Compounds > uracil
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uracil and Ovarian Neoplasms

uracil has been researched along with Ovarian Neoplasms in 24 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."7.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination."5.511-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019)
" 5-Fluorouracil (5-FU) was effective against only one bladder cancer xenograft among 6 cancer xenografts tested."3.68[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice]. ( Adachi, S; Akaza, H; Ishitsuka, H; Kanazawa, K; Miwa, M; Nitta, K; Sekiguchi, F; Tokita, H, 1991)
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."3.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
"Complete cases among them consisted of ovarian cancer 53 cases, uterine cervical cancer 86 cases and endometrial cancer 27 cases for a total of 166 cases."2.67[Maintenance chemotherapy using UFT and FT for gynecological malignant tumors. The Gunma Prefectural Society for Study of Chemotherapy for Gynecological Cancer]. ( Ibuki, Y; Igarashi, M; Ito, T; Kimura, H; Kosuge, T; Nagayama, M; Nogami, Y; Ohwada, N; Tsukagoshi, T; Yazaki, K, 1992)
"Twenty nine patients with ovarian cancer of common epitherial origin who had no evidence of disease proved by computed tomography after the initial operation and chemotherapy were studied."2.67[Evaluation of UFT administration in patients with ovarian cancer who had no evidence of disease after the initial therapy]. ( Chen, JT; Fujimoto, I; Hamada, T; Hasumi, K; Hirai, Y; Nakayama, K; Shimizu, Y; Teshima, H; Yamauchi, K; Yokosuka, K, 1990)
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination."1.511-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019)
"Advanced ovarian cancer is a chemosensitive tumor and most patients initially respond to platinum-based combination chemotherapy with response rates of about 70%, including a high proportion of complete responses."1.35Complete remission of platinium refractory ovarian cancer with second line tegafur with uracil monotherapy: a case report. ( Aslan, Y; Buyukberber, S; Camci, C; Kalender, ME; Sevinc, A, 2009)
"We report here a case of synchronous dermoid cyst with secondary malignant tumor and uterine endometrial adenocarcinoma that responded to UFT."1.33[A case of synchronous double cancer responding to UFT--dermoid cyst with secondary malignant transformation and uterine endometrial adenocarcinoma]. ( Fukai, H; Maruyama, A; Matsumoto, H; Sakamoto, H; Takami, M; Takimoto, T; Togo, Y; Yamamoto, T, 2005)
"A case of an amylase-producing ovarian cancer in 69-year-old woman has been investigated by light and electron microscopy, as well as by amylase isozyme analysis."1.27[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report]. ( Chiba, T; Hiura, M; Kaneko, H; Kawamurra, S; Moriwaki, S; Tanaka, M; Yokoyama, T, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's4 (16.67)18.2507
2000's5 (20.83)29.6817
2010's4 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, J1
Yang, X1
Li, X1
Gao, H1
Liu, N1
Guo, X1
Ziske, MA1
Pettee, KM1
Khaing, M1
Rubinic, K1
Eisenmann, KM1
Fox, BA1
Sanders, KL1
Rommereim, LM1
Guevara, RB1
Bzik, DJ1
Shindo, Y1
Tenma, K1
Okuyama, M1
Hibino, M1
Sasaki, Y1
Kitamura, T1
Nakamura, M2
Ebisui, C1
Ohkubo, K1
Akitake, H1
Ohtsuka, M1
Maekawa, T1
Yoshioka, S1
Hama, N1
Kashiwazaki, M1
Taniguchi, M1
Tsujie, M1
Konishi, M1
Fujimoto, T1
Shimizu, Y3
Katase, K1
Kobayashi, Y1
Hasumi, K2
Takami, M1
Maruyama, A1
Fukai, H1
Matsumoto, H1
Togo, Y1
Takimoto, T1
Sakamoto, H1
Yamamoto, T1
Camci, C1
Sevinc, A1
Aslan, Y1
Kalender, ME1
Buyukberber, S1
Akiyama, J2
Sagara, Y2
Takeda, Y2
Tanaka, K1
Kodama, S1
Takahashi, T1
Honma, S1
Maruhashi, T1
Tokunaga, A1
Takeuchi, Y1
Sudou, N1
Adachi, S3
Ohwada, N1
Nagayama, M1
Kosuge, T1
Tsukagoshi, T1
Ibuki, Y1
Igarashi, M1
Yazaki, K1
Ito, T1
Nogami, Y1
Kimura, H1
Miwa, M1
Sekiguchi, F1
Akaza, H1
Tokita, H1
Nitta, K1
Kanazawa, K2
Ishitsuka, H1
Chen, JT1
Nakayama, K1
Yokosuka, K1
Teshima, H1
Hirai, Y1
Hamada, T1
Fujimoto, I1
Yamauchi, K1
Ihara, T1
Hisamatsu, K1
Okamoto, E1
Suemitsu, H1
Yamada, M1
Matsuda, M1
Nanba, K1
Kirimoto, K1
Kawamurra, S1
Hiura, M1
Kaneko, H1
Yokoyama, T1
Tanaka, M1
Chiba, T1
Moriwaki, S1
Kikuchi, Y2
Oomori, K2
Iwano, I2
Kizawa, I2
Miyauchi, M2
Kita, T2
Kuki, E1
Nagai, S2
Kamiya, H2
Sato, K1
Sakai, K2
Yoshiya, N1
Misawa, Y1
Ishida, M1
Yuzawa, H1
Takeuchi, S1
Kato, K1
Sawada, T1
Tsukasaki, K1
Inoue, S1
Shibata, S1
Okumura, A1
Tanaka, T1
Onitsuka, Y1
Yoshimura, T1
Aiko, A1
Ikuta, Y1
Fukuma, K1
Matsuura, K1
Kholodnyi, MD1
Mindlin, SS1

Reviews

1 review available for uracil and Ovarian Neoplasms

ArticleYear
[Phase III study of gynecologic cancer in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:9

    Topics: Adjuvants, Immunologic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Drug Combina

2002

Trials

3 trials available for uracil and Ovarian Neoplasms

ArticleYear
[Clinical results of UFT against ovarian carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Female;

1994
[Maintenance chemotherapy using UFT and FT for gynecological malignant tumors. The Gunma Prefectural Society for Study of Chemotherapy for Gynecological Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Humans;

1992
[Evaluation of UFT administration in patients with ovarian cancer who had no evidence of disease after the initial therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

1990

Other Studies

20 other studies available for uracil and Ovarian Neoplasms

ArticleYear
1-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:16

    Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Adhesion; Cell Line, Tumor; Female; Focal Adhesion Kina

2019
SMIFH2-mediated mDia formin functional inhibition potentiates chemotherapeutic targeting of human ovarian cancer spheroids.
    Biochemical and biophysical research communications, 2016, Mar-25, Volume: 472, Issue:1

    Topics: Actins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovarian Epithelial; Carrier Prote

2016
Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity.
    PLoS genetics, 2016, Volume: 12, Issue:7

    Topics: Animals; Antigens, Protozoan; Cancer Vaccines; Dendritic Cells; Female; Host-Pathogen Interactions;

2016
[A case of simultaneous bilateral metastatic ovarian tumor of colon cancer followed by FOLFOX4 Regimen and oral tegafur/uracil+oral leucovorin after R0 operation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colectomy; C

2009
[A case of ovarian metastasis from colon cancer successfully treated with multidisciplinary therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe

2010
[Chemotherapy with combination of UFT and cisplatin against metastatic ovarian tumor originating from gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring

2004
[A case of synchronous double cancer responding to UFT--dermoid cyst with secondary malignant transformation and uterine endometrial adenocarcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Carcinoma, Adenosquamous; Combined Modality Therapy; D

2005
Complete remission of platinium refractory ovarian cancer with second line tegafur with uracil monotherapy: a case report.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Combined Modality Therapy; Cys

2009
[Effective cases of advanced endometrial and recurrent ovarian cancers treated with oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Tra

1984
[Clinical effects of oral administration of UFT on gynecological malignant tumors].
    Nihon Sanka Fujinka Gakkai zasshi, 1984, Volume: 36, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

1984
[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine;

1991
[Transformation of ovarian yolk sac tumor to immature teratoma following chemotherapy].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:5

    Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female;

1985
[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:4

    Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Female; Humans; Middle

1988
Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas.
    Gynecologic oncology, 1989, Volume: 35, Issue:2

    Topics: Animals; Calmodulin; Carcinoma; Drug Combinations; Drug Synergism; Female; Fluorouracil; Mice; Mice,

1989
[In vitro effects of 5-FU on gynecologic malignant tumor cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Cells, Cultured; Colony-Fo

1986
[Antitumor effect of UFT on human ovarian cancer grafted to nude mice and 5-FU concentration in tumor and normal tissues].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Mi

1988
[Effect of calmodulin antagonists (W-5 and W-7) on antitumor activity of Tegafur and UFT (Tegafur plus uracil)].
    Nihon Sanka Fujinka Gakkai zasshi, 1988, Volume: 40, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calmodulin; Drug Synergism; Female; Mice; M

1988
[Preoperative treatment with UFT for patients with ovarian malignant tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Middle Ag

1985
[UFT concentration in serum and tissues of patients with gynecologic malignant tumors following oral administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Endometrium; Female; Genital Neoplasms, Female; Huma

1985
[The hypoplastic state of hematopoiesis following chemotherapy with alkylating compounds].
    Voprosy onkologii, 1969, Volume: 15, Issue:8

    Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Female; Hematologic Disease

1969