uracil and Prediabetes
uracil has been researched along with Prediabetes in 6 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study was to evaluate whether dipeptidyl peptidase-4 (DPP-4) inhibitor alogliptin (ALO) alone or in combination with pioglitazone (PIO) improves β-cell function along with insulin resistance (IR) in metformin (MET) treated obese women with PCOS with persistent IR." | 9.24 | Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS. ( Goricar, K; Janez, A; Jensterle, M, 2017) |
| " The aim of the study was to evaluate whether dipeptidyl peptidase-4 (DPP-4) inhibitor alogliptin (ALO) alone or in combination with pioglitazone (PIO) improves β-cell function along with insulin resistance (IR) in metformin (MET) treated obese women with PCOS with persistent IR." | 5.24 | Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS. ( Goricar, K; Janez, A; Jensterle, M, 2017) |
| " The moderate hyperglycaemia seen in prediabetes can be treated using a combination of metformin and lifestyle interventions (low-calorie diets and exercising)." | 4.12 | Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats. ( Akinnuga, AM; Booysen, IN; Ismail, MB; Khathi, A; Khumalo, B; Ngubane, P; Sibiya, NH; Siboto, A, 2022) |
| "Alogliptin is a potent and highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor." | 1.37 | Effects of chronic administration of alogliptin on the development of diabetes and β-cell function in high fat diet/streptozotocin diabetic mice. ( Huang, Y; Wang, J; Wang, Z; Zhang, X, 2011) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Siboto, A | 2 |
| Akinnuga, AM | 2 |
| Khumalo, B | 2 |
| Ismail, MB | 2 |
| Booysen, IN | 3 |
| Sibiya, NH | 2 |
| Ngubane, P | 2 |
| Khathi, A | 3 |
| Mabuza, LP | 1 |
| Gamede, MW | 1 |
| Maikoo, S | 1 |
| Ngubane, PS | 1 |
| Jensterle, M | 1 |
| Goricar, K | 1 |
| Janez, A | 1 |
| Cai, Y | 1 |
| Lydic, TA | 1 |
| Turkette, T | 1 |
| Reid, GE | 1 |
| Olson, LK | 1 |
| Moritoh, Y | 1 |
| Takeuchi, K | 1 |
| Hazama, M | 1 |
| Zhang, X | 1 |
| Wang, Z | 1 |
| Huang, Y | 1 |
| Wang, J | 1 |
Trials
1 trial available for uracil and Prediabetes
| Article | Year |
|---|---|
Add on DPP-4 inhibitor alogliptin alone or in combination with pioglitazone improved β-cell function and insulin sensitivity in metformin treated PCOS.
Topics: Adult; Body Mass Index; Cohort Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitor | 2017 |
Other Studies
5 other studies available for uracil and Prediabetes
| Article | Year |
|---|---|
Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diet; Glomerular Filtration Rate; Hyperglycemia; Kidney; Kidney | 2022 |
Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diet; Glomerular Filtration Rate; Hyperglycemia; Kidney; Kidney | 2022 |
Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diet; Glomerular Filtration Rate; Hyperglycemia; Kidney; Kidney | 2022 |
Ameliorative Effects of a Rhenium (V) Compound with Uracil-Derived Ligand Markers Associated with Hyperglycaemia-Induced Renal Dysfunction in Diet-Induced Prediabetic Rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diet; Glomerular Filtration Rate; Hyperglycemia; Kidney; Kidney | 2022 |
Amelioration of risk factors associated with diabetic nephropathy in diet-induced pre-diabetic rats by an uracil-derived diimine ruthenium(II) compound.
Topics: Albuminuria; Aldosterone; Animals; Biomarkers; Cell Adhesion Molecules; Creatinine; Diabetic Nephrop | 2020 |
Impact of alogliptin and pioglitazone on lipid metabolism in islets of prediabetic and diabetic Zucker Diabetic Fatty rats.
Topics: Animals; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Islets of Langerhans; Lipid Metabolis | 2015 |
Combination treatment with alogliptin and voglibose increases active GLP-1 circulation, prevents the development of diabetes and preserves pancreatic beta-cells in prediabetic db/db mice.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Hypoglycemic Agents; Inositol; | 2010 |
Effects of chronic administration of alogliptin on the development of diabetes and β-cell function in high fat diet/streptozotocin diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Dose-Res | 2011 |