uracil and Sarcoma 180
uracil has been researched along with Sarcoma 180 in 26 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Sarcoma 180: An experimental sarcoma of mice.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combinations of 6-thioguanine and uracil mustard produced greater inhibition of the growth of sarcoma 180 than that equivalent to the sum of the inhibitory effects caused by the optimum levels of the individual drugs." | 7.64 | Sarcoma 180 inhibition by combinations of 6-thioguanine and uracil mustard. ( BOOTH, BA; SARTORELLI, AC, 1962) |
| "Combinations of 6-thioguanine and uracil mustard produced greater inhibition of the growth of sarcoma 180 than that equivalent to the sum of the inhibitory effects caused by the optimum levels of the individual drugs." | 3.64 | Sarcoma 180 inhibition by combinations of 6-thioguanine and uracil mustard. ( BOOTH, BA; SARTORELLI, AC, 1962) |
Research
Studies (26)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (88.46) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| EVANS, JS | 1 |
| MENGEL, GD | 1 |
| ANIGSTEIN, L | 1 |
| ANIGSTEIN, DM | 1 |
| RENNELS, EG | 1 |
| BOOTH, BA | 1 |
| SARTORELLI, AC | 1 |
| ADAMS, DH | 1 |
| STANISLAVSKAIA, MS | 1 |
| AKSAMITNAIA, Ia | 1 |
| SATO, K | 1 |
| LEPAGE, GA | 1 |
| Watson, JD | 1 |
| Ralph, RK | 1 |
| Nakamura, H | 2 |
| Yu-Qin, W | 1 |
| Miyauchi, S | 1 |
| Nishioka, N | 1 |
| Tanaka, H | 1 |
| Harada, N | 1 |
| Shirasaka, T | 5 |
| Fujii, S | 6 |
| Kitano, S | 2 |
| Ikenaka, K | 3 |
| Fukushima, M | 4 |
| Maehara, Y | 1 |
| Kanazawa, Y | 1 |
| Kurogi, S | 1 |
| Shinohara, S | 1 |
| Noda, Y | 1 |
| Masuda, K | 1 |
| Hattori, H | 1 |
| Nozawa, E | 1 |
| Iino, T | 1 |
| Yoshimura, Y | 1 |
| Shuto, S | 1 |
| Shimamoto, Y | 1 |
| Nomura, M | 1 |
| Tanaka, M | 1 |
| Sasaki, T | 1 |
| Matsuda, A | 1 |
| Chowdhury, K | 1 |
| Neogy, RK | 1 |
| Singh, UP | 1 |
| Singh, BN | 1 |
| Ghose, AK | 1 |
| Singh, RK | 1 |
| Sodhi, A | 1 |
| Miwa, M | 1 |
| Eda, H | 1 |
| Fukuda, H | 1 |
| Fujimoto, K | 1 |
| Ishitsuka, H | 1 |
| Tatsumi, K | 1 |
| Aoike, A | 1 |
| Hosokawa, T | 1 |
| Koyama, K | 1 |
| Rokutan, K | 1 |
| Nishi, Y | 1 |
| Yoshida, A | 1 |
| Nakamura, K | 1 |
| Kawai, K | 1 |
| Severin, E | 1 |
| Hagenhoff, B | 1 |
| Lin, TS | 1 |
| Liu, MC | 1 |
| Gerns, FR | 1 |
| Perrotta, A | 1 |
| Hitchings, GH | 1 |
| Terent'eva, TG | 1 |
| Fomina, IP | 1 |
| Navashin, SM | 1 |
| Pol'kina, RI | 1 |
| Giner-Sorolla, A | 1 |
| Medrek, L | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449] | Phase 3 | 338 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
26 other studies available for uracil and Sarcoma 180
| Article | Year |
|---|---|
Antitumor activity of 5-bis(2-chloroethyl) amino uracil against sarcoma 180 and Ehrlich carcinoma.
Topics: Animals; Carcinoma; Mechlorethamine; Nitrogen Mustard Compounds; Sarcoma 180; Uracil | 1958 |
Growth inhibition of sarcoma 180 by hormone antisera and 5-fluor-ouracil.
Topics: Animals; Fluorouracil; Growth Hormone; Human Growth Hormone; Humans; Immune Sera; Sarcoma 180; Uraci | 1963 |
Sarcoma 180 inhibition by combinations of 6-thioguanine and uracil mustard.
Topics: Animals; Antineoplastic Agents; Mercaptopurine; Sarcoma 180; Thioguanine; Uracil; Uracil Mustard | 1962 |
THE UPTAKE OF FUANINE, URACIL, LYSINE AND GLYCINE BY ASCITES CELLS PRETREATED WITH AZASERINE AND 6-THIOGUANINE.
Topics: Animals; Antineoplastic Agents; Ascites; Azaserine; Carbon Isotopes; DNA; DNA, Neoplasm; Glycine; Gu | 1963 |
[EXPERIMENTAL STUDIES ON THE ANTINEOPLASTIC EFFECT OF OLIVOMYCIN IN ASSOCIATION WITH SOME SYNTHETIC CYTOSTATIC DRUGS IN CROCKER'S SARCOMA].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Busulfan; Cytost | 1963 |
[EFFECT OF SOME PYRIMIDINE DERIVATIVES ON THE GROWTH OF CROCKER'S SARCOMA].
Topics: Animals; Antineoplastic Agents; Cytosine; Mice; Neoplasms; Pharmacology; Pyrimidines; Research; Sarc | 1963 |
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neopla | 1965 |
DNA-associated RNA from sarcoma 180 cells.
Topics: Adenine; Animals; Cytosine; Dactinomycin; DNA, Neoplasm; Guanine; Kinetics; Mice; Nucleotidyltransfe | 1967 |
[Studies on the mechanism of antitumor activity of 5-FU and its derivatives--relationship between the inhibition of tumor growth and the inhibition of thymidylate synthetase in vivo].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; DNA, | 1984 |
Effect of coadministration of thymine or thymidine on the antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biodegradation, Environmental; Drug Synergism; | 1980 |
In vivo 19F NMR comparative study of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil (FT) and an FT-uracil coadministration system in mouse tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorine; Fluorouracil; Liver; Magnetic Res | 1994 |
Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.
Topics: Animals; Antimetabolites, Antineoplastic; Carbohydrate Sequence; Cell Division; Cytosine; Drug Scree | 1998 |
Effect of coadministration of uracil or cytosine on the anti-tumor activity of clinical doses of 1-(2-tetrahydrofuryl)-5-fluorouracil and level of 5-fluorouracil in rodents.
Topics: Administration, Oral; Animals; Cytosine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Li | 1979 |
Effect of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil.
Topics: Animals; Drug Therapy, Combination; Fluorouracil; Liver Neoplasms, Experimental; Male; Mice; Rats; S | 1978 |
Mode of action of Withaferin A and Withanolide D.
Topics: Animals; Antineoplastic Agents; Cholestenes; Cholestenones; Depression, Chemical; Ethers, Cyclic; La | 1975 |
Synthesis, characterization, and antitumor activity of 5-iodouracil complexes.
Topics: Animals; Antineoplastic Agents; Cadmium; Cobalt; Copper; Electron Spin Resonance Spectroscopy; Femal | 1991 |
[BOF-A1 and BOF-A2, new 5-FU degradation-inhibitory agents].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Fluorou | 1987 |
[Comparative studies on the antitumor activity of the fluorinated pyrimidines 5'-DFUR, tegafur, UFT and FUra on various murine tumors].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Floxuridine; Fluorouraci | 1988 |
Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts.
Topics: Animals; Barbiturates; Chromatography, High Pressure Liquid; Dihydrouracil Dehydrogenase (NAD+); Flu | 1987 |
[Effect of fluoropyrimidine, drugs of tegafur and UFT on transplanted tumor in liver-damaged mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Tetrachloride Poisoning; Chemical an | 1988 |
[Synchronization of tumor cells with 5-fluorouracil plus uracil and with vinblastine and irradiation of the synchronized cultures. A contribution to combined radio-chemotherapy].
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Combined Modality Therapy; Fluorouracil; In Vitro | 1988 |
Synthesis of 1-[[2-hydroxy-1-(hydroxymethyl)ethoxy] methyl]-5-benzyluracil and its amino analogue, new potent uridine phosphorylase inhibitors with high water solubility.
Topics: Animals; Chemical Phenomena; Chemistry; Mice; Pentosyltransferases; Sarcoma 180; Solubility; Uracil; | 1985 |
5-Arylaminopyrimidines.
Topics: Animals; Antimetabolites; Chemistry, Organic; Enterobacter; Enterococcus faecalis; Escherichia coli; | 1966 |
[Experimental study of the antineoplastic effect of the antibiotic polymycin].
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antifungal Agents; Antiviral Agents; As | 1970 |
[Effect of 4-methyluracil on the antineoplastic and toxic effect of 6-mercaptopurine].
Topics: Animals; Drug Synergism; Lymphoma, Non-Hodgkin; Mercaptopurine; Mice; Neoplasm Transplantation; Neop | 1971 |
Synthesis and properties of 5-mercaptomethyluracil and related derivatives.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, Krebs 2; Chemistry, Organic; Mi | 1966 |