Page last updated: 2024-10-20

uracil and Malaria

uracil has been researched along with Malaria in 5 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions."7.67[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989)
"Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions."3.67[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delia, TJ1
Scovill, JP1
Munslow, WD1
Burckhalter, JH1
Huang, ZY1
Chang, HL1
Wu, KY1
Wang, JJ1
Scott, HV1
Gero, AM1
O'Sullivan, WJ1
Warhurst, DC2
Robinson, BL2
Howells, RE1
Peters, W1

Other Studies

5 other studies available for uracil and Malaria

ArticleYear
Synthesis of 5-substituted aminomethyluracils via the Mannich reaction.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:2

    Topics: Animals; Chickens; Leukemia L1210; Magnetic Resonance Spectroscopy; Malaria; Malaria, Avian; Mice; P

1976
[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2

    Topics: Alloxan; Animals; Antimalarials; Female; Glutathione Reductase; Hemolysis; Malaria; Mice; Plasmodium

1989
In vitro inhibition of Plasmodium falciparum by pyrazofurin, an inhibitor of pyrimidine biosynthesis de novo.
    Molecular and biochemical parasitology, 1986, Volume: 18, Issue:1

    Topics: Amides; Chloroquine; Culture Media; Erythrocytes; Humans; Malaria; Male; Middle Aged; Orotate Phosph

1986
Cytotoxic agents and haemozoin pigment in malaria parasites (Plasmodium berghei).
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jul-08, Volume: 10, Issue:13

    Topics: Animals; Antineoplastic Agents; Azaserine; Chloramphenicol; Chloroquine; Cycloheximide; Cytoplasm; D

1971
The effect of cytotoxic agents on autophagic vacuole formation in chloroquine-treated malaria parasites (Plasmodium berghei).
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jul-08, Volume: 10, Issue:13

    Topics: Animals; Antineoplastic Agents; Azaserine; Chloroquine; Colchicine; Cycloheximide; Cytoplasm; Dactin

1971