uracil has been researched along with Necrosis in 10 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized controlled trial was conducted to determine whether pathologic necrosis in response to preoperative treatment with uracil-tegafur(UFT) could be used to identify patients with colorectal cancer most likely to benefit from postoperative adjuvant therapy with the drug." | 9.13 | Clinical identification of colorectal cancer patients benefiting from adjuvant uracil-tegafur (UFT): a randomized controlled trial. ( Fujii, M; Kochi, M; Takayama, T, 2008) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 7.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| "A randomized controlled trial was conducted to determine whether pathologic necrosis in response to preoperative treatment with uracil-tegafur(UFT) could be used to identify patients with colorectal cancer most likely to benefit from postoperative adjuvant therapy with the drug." | 5.13 | Clinical identification of colorectal cancer patients benefiting from adjuvant uracil-tegafur (UFT): a randomized controlled trial. ( Fujii, M; Kochi, M; Takayama, T, 2008) |
| "This study was designed to determine if histopathologic evaluation of patients with resectable colorectal cancer following preoperative chemotherapy with uracil and tegafur with a molar ratio of 4:1 (UFT) could predict chemosensitivity to postoperative fluoropyrimidines to prevent recurrence of disease." | 5.09 | Using preoperative UFT to predict sensitivity to fluoropyrimidines in colorectal cancer. ( Fujii, M, 1999) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 3.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| " Adverse effects of CYN were monitored up to 7 weeks post-dosing by clinical examination, histopathology, biochemistry and gene expression." | 1.37 | Toxicity and recovery in the pregnant mouse after gestational exposure to the cyanobacterial toxin, cylindrospermopsin. ( Bradfield, CA; Chernoff, N; Gage, MI; Jaskot, RH; Liu, Y; Malarkey, DE; Richards, JH; Rogers, EH; Rosen, MB; Schmid, JE; Wood, CR; Zehr, RD, 2011) |
| "A case of an amylase-producing ovarian cancer in 69-year-old woman has been investigated by light and electron microscopy, as well as by amylase isozyme analysis." | 1.27 | [Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report]. ( Chiba, T; Hiura, M; Kaneko, H; Kawamurra, S; Moriwaki, S; Tanaka, M; Yokoyama, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vanova, T | 1 |
| Raska, J | 1 |
| Babica, P | 1 |
| Sovadinova, I | 1 |
| Kunova Bosakova, M | 1 |
| Dvorak, P | 1 |
| Blaha, L | 1 |
| Rotrekl, V | 1 |
| Fujii, M | 3 |
| Takayama, T | 1 |
| Kochi, M | 2 |
| Polak, MB | 1 |
| Valamanesh, F | 1 |
| Felt, O | 1 |
| Torriglia, A | 1 |
| Jeanny, JC | 1 |
| Bourges, JL | 1 |
| Rat, P | 1 |
| Thomas-Doyle, A | 1 |
| BenEzra, D | 1 |
| Gurny, R | 1 |
| Behar-Cohen, F | 1 |
| Chernoff, N | 1 |
| Rogers, EH | 1 |
| Zehr, RD | 1 |
| Gage, MI | 1 |
| Malarkey, DE | 1 |
| Bradfield, CA | 1 |
| Liu, Y | 1 |
| Schmid, JE | 1 |
| Jaskot, RH | 1 |
| Richards, JH | 1 |
| Wood, CR | 1 |
| Rosen, MB | 1 |
| LEEVY, CM | 1 |
| TEN-HOVE, W | 1 |
| FRANK, O | 1 |
| BAKER, H | 1 |
| Lankoff, A | 1 |
| Wojcik, A | 1 |
| Lisowska, H | 1 |
| Bialczyk, J | 1 |
| Dziga, D | 1 |
| Carmichael, WW | 1 |
| Ueda, H | 1 |
| Tanaka, H | 1 |
| Kida, Y | 1 |
| Fukuchi, H | 1 |
| Ichinose, M | 1 |
| Wakabayashi, K | 1 |
| Konomi, K | 1 |
| Yamagata, M | 1 |
| Iwai, S | 1 |
| Tanaka, T | 1 |
| Kawamurra, S | 1 |
| Hiura, M | 1 |
| Kaneko, H | 1 |
| Yokoyama, T | 1 |
| Tanaka, M | 1 |
| Chiba, T | 1 |
| Moriwaki, S | 1 |
3 trials available for uracil and Necrosis
| Article | Year |
|---|---|
Clinical identification of colorectal cancer patients benefiting from adjuvant uracil-tegafur (UFT): a randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2008 |
Adjuvant chemotherapy with tegafur/uracil administration after transcatheter arterial chemoembolization for advanced hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Combined Mo | 2008 |
Using preoperative UFT to predict sensitivity to fluoropyrimidines in colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, | 1999 |
7 other studies available for uracil and Necrosis
| Article | Year |
|---|---|
Freshwater Cyanotoxin Cylindrospermopsin Has Detrimental Stage-specific Effects on Hepatic Differentiation From Human Embryonic Stem Cells.
Topics: Albumins; Alkaloids; Apoptosis; Bacterial Toxins; Cell Differentiation; Cell Survival; Cyanobacteria | 2019 |
Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma.
Topics: Animals; Antimitotic Agents; Apoptosis; Blister; Cell Death; Cell Proliferation; Cell Survival; Cell | 2008 |
Toxicity and recovery in the pregnant mouse after gestational exposure to the cyanobacterial toxin, cylindrospermopsin.
Topics: Alkaloids; Animals; Bacterial Toxins; Biomarkers; Cyanobacteria; Cyanobacteria Toxins; Embryo Loss; | 2011 |
FOLIC ACID DEFICIENCY AND HEPATIC DNA SYNTHESIS.
Topics: Avitaminosis; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; Folic Aci | 1964 |
No induction of structural chromosomal aberrations in cylindrospermopsin-treated CHO-K1 cells without and with metabolic activation.
Topics: Alkaloids; Animals; Apoptosis; Bacterial Toxins; Biotransformation; CHO Cells; Chromosome Aberration | 2007 |
[A case of colon cancer with severe anal bleeding caused in a preoperative chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Adult; Anal Canal; Antineoplastic Combined Chemotherapy Protoc | 1991 |
[Amylase-producing ovarian cancer treated with postoperative QF chemotherapy--a case report].
Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Female; Humans; Middle | 1988 |