uracil has been researched along with Liver Neoplasms in 307 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Regorafenib and TAS-102 are standard treatment options in refractory metastatic colorectal cancer based on improvement in overall survival by 6 and 8 weeks, respectively, when compared with best supportive care alone (BSC)." | 9.27 | Cost-effectiveness Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer in the United States. ( Barzi, A; Cho, SK; Hay, JW, 2018) |
| "We investigated the efficacy and safety of oral Uracil/tegafur (UFT) with leucovorin and mitomycin C (MMC) as third-line treatment for patients with extensively pretreated metastatic colorectal cancer (mCRC)." | 9.16 | Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. ( Chamorey, E; Dahan, L; Evesque, L; Follana, P; Francois, E; Mari, V; Michel, C; Perrier, H; Seitz, JF; Smith, D, 2012) |
| "To evaluate the efficacy and tolerability of systemic chemotherapy with irinotecan (CPT-11), UFT and leucovorin (LV) combined with hepatic arterial infusion (HAI) consisting of 5-fluorouracil (5-FU) in colorectal cancer patients with unresectable liver metastases." | 9.15 | Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases. ( Matsumoto, H; Mori, T; Takahashi, K; Yamaguchi, T; Yasutome, M, 2011) |
| "The aim was to determine the recommended dose of combined chemotherapy with mitoxantrone and uracil/tegafur (Phase I part) and to clarify its efficacy and safety in patients with advanced hepatocellular carcinoma at the recommended dose (Phase II part)." | 9.15 | A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma. ( Furuse, J; Ikeda, M; Ishii, H; Mitsunaga, S; Morizane, C; Nakachi, K; Okusaka, T; Suzuki, E; Ueno, H, 2011) |
| "Sorafenib plus metronomic tegafur/uracil therapy can induce tumor stabilization in advanced hepatocellular carcinoma (HCC) patients." | 9.15 | Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil. ( Chen, BB; Cheng, AL; Hsu, C; Hsu, CH; Hsu, CY; Hu, FC; Shen, YC; Shih, TT; Wei, SY; Yu, CW, 2011) |
| "Eniluracil (EU) is a potent dihydropyrimidine (DPD) inhibitor, which improves the oral bio-availability of 5-fluorouracil (5-FU) and may overcome fluoropyrimidine (FP) resistance in hepatocellular carcinoma (HCC)." | 9.15 | Final results of a prematurely discontinued Phase 1/2 study of eniluracil with escalating doses of 5-fluorouracil administered orally in patients with advanced hepatocellular carcinoma. ( Chang, AY; de Lima Lopes, G; Dicksey, JS; Palalay, M; Peters, WP, 2011) |
| "Thirty-one patients with non-resectable, colorectal cancer (CRC) liver metastases received irinotecan 120 mg/m(2), followed by leucovorin (LV) 20 mg/m(2) and 5-fluorouracil (5-FU) 500 mg/m(2) administered by HAI every 2 weeks, plus UFT (tegafur-uracil) 200 mg/m(2)/day with LV 30 mg/day on days 1-22, followed by a 6-day rest." | 9.14 | Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer. ( Ariche, A; Baruch, NB; Brenner, B; Dinerman, M; Greif, F; Idelevich, E; Kashtan, H; Mavor, E; Miller, R; Shani, A; Susmalian, S, 2009) |
| "Sorafenib, a multi-kinase inhibitor with anti-angiogenic activity, was recently approved for the treatment of advanced hepatocellular carcinoma (HCC)." | 9.14 | Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. ( Chen, PJ; Cheng, AL; Ding, YH; Hsu, C; Hsu, CH; Lin, ZZ; Shao, YY; Shen, YC, 2010) |
| "This multicenter, open-label study evaluated a 28-day oral regimen of 5-FU (1 mg/m2 twice daily) plus the dihydropyrimidine dehydrogenase inhibitor, eniluracil (10 mg/m2 twice daily), in patients with chemotherapy-naive or anthracycline-refractory inoperable hepatocellular carcinoma." | 9.10 | Oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma. ( Abramson, N; Benson, AB; Bonny, T; Burnhan, JP; Hohneker, J; Klencke, B; Levin, J; McGuirt, C; Mitchell, E; Ritch, P, 2002) |
| "A prospective randomized trial was conducted to evaluate the efficacy of long-term oral administration of low-dose tegafur combined with uracil as an adjuvant chemotherapy, following transcatheter arterial embolization (TAE) in 40 patients with hepatocellular carcinoma (HCC)." | 9.08 | A prospective randomized evaluation of a compound of tegafur and uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization. ( Arase, Y; Chayama, K; Ikeda, K; Koida, I; Kumada, H; Saitoh, S; Tsubota, A, 1995) |
| "We report a case of multiple lung metastases from hepatocellular carcinoma(HCC)successfully treated by oral administration of tegafur/uracil(UFT)." | 8.89 | [Complete remission of hepatocellular carcinoma with multiple lung metastases by oral administration of tegafur/uracil]. ( Hatano, E; Koyama, Y; Takada, Y; Tanabe, K; Taura, K; Uemoto, S, 2013) |
| "The RECOURSE trial supported trifluridine/tipiracil as a treatment option in metastatic colorectal cancer (mCRC)." | 8.12 | The effect of prognostic factors at baseline on the efficacy of trifluridine/tipiracil in patients with metastatic colorectal cancer: A Portuguese exploratory analysis. ( Basto, R; Bonito, N; Gomes, I; Jacinto, P; Magalhães, J; Paulo, J; Pereira, TC; Sousa, G; Sousa, MJ, 2022) |
| "This study compared the efficacy of regorafenib and trifluridine/tipiracil (TFTD) in patients with metastatic colorectal cancer (mCRC) who are refractory to standard chemotherapy, because despite their clinical approval, it still remains unclear which of these two drugs should be used as initial treatment." | 7.88 | Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study. ( Baba, E; Denda, T; Enomoto, M; Esaki, T; Fukuoka, S; Gosho, M; Ishikawa, T; Kajiwara, T; Kashiwada, T; Komatsu, Y; Kumekawa, Y; Makiyama, C; Moriwaki, T; Okuyama, H; Sakai, D; Satake, H; Shimada, Y; Sugimoto, N; Sugiyama, M; Suto, T; Takashima, A; Tamura, T; Taniguchi, H; Watanabe, T; Yamashita, K; Yamazaki, K, 2018) |
| " The study included patients from 16 hepatologic centres involved in the AMBER, investigator-initiated study on treatment of chronic hepatitis C patients within a programme preceding EU registration of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin." | 7.88 | Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real-world experience study. ( Berak, H; Białkowska, J; Bolewska, B; Fleischer-Stępniewska, K; Flisiak, R; Garlicki, A; Janczewska, E; Karpińska, E; Karwowska, K; Nazzal, K; Piekarska, A; Simon, K; Tomasiewicz, K; Tronina, O; Tuchendler, E; Zarębska-Michaluk, D; Łucejko, M, 2018) |
| "We observed a sustained viral response (SVR) of ombitasvir/paritaprevir/ritonavir, dasabuvir and ribavirin therapy, for 12 wk, in two cases with compensated liver cirrhosis and fully destroyed early hepatocellular carcinoma (HCC)." | 7.83 | Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma. ( Antonov, K; Atanasova, E; Boyanova, Y; Jelev, D; Krastev, Z; Mateva, L; Petkova, T; Tomov, B; Zheleva, N, 2016) |
| "Oral tegafur/uracil therapy has been indicated for patients with hepatocellular carcinoma (HCC) and is often used as a single-agent treatment." | 7.79 | Genetic polymorphisms of enzymes related to oral tegafur/uracil therapeutic efficacy in patients with hepatocellular carcinoma. ( Akizuki, S; Fushiya, N; Nishino, H; Ohnishi, A; Takagi, I, 2013) |
| "Multidrug resistant H22 (H22/FAP) hepatocellular carcinoma cells were produced in vitro by continuous exposure to increasing doses of doxorubicin, cisplatin and 5-fluorouracil (FAP regimen)." | 7.79 | Association between reversal of multidrug resistance by methyl jasmonate and P-glycoprotein ATPase activity in hepatocellular carcinoma. ( Huang, FZ; Jiang, XZ; Liu, XY; Nie, WP; Wang, CF; Wang, YQ, 2013) |
| "A 65-year-old woman who had diffuse hepatocellular carcinoma(HCC)with tumor thrombus of right portalvein(Vp3) and lung metastases(Stage IVB)was treated by single-agent therapy with tegafur/uracil(UFT)." | 7.76 | [A case of hepatocellular carcinoma with portal vein thrombus(Vp3)and lung metastases(stage IVB),which responded completely to treatment with Tegafur/Uracil]. ( Adachi, K; Hiramatsu, S; Kurai, O; Miyano, M; Oka, H; Sasaki, E; Yamasaki, T, 2010) |
| "We herein report the complete remission of multiple recurrent hepatocellular carcinomas (HCCs) by the oral administration of tegafur/uracil (UFT) alone." | 7.75 | Complete remission of multiple recurrent hepatocellular carcinomas by oral administration of enteric-coated tegafur/uracil in a patient with huge hepatocellular carcinoma extending to the inferior vena cava after hepatic resection: analysis of mRNA expres ( Asakawa, M; Fujii, H; Kono, H; Matsuda, M; Shiba, S, 2009) |
| "The 5 fluorouracil hepato-arterial infusion (5-FU HAI) therapy has a good effect on the liver metastases of colorectal cancer." | 7.72 | [The 5-fluorouracil hepato-arterial infusion with oral UFT therapy for the hepatic and extra hepatic metastases of colorectal cancer]. ( Ebuchi, M; Hasegawa, K; Kato, K; Koide, A; Maruyama, M; Maruyama, S; Ohbu, M; Takashima, I, 2004) |
| "We report a case of complete remission of multiple hepatocellular carcinomas after oral administration of enteric-coated tegafur/uracil." | 7.70 | Complete remission of multiple hepatocellular carcinomas associated with hepatitis C virus-related, decompensated liver cirrhosis by oral administration of enteric-coated tegafur/uracil. ( Asakura, H; Ebe, Y; Ichida, T; Ishikawa, T; Ishimoto, Y; Naito, M; Nomoto, M; Usuda, H; Yokoyama, J, 1999) |
| " He had nausea, vomiting and anorexia due to pyloric stenosis, and was treated with 600 mg of UFT E granules/day orally for 5 consecutive days followed by 2 drug-free days (weekly-5 method), and 2 mg of lentinan intravenously twice a week." | 7.70 | [A case of advanced gastric cancer (type 3) with pyloric stenosis, multiple liver and lymph node metastases responding to UFT-E granules and lentinan]. ( Kondo, M; Takahashi, S; Takemura, T; Yoshikawa, T, 2000) |
| "We report a case of advanced hepatocellular carcinoma (HCC), successfully treated by a combination therapy of alpha-interferon (IFN-alpha) and tegafur/uracil (UFT)." | 7.70 | Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of alpha-interferon and oral tegafur/uracil. ( Dono, K; Eguchi, H; Gotoh, M; Kishimoto, S; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Sakon, M; Umeshita, K, 2000) |
| " In 22 resected patients with hepatocellular carcinoma (HCC), the concentrations of 5-fluorouracil (5-FU), tegafur and uracil were estimated in the serum, liver and cancer tissues after oral administration of UFT (tegafur, 300mg) before operation." | 7.67 | [5-Fluorouracil, tegafur, and uracil concentrations in serum and tissue of the patients with hepatocellular carcinoma after UFT administration]. ( Suenaga, M, 1987) |
| "A Phase II study of co-administration of uracil and tegafur (UFT) was performed in 32 patients with unresectable hepatocellular carcinoma." | 7.67 | Phase II study of co-administration of uracil and tegafur (UFT) in hepatocellular carcinoma. Tokyo Liver Cancer Chemotherapy Study Group. ( , 1985) |
| "Recurrence of hepatocellular carcinoma (HCC) after surgery is frequent, and is an important factor adversely influencing the long-term survival of patients." | 6.82 | Administration of adjuvant oral tegafur/uracil chemotherapy post hepatocellular carcinoma resection: A randomized controlled trial. ( Ishizuka, M; Iso, Y; Kato, M; Kubota, K; Nemoto, T; Shimoda, M; Tago, K, 2016) |
| "8% and grade 3 or higher adverse events occurred in 12." | 6.79 | A combination of oral uracil-tegafur plus leucovorin (UFT + LV) is a safe regimen for adjuvant chemotherapy after hepatectomy in patients with colorectal cancer: safety report of the UFT/LV study. ( Hasegawa, K; Ijichi, M; Kawasaki, S; Kokudo, N; Koyama, H; Makuuchi, M; Miyagawa, S; Oba, M; Saiura, A; Takayama, T; Teruya, M; Yamamoto, J; Yoshimi, F, 2014) |
| "From 2002 to 2007, a total of 10 consecutive patients with Stage IVA HCC accompanied by PVTT were studied prospectively to examine the efficacy of treatment by intra-arterial infusion of a chemotherapeutic agents consisting of etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil." | 6.73 | Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-arterial chemotherapy combining etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil: a p ( Imai, M; Ishikawa, T; Kamimura, H; Kamimura, T; Ohta, H; Seki, K; Togashi, T; Tsuchiya, A; Watanabe, K; Yoshida, T, 2007) |
| "Standard chemotherapy for advanced biliary tract cancer has not been established." | 6.72 | Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer. ( Funakoshi, A; Furuse, J; Horikawa, Y; Ikeda, M; Ishii, H; Mizuno, N; Morizane, C; Nagase, M; Nakachi, K; Okusaka, T; Ueno, H; Yamao, K, 2006) |
| "Frequent recurrence of hepatocellular carcinoma (HCC) after surgery remains a major clinical problem." | 6.72 | Uracil-tegafur as an adjuvant for hepatocellular carcinoma: a randomized trial. ( Hasegawa, K; Ijichi, M; Imamura, H; Kokudo, N; Makuuchi, M; Matsuyama, Y; Sano, K; Sugawara, Y; Takayama, T, 2006) |
| " A phase II clinical trial of this combination using a continuous dosing schedule was carried out in patients with metastatic colorectal cancer." | 6.70 | Eastern Cooperative Oncology Group phase II trial (E4296) of oral 5-fluorouracil and eniluracil as a 28-day regimen in metastatic colorectal cancer. ( Benson, AB; Catalano, P; Cornfeld, MJ; Graham, DL; Huang, J; Marsh, JC; O'Dwyer, PJ, 2002) |
| "Only a minority of patients with hepatocellular carcinoma (HCC) may benefit from curative treatments, whereas there is no standard therapy for the remaining patients." | 6.70 | A phase II trial of oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma. ( Bruix, J; Castells, L; El-Hariry, I; Llovet, JM; Peachey, M; Ruff, P; Tassopoulos, N, 2001) |
| "Patients with hepatocellular carcinoma (HCC) are highly compromised by failing liver function." | 6.68 | A pharmacological pilot study: application of an intermittent schedule of oral uracil and ftorafur (UFT) for hepatocellular carcinoma patients. ( Haneda, T; Kamiyama, T; Nakanishi, K; Nishibe, M; Shimamura, T; Uchino, J; Une, Y, 1996) |
| "Alogliptin is an anti-diabetic that may have effective anticancer properties against many types of malignancies." | 5.62 | Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis. ( Abd Elmaaboud, MA; Arab, HH; Kabel, AM, 2021) |
| "Regorafenib and TAS-102 are standard treatment options in refractory metastatic colorectal cancer based on improvement in overall survival by 6 and 8 weeks, respectively, when compared with best supportive care alone (BSC)." | 5.27 | Cost-effectiveness Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer in the United States. ( Barzi, A; Cho, SK; Hay, JW, 2018) |
| "We investigated the efficacy and safety of oral Uracil/tegafur (UFT) with leucovorin and mitomycin C (MMC) as third-line treatment for patients with extensively pretreated metastatic colorectal cancer (mCRC)." | 5.16 | Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. ( Chamorey, E; Dahan, L; Evesque, L; Follana, P; Francois, E; Mari, V; Michel, C; Perrier, H; Seitz, JF; Smith, D, 2012) |
| "To evaluate the efficacy and tolerability of systemic chemotherapy with irinotecan (CPT-11), UFT and leucovorin (LV) combined with hepatic arterial infusion (HAI) consisting of 5-fluorouracil (5-FU) in colorectal cancer patients with unresectable liver metastases." | 5.15 | Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases. ( Matsumoto, H; Mori, T; Takahashi, K; Yamaguchi, T; Yasutome, M, 2011) |
| "The aim was to determine the recommended dose of combined chemotherapy with mitoxantrone and uracil/tegafur (Phase I part) and to clarify its efficacy and safety in patients with advanced hepatocellular carcinoma at the recommended dose (Phase II part)." | 5.15 | A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma. ( Furuse, J; Ikeda, M; Ishii, H; Mitsunaga, S; Morizane, C; Nakachi, K; Okusaka, T; Suzuki, E; Ueno, H, 2011) |
| "Sorafenib plus metronomic tegafur/uracil therapy can induce tumor stabilization in advanced hepatocellular carcinoma (HCC) patients." | 5.15 | Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil. ( Chen, BB; Cheng, AL; Hsu, C; Hsu, CH; Hsu, CY; Hu, FC; Shen, YC; Shih, TT; Wei, SY; Yu, CW, 2011) |
| "Eniluracil (EU) is a potent dihydropyrimidine (DPD) inhibitor, which improves the oral bio-availability of 5-fluorouracil (5-FU) and may overcome fluoropyrimidine (FP) resistance in hepatocellular carcinoma (HCC)." | 5.15 | Final results of a prematurely discontinued Phase 1/2 study of eniluracil with escalating doses of 5-fluorouracil administered orally in patients with advanced hepatocellular carcinoma. ( Chang, AY; de Lima Lopes, G; Dicksey, JS; Palalay, M; Peters, WP, 2011) |
| "Thirty-one patients with non-resectable, colorectal cancer (CRC) liver metastases received irinotecan 120 mg/m(2), followed by leucovorin (LV) 20 mg/m(2) and 5-fluorouracil (5-FU) 500 mg/m(2) administered by HAI every 2 weeks, plus UFT (tegafur-uracil) 200 mg/m(2)/day with LV 30 mg/day on days 1-22, followed by a 6-day rest." | 5.14 | Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer. ( Ariche, A; Baruch, NB; Brenner, B; Dinerman, M; Greif, F; Idelevich, E; Kashtan, H; Mavor, E; Miller, R; Shani, A; Susmalian, S, 2009) |
| "Sorafenib, a multi-kinase inhibitor with anti-angiogenic activity, was recently approved for the treatment of advanced hepatocellular carcinoma (HCC)." | 5.14 | Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma. ( Chen, PJ; Cheng, AL; Ding, YH; Hsu, C; Hsu, CH; Lin, ZZ; Shao, YY; Shen, YC, 2010) |
| "This multicenter, open-label study evaluated a 28-day oral regimen of 5-FU (1 mg/m2 twice daily) plus the dihydropyrimidine dehydrogenase inhibitor, eniluracil (10 mg/m2 twice daily), in patients with chemotherapy-naive or anthracycline-refractory inoperable hepatocellular carcinoma." | 5.10 | Oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma. ( Abramson, N; Benson, AB; Bonny, T; Burnhan, JP; Hohneker, J; Klencke, B; Levin, J; McGuirt, C; Mitchell, E; Ritch, P, 2002) |
| "Two studies were carried out to determine the activity and evaluate the toxicity of oral chemotherapy with uracil and tegafur in a 4:1 molar ratio (UFT) plus or minus calcium folinate in elderly patients with advanced colorectal cancer." | 5.09 | UFT plus or minus calcium folinate for metastatic colorectal cancer in older patients. ( Abad, A; Antón, A; Aranda, E; Carrato, A; Cervantes, A; Díáz-Rubio, E; Fernández Martos, C; Gallén, M; Marcuello, E; Massuti, T; Navarro, M; Rifá, J; Sastre, J, 1999) |
| "A prospective randomized trial was conducted to evaluate the efficacy of long-term oral administration of low-dose tegafur combined with uracil as an adjuvant chemotherapy, following transcatheter arterial embolization (TAE) in 40 patients with hepatocellular carcinoma (HCC)." | 5.08 | A prospective randomized evaluation of a compound of tegafur and uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization. ( Arase, Y; Chayama, K; Ikeda, K; Koida, I; Kumada, H; Saitoh, S; Tsubota, A, 1995) |
| "Uracil (UFT) was administrated to 90 patients with advanced hepatocellular carcinoma for whom transcatheter arterial embolization was applied." | 5.07 | [Randomized trial-comparing UFT and FT in the treatment of advanced hepatocellular carcinoma (second report: well controlled study on patients with transcatheter arterial embolization) Osaka Research Society for Liver, Gallbladder and Pancreas]. ( Kamata, T; Kojima, J; Monna, T, 1992) |
| "In a randomized trial, Tegafur (FT-207) or Tegafur-Uracil (UFT) was administrated to 76 patients with advanced hepatocellular carcinoma for whom transcatheter arterial embolization could not be applied." | 5.06 | [Randomized trial comparing UFT and FT-207 in the treatment of advanced hepatocellular carcinoma (first report: well controlled study on the patients for whom transcatheter arterial embolization could not be applied) Osaka Research Society for Liver, Gall ( Kamata, T; Kojima, J; Monna, T, 1990) |
| "We report a case of multiple lung metastases from hepatocellular carcinoma(HCC)successfully treated by oral administration of tegafur/uracil(UFT)." | 4.89 | [Complete remission of hepatocellular carcinoma with multiple lung metastases by oral administration of tegafur/uracil]. ( Hatano, E; Koyama, Y; Takada, Y; Tanabe, K; Taura, K; Uemoto, S, 2013) |
| "5-fluorouracil (5-FU) plus leucovorin (LV) therapy is the most widely used regimen with a high evidence as the first-line treatment for advanced colorectal cancer (CRC), as well as CPT-11 as the second-line." | 4.82 | [Chemotherapy for colorectal carcinoma]. ( Enomoto, M; Higuchi, T; Sugihara, K; Uetake, H, 2003) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "The RECOURSE trial supported trifluridine/tipiracil as a treatment option in metastatic colorectal cancer (mCRC)." | 4.12 | The effect of prognostic factors at baseline on the efficacy of trifluridine/tipiracil in patients with metastatic colorectal cancer: A Portuguese exploratory analysis. ( Basto, R; Bonito, N; Gomes, I; Jacinto, P; Magalhães, J; Paulo, J; Pereira, TC; Sousa, G; Sousa, MJ, 2022) |
| "Combination therapy of tegafur/uracil (UFT) and leucovorin (LV) is widely used to treat colorectal cancers." | 4.02 | Simultaneous quantification method for 5-FU, uracil, and tegafur using UPLC-MS/MS and clinical application in monitoring UFT/LV combination therapy after hepatectomy. ( Endo, Y; Hirashita, T; Inomata, M; Itoh, H; Iwao, M; Iwashita, Y; Masuda, T; Shiraiwa, K; Suzuki, Y; Tada, K; Tanaka, R; Uchida, H, 2021) |
| "This study compared the efficacy of regorafenib and trifluridine/tipiracil (TFTD) in patients with metastatic colorectal cancer (mCRC) who are refractory to standard chemotherapy, because despite their clinical approval, it still remains unclear which of these two drugs should be used as initial treatment." | 3.88 | Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study. ( Baba, E; Denda, T; Enomoto, M; Esaki, T; Fukuoka, S; Gosho, M; Ishikawa, T; Kajiwara, T; Kashiwada, T; Komatsu, Y; Kumekawa, Y; Makiyama, C; Moriwaki, T; Okuyama, H; Sakai, D; Satake, H; Shimada, Y; Sugimoto, N; Sugiyama, M; Suto, T; Takashima, A; Tamura, T; Taniguchi, H; Watanabe, T; Yamashita, K; Yamazaki, K, 2018) |
| " The study included patients from 16 hepatologic centres involved in the AMBER, investigator-initiated study on treatment of chronic hepatitis C patients within a programme preceding EU registration of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin." | 3.88 | Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real-world experience study. ( Berak, H; Białkowska, J; Bolewska, B; Fleischer-Stępniewska, K; Flisiak, R; Garlicki, A; Janczewska, E; Karpińska, E; Karwowska, K; Nazzal, K; Piekarska, A; Simon, K; Tomasiewicz, K; Tronina, O; Tuchendler, E; Zarębska-Michaluk, D; Łucejko, M, 2018) |
| " The patients were taking sorafenib for advanced hepatocellular carcinoma and received OBV/PTV/r+DSV for 12 weeks." | 3.88 | Concomitant use of sorafenib with ombitasvir/paritaprevir/ritonavir and dasabuvir: Effectiveness and safety in clinical practice. ( Giménez-Manzorro, A; Herranz-Alonso, A; Matilla-Peña, A; Revuelta-Herrero, JL; Sanjurjo-Sáez, M, 2018) |
| "A total of 550 patients with mCRC who were registered in the REGOTAS study (Regorafenib versus TAS-102 as Salvage-line in patients with colorectal cancer refractory to standard chemotherapies: a multicenter observational study, UMIN 000020416) and treated with trifluridine/tipiracil (TFTD) or regorafenib as a later-line therapy were retrospectively stratified according to the modified Glasgow Prognostic Score (mGPS), which divided patients into mGPS 0 to 2 by serum albumin and C-reactive protein, and compared." | 3.88 | Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer. ( Baba, E; Denda, T; Esaki, T; Fukuoka, S; Ishikawa, T; Ito, M; Kajiwara, T; Kashiwada, T; Katsumata, K; Kishimoto, J; Komatsu, Y; Kumekawa, Y; Makiyama, A; Moriwaki, T; Oki, E; Okuyama, H; Sakai, D; Satake, H; Shimada, Y; Sugimoto, N; Suto, T; Takashima, A; Tamura, T; Taniguchi, H; Tsuchihashi, K; Ueno, H; Yamashita, K; Yamazaki, K, 2018) |
| "We observed a sustained viral response (SVR) of ombitasvir/paritaprevir/ritonavir, dasabuvir and ribavirin therapy, for 12 wk, in two cases with compensated liver cirrhosis and fully destroyed early hepatocellular carcinoma (HCC)." | 3.83 | Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma. ( Antonov, K; Atanasova, E; Boyanova, Y; Jelev, D; Krastev, Z; Mateva, L; Petkova, T; Tomov, B; Zheleva, N, 2016) |
| "Oral tegafur/uracil therapy has been indicated for patients with hepatocellular carcinoma (HCC) and is often used as a single-agent treatment." | 3.79 | Genetic polymorphisms of enzymes related to oral tegafur/uracil therapeutic efficacy in patients with hepatocellular carcinoma. ( Akizuki, S; Fushiya, N; Nishino, H; Ohnishi, A; Takagi, I, 2013) |
| "Multidrug resistant H22 (H22/FAP) hepatocellular carcinoma cells were produced in vitro by continuous exposure to increasing doses of doxorubicin, cisplatin and 5-fluorouracil (FAP regimen)." | 3.79 | Association between reversal of multidrug resistance by methyl jasmonate and P-glycoprotein ATPase activity in hepatocellular carcinoma. ( Huang, FZ; Jiang, XZ; Liu, XY; Nie, WP; Wang, CF; Wang, YQ, 2013) |
| "A 65-year-old woman who had diffuse hepatocellular carcinoma(HCC)with tumor thrombus of right portalvein(Vp3) and lung metastases(Stage IVB)was treated by single-agent therapy with tegafur/uracil(UFT)." | 3.76 | [A case of hepatocellular carcinoma with portal vein thrombus(Vp3)and lung metastases(stage IVB),which responded completely to treatment with Tegafur/Uracil]. ( Adachi, K; Hiramatsu, S; Kurai, O; Miyano, M; Oka, H; Sasaki, E; Yamasaki, T, 2010) |
| "We herein report the complete remission of multiple recurrent hepatocellular carcinomas (HCCs) by the oral administration of tegafur/uracil (UFT) alone." | 3.75 | Complete remission of multiple recurrent hepatocellular carcinomas by oral administration of enteric-coated tegafur/uracil in a patient with huge hepatocellular carcinoma extending to the inferior vena cava after hepatic resection: analysis of mRNA expres ( Asakawa, M; Fujii, H; Kono, H; Matsuda, M; Shiba, S, 2009) |
| "The 5 fluorouracil hepato-arterial infusion (5-FU HAI) therapy has a good effect on the liver metastases of colorectal cancer." | 3.72 | [The 5-fluorouracil hepato-arterial infusion with oral UFT therapy for the hepatic and extra hepatic metastases of colorectal cancer]. ( Ebuchi, M; Hasegawa, K; Kato, K; Koide, A; Maruyama, M; Maruyama, S; Ohbu, M; Takashima, I, 2004) |
| "We report a patient with hepatocellular carcinoma (HCC) with intraperitoneal lymph node metastases in whom UFT (uracil + tegafur) was markedly effective." | 3.71 | [A patient with hepatocellular carcinoma with intraperitonial lymph node metastases in whom oral UFT treatment was markedly effective]. ( Baba, Y; Imamura, Y; Kubozono, O; Maenohara, S; Moriya, H; Ogura, Y; Tahara, K, 2002) |
| "We report a case of complete remission of multiple hepatocellular carcinomas after oral administration of enteric-coated tegafur/uracil." | 3.70 | Complete remission of multiple hepatocellular carcinomas associated with hepatitis C virus-related, decompensated liver cirrhosis by oral administration of enteric-coated tegafur/uracil. ( Asakura, H; Ebe, Y; Ichida, T; Ishikawa, T; Ishimoto, Y; Naito, M; Nomoto, M; Usuda, H; Yokoyama, J, 1999) |
| " He had nausea, vomiting and anorexia due to pyloric stenosis, and was treated with 600 mg of UFT E granules/day orally for 5 consecutive days followed by 2 drug-free days (weekly-5 method), and 2 mg of lentinan intravenously twice a week." | 3.70 | [A case of advanced gastric cancer (type 3) with pyloric stenosis, multiple liver and lymph node metastases responding to UFT-E granules and lentinan]. ( Kondo, M; Takahashi, S; Takemura, T; Yoshikawa, T, 2000) |
| "We report a case of advanced hepatocellular carcinoma (HCC), successfully treated by a combination therapy of alpha-interferon (IFN-alpha) and tegafur/uracil (UFT)." | 3.70 | Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of alpha-interferon and oral tegafur/uracil. ( Dono, K; Eguchi, H; Gotoh, M; Kishimoto, S; Miyamoto, A; Monden, M; Nagano, H; Nakamori, S; Sakon, M; Umeshita, K, 2000) |
| "This study was designed to examine the optimal regimen of 5-fluorouracil (5-FU), uracil and degradable starch microspheres (DSM) to prevent the hepatic metastasis of colorectal cancer." | 3.69 | Inhibitory effect of simultaneous intraportal administration of 5-fluorouracil, uracil and degradable starch microspheres on experimental hepatic micrometastasis, is of colon cancer. ( Fujii, K; Hanaue, H; Kurosawa, T; Mitomi, T; Nakasaki, H; Tajima, T; Yasuda, S, 1994) |
| "UFT was administered preoperatively in 20 cases of primary hepatocellular carcinoma, and tegafur, 5-fluorouracil (5-FU), uracil, total thymidylate synthase (TS) and free TS in blood and liver tissue were determined." | 3.67 | [Study on the pharmacokinetics of UFT in patients with hepatocellular carcinoma associated with cirrhosis]. ( Ito, Y; Matsuoka, S; Misawa, K; Nagafuchi, E; Nakajima, Y; Ogasawara, K; Sato, N; Uchino, J; Une, Y, 1989) |
| " In 22 resected patients with hepatocellular carcinoma (HCC), the concentrations of 5-fluorouracil (5-FU), tegafur and uracil were estimated in the serum, liver and cancer tissues after oral administration of UFT (tegafur, 300mg) before operation." | 3.67 | [5-Fluorouracil, tegafur, and uracil concentrations in serum and tissue of the patients with hepatocellular carcinoma after UFT administration]. ( Suenaga, M, 1987) |
| "A Phase II study of co-administration of uracil and tegafur (UFT) was performed in 32 patients with unresectable hepatocellular carcinoma." | 3.67 | Phase II study of co-administration of uracil and tegafur (UFT) in hepatocellular carcinoma. Tokyo Liver Cancer Chemotherapy Study Group. ( , 1985) |
| "Recurrence of hepatocellular carcinoma (HCC) after surgery is frequent, and is an important factor adversely influencing the long-term survival of patients." | 2.82 | Administration of adjuvant oral tegafur/uracil chemotherapy post hepatocellular carcinoma resection: A randomized controlled trial. ( Ishizuka, M; Iso, Y; Kato, M; Kubota, K; Nemoto, T; Shimoda, M; Tago, K, 2016) |
| "Patients with clinical stage II or III rectal cancer were treated with radiotherapy of 44 Gy in 22 fractions." | 2.79 | Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study. ( Chen, HC; Chen, HH; Chen, WT; Chien, CR; Hsiao, CF; Lee, HH; Lin, TC; Lin, TY; Liu, TW; Wang, LW, 2014) |
| "8% and grade 3 or higher adverse events occurred in 12." | 2.79 | A combination of oral uracil-tegafur plus leucovorin (UFT + LV) is a safe regimen for adjuvant chemotherapy after hepatectomy in patients with colorectal cancer: safety report of the UFT/LV study. ( Hasegawa, K; Ijichi, M; Kawasaki, S; Kokudo, N; Koyama, H; Makuuchi, M; Miyagawa, S; Oba, M; Saiura, A; Takayama, T; Teruya, M; Yamamoto, J; Yoshimi, F, 2014) |
| "More than two-thirds of patients with gastric cancer present with metastatic disease and their curative options are limited." | 2.73 | Phase II study of cisplatin, epirubicin, UFT, and leucovorin (PELUF) as first-line chemotherapy in metastatic gastric cancer. ( Baruch, NB; Biran, H; Dinerman, M; Idelevich, E; Karminsky, N; Katsenelson, RL; Man, S; Shani, A; Zvi, NB, 2007) |
| "From 2002 to 2007, a total of 10 consecutive patients with Stage IVA HCC accompanied by PVTT were studied prospectively to examine the efficacy of treatment by intra-arterial infusion of a chemotherapeutic agents consisting of etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil." | 2.73 | Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-arterial chemotherapy combining etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil: a p ( Imai, M; Ishikawa, T; Kamimura, H; Kamimura, T; Ohta, H; Seki, K; Togashi, T; Tsuchiya, A; Watanabe, K; Yoshida, T, 2007) |
| "Standard chemotherapy for advanced biliary tract cancer has not been established." | 2.72 | Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer. ( Funakoshi, A; Furuse, J; Horikawa, Y; Ikeda, M; Ishii, H; Mizuno, N; Morizane, C; Nagase, M; Nakachi, K; Okusaka, T; Ueno, H; Yamao, K, 2006) |
| "Frequent recurrence of hepatocellular carcinoma (HCC) after surgery remains a major clinical problem." | 2.72 | Uracil-tegafur as an adjuvant for hepatocellular carcinoma: a randomized trial. ( Hasegawa, K; Ijichi, M; Imamura, H; Kokudo, N; Makuuchi, M; Matsuyama, Y; Sano, K; Sugawara, Y; Takayama, T, 2006) |
| ") gemcitabine (GEM) at low dose plus oral chemotherapy with uracil-tegafur (UFT) and cyclophosphamide (CPA) in combination with radiotherapy (RT) against recurrent and advanced pancreatic cancers." | 2.71 | Phase II study on low dose gemcitabine plus oral chemotherapy with uracil-tegafur and cyclophosphamide in combination with radiotherapy against recurrent and advanced pancreatic cancer. ( Endo, S; Hashimoto, K; Higami, T; Itakura, M; Koike, M; Maruyama, R; Nio, Y; Tsuji, M; Yamaguchi, K; Yano, S, 2005) |
| " A phase II clinical trial of this combination using a continuous dosing schedule was carried out in patients with metastatic colorectal cancer." | 2.70 | Eastern Cooperative Oncology Group phase II trial (E4296) of oral 5-fluorouracil and eniluracil as a 28-day regimen in metastatic colorectal cancer. ( Benson, AB; Catalano, P; Cornfeld, MJ; Graham, DL; Huang, J; Marsh, JC; O'Dwyer, PJ, 2002) |
| "Only a minority of patients with hepatocellular carcinoma (HCC) may benefit from curative treatments, whereas there is no standard therapy for the remaining patients." | 2.70 | A phase II trial of oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma. ( Bruix, J; Castells, L; El-Hariry, I; Llovet, JM; Peachey, M; Ruff, P; Tassopoulos, N, 2001) |
| "Uracil-tegafur (UFT) has been reported to have a broad anti-tumor activity in a variety of malignancies including colorectal cancer and breast cancer." | 2.70 | Phase II study of uracil-tegafur in patients with metastatic pancreatic cancer. ( Ikeda, M; Kuriyama, H; Okada, S; Okusaka, T; Ueno, H, 2002) |
| "Twenty-two colorectal cancer patients (infusion group) in Dukes' C stage were given hepatic arterial infusion of 5-FU (500 mg/body for 1 hr per week, repeated 50 times) and peroral UFT-E (2." | 2.69 | [Clinical trial of prophylactic hepatic arterial chemotherapy for liver metastases in patients with Dukes' C colorectal cancer]. ( Fujioka, M; Idezuki, Y; Inokuma, S; Ishida, H; Kamano, T; Kishi, T; Kondo, K; Matsumoto, Y; Miura, T; Murata, N; Nakada, H; Odaka, A; Shimomura, K; Suzuki, T; Takeuchi, I; Yamada, H, 1999) |
| "Pharmacokinetic modulating chemotherapy (PMC) is a new therapeutic concept in combination with continuous 5-fluorouracil (5-FU) infusion and UFT." | 2.69 | Results of pharmacokinetic modulating chemotherapy in combination with hepatic arterial 5-fluorouracil infusion and oral UFT after resection of hepatic colorectal metastases. ( Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R, 2000) |
| "Patients with hepatocellular carcinoma (HCC) are highly compromised by failing liver function." | 2.68 | A pharmacological pilot study: application of an intermittent schedule of oral uracil and ftorafur (UFT) for hepatocellular carcinoma patients. ( Haneda, T; Kamiyama, T; Nakanishi, K; Nishibe, M; Shimamura, T; Uchino, J; Une, Y, 1996) |
| "UFT (tegafur and uracil) has been studied extensively in Japan, with documented efficacy in hepatobiliary and pancreatic cancer." | 2.68 | UFT plus leucovorin in advanced hepatobiliary tumors and pancreatic adenocarcinomas. ( Mani, S, 1997) |
| "Thirty-four patients with advanced gastric cancer were treated with combination chemotherapy employing Tegafur-Uracil (UFT), etoposide, Adriamycin, and Cisplatinum (CDDP) (UFT-EAP therapy)." | 2.67 | Combination chemotherapy with Tegafur. Uracil (UFT), etoposide, adriamycin and cisplatinum (UFT-EAP) for advanced gastric cancer. ( Chin, K; Hattori, T; Hayakawa, M; Maeda, H; Morise, K; Morooka, Y; Saito, H; Sugihara, M, 1994) |
| "Metastatic colorectal cancer has a poor prognosis, and the majority of patients are left with palliative measures." | 2.42 | Palliative treatment of patients with colorectal cancer. ( Glimelius, B, 2003) |
| "The preoperative diagnosis was giant hepatocellular carcinoma (HCC) of the right hepatic anterior region, and extended anterior segmentectomy of the liver was performed." | 2.42 | [Complete disappearance with oral UFT administration of recurrent hepatocellular carcinoma of the remnant liver and multiple lung metastasis after hepatic resection]. ( Hanazaki, K; Kawasaki, S; Kobayashi, A; Matsushita, A; Misawa, R; Miwa, S; Miyagawa, S; Nakagawa, K; Nakata, T; Noike, T; Nomura, K, 2003) |
| "Alogliptin is an anti-diabetic that may have effective anticancer properties against many types of malignancies." | 1.62 | Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis. ( Abd Elmaaboud, MA; Arab, HH; Kabel, AM, 2021) |
| "She died of a sigmoid cancer 32 months after UFT/LV initiation." | 1.51 | [A Case Report of a Patient Over 90 Years of Age with Liver Metastasis after Sigmoid Colectomy Controlled by a Combination Oral UFT/LV Chemotherapy Regimen]. ( Hosono, M; Ienaga, T; Iwabuchi, S; Kawasaki, K; Okazaki, T; Owada, Y; Tanaka, S, 2019) |
| " The Grade 3 or worst adverse event that was experienced was neutropenia." | 1.48 | [Safety and Efficacy of TAS-102 with Bevacizumab for the Treatment of Unresectable Metastatic Colorectal Cancer - A Case Report]. ( Arakawa, S; Asano, Y; Horiguchi, A; Imaeda, Y; Isetani, M; Ishihara, S; Ito, M; Ito, R; Kamio, K; Kawabe, N; Kawai, T; Nagata, H; Shimizu, K; Tomishige, H; Yasuoka, H, 2018) |
| "The possibility of interstitial pneumonitis should always be considered when a patient develops a fever and respiratory disorder during treatment containing TAS-102." | 1.48 | [A Case of Interstitial Pneumonitis Induced by TAS-102 for Liver and Lung Metastasis of Colorectal Cancer]. ( Hiramatsu, M; Imai, Y; Kobayashi, T; Kono, E; Sakane, J; Suzuki, Y; Tsunematsu, I, 2018) |
| "Tegafur-uracil has been reported to have only minor adverse effects and is associated with liver injury in 1." | 1.46 | Tegafur-uracil-induced rapid development of advanced hepatic fibrosis. ( Fujiya, M; Hasebe, T; Honda, S; Nakajima, S; Okumura, T; Sawada, K, 2017) |
| "At the age of 46, he was diagnosed with hepatocellular carcinoma with subsequent resection of the tumour in May 2015." | 1.46 | Successful twice interrupted therapy of HCV infection in patients with cirrhosis with hepatocellular carcinoma before and after liver transplantation. ( Rostkowska, K; Simon, K; Szymanek-Pasternak, A, 2017) |
| "Human hepatoma cells (HepG2) were exposed to a single dose of MCLR (1 μg/mL), graded doses of CYN (0." | 1.46 | Genotoxic potential of the binary mixture of cyanotoxins microcystin-LR and cylindrospermopsin. ( Cameán, AM; Filipič, M; Hercog, K; Jos, Á; Maisanaba, S; Žegura, B, 2017) |
| " Details of serious adverse events (SAEs) were recorded." | 1.46 | Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort. ( Albillos, A; Ampuero, J; Arenas, J; Bañares, R; Calleja, JL; Crespo, J; Diago, M; Fernandez, I; García-Eliz, M; García-Samaniego, J; Gea, F; Jorquera, F; Lens, S; Llaneras, J; Llerena, S; Mariño, Z; Morillas, RM; Muñoz, R; Navascues, CA; Pascasio, JM; Perelló, C; Rincón, D; Rodriguez, CF; Ruiz-Antorán, B; Sacristán, B; Serra, MA; Simon, MA; Torras, X; Turnes, J, 2017) |
| "Abdominoperineal resection+D3 of rectal cancer was performed, followed by chemotherapy with UFT for 28 days, and then partial resection of liver." | 1.37 | [A case of synchronous hepatic and multiple pulmonary metastases from rectal cancer responding completely to UFT therapy after resection of primary and hepatic lesions]. ( Doi, F; Ishikawa, N; Kohro, T; Kusumoto, C; Kusumoto, M; Matsumoto, T; Toyoda, S, 2011) |
| "Herein, we report a bladder cancer case with multiple metastases which were controlled by low-dose UFT." | 1.37 | [A case of marked efficacy of low-dose UFT against metastatic bladder cancer]. ( Arai, Y; Ito, A; Kuwahara, M; Nakano, O; Satoh, M, 2011) |
| "A69-year-old man was diagnosed with sigmoid colon cancer and underwent resection of the sigmoid colon." | 1.36 | [Multiple liver metastases due to sigmoid colon cancer successfully treated by degradable starch microspheres (DSM)-TAE, radiofrequency ablation therapy, and Uzel/UFT]. ( Higuchi, K; Ishikawa, T; Kamimura, T; Kubota, T; Ohta, H; Seki, K; Yoshida, T, 2010) |
| "We report a case of hepatocellular carcinoma (HCC) in association with autoimmune hepatitis (AIH)." | 1.36 | [A case of hepatocellular carcinoma with autoimmune hepatitis showing marked reduction of tumors by oral administration of UFT-E]. ( Aizawa, N; Enomoto, H; Hirota, S; Iijima, H; Ikeda, N; Imanishi, H; Ishii, A; Iwai, T; Iwata, Y; Nishiguchi, S; Saito, M; Sakai, Y; Shimomura, S; Takashima, T; Tanaka, H; Yamamoto, T; Yoh, K; Yoshikawa, S, 2010) |
| "Sigmoidectomy was performed for sigmoid colon cancer in January 2002." | 1.36 | [A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy]. ( Doki, Y; Hirose, H; Ikeda, M; Kim, HM; Miyoshi, N; Mizushima, T; Mori, M; Okano, M; Sekimoto, M; Takemasa, I; Yamamoto, H; Yamashita, S, 2010) |
| "We report a case of gastric cancer with simultaneous multiple liver metastasis that was successfully treated by paclitaxel and UFT-E." | 1.35 | [A case of multiple hepatic metastases of gastric cancer that showed complete regression by systemic chemotherapy using paclitaxel and UFT-E]. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Kikuchi, S; Kokuba, Y; Kubota, T; Nakanishi, M; Ochiai, T; Okamoto, K; Okamura, H; Otsuji, E; Sakakura, C; Sonoyama, T; Taniguchi, H, 2009) |
| "Primary liver cancer with lymph node metastasis was recognized as poor prognosis." | 1.35 | [A case report of combined hepatocellular-cholangiocarcinoma whose lymph node recurrence effectively treated with UFT]. ( Akagi, K; Dono, K; Fujita, J; Hata, T; Hayashi, S; Ikeda, K; Kagawa, Y; Kawanishi, K; Kitada, M; Munakata, K; Shimano, T; Shimizu, J; Takamoto, K; Watanabe, N; Yasumoto, T; Zenitani, M, 2009) |
| "A 82-year-old woman with gastric cancer underwent distal gastrectomy with level 2 lymph node dissection(M, Less, 2." | 1.35 | [A case of complete remission(CR)persisting from UFT-E in an old patient with liver metastasis of gastric cancer]. ( Aoki, K; Hirama, K; Kazunori Ikenaga, S; Maruyama, M; Matsumoto, R; Oguro, H; Sakamoto, Y; Sakuraba, H, 2008) |
| "Here, we report the case of a sigmoid colon cancer patient with initially unresectable hepatic metastases showing a prolonged survival (6." | 1.34 | [A long survival case of sigmoid colon cancer patient with initially unresectable hepatic metastases]. ( Gega, M; Hashimoto, A; Ikeuchi, H; Kuno, T; Noda, M; Oshima, T; Tanaka, K; Tsukamoto, K; Yagyuu, T; Yamamura, T; Yanagi, H; Yoshikawa, R, 2007) |
| "A distal gastrectomy for advanced gastric cancer with liver metastasis was performed on a 71-year-old male." | 1.34 | [A case of liver metastasis of gastric cancer undergoing non-curative operation responding completely to combination therapy of S-1 and CDDP]. ( Aoki, T; Mino, A; Murahashi, K; Nishino, K; Sowa, M; Tachimori, A; Takagaki, K, 2007) |
| " 5-FU serum concentrations were higher at night time and the peak concentration of 5-FU was obtained at 3 a." | 1.33 | [Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report]. ( Hatakeyama, K; Muneoka, K; Shirai, Y; Wakai, T; Yokoyama, N, 2005) |
| "The data on 307 patients with colorectal cancer at stage II or III, who underwent potentially curative resection with lymphadenectomy, were reviewed." | 1.33 | The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. ( Ikeda, S; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Ogo, S; Ohkita, A; Ozasa, H; Sasatomi, T; Shirouzu, K, 2006) |
| "A 54-year-old woman who had ascending colon cancer with multiple liver and lung metastases underwent rt." | 1.33 | [A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11]. ( Fujii, Y; Kobayashi, T; Kuga, T; Matsuoka, T; Morikage, N; Nakayama, T, 2005) |
| "A 65-year-old man was diagnosed as esophageal cancer with multiple liver metastases (S2 10 mm, S7 10 mm, S8 15 mm)." | 1.33 | [A 6-year-survival case of esophageal adenosquamous cancer with liver metastases cured by multidisciplinary therapy]. ( Doi, K; Furuhashi, S; Ishihara, A; Ishimoto, T; Kikuchi, N; Ogata, K; Ogawa, M; Ohchi, T, 2006) |
| "A 73-year-old man was admitted for sigmoid colon cancer with multiple hepatic metastases." | 1.33 | [A case of hepatic metastases of sigmoid colon cancer which completely responded to systemic l-leucovorin/5-FU therapy and oral LV/UFT combination therapy]. ( Ishigame, T; Ishii, Y; Okayama, H; Takahashi, M, 2006) |
| "The patient diagnosed as recurrent pancreatic cancer was treated with UFT combined gemcitabine (GEM) chemotherapy." | 1.33 | [A case of recurrent pancreatic cancer responding to TS-1 combined gemcitabine chemotherapy after UFT combined gemcitabine chemotherapy resulting progressive disease]. ( Kagaya, T; Kaneko, S; Kato, Y; Sunagozaka, H; Yamashita, T, 2006) |
| "We report a rare patient with a DPD deficiency." | 1.33 | [A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency]. ( Arai, K; Hashimoto, T; Hiruma, K; Iwasaki, Y; Matsumoto, H; Saze, Z; Takahashi, K; Yamaguchi, T; Yamashita, Y; Yasutome, M, 2006) |
| "We report a case of advanced hepatocellular carcinoma (HCC)." | 1.33 | [Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma providing a good QOL]. ( Amano, M; Fujita, M; Hayashida, H; Higaki, N; Nakagawa, S; Niinobu, T; Nishikawa, Y; Sakon, M; Yamashita, S, 2006) |
| " Pharmacokinetic modulating chemotherapy (PMC) was performed after the operation." | 1.32 | [A case of multiple liver metastases from colon cancer successfully treated with pharmacokinetic modulating chemotherapy]. ( Futamura, N; Matsutomo, M; Sakamoto, K; Tateyama, K; Yasumura, M, 2003) |
| "We report a rectal cancer case with liver and lung metastases treated successfully with this protocol." | 1.32 | [A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT]. ( Ebuchi, M; Hasegawa, K; Kato, K; Maruyama, M; Nagahama, T; Shinoura, H; Takashima, I, 2003) |
| "He then underwent excision of the brain metastases and consecutive radiation by X-knife." | 1.32 | [A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy]. ( Arai, K; Iwasaki, Y; Katayanagi, S; Matsumoto, H; Miyamoto, H; Takahashi, K; Yamaguchi, T, 2003) |
| "A 72-year-old man with common bile duct cancer was treated by pylorus preserving pancreatoduodenectomy with D3 lymph node dissection and preventive radiotherapy at hepaticojejunostomy." | 1.32 | [A case of liver metastatic recurrence of bile duct cancer completely responding to single drug, UFT, chemotherapy]. ( Hirano, T; Kitahara, K; Magata, S; Matsuyama, S; Miyazaki, K; Mori, M; Shimonishi, T, 2004) |
| " He was treated with pharmacokinetic modulating chemotherapy (PMC) and low-dose CPT-11." | 1.32 | [A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11]. ( Aihara, T; Fukuhara, A; Kouno, T; Murayama, M; Nakagawa, K; Nakamura, E; Niida, M; Nishimoto, Y; Nozaki, H; Syouda, S; Watanabe, Y; Yagyu, T; Yasuoka, H, 2004) |
| "We treated a patient with unresectable rectal cancer with multiple liver, pulmonary and lymph node metastases that responded remarkably to pharmacokinetic modulating chemotherapy (PMC)." | 1.31 | [A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy]. ( Chiba, M; Hayashi, K; Inaba, Y; Kamio, Y; Koyama, M; Ohe, S; Watabe, S, 2002) |
| " Administration of modified pharmacokinetic modulating chemotherapy (PMC) using Leucovorin (intravenous infusion of 5-FU, 600 mg/m2/24 hours; oral administration of UFT, Taiho Pharmaceutical Co." | 1.31 | [A case of multiple liver metastases from colon cancer successfully treated with modified pharmacokinetic modulating chemotherapy using Leucovorin]. ( Hatada, T; Inoue, Y; Kobayashi, M; Kusunoki, M; Miki, C; Ojima, E, 2002) |
| "Advanced unresectable hepatocellular carcinoma (HCC) was treated with modified pharmacokinetic modulation chemotherapy (PMC)." | 1.31 | [Modified pharmacokinetic modulation chemotherapy (PMC) with medication of UFT and intraarterial infusion of 5-FU for advanced unresectable HCC]. ( Ito, T; Kamachi, H; Kamiyama, T; Kondo, M; Kurauchi, N; Matsushita, M; Nakagawa, T; Nishikawa, M; Ogata, T; Todo, S, 2002) |
| "Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon." | 1.31 | Complete disappearance of recurrent hepatocellular carcinoma with peritoneal dissemination and splenic metastasis: a unique clinical course after surgery. ( Amano, J; Hanazaki, K; Koide, N; Matsunaga, Y; Shiohara, E; Terasaki, T, 2000) |
| "We report a case of advanced rectal cancer accompanied by unresectable liver metastasis in which remission has been achieved for 7 years." | 1.31 | [A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective]. ( Baba, H; Kikunaga, H; Matsudo, A; Miura, H; Morisue, A; Nakai, H; Osakabe, Y; Sotome, K; Takao, M, 2000) |
| "We encountered a case of unresectable colon cancer that disappeared following pharmacokinetic modulating chemotherapy (PMC)." | 1.31 | [A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)]. ( Asahara, T; Nakahara, H; Nakahara, M; Okajima, M; Yano, M, 2000) |
| " Intermittent hepatic arterial infusion of high-dose 5-FU was started on a weekly schedule and oral UFT was added as pharmacokinetic modulating chemotherapy 4 weeks after the initial chemotherapy." | 1.31 | [A successful case of preoperative intermittent hepatic arterial infusion of high-dose 5-FU and pharmacokinetic modulating chemotherapy against unresectable liver metastasis of colon cancer]. ( Hamazaki, K; Inagaki, M; Kawashima, T; Morichika, T; Sadamori, H; Shima, Y; Tanaka, N; Uetsuka, H; Yagi, T, 2000) |
| "For cases of liver metastasis from colon cancer that are non-resectable due to multiple liver metastases, other organ metastases (lung, bone, brain etc." | 1.31 | [Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11]. ( Kobayashi, A; Yamaguchi, M, 2000) |
| "A total of 18 patients (13: colon cancer, 5: gastric cancer) with multiple liver metastases (H3) underwent hepatic arterial infusion chemotherapy (HAI) using an implanted arterial port with portable syringe pumps in our outpatient clinic." | 1.31 | [Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases]. ( Fukunaga, M; Goda, F; Maeba, T; Maeta, H; Mihara, T; Mori, S; Ohkawa, M; Okada, H; Okano, K; Senda, S; Uchida, Y; Usuki, H; Wakabayashi, H, 2000) |
| "A 67-year-old female with rectal cancer and multiple liver metastases underwent low anterior resection by total mesorectal excision (TME), cholecystectomy and hepatic arterial cannulation in June 1995." | 1.31 | [Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)]. ( Kusunoki, M; Noda, M; Yamamura, T; Yanagi, H; Yoshikawa, R, 2001) |
| "Ultrasound and CT scan showed that the hepatocellular carcinoma and lung metastatic foci had disappeared completely." | 1.31 | [Complete response of a massive hepatocellular carcinoma with lung metastasis to UFT (DPD inhibitory fluoroprymidines: DIF)]. ( Haseme, E; Kikuchi, K; Ohnishi, Y; Shohkei, O, 2001) |
| "A 77-year-old man who had advanced gastric cancer with multiple liver metastases was treated by combined chemotherapy with 5-fluorouracil and low-dose cisplatin for 1 and half courses (1 course = 4 weeks)." | 1.31 | [A case of advanced gastric cancer complicated with liver metastases responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin, with UFT and low-dose cisplatin for maintenance on an outpatient basis]. ( Ikeda, S; Iwamoto, M; Nagata, S; Niiya, F; Shirouzu, K, 2001) |
| "Human colon cancer cells (KM12SM) were injected into the cecal wall of the nude rats." | 1.31 | [Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats]. ( Akagi, Y; Kobayashi, H; Matono, K; Miyagi, Y; Nakagawa, M; Nozoe, Y; Ogata, Y; Sasatomi, T; Shirouzu, K, 2001) |
| " He was treated postoperatively with arterial infusion pharmacokinetic modulating chemotherapy (PMC) and venous infusion CPT-11 (modified PMC)." | 1.31 | [A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy]. ( Dan, T; Kitayama, Y; Kosaka, H; Maeda, S; Matsusaka, S; Okada, T; Tanabe, H; Yamasaki, H, 2002) |
| "A 56-year-old male had suffered from hepatocellular carcinoma treated by operation, PHoT and TAE since 1994." | 1.30 | [A case of hepatocellular carcinoma with reduction of primary tumor and disappearance of multiple lung metastasis]. ( Ando, A; Asano, N; Bamba, T; Fujiyama, Y; Fukano, M; Inoue, T; Ito, A; Koyama, S; Kubo, M; Sasaki, M; Sato, J; Tsujikawa, T; Yoshioka, U, 1998) |
| "Multiple liver and lung metastasis of breast cancer were diagnosed because of high CA 15/3 serum levels and normal gastrointestinal study." | 1.30 | [Effective chemo-endocrine combination therapy for obstructive-jaundice caused by multiple liver metastasis of recurrent breast cancer--a case report]. ( Hoshino, K; Ikeda, H; Koyama, T; Morishita, Y; Nakamura, M, 1999) |
| "Treatment of hepatocellular carcinoma with bone metastasis is often ineffective, but this is a rare case showing the clinical effectiveness of oral administration of UFT." | 1.29 | [A case of hepatocellular carcinoma with bone metastasis responding to oral administration of UFT]. ( Chao, C; Imada, T; Maehara, T; Matsumoto, A; Miyazaki, T; Morinaga, S; Takehana, T, 1995) |
| "Macroscopically it was gastric cancer with P0H3N1T3M0, Stage IV b, histologically small cell carcinoma, intermed, INF gamma, ss, ly1, v3, n1(+), ow(-), aw(-)." | 1.29 | [A case of small cell carcinoma of the stomach with multiple liver metastases]. ( Ishizawa, S; Masuyama, K; Oonishi, Y; Sawataishi, M; Suzuki, S; Wakaki, K; Yamazaki, K, 1994) |
| "A 65-year-old male with hepatocellular carcinoma was admitted to our hospital." | 1.29 | [A case of hepatocellular carcinoma whose lung metastases and tumor emboli in the inferior vena cava disappeared by oral administration of UFT]. ( Fujiyama, S; Hashiguchi, O; Hayashida, T; Ikebe, M; Noumaru, S; Sato, K; Sato, T; Shibata, J, 1994) |
| "A 74-year-old man was diagnosed as hepatocellular carcinoma (HCC) in the area of S6-7 with tumor thrombus continuously developed from hepatic vein to inferior vena cava (IVC)." | 1.29 | [Vanishing tumor thrombus in IVC after oral administration of UFT and TAE in a patient with HCC; a case report]. ( Ito, T; Koreeda, C; Naitoh, Y; Nakagawa, T; Okuno, H; Seki, T; Shiro, T; Tagawa, Y; Wakabayashi, M; Yamamura, H, 1993) |
| "We found a hepatocellular carcinoma, of about 9 cm in diameter in her right liver lobe." | 1.29 | [A case of giant hepatocellular carcinoma effectively treated by UFT]. ( Hino, F; Urabe, T, 1993) |
| "A 79-year-old female with hepatocellular carcinoma with portal invasion and right adrenal gland metastasis was treated by low dose UFT (200 mg/day)." | 1.29 | [A case of hepatocellular carcinoma with portal invasion and right adrenal gland metastasis showing marked contraction of primary tumor and metastasis with treated by UFT alone]. ( Itoh, Y; Ohkawa, S; Tamai, S; Tarao, K, 1994) |
| "Effects of 5-fluorouracil (5-FU) and UFT on an experimental liver metastasis model were compared at equi-effective dosage levels against subcutaneous tumor of mouse colon 26." | 1.29 | Effect of 5-fluorouracil and UFT on experimental liver metastasis model of colorectal cancer using mouse colon 26 cells. ( Kosaki, G; Kurihara, M; Tominaga, T; Yoshida, Y, 1993) |
| "A 77-year-old male with liver cirrhosis was admitted to our hospital for further examination and treatment of liver tumor." | 1.29 | [A case of hepatocellular carcinoma responding to oral administration of UFT]. ( Matsumoto, K; Onodera, H; Otawa, K; Sato, T; Ukai, K, 1996) |
| "At the same time, malignant lymphoma of the liver and several bones were disclosed, but these tumors had become remarkably smaller after chemotherapy, radiotherapy and transcatheter hepatic arterial chemoembolization." | 1.29 | [A case of early gastric cancer transformed from adenoma by chemotherapy and radiotherapy]. ( Fujioka, S; Kato, K; Tomono, H, 1996) |
| "A 79-year-old man having advanced gastric cancer with liver metastasis was treated by gastric dissection and gastro-jejunostomy." | 1.29 | [Successful UFT-E granule and 5-FUCDDP combination therapy for an unresectable advanced gastric cancer complicated with liver metastasis]. ( Hyakuna, Y; Kushibiki, K; Matsuoka, H; Shimada, M; Yokomichi, H, 1996) |
| " Pharmacokinetic examination after intravenous injection of low-dose MMC (0." | 1.29 | A case of advanced gastric cancer complicated by severe toxicity induced by a combination of tegafur, uracil and mitomycin C, and associated with abnormal pharmacokinetics. ( Boku, N; Ishii, H; Kaneko, K; Kusada, O; Muro, K; Muto, M; Ohkuwa, M; Ohtsu, A; Sasaki, Y; Tajiri, H; Yoshida, S, 1996) |
| "A case of gastric cancer with liver metastasis who responded well to low-dose PMUE (CDDP, MMC, UFT, etoposide) therapy is reported." | 1.29 | [A case of advanced gastric cancer showing complete disappearance of cancer cells in multiple liver metastases due to low-dose PMUE therapy]. ( Hirono, T; Hirosawa, H; Izumi, R; Kadoya, N; Konishi, I; Ohta, N; Saito, K; Ueda, N; Yoshimitsu, Y, 1996) |
| "Often operations for gastric cancer accompanied with multiple liver metastasis meet with little success, and almost no case of prolonged survival has been reported." | 1.28 | [A case of gastric cancer with multiple liver metastases effectively treated with PMUE (CDDP, MMC, UFT, etoposide) hepatic arterial chemotherapy]. ( Fukushima, W; Hirosawa, H; Kadoya, N; Konishi, K; Kuroda, Y; Sahara, H; Saitoh, F; Taniya, T; Tsuji, M; Yabushita, K, 1992) |
| "A 74-year-old man with advanced gastric cancer of Borrmann type III and liver metastasis was treated by combined administration of UFT (400 mg/day, p." | 1.28 | [A case of advanced gastric cancer with liver metastasis completely responding to a combined immunochemotherapy with UFT, mitomycin C and lentinan]. ( Hatayama, H; Kitamura, H; Mashiko, H; Satoh, J, 1992) |
| "Etoposide was administered orally at 25-50 mg/day to the gastric cancer patient with liver metastasis." | 1.28 | [A resected case of advanced gastric cancer with complete remission of liver metastasis by chronic daily administration of oral etoposide and UFT]. ( Bandou, H; Kobayashi, T; Mura, T; Nomura, T; Watanabe, K, 1992) |
| "injection against mouse colon cancer, colon 26." | 1.28 | [Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis]. ( Fujimaki, M; Kurokawa, M; Kuroki, Y; Ochiai, H; Okamoto, M; Tazawa, K; Yamashita, I, 1991) |
| "Thermochemotherapy was performed on gastric cancer cases of hepato-metastasis." | 1.28 | [Clinical experiences with hyperthermochemotherapy of hepatic metastasis from gastric cancer]. ( Fujimura, T; Fushida, S; Kamata, T; Matuki, N; Matumoto, H; Sawa, T; Takegawa, S; Tsugawa, K; Urade, M; Yonemura, Y, 1991) |
| "Because the subjects studied were gastric cancer cases exceeding H2, the present investigation resulted in the increase of metastatic liver lesions, a problem to be studied in future." | 1.28 | [CDDP-ip PMUE therapy in gastric cancer cases with liver metastasis]. ( Hasegawa, Y; Honnma, S; Nakashima, Y; Takanashi, K; Yajima, K, 1991) |
| "5-FU concentration in liver cancer lesion was 0." | 1.28 | [Tissue UFT distribution and histological changes following UFT administration in metastatic liver cancer cases]. ( Amemiya, A; Emoto, T; Fujii, M; Han, N; Itou, A; Iwasaki, T; Tsujimura, T; Yoshikawa, K, 1990) |
| "These two cases showed no recurrent liver cancers." | 1.28 | [Results of prophylactic intra-arterial infusion chemotherapy after hepatic resection in colorectal metastases]. ( Houjo, K; Kawano, N; Moriya, Y; Sugihara, K, 1990) |
| "In 55 hepatocellular carcinoma patients treated with transcatheter arterial embolization or one shot therapy, the prognosis of patients treated with UFT (group A; n = 23) were historically compared with those of patients treated without UFT (group B; n=32)." | 1.28 | [Therapy of hepatocellular carcinoma with UFT--clinical evaluation of its effect in the combination therapy with transcatheter arterial embolization or one shot therapy]. ( Hayashi, K; Ishikawa, T; Ishinoda, Y; Iwaki, Y; Kisanuki, H; Kitamura, T; Maruyama, T; Nakamura, H; Okamoto, T; Shigehira, M, 1990) |
| "One year after total gastrectomy due to gastric cancer, the 50-year-old male patient underwent lateral segmentectomy, since metastatic foci occurred in the outer region of the liver." | 1.28 | [A case of biliary tract obstruction due to metastatic hepatic cancer, in which topical injection of CDDP and ADM into PTCD with concomitant use of UFT resulting in partial reopening of biliary tract]. ( Hayashi, T; Kitagawa, S; Nakagawa, M; Yamada, T, 1989) |
| "Primary hepatocellular carcinoma complicated by compensatory cirrhosis accompanying pulmonary metastasis was diagnosed from blood biochemistry tests, a high AFP value (390,000 ng/ml) and angiogram findings." | 1.27 | [Almost complete disappearance of metastatic pulmonary tumor and reduction of the main hepatic mass in a case of hepatocellular carcinoma treated with UFT]. ( Hayashi, K; Hidaka, Y; Kitamura, T; Maruyama, T; Nakamura, H; Nakatsuru, K; Shigehira, M; Tsuda, K, 1987) |
| "A diagnosis of hepatocellular carcinoma with extrahepatic portal venous obstruction due to tumor invasion was made." | 1.27 | [A case of hepatocellular carcinoma with extrahepatic portal vein obstruction due to tumor invasion, responsive to oral administration of UFT]. ( Kuroda, K; Maeda, S; Nagase, T; Nakagawa, C; Nakanishi, T; Nishikawa, M; Tokunaga, K, 1987) |
| "He was diagnosed as having primary hepatocellular carcinoma with bone metastasis by his high titer (111,683 ng/ml) of serum alpha-fetoprotein, computed tomography and abdominal angiography, and so UFT therapy, 400 mg daily, was instituted." | 1.27 | [A case of hepatocellular carcinoma with bone metastasis which responded to oral administration of UFT]. ( Imai, Y; Inada, M; Inui, Y; Kawata, S; Matsuda, Y; Minami, Y; Miyoshi, S; Noda, S; Saito, R; Tamura, S, 1987) |
| " the same therapy in combination with UFT as a maintenance therapy (group B; 8 patients)." | 1.27 | [Clinical evaluation of MMC-mc-chemoembolization therapy and its combination with UFT in hepatocellular carcinoma]. ( Matsuo, SK; Ohmura, K; Ohtsuka, Y; Suzuki, M, 1987) |
| "Preoperative total doses of UFT for gastric cancer were 3." | 1.27 | [Effects of preoperative administration of UFT in gastrointestinal cancer]. ( Kagaya, H; Matsuoka, S; Miyata, S; Nagabuchi, E; Sato, Y; Uchino, J; Une, Y; Yakura, Y, 1986) |
| "A case of relapsed gastric cancer postoperatively presenting obstructive jaundice due to metastases in the hepatic portal and periaortic lymph nodes and multiple lung metastases was given OK-432 continuously i." | 1.27 | [A case of relapsed gastric cancer treated successfully by chemotherapy--lung metastasis and relapsed cancer in the hepatic portal system]. ( Kawahara, M; Matsuo, T; Nagamatsu, Y; Nakarai, I; Shinoda, A, 1986) |
| "Two patients who had advanced gastric cancer and metastatic liver tumors were treated with a combined chemotherapy using UFT and mitomycin C." | 1.27 | [A combined chemotherapy with UFT and mitomycin C in advanced gastric cancer; report of 2 cases]. ( Hanawa, S; Hara, S; Joya, K; Nakata, K; Sato, K; Shigemitsu, M, 1985) |
| "Fifteen cases with advanced cancer were treated with UFD-1 (mixture of FD-1 and uracil under molar ratio of 1: 20) in a daily dose of 300 mg of FD-1." | 1.26 | [Clinical experiences with UFD-1]. ( Furue, H, 1982) |
| "The metabolic incorporation by tumors of this DNA-precursor indicates a potential value of this radiocompound for their detection, differentiation and follow-up of their evolution after therapy." | 1.26 | Radioactive nucleic acids-precursors: their potential value as tumor-localizing agents. ( Anghileri, LJ; Heidbreder, M; Mathes, R, 1977) |
| "Furthermore, Ehrlich ascites tumor cells indicating a high incorporation activity was also high in activities of both phosphorylase and kinase for uridine, while Rhodamine sarcoma as a representative having a low incorporation activity was considerably low in these two enzymic activities." | 1.26 | Incorporation characteristics of uracil, uridine, and orotic acid into ribonucleic acid of neoplastic cells. ( Tamemasa, O; Tezuka, M, 1977) |
| "Zajdela ascitic hepatoma cells are shown to take up pyrimidine bases at much lower rates than obtained in slices from normal rat liver." | 1.25 | Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells. ( Bhargava, PM; Bornecque, CA; Szafarz, D; Zajdela, F, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (19.87) | 18.7374 |
| 1990's | 63 (20.52) | 18.2507 |
| 2000's | 117 (38.11) | 29.6817 |
| 2010's | 58 (18.89) | 24.3611 |
| 2020's | 8 (2.61) | 2.80 |
| Authors | Studies |
|---|---|
| Sousa, MJ | 1 |
| Gomes, I | 1 |
| Pereira, TC | 1 |
| Magalhães, J | 1 |
| Basto, R | 1 |
| Paulo, J | 1 |
| Jacinto, P | 1 |
| Bonito, N | 1 |
| Sousa, G | 1 |
| Xu, M | 1 |
| Liu, Y | 1 |
| Wan, HL | 1 |
| Wong, AM | 1 |
| Ding, X | 1 |
| You, W | 1 |
| Lo, WS | 1 |
| Ng, KK | 1 |
| Wong, N | 1 |
| Fidelman, N | 2 |
| Atreya, CE | 2 |
| Griffith, M | 2 |
| Milloy, MA | 2 |
| Carnevale, J | 2 |
| Cinar, P | 2 |
| Venook, AP | 2 |
| Van Loon, K | 2 |
| Poordad, F | 1 |
| Castro, RE | 1 |
| Asatryan, A | 1 |
| Aguilar, H | 1 |
| Cacoub, P | 1 |
| Dieterich, D | 1 |
| Marinho, RT | 1 |
| Carvalho, A | 1 |
| Siddique, A | 1 |
| Hu, YB | 1 |
| Charafeddine, M | 1 |
| Bondin, M | 1 |
| Khan, N | 1 |
| Cohen, DE | 1 |
| Felizarta, F | 1 |
| Owada, Y | 2 |
| Kawasaki, K | 1 |
| Tanaka, S | 1 |
| Iwabuchi, S | 1 |
| Hosono, M | 1 |
| Okazaki, T | 1 |
| Ienaga, T | 1 |
| Hercog, K | 2 |
| Štampar, M | 1 |
| Štern, A | 1 |
| Filipič, M | 2 |
| Žegura, B | 2 |
| Shiraiwa, K | 1 |
| Suzuki, Y | 3 |
| Uchida, H | 1 |
| Iwashita, Y | 1 |
| Tanaka, R | 1 |
| Iwao, M | 1 |
| Tada, K | 2 |
| Hirashita, T | 1 |
| Masuda, T | 1 |
| Endo, Y | 3 |
| Inomata, M | 1 |
| Itoh, H | 1 |
| Kabel, AM | 1 |
| Arab, HH | 1 |
| Abd Elmaaboud, MA | 1 |
| Suenaga, M | 2 |
| Schirripa, M | 1 |
| Cao, S | 1 |
| Zhang, W | 1 |
| Yang, D | 1 |
| Murgioni, S | 1 |
| Rossini, D | 1 |
| Marmorino, F | 1 |
| Mennitto, A | 1 |
| Ning, Y | 1 |
| Okazaki, S | 2 |
| Berger, MD | 1 |
| Miyamoto, Y | 2 |
| Gopez, R | 1 |
| Barzi, A | 2 |
| Yamaguchi, T | 6 |
| Loupakis, F | 1 |
| Lenz, HJ | 1 |
| Honda, S | 3 |
| Sawada, K | 1 |
| Hasebe, T | 1 |
| Nakajima, S | 1 |
| Fujiya, M | 1 |
| Okumura, T | 1 |
| Moriwaki, T | 3 |
| Fukuoka, S | 2 |
| Taniguchi, H | 3 |
| Takashima, A | 2 |
| Kumekawa, Y | 2 |
| Kajiwara, T | 2 |
| Yamazaki, K | 5 |
| Esaki, T | 3 |
| Makiyama, C | 1 |
| Denda, T | 3 |
| Satake, H | 3 |
| Suto, T | 2 |
| Sugimoto, N | 3 |
| Enomoto, M | 2 |
| Ishikawa, T | 11 |
| Kashiwada, T | 2 |
| Sugiyama, M | 1 |
| Komatsu, Y | 3 |
| Okuyama, H | 2 |
| Baba, E | 2 |
| Sakai, D | 2 |
| Watanabe, T | 3 |
| Tamura, T | 2 |
| Yamashita, K | 3 |
| Gosho, M | 1 |
| Shimada, Y | 3 |
| Szymanek-Pasternak, A | 1 |
| Rostkowska, K | 1 |
| Simon, K | 2 |
| Maisanaba, S | 1 |
| Jos, Á | 1 |
| Cameán, AM | 1 |
| Jacobs, BAW | 1 |
| Snoeren, N | 1 |
| Samim, M | 1 |
| Rosing, H | 1 |
| de Vries, N | 1 |
| Deenen, MJ | 1 |
| Beijnen, JH | 1 |
| Schellens, JHM | 1 |
| Koopman, M | 1 |
| van Hillegersberg, R | 1 |
| Arakawa, S | 1 |
| Horiguchi, A | 1 |
| Tomishige, H | 1 |
| Kawabe, N | 1 |
| Nagata, H | 2 |
| Ishihara, S | 2 |
| Ito, M | 3 |
| Asano, Y | 1 |
| Ito, R | 1 |
| Isetani, M | 1 |
| Shimizu, K | 1 |
| Kamio, K | 1 |
| Kawai, T | 1 |
| Yasuoka, H | 2 |
| Imaeda, Y | 1 |
| Flisiak, R | 1 |
| Janczewska, E | 1 |
| Łucejko, M | 1 |
| Karpińska, E | 1 |
| Zarębska-Michaluk, D | 1 |
| Nazzal, K | 1 |
| Bolewska, B | 1 |
| Białkowska, J | 1 |
| Berak, H | 1 |
| Fleischer-Stępniewska, K | 1 |
| Tomasiewicz, K | 1 |
| Karwowska, K | 1 |
| Piekarska, A | 1 |
| Tronina, O | 1 |
| Tuchendler, E | 1 |
| Garlicki, A | 1 |
| Revuelta-Herrero, JL | 1 |
| Giménez-Manzorro, A | 1 |
| Matilla-Peña, A | 1 |
| Herranz-Alonso, A | 1 |
| Sanjurjo-Sáez, M | 1 |
| Unseld, M | 1 |
| Drimmel, M | 1 |
| Siebenhüner, A | 1 |
| Gleiss, A | 1 |
| Bianconi, D | 1 |
| Kieler, M | 1 |
| Scheithauer, W | 1 |
| Winder, T | 1 |
| Prager, GW | 1 |
| Tsuchihashi, K | 1 |
| Makiyama, A | 1 |
| Katsumata, K | 1 |
| Oki, E | 1 |
| Ueno, H | 4 |
| Kishimoto, J | 1 |
| Yoshino, T | 1 |
| Shinozaki, E | 1 |
| Nishina, T | 1 |
| Baba, H | 3 |
| Tsuji, A | 1 |
| Tsuji, Y | 2 |
| Yamaguchi, K | 2 |
| Muro, K | 2 |
| Takayama, T | 4 |
| Hamamoto, Y | 1 |
| Goto, M | 1 |
| Nakayama, N | 1 |
| Fujii, H | 3 |
| Tanase, T | 1 |
| Ohtsu, A | 2 |
| Cho, SK | 1 |
| Hay, JW | 1 |
| Kono, E | 1 |
| Hiramatsu, M | 1 |
| Kobayashi, T | 3 |
| Tsunematsu, I | 1 |
| Imai, Y | 2 |
| Sakane, J | 1 |
| Miyata, T | 1 |
| Beppu, T | 1 |
| Imamura, YU | 1 |
| Hayashi, H | 2 |
| Imai, K | 1 |
| Chikamoto, A | 1 |
| Yamashita, YI | 1 |
| Fukubayashi, K | 1 |
| Ishiko, T | 1 |
| Preda, CM | 1 |
| Baicus, C | 1 |
| Sandra, I | 1 |
| Oproiu, A | 1 |
| Manuc, T | 1 |
| Constantinescu, I | 1 |
| Gavrila, D | 1 |
| Diculescu, M | 1 |
| Dumitru, R | 1 |
| Vasilescu, C | 1 |
| Tieranu, C | 1 |
| Istratescu, D | 1 |
| Voiosu, T | 1 |
| Manuc, M | 1 |
| Fushiya, N | 1 |
| Takagi, I | 1 |
| Nishino, H | 1 |
| Akizuki, S | 1 |
| Ohnishi, A | 1 |
| Wang, CF | 1 |
| Wang, YQ | 1 |
| Huang, FZ | 1 |
| Nie, WP | 1 |
| Liu, XY | 1 |
| Jiang, XZ | 1 |
| Wang, YC | 1 |
| Lin, WL | 1 |
| Lin, YJ | 1 |
| Tang, FY | 1 |
| Chen, YM | 1 |
| Chiang, EP | 1 |
| Tanabe, K | 1 |
| Taura, K | 1 |
| Hatano, E | 2 |
| Koyama, Y | 2 |
| Takada, Y | 2 |
| Uemoto, S | 1 |
| Wang, LW | 1 |
| Hsiao, CF | 1 |
| Chen, WT | 1 |
| Lee, HH | 1 |
| Lin, TC | 1 |
| Chen, HC | 1 |
| Chen, HH | 1 |
| Chien, CR | 1 |
| Lin, TY | 1 |
| Liu, TW | 1 |
| Saiura, A | 2 |
| Yamamoto, J | 2 |
| Hasegawa, K | 6 |
| Oba, M | 2 |
| Miyagawa, S | 3 |
| Ijichi, M | 3 |
| Teruya, M | 2 |
| Yoshimi, F | 2 |
| Kawasaki, S | 3 |
| Koyama, H | 3 |
| Makuuchi, M | 3 |
| Kokudo, N | 4 |
| Gamal, N | 1 |
| Vitale, G | 1 |
| Andreone, P | 1 |
| Horváth, G | 1 |
| Halász, T | 1 |
| Makara, M | 1 |
| Hunyady, B | 1 |
| Ishizuka, M | 1 |
| Kubota, K | 1 |
| Nemoto, T | 2 |
| Shimoda, M | 1 |
| Kato, M | 2 |
| Iso, Y | 1 |
| Tago, K | 1 |
| Krastev, Z | 1 |
| Jelev, D | 1 |
| Antonov, K | 1 |
| Petkova, T | 1 |
| Atanasova, E | 1 |
| Zheleva, N | 1 |
| Tomov, B | 1 |
| Boyanova, Y | 1 |
| Mateva, L | 1 |
| Saab, S | 2 |
| Parisé, H | 2 |
| Virabhak, S | 2 |
| Wang, A | 2 |
| Marx, SE | 1 |
| Sanchez Gonzalez, Y | 1 |
| Misurski, D | 2 |
| Johnson, S | 2 |
| Gonzalez, YS | 1 |
| Juday, T | 1 |
| Takahashi, M | 3 |
| Mizunuma, N | 1 |
| Matsuyama, Y | 2 |
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| Noura, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study of Sorafenib Plus Tegafur/Uracil for the Treatment of Advanced or Metastatic Hepatocellular Carcinoma[NCT00464919] | Phase 2 | 50 participants (Anticipated) | Interventional | 2007-04-30 | Completed | ||
| Efficacy and Safety of Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinoma[NCT04059562] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-10-28 | Active, not recruiting | ||
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 reviews available for uracil and Liver Neoplasms
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
[Complete remission of hepatocellular carcinoma with multiple lung metastases by oral administration of tegafur/uracil].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 2013 |
ABT-450: a novel agent for the treatment of CHC genotype 1: focus on treatment-experienced patients.
Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Clinical Trials, | 2015 |
[New era in the treatment of chronic hepatitis C - novel direct acting antivirals].
Topics: 2-Naphthylamine; Administration, Oral; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Clini | 2015 |
Advances in the treatment of metastatic colorectal cancer.
Topics: Administration, Oral; Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cancer Vaccines; | 2001 |
Palliative treatment of patients with colorectal cancer.
Topics: Antimetabolites, Antineoplastic; Camptothecin; Colorectal Neoplasms; Disease Progression; Enzyme Inh | 2003 |
[Complete disappearance with oral UFT administration of recurrent hepatocellular carcinoma of the remnant liver and multiple lung metastasis after hepatic resection].
Topics: Administration, Oral; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers | 2003 |
[Chemotherapy for colorectal carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administrat | 2003 |
[Recent progress in chemotherapy for hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; C | 2004 |
Chemotherapy with enteric-coated tegafur/uracil for advanced hepatocellular carcinoma.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Humans; Liver Neop | 2008 |
Intraarterial infusion chemotherapy for unresectable hepatic metastases from colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Hepatic Artery; | 1996 |
[A noteworthy case of postoperative liver metastasis from gastric cancer which responded well to UFT therapy].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Gastrect | 2000 |
Nonsurgical treatment of hepatocellular carcinoma.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Capecitabine; Carcinoma, Hepatocellular; Chemoemboli | 2001 |
[A case of liver metastasis of gastric cancer which was made resectable by hypertheromo-chemo-radiotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; Hepate | 1989 |
Notes on some peculiarities of enzymic processes in malignant tumours and tissues of the host.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cholesterol; DNA, Neoplasm; | 1972 |
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Divisi | 1970 |
[Recent aspects of antiviral therapy].
Topics: Animals; Antibody Formation; Cattle; Chick Embryo; Chickens; Child; Herpes Zoster Ophthalmicus; Huma | 1971 |
49 trials available for uracil and Liver Neoplasms
| Article | Year |
|---|---|
Phase I prospective trial of TAS-102 (trifluridine and tipiracil) and radioembolization with
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fema | 2022 |
Phase I prospective trial of TAS-102 (trifluridine and tipiracil) and radioembolization with
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fema | 2022 |
Phase I prospective trial of TAS-102 (trifluridine and tipiracil) and radioembolization with
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fema | 2022 |
Phase I prospective trial of TAS-102 (trifluridine and tipiracil) and radioembolization with
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Fema | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Long-term safety and efficacy results in hepatitis C virus genotype 1-infected patients receiving ombitasvir/paritaprevir/ritonavir + dasabuvir ± ribavirin in the TOPAZ-I and TOPAZ-II trials.
Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, | 2020 |
The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto | 2018 |
Cost-effectiveness Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer in the United States.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cost-Benefit Analysis; Double- | 2018 |
Celecoxib plus chemoradiotherapy for locally advanced rectal cancer: a phase II TCOG study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Chemoradioth | 2014 |
A combination of oral uracil-tegafur plus leucovorin (UFT + LV) is a safe regimen for adjuvant chemotherapy after hepatectomy in patients with colorectal cancer: safety report of the UFT/LV study.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2014 |
Administration of adjuvant oral tegafur/uracil chemotherapy post hepatocellular carcinoma resection: A randomized controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemot | 2016 |
Adjuvant Oral Uracil-Tegafur with Leucovorin for Colorectal Cancer Liver Metastases: A Randomized Controlled Trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; | 2016 |
Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dih | 2009 |
Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Benzenesul | 2010 |
Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dis | 2011 |
A phase I/II study of combined chemotherapy with mitoxantrone and uracil/tegafur for advanced hepatocellular carcinoma.
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carci | 2011 |
Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplast | 2011 |
Final results of a prematurely discontinued Phase 1/2 study of eniluracil with escalating doses of 5-fluorouracil administered orally in patients with advanced hepatocellular carcinoma.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Asian People; Carcinoma, Hepat | 2011 |
Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study.
Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Antineoplastic Combined Chemotherap | 2012 |
Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Colorectal Neoplasms; | 2013 |
Eastern Cooperative Oncology Group phase II trial (E4296) of oral 5-fluorouracil and eniluracil as a 28-day regimen in metastatic colorectal cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2002 |
[Hepatic recurrence after prophylactic hepatic arterial infusion of 5-fluorouracil for Dukes' C colorectal cancer--correlation with the expression of dihydropyrimidine dehydrogenase in the primary tumor].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2002 |
Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch | 2003 |
[Clinical usefulness of UFT and cyclophosphamide as salvage chemotherapy for patients with metastatic breast cancer].
Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; | 2004 |
[Pharmacokinetic modulating chemotherapy highly effective for colorectal carcinoma metastases to multiple organs].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chronothe | 2005 |
Phase II study on low dose gemcitabine plus oral chemotherapy with uracil-tegafur and cyclophosphamide in combination with radiotherapy against recurrent and advanced pancreatic cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 2005 |
Phase II study with a combination of epirubicin, cisplatin, UFT, and leucovorin in advanced hepatocellular carcinoma.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antidotes; Antineoplastic Agents; Antineoplastic Combined | 2006 |
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug A | 2005 |
Early phase II study of uracil-tegafur plus doxorubicin in patients with unresectable advanced biliary tract cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2006 |
Uracil-tegafur as an adjuvant for hepatocellular carcinoma: a randomized trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemotherapy | 2006 |
Phase II study of cisplatin, epirubicin, UFT, and leucovorin (PELUF) as first-line chemotherapy in metastatic gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplat | 2007 |
Improved survival for hepatocellular carcinoma with portal vein tumor thrombosis treated by intra-arterial chemotherapy combining etoposide, carboplatin, epirubicin and pharmacokinetic modulating chemotherapy by 5-FU and enteric-coated tegafur/uracil: a p
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc | 2007 |
A phase II study of tegafur plus uracil or tegafur alone for the treatment of advanced hepatocellular carcinoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female | 2008 |
Adjuvant chemotherapy with tegafur/uracil administration after transcatheter arterial chemoembolization for advanced hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Combined Mo | 2008 |
A prospective randomized evaluation of a compound of tegafur and uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Combinations; Embolization, The | 1995 |
[The significance of portal infusion chemotherapy for prevention of recurrence in residual liver after hepatectomy for metastases from colorectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; He | 1994 |
Combination chemotherapy with Tegafur. Uracil (UFT), etoposide, adriamycin and cisplatinum (UFT-EAP) for advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cisplatin; | 1994 |
A pharmacological pilot study: application of an intermittent schedule of oral uracil and ftorafur (UFT) for hepatocellular carcinoma patients.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Female; Hepatectomy; Humans | 1996 |
UFT plus leucovorin in advanced hepatobiliary tumors and pancreatic adenocarcinomas.
Topics: Adenocarcinoma; Adult; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Cholangiocarcinoma | 1997 |
A crossover study of oral administration of UFT in chronic liver disease: comparison of continuous and intermittent schedules.
Topics: Administration, Oral; Aged; Area Under Curve; Carcinoma, Hepatocellular; Chronic Disease; Cross-Over | 1998 |
UFT plus or minus calcium folinate for metastatic colorectal cancer in older patients.
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy | 1999 |
[Clinical trial of prophylactic hepatic arterial chemotherapy for liver metastases in patients with Dukes' C colorectal cancer].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Adm | 1999 |
Results of pharmacokinetic modulating chemotherapy in combination with hepatic arterial 5-fluorouracil infusion and oral UFT after resection of hepatic colorectal metastases.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe | 2000 |
Improved survival with oral administration of enteric-coated tegafur/uracil for advanced stage IV-A hepatocellular carcinoma.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Drug Combina | 2001 |
A phase II trial of oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepato | 2001 |
Oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carci | 2002 |
Phase II study of uracil-tegafur in patients with metastatic pancreatic cancer.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; | 2002 |
[Randomized trial-comparing UFT and FT in the treatment of advanced hepatocellular carcinoma (second report: well controlled study on patients with transcatheter arterial embolization) Osaka Research Society for Liver, Gallbladder and Pancreas].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoemboliz | 1992 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
[Randomized trial comparing UFT and FT-207 in the treatment of advanced hepatocellular carcinoma (first report: well controlled study on the patients for whom transcatheter arterial embolization could not be applied) Osaka Research Society for Liver, Gall
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Embolization | 1990 |
[Effect of PMU hepatic arterial chemotherapy for liver metastases of gastric cancer. Hokuriku Cisplatin Round-table Conference].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug A | 1989 |
The clinical pharmacology of 5-trifluoromethyl-2'-deoxyuridine.
Topics: Adult; Aged; Antineoplastic Agents; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Clin | 1972 |
242 other studies available for uracil and Liver Neoplasms
| Article | Year |
|---|---|
The effect of prognostic factors at baseline on the efficacy of trifluridine/tipiracil in patients with metastatic colorectal cancer: A Portuguese exploratory analysis.
Topics: Aged; Colonic Neoplasms; Colorectal Neoplasms; Female; Humans; Liver Neoplasms; Male; Portugal; Prog | 2022 |
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; NF-kappa B; Nucleotides; Pyrop | 2022 |
[A Case Report of a Patient Over 90 Years of Age with Liver Metastasis after Sigmoid Colectomy Controlled by a Combination Oral UFT/LV Chemotherapy Regimen].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Female; Humans; Leucov | 2019 |
Application of advanced HepG2 3D cell model for studying genotoxic activity of cyanobacterial toxin cylindrospermopsin.
Topics: Alkaloids; Animals; Arylamine N-Acetyltransferase; Bacterial Toxins; Cyanobacteria Toxins; DNA Damag | 2020 |
Simultaneous quantification method for 5-FU, uracil, and tegafur using UPLC-MS/MS and clinical application in monitoring UFT/LV combination therapy after hepatectomy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Calibration; Chroma | 2021 |
Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Diethylnitro | 2021 |
Genetic variants of DNA repair-related genes predict efficacy of TAS-102 in patients with refractory metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Disease-Free Survival; | 2017 |
Tegafur-uracil-induced rapid development of advanced hepatic fibrosis.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Biopsy; Carcinoma, Hepatocellular; Di | 2017 |
Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone | 2018 |
Successful twice interrupted therapy of HCV infection in patients with cirrhosis with hepatocellular carcinoma before and after liver transplantation.
Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; D | 2017 |
Genotoxic potential of the binary mixture of cyanotoxins microcystin-LR and cylindrospermopsin.
Topics: Alkaloids; Bacterial Toxins; Carcinogens; Carcinoma, Hepatocellular; Cyanobacteria; Cyanobacteria To | 2017 |
[Safety and Efficacy of TAS-102 with Bevacizumab for the Treatment of Unresectable Metastatic Colorectal Cancer - A Case Report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Drug Combinations; Humans; Liver | 2018 |
Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real-world experience study.
Topics: 2-Naphthylamine; Adult; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyc | 2018 |
Concomitant use of sorafenib with ombitasvir/paritaprevir/ritonavir and dasabuvir: Effectiveness and safety in clinical practice.
Topics: 2-Naphthylamine; Aged; Anilides; Antineoplastic Agents; Antiviral Agents; Carbamates; Carcinoma, Hep | 2018 |
Optimizing Treatment Sequence for Late-line Metastatic Colorectal Cancer Patients Using Trifluridine/Tipiracil and Regorafenib.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Administration Schedule; | 2018 |
Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C-Reactive Protein; Colorec | 2018 |
Relationship Between Thymidine Kinase 1 Expression and Trifluridine/Tipiracil Therapy in Refractory Metastatic Colorectal Cancer: A Pooled Analysis of 2 Randomized Clinical Trials.
Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Combinations; Drug Resistance, Neoplasm; Fem | 2018 |
[A Case of Interstitial Pneumonitis Induced by TAS-102 for Liver and Lung Metastasis of Colorectal Cancer].
Topics: Aged; Drug Combinations; Humans; Liver Neoplasms; Lung Diseases, Interstitial; Lung Neoplasms; Male; | 2018 |
A 12-year Recurrence-free Survival After Multidisciplinary Treatment for a Patient With Combined Hepatocellular-Cholangiocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Chol | 2019 |
Recurrence rate of hepatocellular carcinoma in patients with treated hepatocellular carcinoma and hepatitis C virus-associated cirrhosis after ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin therapy.
Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Chemoembol | 2019 |
Genetic polymorphisms of enzymes related to oral tegafur/uracil therapeutic efficacy in patients with hepatocellular carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aryl Hydrocarbon Hydroxylases; Asian People; C | 2013 |
Association between reversal of multidrug resistance by methyl jasmonate and P-glycoprotein ATPase activity in hepatocellular carcinoma.
Topics: Acetates; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Combined Chemothera | 2013 |
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; | 2014 |
Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma.
Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropa | 2016 |
Cost-effectiveness of currently recommended direct-acting antiviral treatments in patients infected with genotypes 1 or 4 hepatitis C virus in the US.
Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbama | 2016 |
Cost-Effectiveness of Genotype 1 Chronic Hepatitis C Virus Treatments in Patients Coinfected with Human Immunodeficiency Virus in the United States.
Topics: 2-Naphthylamine; Adult; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocel | 2016 |
[A Case of Metastatic Colorectal Cancer Refractory to Standard Chemotherapies Treated with TAS-102 with Bevacizumab].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Combined Modality Therapy; Drug Combina | 2016 |
Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.
Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbama | 2017 |
[A case of simultaneous hepatic metastases of ascending colon cancer responding completely to tegafur/uracil plus oral Leucovorin therapy after primary lesion resection].
Topics: Administration, Oral; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Leucovorin; Liver Neopla | 2008 |
[A case of multiple liver metastases of sigmoid colon cancer responding well to UFT+Leucovorin therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leucovorin; Liver Neoplasms; M | 2008 |
[A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptotheci | 2008 |
[Regression of metastatic hepatic cancer from gastric cancer by polysaccharide K and UFT administration--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Humans; Liver Neoplasms; Ma | 2008 |
[A case of metastatic pancreatic cancer after combination chemotherapy with uracil-tegafur and gemcitabine].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Fata | 2009 |
[A case of multiple hepatic metastases of gastric cancer that showed complete regression by systemic chemotherapy using paclitaxel and UFT-E].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor | 2009 |
Complete remission of multiple recurrent hepatocellular carcinomas by oral administration of enteric-coated tegafur/uracil in a patient with huge hepatocellular carcinoma extending to the inferior vena cava after hepatic resection: analysis of mRNA expres
Topics: Administration, Oral; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Combined Modality T | 2009 |
[A case of disease-free survival with low-dose chemotherapy after resection of hepatic and pulmonary metastases from rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Hepatectomy; Humans; Liver Ne | 2009 |
[A case report of multiple liver metastases from colorectal cancer effectively treated with systemic chemotherapy and hepatic arterial infusion].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemothe | 2009 |
[A case report of combined hepatocellular-cholangiocarcinoma whose lymph node recurrence effectively treated with UFT].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neo | 2009 |
[Multiple liver metastases due to sigmoid colon cancer successfully treated by degradable starch microspheres (DSM)-TAE, radiofrequency ablation therapy, and Uzel/UFT].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Catheter Ablation; C | 2010 |
[A case of complete response after treatment with UFT and leucovorin for synchronous multiple liver metastases of rectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leucovorin; Liver Neoplasms; Magneti | 2010 |
[A case of fluoropyrimidine-resistant recurrent colon cancer successfully treated with weekly administration of irinotecan].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Coloni | 2010 |
[A case of hepatocellular carcinoma with autoimmune hepatitis showing marked reduction of tumors by oral administration of UFT-E].
Topics: Administration, Oral; Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biom | 2010 |
[A case of hepatocellular carcinoma with portal vein thrombus(Vp3)and lung metastases(stage IVB),which responded completely to treatment with Tegafur/Uracil].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Humans; Liv | 2010 |
Lethal outcome of 5-fluorouracil infusion in a patient with a total DPD deficiency and a double DPYD and UTG1A1 gene mutation.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Dihydropyrimidine Dehydrog | 2010 |
[A case of advanced rectal cancer with multiple liver metastases successfully treated by perioperative administration of UFT and oral leucovorin].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 2010 |
[A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, | 2010 |
[Hepatic resection after systemic chemotherapy for liver metastasis of colorectal cancer].
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Hu | 2010 |
[A case of synchronous hepatic and multiple pulmonary metastases from rectal cancer responding completely to UFT therapy after resection of primary and hepatic lesions].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Liver Neo | 2011 |
[A case of marked efficacy of low-dose UFT against metastatic bladder cancer].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female | 2011 |
[A case of UFT-induced complete response against multiple lung metastases of hepatocarcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Humans; Liver Neopl | 2011 |
[A case of synchronous multiple liver metastases of rectal cancer successfully treated with tegafur/uracil and oral leucovorin chemotherapy].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combi | 2011 |
[The feasibility of oral fluoropyrimidines as adjuvant chemotherapy after resection and local coagulation therapy of colorectal liver metastases].
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe | 2011 |
[A case of pathological complete response after treatment with uracil/tegafur (UFT) and folinate (Leucovorin) for liver metastasis of colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Female | 2011 |
[A case of laparoscopic radiofrequency ablation for liver metastatic tumor from colorectal carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Colonic Neoplasms; Female; | 2011 |
[Marked response to oral administration of UFT and leucovorin for liver metastases from colon cancer in an elderly patient].
Topics: Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo | 2012 |
[A case of liver metastases of sigmoid colon cancer treated effectively by oral UFT/LV].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leucovor | 2012 |
[A case of successful treatment of granulocyte colony-stimulating factor producing hepatocellular carcinoma accompanying type B hepatitis with tegafur-uracil].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, H | 2012 |
[CPT-11 hepatic arterial injection plus oral UFT administration for liver metastasis of rectal cancer--report of two cases].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptoth | 2002 |
[A case of unresectable rectal cancer with liver and pulmonary metastases that responded remarkably to pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administr | 2002 |
[A patient with hepatocellular carcinoma with intraperitonial lymph node metastases in whom oral UFT treatment was markedly effective].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 2002 |
[A case of multiple liver metastases from colon cancer successfully treated with modified pharmacokinetic modulating chemotherapy using Leucovorin].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Col | 2002 |
[A case of postoperative hepatic metastasis from gastric cancer responding to hepatic arterial infusion chemotherapy of paclitaxel].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Dru | 2002 |
[5-FU pharmacokinetic study of 5-FU hepato-arterial infusion with oral UFT].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2002 |
[Modified pharmacokinetic modulation chemotherapy (PMC) with medication of UFT and intraarterial infusion of 5-FU for advanced unresectable HCC].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Combina | 2002 |
Dihydropyrimidine dehydrogenase (DPD) activity in gastric cancer tissue and effect of DPD inhibitory fluoropyrimidines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehyd | 2003 |
Studies in 2-acetylaminofluorene carcinogenesis. III. The utilization of uracil-2-C14 by preneoplastic rat liver and rat hepatoma.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Fluorenes; Liver Neoplasm | 1954 |
Utilization of uracil by acetylaminofluorene-treated rats.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Fluorenes; Liver Neoplasms; Liver Neoplas | 1955 |
Alternative pathways of thymine and uracil metabolism in the liver and hepatoma.
Topics: Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Thymine; Uracil | 1960 |
Catabolism of xanthine and uracil in tumor-bearing rats.
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Hydantoins; Liver Neoplasms; Neoplasms; N | 1962 |
[ENZYMATIC STUDIES OF CANCER].
Topics: Carcinoma, Hepatocellular; Fluorenes; Liver; Liver Neoplasms; Metabolism; Neoplasms; Neoplasms, Expe | 1964 |
RIBONUCLEIC ACID SYNTHESIS AND TURNOVER IN RAT LIVER AND IN A RAPIDLY GROWING TRANSPLANTABLE HEPATOMA.
Topics: Adenine; Carcinoma, Hepatocellular; Cytosine; Electrophoresis; Guanine; Histocytochemistry; Liver; L | 1964 |
COMPARISON OF THE URACIL CATABOLIC ACTIVITY OF LIVER CELL SUSPENSIONS AND SLICES.
Topics: Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Hepatocytes; Liver; Liver Neoplasms; Met | 1964 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liv | 1965 |
[A case of multiple liver metastases from colon cancer successfully treated with pharmacokinetic modulating chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neop | 2003 |
[Results of prophylactic hepatic arterial chemotherapy for liver metastases of Dukes C colorectal cancer--correlation with tumoral expression of dihydropyrimidine dehydrogenase, thymidylate synthase, p53, or orotate phosphoribosyl transferase].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dihydrouracil Deh | 2003 |
[A case of liver and lung metastases of rectal cancer responding well to 5-FU hepato-arterial infusion (HAI) with combined use of oral UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche | 2003 |
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat | 2003 |
[A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy].
Topics: Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Brain Neoplasm | 2003 |
[A case of advanced gastric cancer with multiple liver metastases responding completely to hepatic arterial infusion and systemic chemotherapies].
Topics: Adenocarcinoma; Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemoth | 2003 |
[A case of liver metastatic recurrence of bile duct cancer completely responding to single drug, UFT, chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bile Duct Neoplasms; Common Bile Duct; Drug Administrat | 2004 |
Competitive action of 2-thiouracil and uracil in AAF-induced cancer of the liver.
Topics: Carcinogenesis; Humans; Liver Neoplasms; Neoplasms; Thiouracil; Uracil | 1951 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
[A case of gastric cancer with a synchronous hepatic metastasis responding to postoperative oral administration of UFT and intermittent intrahepatic arterial chemotherapy of 5-FU].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Adm | 2004 |
[A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Coloni | 2004 |
[Two cases of advanced pancreatic cancer responding to gemcitabine with long survival of 2 years].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cholestasis; Deoxycytidine; Drug Ad | 2004 |
[A case of liver metastases of breast cancer successfully treated by combination chemotherapy using hepatic arterial infusion of docetaxel and systemic administration of trastuzumab].
Topics: Administration, Oral; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplast | 2004 |
[A case of giant hepatocellular carcinoma treatable with radio frequent ablation therapy after effective UFT administration].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 2004 |
Oral administration of uracil-tegafur (UFT) inhibits liver micrometastasis of human colon cancer in an orthotopic nude mouse model and its early detection system.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy | 2004 |
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with gemcitabine hydrochloride, 5-FU, CDDP and administration of tegafur/uracil].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Drug Administration | 2004 |
[Case report--Complete response of liver metastasis of rectal cancer after combination chemotherapy of CPT-11 + UFT-E].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Humans; | 2004 |
[The 5-fluorouracil hepato-arterial infusion with oral UFT therapy for the hepatic and extra hepatic metastases of colorectal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dr | 2004 |
[A case report--Efficacy of combination therapy to unresectable advanced gall bladder carcinoma--palliative operation, hepatic arterial infusion therapy, and radiation therapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Combined | 2004 |
[A case of long-term survivor with multiple pulmonary metastases of HCC after hepatic resection].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Combinati | 2004 |
[A case of liver metastases from cecal cancer successfully treated with fluorouracil and folinic acid (UFT/LV)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Chemotherapy, | 2005 |
[Pharmacokinetic modulating chemotherapy for rectal carcinoma metastases to the liver and lung--a case report].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru | 2005 |
[A case with advanced carcinoma of the gallbladder responding to UFT monotherapy].
Topics: Adenocarcinoma, Papillary; Administration, Oral; Aged; Antineoplastic Agents; Drug Combinations; Fem | 2005 |
[A case of anthracycline and taxane-resistant breast cancer with life-thereatening multiple liver metastases responding to oral combination chemotherapy by UFT, cyclophosphamide and medroxyprogesterone acetate].
Topics: Adenocarcinoma, Scirrhous; Administration, Oral; Anthracyclines; Antineoplastic Combined Chemotherap | 2005 |
[Combined chemotherapy with oral leucovorin (LV) + tegafur/uracil (UFT) and hepatic arterial infusion (HAI) therapy for liver metastasis of colorectal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dr | 2005 |
The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo | 2006 |
Long-term survival after hepatectomy for hepatic recurrence of carcinoma of the papilla of Vater.
Topics: Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Aged; Ampulla of Vater; Antineoplastic Combined | 2005 |
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combi | 2005 |
[A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colect | 2005 |
[A case of multiple hepatic and peritoneal metastases from colon cancer responding to oral UFT+leucovorin chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Col | 2005 |
[Hepatic arterial infusion (HAI) chemotherapy achieved a complete response (CR) for multiple liver metastases of colorectal cancer--two case reports].
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic C | 2005 |
[A successful surgical treatment for solitary pulmonary and adrenal metastases after hepatic resection to hepatocellular carcinoma--a case report].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2005 |
[A 6-year-survival case of esophageal adenosquamous cancer with liver metastases cured by multidisciplinary therapy].
Topics: Aged; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenosquamou | 2006 |
[A case of hepatic metastases of sigmoid colon cancer which completely responded to systemic l-leucovorin/5-FU therapy and oral LV/UFT combination therapy].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche | 2006 |
[Second-line chemotherapy with pharmacokinetic modulating chemotherapy for unresectable colorectal carcinoma recurrences resistant to 5-FU-based chemotherapy].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Co | 2006 |
[Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report].
Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc | 2006 |
[A case of recurrent pancreatic cancer responding to TS-1 combined gemcitabine chemotherapy after UFT combined gemcitabine chemotherapy resulting progressive disease].
Topics: Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Administration Schedule; Drug Co | 2006 |
[A case of recurrent gastric cancer with dihydropyrimidine dehydrogenase (DPD) deficiency].
Topics: Adult; Anorexia; Antimetabolites, Antineoplastic; Bone Neoplasms; Cerebral Hemorrhage; Dihydropyrimi | 2006 |
[A patient with pancreatic cancer and multiple liver metastases after total pancreatectomy who showed a partial response to combination chemotherapy with gemcitabine and UFT].
Topics: Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Combined Mod | 2006 |
[A case of effective multidisciplinary treatment with hepatic resection for synchronous multiple liver metastases from rectal cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubic | 2006 |
[Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma providing a good QOL].
Topics: Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; | 2006 |
[A long survival case of sigmoid colon cancer patient with initially unresectable hepatic metastases].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fluoroura | 2007 |
[A case of liver metastasis of gastric cancer undergoing non-curative operation responding completely to combination therapy of S-1 and CDDP].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Adm | 2007 |
[A case of unresectable colon cancer responding to oral leucovorin+oral tegafur/uracil].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colon, Sigmoid | 2007 |
Successful treatment with low-dose oral chemotherapy in a patient with metastatic hepatocellular carcinoma.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 2007 |
[A case report--combination chemotherapy with oral UFT and CPT-11, 5-FU, l-LV by hepatic arterial infusion for multiple hepatic metastasis from sigmoid colon cancer].
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineopla | 2007 |
[A case of complete remission(CR)persisting from UFT-E in an old patient with liver metastasis of gastric cancer].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Liver Neoplasms; | 2008 |
[Effective treatment with oral administration of UFT and leucovorin (Uzel) in a patient with liver metastasis and peritoneal dissemination from cecal cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Female; | 2008 |
[Clinical experiences with UFD-1].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combination | 1982 |
Inhibitory effect of simultaneous intraportal administration of 5-fluorouracil, uracil and degradable starch microspheres on experimental hepatic micrometastasis, is of colon cancer.
Topics: Animals; Colorectal Neoplasms; Fluorouracil; Infusions, Intravenous; Liver Neoplasms; Male; Mice; Mi | 1994 |
Postoperative prophylactic lipiodolization reduces the intrahepatic recurrence of hepatocellular carcinoma.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Che | 1995 |
[A case of gastric cancer with multiple liver metastasis responding to combined therapy with UFT and mitomycin C].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined | 1995 |
[A case of hepatocellular carcinoma with bone metastasis responding to oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Hep | 1995 |
[A case of multiple liver metastasis from remnant gastric cancer responding to leucovorin.5-FU+UFT therapy].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Adm | 1995 |
[A case of huge liver metastasis from jejunal leiomyosarcoma completely controlled by intra-arterial and intra-portal vein infusion chemotherapy following hepatectomy].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sch | 1994 |
[A case of small cell carcinoma of the stomach with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; | 1994 |
[A case of hepatocellular carcinoma whose lung metastases and tumor emboli in the inferior vena cava disappeared by oral administration of UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 1994 |
[Portal-transfer of an orally administered anti-cancer agent analysis of the time course of portal blood and systemic blood levels of preoperatively administered UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dr | 1994 |
[A comparative study on the serum and tissue 5-FU concentrations in patients with hepatocellular carcinoma after preoperative oral administration of UFT and 5'-DFUR].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepato | 1994 |
[A case of advanced hepatocellular carcinoma, in which the tumor almost disappeared by orally administered UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; | 1993 |
[Vanishing tumor thrombus in IVC after oral administration of UFT and TAE in a patient with HCC; a case report].
Topics: Aged; Carcinoma, Hepatocellular; Combined Modality Therapy; Drug Combinations; Embolization, Therape | 1993 |
[A case of giant hepatocellular carcinoma effectively treated by UFT].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biomarkers, Tum | 1993 |
[A case of hepatocellular carcinoma with portal invasion and right adrenal gland metastasis showing marked contraction of primary tumor and metastasis with treated by UFT alone].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocell | 1994 |
Effect of 5-fluorouracil and UFT on experimental liver metastasis model of colorectal cancer using mouse colon 26 cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Combinations; Drug | 1993 |
[The present status of chemotherapy for hepatocellular carcinoma].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcino | 1993 |
[A case of gastric cancer with multiple liver metastases showing marked efficacy of preoperative and postoperative chemotherapy with CDDP, MMC and UFT(PMU), or CDDP, MMC, UFT and etoposide (PMUE)].
Topics: Adenocarcinoma, Papillary; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv | 1993 |
[A case of advance colon cancer responding to sequential methotrexate and 5-fluorouracil therapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administrati | 1993 |
[A case of advanced gastric cancer responding to chemotherapy and radiotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cispl | 1996 |
[A case of hepatocellular carcinoma with reduction of primary tumor and disappearance of multiple lung metastasis].
Topics: Administration, Oral; Carcinoma, Hepatocellular; Drug Combinations; Humans; Liver Neoplasms; Lung Ne | 1996 |
[A case of hepatocellular carcinoma responding to oral administration of UFT].
Topics: Administration, Oral; Aged; alpha-Fetoproteins; Biomarkers; Carcinoma, Hepatocellular; Drug Combinat | 1996 |
[A case of early gastric cancer transformed from adenoma by chemotherapy and radiotherapy].
Topics: Adenoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Cyclophosp | 1996 |
[Successful UFT-E granule and 5-FUCDDP combination therapy for an unresectable advanced gastric cancer complicated with liver metastasis].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality T | 1996 |
[A case of advanced gastric cancer with multiple liver metastasis successfully treated with combination chemotherapy using UFT, CDDP and etoposide].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration | 1996 |
A case of advanced gastric cancer complicated by severe toxicity induced by a combination of tegafur, uracil and mitomycin C, and associated with abnormal pharmacokinetics.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Marrow Diseas | 1996 |
[A case of advanced gastric cancer showing complete disappearance of cancer cells in multiple liver metastases due to low-dose PMUE therapy].
Topics: Adenocarcinoma, Papillary; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Adm | 1996 |
[Antimetastatic effects of UFT on murine liver metastasis model using L5178YHM lymphoma].
Topics: Animals; Body Weight; Drug Combinations; Floxuridine; Leukemia L5178; Liver Neoplasms; Male; Mice; T | 1996 |
[A case of hepatocellular carcinoma with reduction of primary tumor and disappearance of multiple lung metastasis].
Topics: Administration, Oral; alpha-Fetoproteins; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepat | 1998 |
[Complete disappearance of metastatic pulmonary tumors in a case of hepatocellular carcinoma treated with UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 1998 |
[A case of giant hepatocellular carcinoma effectively treated with UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 1998 |
[Complete remission of liver metastasis from rectal cancer following continuous oral administration of tegafur-uracil after intrahepatic arterial single injection of CDDP and 5-FU].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinat | 1998 |
Effects of systemic and regional chemotherapy after hepatic resection for colorectal metastases.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 1998 |
Complete remission of multiple hepatocellular carcinomas associated with hepatitis C virus-related, decompensated liver cirrhosis by oral administration of enteric-coated tegafur/uracil.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr | 1999 |
[Effective chemo-endocrine combination therapy for obstructive-jaundice caused by multiple liver metastasis of recurrent breast cancer--a case report].
Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neopla | 1999 |
[A case of advanced gastric cancer (type 3) with pyloric stenosis, multiple liver and lymph node metastases responding to UFT-E granules and lentinan].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Humans; Len | 2000 |
[A case of advanced gastric cancer with hepatic metastasis successfully treated by combined chemotherapy with UFT and lentinan].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; | 2000 |
[A case of advanced hepatocellular carcinoma with lung and bone metastases effectively treated by orally administered UFT].
Topics: Administration, Oral; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers | 2000 |
Complete disappearance of recurrent hepatocellular carcinoma with peritoneal dissemination and splenic metastasis: a unique clinical course after surgery.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Drug Thera | 2000 |
[A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modal | 2000 |
[A case report of unresectable colon cancer that disappeared following pharmacokinetic modulation chemotherapy (PMC)].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug | 2000 |
[A successful case of preoperative intermittent hepatic arterial infusion of high-dose 5-FU and pharmacokinetic modulating chemotherapy against unresectable liver metastasis of colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Sched | 2000 |
[A case of breast cancer with multiple metastases successfully treated by medroxyprogesterone acetate with intermittent intra-arterial infusion low-dose chemotherapy to hepatic metastasis].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bre | 2000 |
[Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptotheci | 2000 |
[Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Fluorouracil; He | 2000 |
Advanced hepatocellular carcinoma with distant metastases, successfully treated by a combination therapy of alpha-interferon and oral tegafur/uracil.
Topics: Administration, Oral; Adult; Angiography; Antimetabolites, Antineoplastic; Antineoplastic Agents; An | 2000 |
[Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru | 2001 |
[A case of gastric cancer with liver metastases successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].
Topics: Administration, Oral; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineopla | 2001 |
[Complete response of a massive hepatocellular carcinoma with lung metastasis to UFT (DPD inhibitory fluoroprymidines: DIF)].
Topics: Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Combinations; Humans; Liver Neoplasms; | 2001 |
[A case of advanced gastric cancer complicated with liver metastases responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin, with UFT and low-dose cisplatin for maintenance on an outpatient basis].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil | 2001 |
[A case of successful management of nonresectable pancreas cancer with liver metastasis by intra-arterial infusion chemotherapy with angiotensin-II and administration of tegafur/uracil].
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans | 2001 |
[Relationship between the anti-metastatic effect of UFT and in vitro chemosensitivity to 5-FU in metastatic tumors from orthotopic implanted colon cancer in nude rats].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Combinations; Drug Screening Assays, Antitum | 2001 |
Extraction of 5-fluorouracil by tumor and liver: a noninvasive positron emission tomography study of patients with gastrointestinal cancer.
Topics: Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Enzyme Inhibitors; Fluorine Rad | 2001 |
[A case of advanced gastric cancer with multiple liver metastases in an elderly patient that responded dramatically to UFT therapy].
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Combined Modal | 2001 |
[A case of breast cancer with multiple metastases effectively treated with long-term administration of docetaxel, aclarubicin and UFT].
Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast | 2001 |
[A case of spindle cell type hepatocellular carcinoma responding to hepatic intra-arterial infusion chemotherapy].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Dru | 2002 |
[A case of complete response (CR) persisting for 2 years and 10 months from UFT-E in a patient with liver metastasis of gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Drug Administr | 2002 |
[A case of liver metastasis of rectal cancer demonstrating complete response to 5-FU + Leucovorin + UFT].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug C | 2002 |
[A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Hepatic Artery; | 2002 |
Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.
Topics: Adenine; Animals; Biological Transport, Active; Calorimetry; Carcinoma, Hepatocellular; Cell Line; C | 1975 |
Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; DNA; DNA, Bact | 1975 |
The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Hydroxyu | 1977 |
Radioactive nucleic acids-precursors: their potential value as tumor-localizing agents.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Iodine Radioisotopes; Leukemia, Lymphoid; Liv | 1977 |
Incorporation characteristics of uracil, uridine, and orotic acid into ribonucleic acid of neoplastic cells.
Topics: Adult; Aged; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Female; Humans; Liver; Li | 1977 |
Uridine transport in Novikoff rat hepatoma cells and other cell lines and its relationship to uridine phosphorylation and phosphorolysis.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line; Chloromercuribenzoates; Liver | 1978 |
[Sharp decline in plasma CEA and reduction of liver metastasis after UFT administration in a patient with recurrent gastric cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoembr | 1992 |
[PMUE therapy (CDDP, MMC, UFT, etoposide) for advanced gastric cancer--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Etoposide; | 1992 |
[A case of gastric cancer with multiple liver metastases effectively treated with PMUE (CDDP, MMC, UFT, etoposide) hepatic arterial chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Administrati | 1992 |
[Effects of UFT and loxiglumide (CR1505) on liver metastasis of human pancreatic cancer cell line, KP-1 N in nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholecystokinin; Humans; Liv | 1992 |
[A case of advanced gastric cancer with liver metastasis completely responding to a combined immunochemotherapy with UFT, mitomycin C and lentinan].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Lentinan; Liver Neopla | 1992 |
[A resected case of advanced gastric cancer with complete remission of liver metastasis by chronic daily administration of oral etoposide and UFT].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche | 1992 |
[Rupture of hepatocellular carcinoma with multiple pulmonary metastasis successfully treated by transcatheter arterial embolization (TAE) of tumor: a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, | 1991 |
[Antitumor activity of T-506, a novel synthetic FUDR derivative, on murine colon cancer and its hepatic metastasis].
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; F | 1991 |
[Regional immunochemotherapy for liver metastasis of esophageal cancer in a patient with variant hepatic artery].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisp | 1991 |
[Effect of UFT by oral administration using a murine hepatic metastasis model].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Hu | 1991 |
[Clinical experiences with hyperthermochemotherapy of hepatic metastasis from gastric cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Moda | 1991 |
[CDDP-ip PMUE therapy in gastric cancer cases with liver metastasis].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; | 1991 |
Primary adenocarcinoma of duodenal bulb benefitted by chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Duodenal Neoplasms; Humans; Liver Ne | 1991 |
[Tissue UFT distribution and histological changes following UFT administration in metastatic liver cancer cases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Human | 1990 |
[Results of prophylactic intra-arterial infusion chemotherapy after hepatic resection in colorectal metastases].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorour | 1990 |
The effect of UFTM therapy on primary and metastatic colon cancer from the same human xenotransplanted into nude mice.
Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colo | 1990 |
[Therapy of hepatocellular carcinoma with UFT--clinical evaluation of its effect in the combination therapy with transcatheter arterial embolization or one shot therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality T | 1990 |
[A case of biliary tract obstruction due to metastatic hepatic cancer, in which topical injection of CDDP and ADM into PTCD with concomitant use of UFT resulting in partial reopening of biliary tract].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Ducts, Intrahepatic; Catheters, Indwelling; Cho | 1989 |
[Study on the pharmacokinetics of UFT in patients with hepatocellular carcinoma associated with cirrhosis].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Female; Fluo | 1989 |
[Almost complete disappearance of metastatic pulmonary tumor and reduction of the main hepatic mass in a case of hepatocellular carcinoma treated with UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Fem | 1987 |
[A case of hepatocellular carcinoma with extrahepatic portal vein obstruction due to tumor invasion, responsive to oral administration of UFT].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellul | 1987 |
[5-Fluorouracil, tegafur, and uracil concentrations in serum and tissue of the patients with hepatocellular carcinoma after UFT administration].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Combinations; Fluoro | 1987 |
[Effects and side effects of long-term administration of oral antitumor agents in patients with hepatocellular carcinoma--especially, relation to aggravation of liver function].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality T | 1987 |
[Anticancer effect of UFT in intrahepatic recurrence with tumor embolus in the left portal vein after hepatectomy of hepatoma--a case report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Hepatectomy; Humans | 1988 |
[Risk factors for side effects of long-term administration of 5-fluorouracil derivatives in patients with hepatocellular carcinoma associated with liver cirrhosis--relationship with serum concentration of anti-tumor agents and side effect].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Brain Diseases; Carcinoma, Hepatocell | 1988 |
Uridine phosphorylase from Novikoff rat hepatoma cells: purification, kinetic properties, and its role in uracil anabolism.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cricetinae; Humans; Inosine; Kinetics; | 1985 |
Phase II study of co-administration of uracil and tegafur (UFT) in hepatocellular carcinoma. Tokyo Liver Cancer Chemotherapy Study Group.
Topics: Administration, Oral; Aged; Carcinoma, Hepatocellular; Drug Combinations; Female; Humans; Liver Neop | 1985 |
[Maintenance chemotherapy by UFT after trans-arterial embolization for hepatocellular carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy | 1986 |
[An unresectable case of hepatoma completely disappearing after oral administration of an anticancer drug (UFT)].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellula | 1986 |
[A case of hepatocellular carcinoma with bone metastasis which responded to oral administration of UFT].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Hepatocellular; Humans; L | 1987 |
[Clinical evaluation of MMC-mc-chemoembolization therapy and its combination with UFT in hepatocellular carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Adminis | 1987 |
[FT, 5-FU and uracil concentrations of the blood, bile and tissue of hepatoma with liver cirrhosis after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Bile; Carcinoma, Hepatocellula | 1987 |
[Effects of preoperative administration of UFT in gastrointestinal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Humans; Kine | 1986 |
[Effects of oral administration of UFT in unresectable gastric cancer with liver metastasis].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Liver Neoplasms; Male; Middl | 1986 |
[A case of relapsed gastric cancer treated successfully by chemotherapy--lung metastasis and relapsed cancer in the hepatic portal system].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Humans; Liver | 1986 |
[Changes in CT findings in patients with liver metastases of breast cancer during effective intra-arterial infusion].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Humans; Infusion Pump | 1988 |
[Effects of UFT on experimental liver metastases and on the immunologic capacity of the hosts].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Immune Tolera | 1988 |
Improved high-performance liquid chromatographic assay for the quantification of 5-bromo-2'-deoxyuridine and 5-bromouracil in plasma.
Topics: Aged; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Colonic Neoplasms; Human | 1988 |
[Intra-arterial infusion chemotherapy using a subcutaneously implanted silicone reservoir--with reference to the chemotherapy protocol].
Topics: Abdominal Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cytarabi | 1985 |
[A combined chemotherapy with UFT and mitomycin C in advanced gastric cancer; report of 2 cases].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administr | 1985 |
Effect of ultraviolet light on mengovirus: formation of uracil dimers, instability and degradation of capsid, and covalent linkage of protein to viral RNA.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradien | 1974 |
Post-transcriptional inhibition of protein synthesis by rifampicin in rat hepatoma cells.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; DNA- | 1973 |
Differential sensitivity of rat liver and rat hepatoma cells to alpha-amanitin.
Topics: Adrenalectomy; Animals; Basidiomycota; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus | 1973 |
Activities of DNA nucleotidyltransferases and other enzymes in cell-free preparations from hepatomas of different growth rates.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyt | 1966 |
[Feedback-regulation of aspartate-transcarbamylase of various tissues].
Topics: Adenosine Triphosphate; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Cytosine Nucleoti | 1966 |
[Determination of 4-methyluracil in the serum of normal and tumorous rats].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Chromatography, Paper; Injections, Intrap | 1967 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; | 1971 |
Enzyme patterns in a group of transplantable mouse hepatomas of different growth rates.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Growth; Humans; Inbreeding; Liver; Liver Neoplas | 1971 |
[Experimental findings concerning the antineoplastic drug fluordopan].
Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Liver Neoplasms; Lymphoma | 1971 |
MOdified nucleosides of nuclear and nucleolar low molecular weight ribonucleic acid.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Chromatography, Gel; Chro | 1972 |
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluoroura | 1973 |
1-Nitroso-5, 6-dihydrouracil: induction of liver cell carcinomas and kidney adenomas in the rat.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Female; Kidney Neoplasms; Lethal Dose 50; Liver Neoplas | 1973 |
Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Fluorouracil; Inje | 1974 |
Dihydrouracil dehydrogenase activity in normal, differentiating and regnerating liver and in hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Cell Division; Female; Liver; Liver Neoplasms; Liver | 1971 |
[Long-term intra-arterial infusion in the chemotherapy of cancer of the liver (preliminary communication)].
Topics: Adult; Catheterization; Celiac Artery; Female; Humans; Injections, Intra-Arterial; Liver Neoplasms; | 1973 |
A new method for treatment of carcinoma of the breast and colon with 5-fluorouracil.
Topics: Adult; Aged; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Female; Fluorouraci | 1970 |