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uracil and Papilloma

uracil has been researched along with Papilloma in 15 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Direct mechanical irritation by uracil calculi formed following feeding of 3% uracil in the diet to male rats produces severe papillary hyperplasia (papillomatosis, which is reversible) of bladder epithelium."7.70Expression and localization of ornithine decarboxylase in reversible papillomatosis induced by uracil in rat bladder. ( Fukushima, S; Kitamura, Y; Nomura, S; Otani, S; Otori, K; Takada, N; Yano, Y, 1998)
"Expression of rat urinary bladder cathepsin E in benign papillomatosis induced by uracil and various stages of N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)-induced carcinogenesis was investigated immunohistochemically."7.69Immunohistochemically demonstrated variation in expression of cathepsin E between uracil-induced papillomatosis and N-butyl-N-(4-hydroxybutyl)nitrosamine-induced preneoplastic and neoplastic changes in rat urinary bladder. ( Fukushima, S; Ichinose, M; Inoue, H; Masui, T; Miki, K; Tatematsu, M; Yamamoto, S; Yonezawa, S, 1996)
"In the present study, Tbx3, a member of the T-box family of transcription factors, was identified as an up-regulated gene by mRNA differential display in the regression (apoptosis) stage after uracil-induction of papillomatosis in the rat urinary bladder."3.73Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells. ( Asamoto, M; Hokaiwado, N; Ito, A; Shirai, T; Takahashi, S, 2005)
"Direct mechanical irritation by uracil calculi formed following feeding of 3% uracil in the diet to male rats produces severe papillary hyperplasia (papillomatosis, which is reversible) of bladder epithelium."3.70Expression and localization of ornithine decarboxylase in reversible papillomatosis induced by uracil in rat bladder. ( Fukushima, S; Kitamura, Y; Nomura, S; Otani, S; Otori, K; Takada, N; Yano, Y, 1998)
" In the first study, 3% uracil was fed for 4 weeks to cause urinary calculi and consequent hyperplasia and papillomatosis, both regressing after withdrawal of the insult."3.70Aberrant expression of p27(Kip1) is associated with malignant transformation of the rat urinary bladder epithelium. ( Asamoto, M; Kimoto, N; Nakanishi, M; Ogawa, K; Shirai, T; Takahashi, S, 2000)
"Differences between the reversible papillomatosis and preneoplastic lesions of the urinary bladder of rats were investigated in terms of cell proliferation and apoptosis after cessation of uracil administration."3.69Differences in cell proliferation and apoptosis between reversible and irreversible mucosal lesions associated with uracil-induced urolithiasis in N-butyl-N-(4-hydroxybutyl)nitrosamine-pretreated. ( Hirose, M; Imaida, K; Shibata, M; Shirai, T; Tagawa, Y; Takahashi, S, 1995)
"Expression of rat urinary bladder cathepsin E in benign papillomatosis induced by uracil and various stages of N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)-induced carcinogenesis was investigated immunohistochemically."3.69Immunohistochemically demonstrated variation in expression of cathepsin E between uracil-induced papillomatosis and N-butyl-N-(4-hydroxybutyl)nitrosamine-induced preneoplastic and neoplastic changes in rat urinary bladder. ( Fukushima, S; Ichinose, M; Inoue, H; Masui, T; Miki, K; Tatematsu, M; Yamamoto, S; Yonezawa, S, 1996)
"Five non-genotoxic chemicals previously demonstrated to be bladder cancer promoters in 36-week in vivo assays for carcinogenesis were reevaluated in a 20-week experiment in order to assess the summation influence of dietary uracil, a component of RNA, on the development of (pre)neoplastic lesions."3.68Summation effects of uracil and other promoters on epithelial lesion development in the F344 rat urinary bladder initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Asamoto, M; de Camargo, JL; Fukushima, S; Kato, T; Shirai, T, 1991)
"Uracil is known to cause reversible urolithiasis and to induce papillomatosis in the urinary bladder of F344 rats."3.67Summation effect of uracil on the two-stage and multistage models of urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Fukushima, S; Masui, T; Mutai, M; Shirai, T; Takahashi, S, 1988)
"Biliary papillomatosis is rare, and its pathogenic mechanisms are not yet clear."1.42Volume-reserving Surgery after Photodynamic Therapy for Biliary Papillomatosis: A Case Report. ( Cheong, CO; Kim, HK; Kim, KS; Lim, JH; Park, JS; Park, SW, 2015)
"Uracil (U) was provided through the diet in order to expand the population of initiated cells."1.29Absence of promoting potential of bracken fern (Pteridium aquilinum) in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine and uracil. ( de Camargo, JL; de Oliveira, ML; Fukushima, S; Souza Rocha, N, 1995)
"Uracil was administered for 15, 10 or 5 weeks followed by BBN for 23 weeks, the total observation time being 40 weeks."1.28Lack of synergism in rat urinary tract carcinogenesis between prior uracil treatment and N-butyl-N-(4-hydroxybutyl)-nitrosamine administration. ( Asamoto, M; Fukushima, S; Ogiso, T; Okumura, M; Shirai, T, 1991)
"Uracil has been shown to cause a strong proliferative response in the urinary bladder epithelium of rats and mice through calculus formation and, consequently, acts as a strong promoter in bladder carcinogenesis."1.28Strong promoting activity by uracil on urinary bladder carcinogenesis and a possible inhibitory effect on thyroid tumorigenesis in rats initiated with N-methyl-N-nitrosourea. ( Cohen, SM; Garland, EM; Mann, AM; Masui, T, 1989)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's8 (53.33)18.2507
2000's2 (13.33)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheong, CO1
Lim, JH1
Park, JS1
Park, SW1
Kim, HK1
Kim, KS1
Ito, A1
Asamoto, M4
Hokaiwado, N1
Takahashi, S4
Shirai, T8
Shibata, M1
Tagawa, Y2
Imaida, K1
Hirose, M1
Yamamoto, S1
Yonezawa, S1
Ichinose, M1
Miki, K1
Masui, T4
Fukushima, S10
Inoue, H1
Tatematsu, M1
de Oliveira, ML1
Souza Rocha, N1
de Camargo, JL2
Otori, K2
Yano, Y2
Takada, N2
Lee, CC1
Hayashi, S1
Otani, S2
Nomura, S1
Kitamura, Y1
Vieira de Oliveira, S1
Viana de Camargo, JL1
Cardoso, PR1
Padovani, CR1
Ogawa, K1
Kimoto, N1
Nakanishi, M1
Kato, T1
Okumura, M2
Ogiso, T1
Mann, AM1
Garland, EM1
Cohen, SM1
Ito, N2
Mutai, M1
Ikawa, E1

Other Studies

15 other studies available for uracil and Papilloma

ArticleYear
Volume-reserving Surgery after Photodynamic Therapy for Biliary Papillomatosis: A Case Report.
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2015, Volume: 66, Issue:1

    Topics: Antineoplastic Agents; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Embolization, Therapeutic; Gam

2015
Tbx3 expression is related to apoptosis and cell proliferation in rat bladder both hyperplastic epithelial cells and carcinoma cells.
    Cancer letters, 2005, Feb-28, Volume: 219, Issue:1

    Topics: Animals; Apoptosis; Base Sequence; Cell Proliferation; Gene Expression; Gene Library; Hyperplasia; I

2005
Differences in cell proliferation and apoptosis between reversible and irreversible mucosal lesions associated with uracil-induced urolithiasis in N-butyl-N-(4-hydroxybutyl)nitrosamine-pretreated.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Division; Male; Microscopy, Elec

1995
Immunohistochemically demonstrated variation in expression of cathepsin E between uracil-induced papillomatosis and N-butyl-N-(4-hydroxybutyl)nitrosamine-induced preneoplastic and neoplastic changes in rat urinary bladder.
    Virchows Archiv : an international journal of pathology, 1996, Volume: 427, Issue:6

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cathepsin E; Cathe

1996
Absence of promoting potential of bracken fern (Pteridium aquilinum) in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine and uracil.
    Teratogenesis, carcinogenesis, and mutagenesis, 1995, Volume: 15, Issue:4

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Male; Papilloma; Plants, Toxic; Rats; Rats, Wist

1995
Reversibility and apoptosis in rat urinary bladder papillomatosis induced by uracil.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Apoptosis; Cyclin D1; Cyclins; DNA Fragmentation; Immunohistochemistry; Lewis Blood Group A

1997
Expression and localization of ornithine decarboxylase in reversible papillomatosis induced by uracil in rat bladder.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:4

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Immunohistochemistry; In Situ Hybridi

1998
Effects of uracil calculi on cell growth and apoptosis in the BBN-initiated Wistar rat urinary bladder mucosa.
    Teratogenesis, carcinogenesis, and mutagenesis, 1999, Volume: 19, Issue:4

    Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Division; Hyperplasia; Male; Muc

1999
Aberrant expression of p27(Kip1) is associated with malignant transformation of the rat urinary bladder epithelium.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Cell Cycle Proteins; Cyclin D1; Cyclin E;

2000
Summation effects of uracil and other promoters on epithelial lesion development in the F344 rat urinary bladder initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:11

    Topics: Animals; Ascorbic Acid; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Butylhydrox

1991
Lack of synergism in rat urinary tract carcinogenesis between prior uracil treatment and N-butyl-N-(4-hydroxybutyl)-nitrosamine administration.
    Cancer letters, 1991, Jun-14, Volume: 58, Issue:1-2

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Kidney Neoplasms; Kidney Pelvi

1991
Strong promoting activity by uracil on urinary bladder carcinogenesis and a possible inhibitory effect on thyroid tumorigenesis in rats initiated with N-methyl-N-nitrosourea.
    Carcinogenesis, 1989, Volume: 10, Issue:8

    Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma, Transitional Cell; Male; Methylnitroso

1989
Cell proliferation induced by uracil-calculi and subsequent development of reversible papillomatosis in the rat urinary bladder.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Animals; Cell Division; Male; Microscopy, Electron, Scanning; Papilloma; Rats; Rats, Inbred F344; Ur

1989
Summation effect of uracil on the two-stage and multistage models of urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Carcinogenesis, 1988, Volume: 9, Issue:11

    Topics: Animals; Body Weight; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Carcinoma, Transitiona

1988
Uracil-induced urolithiasis and the development of reversible papillomatosis in the urinary bladder of F344 rats.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 2

    Topics: Animals; Hyperplasia; Male; Microscopy, Electron; Papilloma; Rats; Rats, Inbred F344; Uracil; Urinar

1986