Page last updated: 2024-10-20

uracil and Koch's Disease

uracil has been researched along with Koch's Disease in 10 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
"The upp (Rv3309c)-encoded uracil phosphoribosyltransferase from Mycobacterium tuberculosis (MtUPRT) converts uracil and 5-phosphoribosyl-α-1-pyrophosphate into pyrophosphate and uridine 5΄-monophosphate, the precursor of all pyrimidine nucleotides."7.85Analysis of uracil phosphoribosyltransferase expression in Mycobacterium tuberculosis and evaluation of upp knockout strain in infected mice. ( Basso, LA; Campos, MM; Grzegorzewicz, AE; Jackson, M; Jones, V; Pham, H; Rodrigues-Junior, VD; Santos, DS; Villela, AD, 2017)
"The upp (Rv3309c)-encoded uracil phosphoribosyltransferase from Mycobacterium tuberculosis (MtUPRT) converts uracil and 5-phosphoribosyl-α-1-pyrophosphate into pyrophosphate and uridine 5΄-monophosphate, the precursor of all pyrimidine nucleotides."3.85Analysis of uracil phosphoribosyltransferase expression in Mycobacterium tuberculosis and evaluation of upp knockout strain in infected mice. ( Basso, LA; Campos, MM; Grzegorzewicz, AE; Jackson, M; Jones, V; Pham, H; Rodrigues-Junior, VD; Santos, DS; Villela, AD, 2017)
"Here we treated M."1.62Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates. ( Arlehamn, CSL; Barber, DL; Barry Iii, CE; Dorosky, DE; Fleegle, JD; Freeman, GJ; Gomez, F; Kauffman, KD; Lora, NE; Namasivayam, S; Oh, S; Sakai, S; Sette, A; Sher, A; Via, LE, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Sakai, S1
Lora, NE1
Kauffman, KD1
Dorosky, DE1
Oh, S1
Namasivayam, S1
Gomez, F1
Fleegle, JD1
Arlehamn, CSL1
Sette, A1
Sher, A1
Freeman, GJ1
Via, LE1
Barry Iii, CE1
Barber, DL1
Wang, Y2
Liu, D1
Deng, J1
Xu, J1
Ye, C1
Matyugina, E1
Novikov, M1
Babkov, D1
Ozerov, A1
Chernousova, L1
Andreevskaya, S1
Smirnova, T1
Karpenko, I1
Chizhov, A1
Murthu, P1
Lutz, S1
Kochetkov, S1
Seley-Radtke, KL1
Khandazhinskaya, AL1
Villela, AD1
Pham, H1
Jones, V1
Grzegorzewicz, AE1
Rodrigues-Junior, VD1
Campos, MM1
Basso, LA1
Jackson, M1
Santos, DS1
Srivastav, NC1
Rai, D1
Tse, C1
Agrawal, B1
Kunimoto, DY1
Kumar, R1
Stach, JL1
Gros, P1
Forget, A1
Skamene, E1
Zabaleta, J1
Arias, M1
Maya, JR1
García, LF1
Nau, GJ1
Liaw, L1
Chupp, GL1
Berman, JS1
Hogan, BL1
Young, RA1
Zabolotnykh, NV1
Aleksandrova, AE1
Rook, GA1
Champion, BR1
Steele, J1
Varey, AM1
Stanford, JL1

Other Studies

10 other studies available for uracil and Koch's Disease

ArticleYear
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates.
    Mucosal immunology, 2021, Volume: 14, Issue:5

    Topics: Animals; Biomarkers; Cytokines; Disease Management; Disease Susceptibility; Host-Pathogen Interactio

2021
Loop-mediated isothermal amplification using self-avoiding molecular recognition systems and antarctic thermal sensitive uracil-DNA-glycosylase for detection of nucleic acid with prevention of carryover contamination.
    Analytica chimica acta, 2017, Dec-15, Volume: 996

    Topics: Biosensing Techniques; DNA; DNA Primers; Humans; Mycobacterium tuberculosis; Nucleic Acid Amplificat

2017
5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis.
    Chemical biology & drug design, 2015, Volume: 86, Issue:6

    Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Chlorocebus aethiops; Drug Design; Enzyme Inhibito

2015
Analysis of uracil phosphoribosyltransferase expression in Mycobacterium tuberculosis and evaluation of upp knockout strain in infected mice.
    FEMS microbiology letters, 2017, 02-01, Volume: 364, Issue:4

    Topics: Animals; Bacterial Proteins; Disease Models, Animal; Gene Expression; Gene Knockout Techniques; Mice

2017
Inhibition of mycobacterial replication by pyrimidines possessing various C-5 functionalities and related 2'-deoxynucleoside analogues using in vitro and in vivo models.
    Journal of medicinal chemistry, 2010, Aug-26, Volume: 53, Issue:16

    Topics: Alkynes; Animals; Antitubercular Agents; Cell Line, Tumor; Deoxycytidine; Deoxyribonucleosides; Huma

2010
Phenotypic expression of genetically-controlled natural resistance to Mycobacterium bovis (BCG).
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 132, Issue:2

    Topics: Animals; Chromosome Mapping; Dose-Response Relationship, Immunologic; Female; Immunity, Innate; Kine

1984
Diminished adherence and/or ingestion of virulent Mycobacterium tuberculosis by monocyte-derived macrophages from patients with tuberculosis.
    Clinical and diagnostic laboratory immunology, 1998, Volume: 5, Issue:5

    Topics: Bacterial Adhesion; Cells, Cultured; Colony Count, Microbial; Culture Media, Serum-Free; Flow Cytome

1998
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin.
    Infection and immunity, 1999, Volume: 67, Issue:8

    Topics: Animals; Cytokines; Granuloma; Hyaluronan Receptors; Interferon-gamma; Macrophages; Mice; Mycobacter

1999
[Efficacy of immunotropic drugs in experimental tuberculosis].
    Problemy tuberkuleza, 1985, Issue:11

    Topics: Animals; Drug Therapy, Combination; Guinea Pigs; Isoniazid; Levamisole; Mice; Thymus Hormones; Tuber

1985
I-A restricted activation by T cell lines of anti-tuberculosis activity in murine macrophages.
    Clinical and experimental immunology, 1985, Volume: 59, Issue:2

    Topics: Animals; Cells, Cultured; Female; Histocompatibility Antigens Class II; Macrophage Activation; Major

1985