uracil has been researched along with Vomiting in 22 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although combination chemotherapy with trifluridine/tipiracil (TAS-102) and bevacizumab (BEV) is highly effective for metastatic unresectable colorectal cancer (mCRC), this combination chemotherapy often induces nausea and vomiting." | 8.31 | Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy. ( Fujii, H; Hirose, C; Iihara, H; Kiyama, S; Kobayashi, R; Makiyama, A; Matsuhashi, N; Matsuoka, S; Ohata, K; Sadaka, S; Suzuki, A; Takahashi, T; Watanabe, D, 2023) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 7.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| "The purpose of this study was to evaluate the efficacy, assessed as response rate, and toxicity of UFT (Tegafur-Uracil) in combination with oxaliplatin as first-line treatment of advanced colorectal cancer (CRC)." | 5.11 | Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer. ( Antón-Aparicio, L; Aparicio, J; Constela, M; Dorta, FJ; Feliu, J; Fonseca, E; García-Girón, C; Gonzalez-Baron, M; Lomas, M; Vicent, JM, 2004) |
| "Although combination chemotherapy with trifluridine/tipiracil (TAS-102) and bevacizumab (BEV) is highly effective for metastatic unresectable colorectal cancer (mCRC), this combination chemotherapy often induces nausea and vomiting." | 4.31 | Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy. ( Fujii, H; Hirose, C; Iihara, H; Kiyama, S; Kobayashi, R; Makiyama, A; Matsuhashi, N; Matsuoka, S; Ohata, K; Sadaka, S; Suzuki, A; Takahashi, T; Watanabe, D, 2023) |
| " In a previous study, the authors demonstrated that the combination of uracil and tegafur (UFT) with leucovorin (LV) was active and well tolerated in patients with advanced colorectal carcinoma (ACC)." | 3.69 | Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group. ( Colmenarejo, A; de Castro, J; de la Gándara, I; Espinosa, E; Espinosa, J; Feliu, J; Fernández, Y; García Girón, C; González Barón, M; Jalón, JI, 1997) |
| "Forty-eight patients with unresectable gastric cancer were enrolled for a randomized trial of FP (n = 24) vs FEP (n = 24) combination chemotherapy with respect to their effects on survival period." | 2.68 | [Combination chemotherapy with FP versus FEP in patients with advanced gastric cancer. Research group of gastric cancer chemotherapy]. ( Horiuchi, Y; Ina, K; Iwase, H; Kaneko, H; Kuroiwa, A; Kusugami, K; Morise, K; Oka, Y; Shinoda, M; Suga, S, 1995) |
| " Intolerance to single dosing was clearly demonstrated, and only the split dosing was advanced to 500 mg/m2/day." | 2.68 | Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil. ( Chan, KK; Groshen, S; Jeffers, S; Leichman, CG; Leichman, L; Muggia, FM; Spicer, D; Wu, X, 1996) |
| " Adverse events to TAS-102 monotherapy were observed in 22 out of 23 cases (95." | 1.43 | Safety of an oral anticancer agent (trifluridine/tipiracil combination tablet) in patients with advanced and recurrent colorectal cancer. ( Asano, H; Go, M; Ito, D; Iwai, M; Kimura, M; Teramachi, H; Usami, E; Yoshimura, T, 2016) |
| "Despite this preventative treatment, nausea and/or vomiting occurred in over one-third of all the courses." | 1.28 | [Treatment of nausea and vomiting induced by a 24-hour i.v. infusion of cisplatin]. ( Aoki, Y; Horiuchi, Y; Kamikawa, R; Kyokane, K; Miwa, Y; Nagai, H; Ninomiya, E; Noro, T; Suga, S; Yasue, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 15 (68.18) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuoka, S | 1 |
| Fujii, H | 1 |
| Iihara, H | 1 |
| Ohata, K | 1 |
| Hirose, C | 1 |
| Watanabe, D | 1 |
| Sadaka, S | 1 |
| Kiyama, S | 1 |
| Makiyama, A | 1 |
| Takahashi, T | 1 |
| Kobayashi, R | 1 |
| Matsuhashi, N | 1 |
| Suzuki, A | 1 |
| Kimura, M | 2 |
| Go, M | 1 |
| Iwai, M | 1 |
| Ito, D | 1 |
| Asano, H | 1 |
| Usami, E | 1 |
| Teramachi, H | 1 |
| Yoshimura, T | 1 |
| VIETTI, TJ | 1 |
| BERRY, DH | 1 |
| FERNBACH, DJ | 1 |
| LUSHER, J | 1 |
| SUTOW, WW | 1 |
| Feliu, J | 2 |
| Vicent, JM | 1 |
| García-Girón, C | 1 |
| Constela, M | 1 |
| Fonseca, E | 1 |
| Aparicio, J | 1 |
| Lomas, M | 1 |
| Antón-Aparicio, L | 1 |
| Dorta, FJ | 1 |
| Gonzalez-Baron, M | 1 |
| Brussel, W | 1 |
| van Kuilenburg, AB | 1 |
| Janssens, PM | 1 |
| Sato, A | 1 |
| Hasegawa, K | 2 |
| Kurihara, M | 2 |
| Takahashi, M | 1 |
| Akazawa, S | 1 |
| Fukuyama, Y | 1 |
| Koizumi, W | 1 |
| Hayakawa, M | 1 |
| Sasai, T | 1 |
| Kimura, K | 1 |
| Sanchiz, F | 1 |
| Milla, A | 1 |
| Shinoda, M | 1 |
| Morise, K | 1 |
| Kusugami, K | 2 |
| Iwase, H | 2 |
| Ina, K | 1 |
| Kaneko, H | 1 |
| Horiuchi, Y | 2 |
| Kuroiwa, A | 1 |
| Suga, S | 3 |
| Oka, Y | 1 |
| Daniels, M | 1 |
| Díaz-Rubio, E | 1 |
| Guillem, V | 1 |
| Montero, JM | 1 |
| García-Conde, J | 1 |
| Estapé, J | 1 |
| Martín, M | 1 |
| Herranz, C | 1 |
| Ordoñez, A | 1 |
| Galán, A | 1 |
| Shimada, M | 1 |
| Nishio, Y | 1 |
| Ichihara, T | 1 |
| Ichihara, S | 1 |
| Saito, H | 1 |
| González Barón, M | 1 |
| Espinosa, E | 1 |
| García Girón, C | 1 |
| de la Gándara, I | 1 |
| Espinosa, J | 1 |
| Colmenarejo, A | 1 |
| Jalón, JI | 1 |
| Fernández, Y | 1 |
| de Castro, J | 1 |
| Kurokawa, H | 1 |
| Miura, K | 1 |
| Yamashita, Y | 1 |
| Tokudome, S | 1 |
| Murata, T | 1 |
| Kajiyama, M | 1 |
| Ichinose, Y | 1 |
| Yano, T | 1 |
| Kudoh, S | 1 |
| Yoshimori, K | 1 |
| Morikawa, T | 1 |
| Kuba, M | 1 |
| Niitani, H | 2 |
| Horikoshi, N | 1 |
| Aiba, K | 1 |
| Kanamaru, R | 1 |
| Takeda, S | 1 |
| Taguchi, T | 1 |
| Furue, H | 1 |
| Ogawa, M | 1 |
| Abe, T | 1 |
| Muggia, FM | 1 |
| Wu, X | 1 |
| Spicer, D | 1 |
| Groshen, S | 1 |
| Jeffers, S | 1 |
| Leichman, CG | 1 |
| Leichman, L | 1 |
| Chan, KK | 1 |
| DeMario, MD | 1 |
| Ratain, MJ | 1 |
| Vogelzang, NJ | 1 |
| Mani, S | 1 |
| Vokes, EE | 1 |
| Fleming, GF | 1 |
| Melton, K | 1 |
| Johnson, S | 1 |
| Benner, S | 1 |
| Lebwohl, D | 1 |
| Sakata, Y | 1 |
| Chiba, Y | 1 |
| Sato, T | 1 |
| Fukushi, G | 1 |
| Matsukawa, M | 1 |
| Wada, K | 1 |
| Aoyama, H | 1 |
| Sawada, Y | 1 |
| Fukushi, M | 1 |
| Ohyama, M | 1 |
| Matsumura, M | 1 |
| Katsuta, K | 1 |
| Nobori, T | 1 |
| Matsuyama, H | 1 |
| Fukami, K | 1 |
| Kiyota, R | 1 |
| Yano, H | 1 |
| Shima, T | 1 |
| Ogawa, K | 1 |
| Nagai, H | 1 |
| Kyokane, K | 1 |
| Miwa, Y | 1 |
| Aoki, Y | 1 |
| Yasue, K | 1 |
| Noro, T | 1 |
| Kamikawa, R | 1 |
| Ninomiya, E | 1 |
| Kikuchi, K | 1 |
| Wakui, A | 1 |
| Niijima, T | 1 |
| Aso, Y | 1 |
| Akaza, H | 1 |
| Kameyama, S | 1 |
| Koiso, K | 1 |
| Kawabe, K | 1 |
| Kawamura, T | 1 |
| Isurugi, K | 1 |
| Yokoyama, M | 1 |
| Shoji, F | 1 |
13 trials available for uracil and Vomiting
| Article | Year |
|---|---|
Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea; Drug Ad | 2004 |
[Combination chemotherapy with tegafur-uracil (UFT) and cisplatin (CDDP) for advanced gastric cancer. UFTP Study Group].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug A | 1995 |
Tegafur-uracil (UFT) plus folinic acid in advanced rectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; L | 1994 |
[Combination chemotherapy with FP versus FEP in patients with advanced gastric cancer. Research group of gastric cancer chemotherapy].
Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Admi | 1995 |
Phase II trial of UFT activity in pretreated breast cancer patients.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; A | 1993 |
Neoadjuvant chemotherapy in scirrhous cancer of the stomach using uracil and tegafur and cisplatin.
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy | 1996 |
[Evaluation of neo-adjuvant chemotherapy for oral squamous cell carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 1997 |
UFT plus cisplatin in advanced non-small-cell lung cancer: interim analysis of 67 patients.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cispla | 1997 |
[Phase I study of orally administered UFT plus l-leucovorin].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protoc | 1998 |
Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Cohor | 1996 |
A phase I study of oral uracil/ftorafur (UFT) plus leucovorin and bis-acetato-ammine-dichloro-cyclohexylamine-platinum IV (JM-216) each given over 14 days every 28 days.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1999 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
[Cooperative research of UFT E phase II study. Cooperative Study Group of UFT E in Tohoku Area].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 1990 |
9 other studies available for uracil and Vomiting
| Article | Year |
|---|---|
Emetogenicity and Risk Factors of Nausea and Vomiting in Patients With Metastatic Colorectal Cancer Receiving Trifluridine/Tipiracil and Bevacizumab Chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms | 2023 |
Safety of an oral anticancer agent (trifluridine/tipiracil combination tablet) in patients with advanced and recurrent colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Drug Combinations; Female; | 2016 |
URACIL MUSTARY THERAPY IN METASTATIC WILMS'S TUMOR.
Topics: Anemia; Child; Drug Therapy; Leukopenia; Nausea; Neoplasm Metastasis; Nitrogen Mustard Compounds; Th | 1964 |
A neonate with recurrent vomiting and generalized hypotonia diagnosed with a deficiency of dihydropyrimidine dehydrogenase.
Topics: Developmental Disabilities; Dihydrouracil Dehydrogenase (NADP); Female; Homozygote; Humans; Infant; | 2006 |
[UFT].
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combina | 1984 |
Uracil and tegafur modulated with leucovorin: an effective regimen with low toxicity for the treatment of colorectal carcinoma in the elderly. Oncopaz Cooperative Group.
Topics: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care; Antidotes; Antimetabolites, Antineop | 1997 |
[A comparative study of UFT enteric-coated granules with UFT capsules on the occurrence of side effects in patients with head and neck cancers--a special attention to the upper gastrointestinal tract disorders].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capsules; Diarrhea; | 1990 |
[Treatment of nausea and vomiting induced by a 24-hour i.v. infusion of cisplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Drug Therapy, Combination; | 1990 |
[Collaborative study of UFT in far-advanced renal cell carcinoma. Urological Cooperative UFT Study Group].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Drug A | 1988 |