uracil has been researched along with Vomiting in 22 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
Excerpt | Relevance | Reference |
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"Although combination chemotherapy with trifluridine/tipiracil (TAS-102) and bevacizumab (BEV) is highly effective for metastatic unresectable colorectal cancer (mCRC), this combination chemotherapy often induces nausea and vomiting." | 8.31 | Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy. ( Fujii, H; Hirose, C; Iihara, H; Kiyama, S; Kobayashi, R; Makiyama, A; Matsuhashi, N; Matsuoka, S; Ohata, K; Sadaka, S; Suzuki, A; Takahashi, T; Watanabe, D, 2023) |
" In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 7.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
"The purpose of this study was to evaluate the efficacy, assessed as response rate, and toxicity of UFT (Tegafur-Uracil) in combination with oxaliplatin as first-line treatment of advanced colorectal cancer (CRC)." | 5.11 | Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer. ( Antón-Aparicio, L; Aparicio, J; Constela, M; Dorta, FJ; Feliu, J; Fonseca, E; García-Girón, C; Gonzalez-Baron, M; Lomas, M; Vicent, JM, 2004) |
"Although combination chemotherapy with trifluridine/tipiracil (TAS-102) and bevacizumab (BEV) is highly effective for metastatic unresectable colorectal cancer (mCRC), this combination chemotherapy often induces nausea and vomiting." | 4.31 | Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy. ( Fujii, H; Hirose, C; Iihara, H; Kiyama, S; Kobayashi, R; Makiyama, A; Matsuhashi, N; Matsuoka, S; Ohata, K; Sadaka, S; Suzuki, A; Takahashi, T; Watanabe, D, 2023) |
" In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 3.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
"Forty-eight patients with unresectable gastric cancer were enrolled for a randomized trial of FP (n = 24) vs FEP (n = 24) combination chemotherapy with respect to their effects on survival period." | 2.68 | [Combination chemotherapy with FP versus FEP in patients with advanced gastric cancer. Research group of gastric cancer chemotherapy]. ( Horiuchi, Y; Ina, K; Iwase, H; Kaneko, H; Kuroiwa, A; Kusugami, K; Morise, K; Oka, Y; Shinoda, M; Suga, S, 1995) |
" Intolerance to single dosing was clearly demonstrated, and only the split dosing was advanced to 500 mg/m2/day." | 2.68 | Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil. ( Chan, KK; Groshen, S; Jeffers, S; Leichman, CG; Leichman, L; Muggia, FM; Spicer, D; Wu, X, 1996) |
" Adverse events to TAS-102 monotherapy were observed in 22 out of 23 cases (95." | 1.43 | Safety of an oral anticancer agent (trifluridine/tipiracil combination tablet) in patients with advanced and recurrent colorectal cancer. ( Asano, H; Go, M; Ito, D; Iwai, M; Kimura, M; Teramachi, H; Usami, E; Yoshimura, T, 2016) |
"Despite this preventative treatment, nausea and/or vomiting occurred in over one-third of all the courses." | 1.28 | [Treatment of nausea and vomiting induced by a 24-hour i.v. infusion of cisplatin]. ( Aoki, Y; Horiuchi, Y; Kamikawa, R; Kyokane, K; Miwa, Y; Nagai, H; Ninomiya, E; Noro, T; Suga, S; Yasue, K, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (13.64) | 18.7374 |
1990's | 15 (68.18) | 18.2507 |
2000's | 2 (9.09) | 29.6817 |
2010's | 1 (4.55) | 24.3611 |
2020's | 1 (4.55) | 2.80 |
Authors | Studies |
---|---|
Matsuoka, S | 1 |
Fujii, H | 1 |
Iihara, H | 1 |
Ohata, K | 1 |
Hirose, C | 1 |
Watanabe, D | 1 |
Sadaka, S | 1 |
Kiyama, S | 1 |
Makiyama, A | 1 |
Takahashi, T | 1 |
Kobayashi, R | 1 |
Matsuhashi, N | 1 |
Suzuki, A | 1 |
Kimura, M | 2 |
Go, M | 1 |
Iwai, M | 1 |
Ito, D | 1 |
Asano, H | 1 |
Usami, E | 1 |
Teramachi, H | 1 |
Yoshimura, T | 1 |
VIETTI, TJ | 1 |
BERRY, DH | 1 |
FERNBACH, DJ | 1 |
LUSHER, J | 1 |
SUTOW, WW | 1 |
Feliu, J | 2 |
Vicent, JM | 1 |
García-Girón, C | 1 |
Constela, M | 1 |
Fonseca, E | 1 |
Aparicio, J | 1 |
Lomas, M | 1 |
Antón-Aparicio, L | 1 |
Dorta, FJ | 1 |
Gonzalez-Baron, M | 1 |
Brussel, W | 1 |
van Kuilenburg, AB | 1 |
Janssens, PM | 1 |
Sato, A | 1 |
Hasegawa, K | 2 |
Kurihara, M | 2 |
Takahashi, M | 1 |
Akazawa, S | 1 |
Fukuyama, Y | 1 |
Koizumi, W | 1 |
Hayakawa, M | 1 |
Sasai, T | 1 |
Kimura, K | 1 |
Sanchiz, F | 1 |
Milla, A | 1 |
Shinoda, M | 1 |
Morise, K | 1 |
Kusugami, K | 2 |
Iwase, H | 2 |
Ina, K | 1 |
Kaneko, H | 1 |
Horiuchi, Y | 2 |
Kuroiwa, A | 1 |
Suga, S | 3 |
Oka, Y | 1 |
Daniels, M | 1 |
Díaz-Rubio, E | 1 |
Guillem, V | 1 |
Montero, JM | 1 |
García-Conde, J | 1 |
Estapé, J | 1 |
Martín, M | 1 |
Herranz, C | 1 |
Ordoñez, A | 1 |
Galán, A | 1 |
Shimada, M | 1 |
Nishio, Y | 1 |
Ichihara, T | 1 |
Ichihara, S | 1 |
Saito, H | 1 |
González Barón, M | 1 |
Espinosa, E | 1 |
García Girón, C | 1 |
de la Gándara, I | 1 |
Espinosa, J | 1 |
Colmenarejo, A | 1 |
Jalón, JI | 1 |
Fernández, Y | 1 |
de Castro, J | 1 |
Kurokawa, H | 1 |
Miura, K | 1 |
Yamashita, Y | 1 |
Tokudome, S | 1 |
Murata, T | 1 |
Kajiyama, M | 1 |
Ichinose, Y | 1 |
Yano, T | 1 |
Kudoh, S | 1 |
Yoshimori, K | 1 |
Morikawa, T | 1 |
Kuba, M | 1 |
Niitani, H | 2 |
Horikoshi, N | 1 |
Aiba, K | 1 |
Kanamaru, R | 1 |
Takeda, S | 1 |
Taguchi, T | 1 |
Furue, H | 1 |
Ogawa, M | 1 |
Abe, T | 1 |
Muggia, FM | 1 |
Wu, X | 1 |
Spicer, D | 1 |
Groshen, S | 1 |
Jeffers, S | 1 |
Leichman, CG | 1 |
Leichman, L | 1 |
Chan, KK | 1 |
DeMario, MD | 1 |
Ratain, MJ | 1 |
Vogelzang, NJ | 1 |
Mani, S | 1 |
Vokes, EE | 1 |
Fleming, GF | 1 |
Melton, K | 1 |
Johnson, S | 1 |
Benner, S | 1 |
Lebwohl, D | 1 |
Sakata, Y | 1 |
Chiba, Y | 1 |
Sato, T | 1 |
Fukushi, G | 1 |
Matsukawa, M | 1 |
Wada, K | 1 |
Aoyama, H | 1 |
Sawada, Y | 1 |
Fukushi, M | 1 |
Ohyama, M | 1 |
Matsumura, M | 1 |
Katsuta, K | 1 |
Nobori, T | 1 |
Matsuyama, H | 1 |
Fukami, K | 1 |
Kiyota, R | 1 |
Yano, H | 1 |
Shima, T | 1 |
Ogawa, K | 1 |
Nagai, H | 1 |
Kyokane, K | 1 |
Miwa, Y | 1 |
Aoki, Y | 1 |
Yasue, K | 1 |
Noro, T | 1 |
Kamikawa, R | 1 |
Ninomiya, E | 1 |
Kikuchi, K | 1 |
Wakui, A | 1 |
Niijima, T | 1 |
Aso, Y | 1 |
Akaza, H | 1 |
Kameyama, S | 1 |
Koiso, K | 1 |
Kawabe, K | 1 |
Kawamura, T | 1 |
Isurugi, K | 1 |
Yokoyama, M | 1 |
Shoji, F | 1 |
13 trials available for uracil and Vomiting
Article | Year |
---|---|
Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Drug Ad | 2004 |
[Combination chemotherapy with tegafur-uracil (UFT) and cisplatin (CDDP) for advanced gastric cancer. UFTP Study Group].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug A | 1995 |
Tegafur-uracil (UFT) plus folinic acid in advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; L | 1994 |
[Combination chemotherapy with FP versus FEP in patients with advanced gastric cancer. Research group of gastric cancer chemotherapy].
Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Admi | 1995 |
Phase II trial of UFT activity in pretreated breast cancer patients.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; A | 1993 |
Neoadjuvant chemotherapy in scirrhous cancer of the stomach using uracil and tegafur and cisplatin.
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy | 1996 |
[Evaluation of neo-adjuvant chemotherapy for oral squamous cell carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 1997 |
UFT plus cisplatin in advanced non-small-cell lung cancer: interim analysis of 67 patients.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cispla | 1997 |
[Phase I study of orally administered UFT plus l-leucovorin].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protoc | 1998 |
Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Cohor | 1996 |
A phase I study of oral uracil/ftorafur (UFT) plus leucovorin and bis-acetato-ammine-dichloro-cyclohexylamine-platinum IV (JM-216) each given over 14 days every 28 days.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1999 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
[Cooperative research of UFT E phase II study. Cooperative Study Group of UFT E in Tohoku Area].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1990 |
9 other studies available for uracil and Vomiting
Article | Year |
---|---|
Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms | 2023 |
Safety of an oral anticancer agent (trifluridine/tipiracil combination tablet) in patients with advanced and recurrent colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Combinations; Female; | 2016 |
URACIL MUSTARY THERAPY IN METASTATIC WILMS'S TUMOR.
Topics: Anemia; Child; Drug Therapy; Leukopenia; Nausea; Neoplasm Metastasis; Nitrogen Mustard Compounds; Th | 1964 |
A neonate with recurrent vomiting and generalized hypotonia diagnosed with a deficiency of dihydropyrimidine dehydrogenase.
Topics: Developmental Disabilities; Dihydrouracil Dehydrogenase (NADP); Female; Homozygote; Humans; Infant; | 2006 |
[UFT].
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combina | 1984 |
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.
Topics: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care; Antidotes; Antimetabolites, Antineop | 1997 |
[A comparative study of UFT enteric-coated granules with UFT capsules on the occurrence of side effects in patients with head and neck cancers--a special attention to the upper gastrointestinal tract disorders].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capsules; Diarrhea; | 1990 |
[Treatment of nausea and vomiting induced by a 24-hour i.v. infusion of cisplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Drug Therapy, Combination; | 1990 |
[Collaborative study of UFT in far-advanced renal cell carcinoma. Urological Cooperative UFT Study Group].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Drug A | 1988 |