Page last updated: 2024-10-20

uracil and Peritoneal Carcinomatosis

uracil has been researched along with Peritoneal Carcinomatosis in 26 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
"The aim was to determine the recommended dose of combined chemotherapy with mitoxantrone and uracil/tegafur (Phase I part) and to clarify its efficacy and safety in patients with advanced hepatocellular carcinoma at the recommended dose (Phase II part)."9.15A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma. ( Furuse, J; Ikeda, M; Ishii, H; Mitsunaga, S; Morizane, C; Nakachi, K; Okusaka, T; Suzuki, E; Ueno, H, 2011)
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination."5.511-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019)
"The aim was to determine the recommended dose of combined chemotherapy with mitoxantrone and uracil/tegafur (Phase I part) and to clarify its efficacy and safety in patients with advanced hepatocellular carcinoma at the recommended dose (Phase II part)."5.15A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma. ( Furuse, J; Ikeda, M; Ishii, H; Mitsunaga, S; Morizane, C; Nakachi, K; Okusaka, T; Suzuki, E; Ueno, H, 2011)
"More than two-thirds of patients with gastric cancer present with metastatic disease and their curative options are limited."2.73Phase II study of cisplatin, epirubicin, UFT, and leucovorin (PELUF) as first-line chemotherapy in metastatic gastric cancer. ( Baruch, NB; Biran, H; Dinerman, M; Idelevich, E; Karminsky, N; Katsenelson, RL; Man, S; Shani, A; Zvi, NB, 2007)
"Uracil-tegafur (UFT) has been reported to have a broad anti-tumor activity in a variety of malignancies including colorectal cancer and breast cancer."2.70Phase II study of uracil-tegafur in patients with metastatic pancreatic cancer. ( Ikeda, M; Kuriyama, H; Okada, S; Okusaka, T; Ueno, H, 2002)
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination."1.511-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019)
"However, the role of MCTs in gastric cancer (GC) is not fully understood."1.43MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis. ( Ahn, SM; Chang, WJ; Cho, JH; Jung, KS; Kang, WK; Kim, HS; Kim, KM; Kim, ST; Kim, SY; Lee, I; Lee, J; Lee, JY; Lee, S; Lim, HY; Lim, SH; Park, JO; Park, SH; Park, YS; Song, HN; Yoo, KH, 2016)
"Peritoneal metastasis of breast cancer was suspected, and an operation was performed for a definitive diagnosis."1.42[A Case of Peritoneal Metastasis of Breast Cancer Diagnosed by Laparoscopic-Assisted Right Hemicolectomy]. ( Egawa, C; Goto, T; Hashimoto, T; Ishida, T; Kagawa, Y; Kato, T; Katsura, Y; Kimura, K; Kusama, H; Matsushita, K; Morimoto, Y; Motoyama, Y; Murakami, K; Nagano, T; Naito, A; Nakatsuka, S; Nitta, K; Ohmura, Y; Ohneda, Y; Okishiro, M; Sakisaka, H; Sato, Y; Takatsuka, Y; Takeda, Y; Takeno, A; Tamura, S; Taniguchi, H, 2015)
" We conducted an analysis to evaluate the efficacy and feasibility of modified pharmacokinetic modulating chemotherapy, for gastric cancer patients with peritoneal dissemination."1.33[Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination]. ( Ishikawa, T; Kamimura, T; Mizuno, K; Ohta, H; Seki, K; Togashi, T; Watanabe, K; Yoshida, T, 2005)
"Treatment of advanced gastric cancers with peritonitis carcinomatosa is very difficult, because none of the various therapies (operation, chemotherapy, hyperthermia etc."1.32[A case of advanced gastric cancer with peritonitis carcinomatosa resected with intraperitoneal chemotherapy based on chemosensitivity test with ascites]. ( Doi, K; Horiuchi, T; Nakamura, T; Okubo, Y; Shimada, K; Tanabe, S; Tanaka, K; Tanaka, S; Uchinami, M; Yoshida, M, 2004)
"Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon."1.31Complete disappearance of recurrent hepatocellular carcinoma with peritoneal dissemination and splenic metastasis: a unique clinical course after surgery. ( Amano, J; Hanazaki, K; Koide, N; Matsunaga, Y; Shiohara, E; Terasaki, T, 2000)
"We encountered a case of unresectable colon cancer that disappeared following pharmacokinetic modulating chemotherapy (PMC)."1.31[A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)]. ( Asahara, T; Nakahara, H; Nakahara, M; Okajima, M; Yano, M, 2000)
"We reported a case of gastric cancer with peritoneal dissemination, which was successfully treated by neoadjuvant chemotherapy and partial gastrectomy."1.29[Case report of long-term survivor of advanced gastric cancer associated with peritoneal dissemination successfully treated with cancer chemotherapy]. ( Ikeda, K; Shibata, N; Tamai, M, 1995)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's6 (23.08)18.2507
2000's14 (53.85)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, J1
Yang, X1
Li, X1
Gao, H1
Liu, N1
Guo, X1
Sato, Y1
Okishiro, M1
Ohneda, Y1
Motoyama, Y1
Ishida, T1
Morimoto, Y1
Kusama, H1
Matsushita, K1
Hashimoto, T1
Kimura, K1
Naito, A1
Murakami, K1
Katsura, Y1
Nitta, K1
Ohmura, Y1
Kagawa, Y1
Takeno, A1
Sakisaka, H1
Taniguchi, H1
Egawa, C1
Takeda, Y1
Kato, T1
Tamura, S1
Takatsuka, Y1
Goto, T1
Nagano, T1
Nakatsuka, S1
Lee, JY1
Lee, I1
Chang, WJ1
Ahn, SM1
Lim, SH1
Kim, HS1
Yoo, KH1
Jung, KS1
Song, HN1
Cho, JH1
Kim, SY1
Kim, KM1
Lee, S1
Kim, ST1
Park, SH1
Lee, J1
Park, JO1
Park, YS1
Lim, HY1
Kang, WK1
Suzuki, E1
Furuse, J1
Ikeda, M2
Ishii, H1
Okusaka, T2
Nakachi, K1
Mitsunaga, S1
Ueno, H2
Morizane, C1
Usuki, H1
Ishimura, K1
Yachida, S1
Hagiike, M1
Okano, K1
Izuishi, K1
Karasawa, Y1
Goda, F1
Maeta, H1
Terashima, M1
Fujiwara, H1
Takagane, A1
Abe, K1
Irinoda, T1
Nakaya, T1
Yonezawa, H1
Oyama, K1
Saito, K1
Kanzaki, N1
Ohtani, S1
Nemoto, T1
Hoshino, Y1
Kogure, M1
Gotoh, M1
Nakayama, H1
Aoki, N1
Hayashi, S1
Wakabayashi, K1
Karube, H1
Ogame, H1
Aoki, H1
Sakamoto, N1
Masuda, H1
Hemmi, A1
Nakamura, T1
Shimada, K1
Okubo, Y1
Tanaka, S1
Tanabe, S1
Yoshida, M1
Doi, K1
Uchinami, M1
Horiuchi, T1
Tanaka, K1
Ishikawa, T2
Mizuno, K1
Togashi, T1
Watanabe, K1
Seki, K1
Ohta, H1
Yoshida, T1
Kamimura, T1
Okabayashi, K1
Hasegawa, H1
Kawano, Y1
Kawano, S1
Nishibori, H1
Ishii, Y1
Yamauchi, T1
Kawano, T1
Kitajima, M1
Asai, K1
Fujita, T1
Nakamura, Y1
Tokuda, E1
Hiyoshi, M1
Aoki, F1
Sugizaki, K1
Masaki, Y1
Shibaki, T1
Morimoto, N1
Idelevich, E1
Karminsky, N1
Dinerman, M1
Katsenelson, RL1
Zvi, NB1
Baruch, NB1
Biran, H1
Man, S1
Shani, A1
Shibata, N1
Tamai, M1
Ikeda, K2
Yoshiyuki, T1
Onda, M1
Tokunaga, A1
Teramoto, T1
Oguri, T1
Fujita, I1
Okuda, T1
Mizutani, T1
Kiyama, T1
Shimizu, Y1
Maehara, Y1
Okuyama, T1
Kakeji, Y1
Baba, H1
Furusawa, M1
Sugimachi, K1
Otani, S1
Maeta, M1
Oka, A1
Hirooka, Y1
Tsujitani, S1
Ikeguchi, M1
Hamazoe, R1
Kaibara, N1
Ohtani, M1
Takayama, S1
Ogata, N1
Sekine, C1
Nimura, H1
Tsutsumi, J1
Kashimura, H1
Sano, Y1
Inoue, Y1
Aoki, T1
Ito, H1
Imada, T1
Kondo, J1
Amano, T1
Maehara, T1
Rino, Y1
Takahashi, M1
Shiozawa, M1
Hatori, S1
Suzuki, Y1
Terasaki, T1
Hanazaki, K1
Shiohara, E1
Matsunaga, Y1
Koide, N1
Amano, J1
Nakahara, H1
Okajima, M1
Nakahara, M1
Yano, M1
Asahara, T1
Ogawa, Y1
Ogisawa, K1
Nagatsuka, I1
Matsumura, Y1
Takashima, T1
Yashiro, M1
Onoda, N1
Nakata, B1
Kato, Y1
Hirakawa, K1
Akamo, Y1
Takeyama, H1
Hasegawa, M1
Teranishi, F1
Manabe, T1
Okada, S1
Kuriyama, H1
Hayashi, T1
Nasu, Y1
Aramaki, K1
Johsen, T1
Matsuura, H1
Schmähl, D1

Trials

6 trials available for uracil and Peritoneal Carcinomatosis

ArticleYear
A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:3

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carci

2011
Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2003, Volume: 6 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2003
Phase II study of cisplatin, epirubicin, UFT, and leucovorin (PELUF) as first-line chemotherapy in metastatic gastric cancer.
    Acta oncologica (Stockholm, Sweden), 2007, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplat

2007
[Treatment for peritoneal dissemination of gastric cancer by intraperitoneal administration of CDDP through Infuse-a-Port].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj

1994
Postoperative immunochemotherapy including streptococcal lysate OK-432 is effective for patients with gastric cancer and serosal invasion.
    American journal of surgery, 1994, Volume: 168, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modali

1994
Phase II study of uracil-tegafur in patients with metastatic pancreatic cancer.
    Oncology, 2002, Volume: 62, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Female;

2002

Other Studies

20 other studies available for uracil and Peritoneal Carcinomatosis

ArticleYear
1-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:16

    Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Adhesion; Cell Line, Tumor; Female; Focal Adhesion Kina

2019
[A Case of Peritoneal Metastasis of Breast Cancer Diagnosed by Laparoscopic-Assisted Right Hemicolectomy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemothe

2015
MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; F

2016
Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2003, Volume: 6 Suppl 1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehyd

2003
[A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:2

    Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoembryo

2004
[A case of advanced gastric cancer with peritonitis carcinomatosa resected with intraperitoneal chemotherapy based on chemosensitivity test with ascites].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Ascitic Fluid; Cisplatin; Drug Administrati

2004
[Modified pharmacokinetic modulating chemotherapy for progressive gastric cancer accompanied by peritoneal dissemination].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Angiotensin II; Antineoplastic Combined Chemot

2005
[A case of colorectal cancer effectively treated with UFT/LV].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Mo

2005
[A case of multiple hepatic and peritoneal metastases from colon cancer responding to oral UFT+leucovorin chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Col

2005
[Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc

2006
[Case report of long-term survivor of advanced gastric cancer associated with peritoneal dissemination successfully treated with cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouraci

1995
Long-term survival of 5 years following initial surgery for gastric cancer and simultaneous disseminated peritoneal metastasis: report of a case.
    Surgery today, 1995, Volume: 25, Issue:11

    Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fatal Outcome;

1995
[Usefulness of contrast-enhanced CT of the peritoneum to evaluate efficacy of neoadjuvant chemotherapy for peritoneal dissemination in an advanced gastric cancer case].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Combin

1996
A case of malignant peritoneal mesothelioma showed complete remission with chemotherapy.
    Japanese journal of clinical oncology, 1998, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Combined Modality Therapy

1998
Complete disappearance of recurrent hepatocellular carcinoma with peritoneal dissemination and splenic metastasis: a unique clinical course after surgery.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Thera

2000
[A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:10

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug

2000
[Three cases of metastatic breast cancer, resistant to pre-chemo and/or endocrine therapy, markedly improved with UFT and cyclophosphamide oral combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:13

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplas

2000
[Efficacy of intraperitoneal chemotherapy for peritoneal recurrence of gastric carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administ

2001
[A case of peritoneal malignant mesothelioma with disappearance of ascites result of intraperitoneal instillation of mitomycin C and oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cryptorch

1989
[Examination of 1,3-dimethyl-4-amino-5-nitroso-uracile for carcinogenic effect in rats (author's transl)].
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1973, Dec-28, Volume: 80, Issue:4

    Topics: Animals; Chemical Phenomena; Chemistry; Fibrosarcoma; Injections, Intraperitoneal; Leukemia; Lymphom

1973