agents; Carrageenan; Contraceptive Agents, Female; Contracep

2017
Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Administration, Intravaginal; Animals; Anti-Infective Agents, Local; Drug Resistance, Viral; Female;

2014
MIV-150-containing intravaginal rings protect macaque vaginal explants against SHIV-RT infection.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:5

    Topics: Administration, Intravaginal; Animals; Female; Macaca; Pyridines; Reverse Transcriptase Inhibitors;

2014
A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Alphapapillomavirus; Anal Canal; Animals; Anti-Infective Agents; Caco-2 Cells; Carrageenan; Female;

2014
A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Carrageenan; Chemistry, Pharmaceutical; Fema

2014
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:7

    Topics: Administration, Intravaginal; Animals; Antiviral Agents; Cervix Uteri; Female; HIV Reverse Transcrip

2015
Multipurpose Prevention Approaches with Antiretroviral-Based Formulations.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:2

    Topics: Administration, Intravaginal; Animals; Anti-Retroviral Agents; Carrageenan; Drug Combinations; Femal

2016
An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques.
    PloS one, 2011, Jan-05, Volume: 6, Issue:1

    Topics: Administration, Intravaginal; Animals; Anti-Retroviral Agents; Drug Combinations; Female; Gels; HIV

2011
The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques.
    Journal of virology, 2011, Volume: 85, Issue:11

    Topics: Administration, Rectal; Animals; Anti-Infective Agents, Local; B-Lymphocytes; Carrageenan; Gels; Mac

2011
A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:11

    Topics: Administration, Intravaginal; Administration, Rectal; Animals; Anti-Infective Agents; Female; Herpes

2012
The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT Infection.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:11

    Topics: Administration, Intravaginal; Administration, Rectal; Animals; Carrageenan; Enzyme Inhibitors; Femal

2012
An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques.
    Science translational medicine, 2012, Sep-05, Volume: 4, Issue:150

    Topics: Administration, Intravaginal; Animals; Contraceptive Devices, Female; Female; Inhibitory Concentrati

2012