uracil has been researched along with Invasiveness, Neoplasm in 30 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Excerpt | Relevance | Reference |
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"This phase II study evaluated the efficacy and safety of anastrozole concurrent with tegafur/uracil (UFT) as neoadjuvant therapy for ER-positive postmenopausal breast cancer." | 9.27 | Randomized phase II study of anastrozole plus tegafur-uracil as neoadjuvant therapy for ER-positive breast cancer in postmenopausal Japanese women (Neo-ACET BC). ( Aono, T; Ito, T; Kagimura, T; Masuda, N; Matsunami, N; Miyoshi, Y; Nakayama, T; Noguchi, S; Sagara, Y; Taguchi, T; Takashima, T, 2018) |
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination." | 5.51 | 1-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019) |
"This phase II study evaluated the efficacy and safety of anastrozole concurrent with tegafur/uracil (UFT) as neoadjuvant therapy for ER-positive postmenopausal breast cancer." | 5.27 | Randomized phase II study of anastrozole plus tegafur-uracil as neoadjuvant therapy for ER-positive breast cancer in postmenopausal Japanese women (Neo-ACET BC). ( Aono, T; Ito, T; Kagimura, T; Masuda, N; Matsunami, N; Miyoshi, Y; Nakayama, T; Noguchi, S; Sagara, Y; Taguchi, T; Takashima, T, 2018) |
"The objectives of this study were to evaluate the efficacy and toxicity of a fixed dose-rate infusion of gemcitabine associated with uracil/tegafur (UFT) in patients with advanced adenocarcinoma of the pancreas." | 5.10 | Phase II study of a fixed dose-rate infusion of gemcitabine associated with uracil/tegafur in advanced carcinoma of the pancreas. ( Bolaños, M; Borrega, P; Castro, J; Dorta, J; Escudero, P; Espinosa, E; Feliu, J; González Barón, M; López Gómez, L; Mel, R; Vázquez-Estévez, SE, 2002) |
"Metronomic chemotherapy using the 5-FU prodrug uracil-tegafur (UFT) and cyclophosphamide (CTX) was previously shown to only modestly delay primary tumor growth, but nevertheless markedly suppressed the development of micro-metastasis in an orthotopic breast cancer xenograft model, using the metastatic variant of the MDA-MB-231 cell line, 231/LM2-4." | 3.91 | Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion. ( Cruz-Muñoz, W; Hileeto, D; Kerbel, RS; Man, S; Muñoz, R; Viloria-Petit, A; Wood, GA; Xu, P, 2019) |
"The high mortality of epithelial ovarian cancer (EOC) is primarily due to vast intraperitoneal dissemination." | 1.51 | 1-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer. ( Gao, H; Guo, X; Li, X; Liu, N; Peng, J; Yang, X, 2019) |
"These findings were observed in breast cancer cell lines with an invasive phenotype and were further confirmed in ZFP36-knockout mouse fibroblasts." | 1.39 | miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer. ( Al-Ahmadi, W; Al-Ghamdi, M; Al-Souhibani, N; Khabar, KS, 2013) |
"Herein, we report a bladder cancer case with multiple metastases which were controlled by low-dose UFT." | 1.37 | [A case of marked efficacy of low-dose UFT against metastatic bladder cancer]. ( Arai, Y; Ito, A; Kuwahara, M; Nakano, O; Satoh, M, 2011) |
" The regimen of pre-op CCRT was a radiation dosage of 45 Gy in 20 fractions and oral tegafur-uracil (UFUR) and leucovorin." | 1.36 | The impact of preoperative chemoradiotherapy on advanced low rectal cancer. ( Chang, SC; Chen, WS; Jiang, JK; Kao, PS; Lee, RC; Liang, WY; Lin, JK; Lin, TC; Wang, HS; Wang, LW; Yang, SH, 2010) |
"We present a case of esophageal cancer with multiple lymph node metastases successfully performed early response evaluation for preoperative chemotherapy by FDG-PET." | 1.35 | [Case of esophageal cancer successfully performed in early response evaluation for preoperative chemotherapy by FDG-PET]. ( Arakaki, K; Isa, T; Kaneshiro, T; Nakachi, A; Nishimaki, T; Shiroma, H; Teruya, T; Yamamoto, H, 2008) |
"A resected case of squamous cell carcinoma associated with ductal carcinoma in the hemilateral breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases is reported with some discussion." | 1.34 | [A resected case of squamous cell carcinoma of the breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases]. ( Akagawa, T; Fujioka, S; Hara, T; Hiramatsu, K; Hirata, A; Ito, T; Kato, K; Kutsuna, Y; Machiki, Y; Matsuba, H; Miyata, T, 2007) |
"The data on 307 patients with colorectal cancer at stage II or III, who underwent potentially curative resection with lymphadenectomy, were reviewed." | 1.33 | The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. ( Ikeda, S; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Ogo, S; Ohkita, A; Ozasa, H; Sasatomi, T; Shirouzu, K, 2006) |
"In stage 3 gastric cancer, the overall survival rates following surgery was significantly (p < 0." | 1.31 | Postsurgical sequential methotrexate, fluorouracil, and leucovorin for stages 3 and 4 gastric carcinoma: A preliminary study. ( Kitaoka, A; Ohsumi, K; Tokuka, A; Tokunaga, Y; Yagi, T, 2000) |
"Macroscopically it was gastric cancer with P0H3N1T3M0, Stage IV b, histologically small cell carcinoma, intermed, INF gamma, ss, ly1, v3, n1(+), ow(-), aw(-)." | 1.29 | [A case of small cell carcinoma of the stomach with multiple liver metastases]. ( Ishizawa, S; Masuyama, K; Oonishi, Y; Sawataishi, M; Suzuki, S; Wakaki, K; Yamazaki, K, 1994) |
"A 79-year-old female with hepatocellular carcinoma with portal invasion and right adrenal gland metastasis was treated by low dose UFT (200 mg/day)." | 1.29 | [A case of hepatocellular carcinoma with portal invasion and right adrenal gland metastasis showing marked contraction of primary tumor and metastasis with treated by UFT alone]. ( Itoh, Y; Ohkawa, S; Tamai, S; Tarao, K, 1994) |
"A diagnosis of hepatocellular carcinoma with extrahepatic portal venous obstruction due to tumor invasion was made." | 1.27 | [A case of hepatocellular carcinoma with extrahepatic portal vein obstruction due to tumor invasion, responsive to oral administration of UFT]. ( Kuroda, K; Maeda, S; Nagase, T; Nakagawa, C; Nakanishi, T; Nishikawa, M; Tokunaga, K, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (3.33) | 18.7374 |
1990's | 5 (16.67) | 18.2507 |
2000's | 12 (40.00) | 29.6817 |
2010's | 11 (36.67) | 24.3611 |
2020's | 1 (3.33) | 2.80 |
Authors | Studies |
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Muñoz, R | 1 |
Hileeto, D | 1 |
Cruz-Muñoz, W | 1 |
Wood, GA | 1 |
Xu, P | 1 |
Man, S | 1 |
Viloria-Petit, A | 1 |
Kerbel, RS | 1 |
Tsuchiya, T | 2 |
Kamohara, R | 2 |
Muraoka, M | 2 |
Nagayasu, T | 1 |
Saeki, S | 1 |
Takenoyama, M | 1 |
Suzuki, M | 1 |
Inada, K | 2 |
Tokunaga, S | 1 |
Hayashi, T | 1 |
Urabe, S | 2 |
Koga, T | 1 |
Akamine, S | 2 |
Sugio, K | 1 |
Nakayama, T | 1 |
Sagara, Y | 1 |
Takashima, T | 1 |
Matsunami, N | 1 |
Masuda, N | 1 |
Miyoshi, Y | 1 |
Taguchi, T | 1 |
Aono, T | 1 |
Ito, T | 2 |
Kagimura, T | 1 |
Noguchi, S | 1 |
Peng, J | 2 |
Yang, X | 1 |
Li, X | 1 |
Gao, H | 1 |
Liu, N | 1 |
Guo, X | 1 |
Maeda, T | 1 |
Hashimoto, K | 1 |
Ishida, T | 1 |
Yamashita, Y | 2 |
Saeki, H | 1 |
Kawanaka, H | 1 |
Uchiyama, H | 1 |
Ikeda, T | 1 |
Tsujitani, S | 1 |
Maehara, Y | 1 |
Tashiro, J | 1 |
Yamaguchi, S | 1 |
Ishii, T | 1 |
Suzuki, A | 1 |
Kondo, H | 1 |
Morita, Y | 1 |
Hara, K | 1 |
Koyama, I | 1 |
Chen, X | 1 |
Hu, Q | 1 |
Yang, M | 1 |
Liu, H | 1 |
Wei, W | 1 |
Liu, S | 1 |
Wang, H | 1 |
Kim, SG | 1 |
Hwang, SH | 1 |
Tanaka, S | 1 |
Iwamoto, M | 1 |
Kimura, K | 1 |
Takahashi, Y | 1 |
Fujioka, H | 1 |
Sato, N | 1 |
Terasawa, R | 1 |
Kawaguchi, K | 1 |
Ikari, A | 1 |
Tominaga, T | 1 |
Maezawa, S | 1 |
Umezaki, N | 1 |
Matsuda, J | 1 |
Uchiyama, K | 1 |
Isa, T | 1 |
Kaneshiro, T | 1 |
Yamamoto, H | 1 |
Nakachi, A | 1 |
Teruya, T | 1 |
Shiroma, H | 1 |
Arakaki, K | 1 |
Nishimaki, T | 1 |
Kao, PS | 1 |
Chang, SC | 1 |
Wang, LW | 1 |
Lee, RC | 1 |
Liang, WY | 1 |
Lin, TC | 1 |
Chen, WS | 1 |
Jiang, JK | 1 |
Yang, SH | 1 |
Wang, HS | 1 |
Lin, JK | 1 |
Satoh, M | 1 |
Nakano, O | 1 |
Kuwahara, M | 1 |
Ito, A | 1 |
Arai, Y | 1 |
Al-Ahmadi, W | 1 |
Al-Ghamdi, M | 1 |
Al-Souhibani, N | 1 |
Khabar, KS | 1 |
Feliu, J | 1 |
Mel, R | 1 |
Borrega, P | 1 |
López Gómez, L | 1 |
Escudero, P | 1 |
Dorta, J | 1 |
Castro, J | 1 |
Vázquez-Estévez, SE | 1 |
Bolaños, M | 1 |
Espinosa, E | 1 |
González Barón, M | 1 |
Nakayama, H | 1 |
Aoki, N | 1 |
Hayashi, S | 1 |
Wakabayashi, K | 1 |
Karube, H | 1 |
Ogame, H | 1 |
Aoki, H | 1 |
Sakamoto, N | 1 |
Masuda, H | 1 |
Hemmi, A | 1 |
Kamoshida, S | 1 |
Matsuoka, H | 1 |
Ishikawa, T | 1 |
Maeda, K | 1 |
Shimomura, R | 1 |
Tsutsumi, Y | 1 |
Ogata, Y | 1 |
Matono, K | 1 |
Sasatomi, T | 1 |
Ishibashi, N | 1 |
Ohkita, A | 1 |
Mizobe, T | 1 |
Ogo, S | 1 |
Ikeda, S | 1 |
Ozasa, H | 1 |
Shirouzu, K | 1 |
Tsuji, K | 1 |
Honda, S | 1 |
Yamasaki, N | 1 |
Hiramatsu, K | 1 |
Kato, K | 1 |
Hirata, A | 1 |
Matsuba, H | 1 |
Hara, T | 1 |
Miyata, T | 1 |
Akagawa, T | 1 |
Kutsuna, Y | 1 |
Machiki, Y | 1 |
Fujioka, S | 1 |
Toyooka, M | 1 |
Shoji, Y | 1 |
Rivera, F | 1 |
Vega-Villegas, ME | 1 |
López-Brea, M | 1 |
Isla, D | 1 |
Mayorga, M | 1 |
Galdós, P | 1 |
Rubio, A | 1 |
Del Valle, A | 1 |
García-Reija, F | 1 |
García-Montesinos, B | 1 |
Rodríguez-Iglesias, J | 1 |
Mayordomo, J | 1 |
Rama, J | 1 |
Saiz-Bustillo, R | 1 |
Sanz-Ortiz, J | 1 |
Masuyama, K | 1 |
Oonishi, Y | 1 |
Sawataishi, M | 1 |
Suzuki, S | 1 |
Yamazaki, K | 1 |
Ishizawa, S | 1 |
Wakaki, K | 1 |
Ohkawa, S | 1 |
Itoh, Y | 1 |
Tamai, S | 1 |
Tarao, K | 1 |
Yamamoto, S | 1 |
Hirata, T | 1 |
Yamagishi, S | 1 |
Hirano, S | 1 |
Kutsukata, N | 1 |
Masuda, S | 1 |
Hisayoshi, T | 1 |
Hioki, M | 1 |
Choi, S | 1 |
Okada, F | 1 |
Kobayashi, M | 1 |
Habelhah, H | 1 |
Nakae, D | 1 |
Konishi, Y | 1 |
Totsuka, Y | 1 |
Hosokawa, M | 1 |
Maeda, O | 1 |
Iwase, H | 1 |
Mamiya, N | 1 |
Nakamura, M | 1 |
Mizuno, T | 1 |
Nishio, Y | 1 |
Ando, T | 1 |
Ina, K | 1 |
Kusugami, K | 1 |
Tokunaga, Y | 1 |
Kitaoka, A | 1 |
Yagi, T | 1 |
Tokuka, A | 1 |
Ohsumi, K | 1 |
Liu, J | 1 |
Ikeguchi, M | 1 |
Nakamura, S | 1 |
Kaibara, N | 1 |
Hayashi, J | 1 |
Hidaka, N | 1 |
Sanda, M | 1 |
Ohashi, N | 1 |
Yajima, Y | 1 |
Furukawa, Y | 1 |
Kato, M | 1 |
Nakanishi, T | 1 |
Nishikawa, M | 1 |
Nagase, T | 1 |
Nakagawa, C | 1 |
Maeda, S | 1 |
Kuroda, K | 1 |
Tokunaga, K | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Adjuvant Chemotherapy Versus Observation in Fully Resected Stage I Lung Adenocarcinoma With High Risk of Post-operative Recurrence[NCT03380468] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2018-01-01 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 trials available for uracil and Invasiveness, Neoplasm
Article | Year |
---|---|
A single-arm, phase 2 study of adjuvant chemotherapy with oral tegafur-uracil for pathologically lymphovascular invasion positive stage IA non-small cell lung cancer: LOGIK0602 study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Vessels; Carcinoma, Non-Small-Cell Lung; | 2020 |
Randomized phase II study of anastrozole plus tegafur-uracil as neoadjuvant therapy for ER-positive breast cancer in postmenopausal Japanese women (Neo-ACET BC).
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas | 2018 |
A Phase II Study of Adjuvant Chemotherapy of Tegafur-Uracil for Patients with Breast Cancer with HER2-negative Pathologic Residual Invasive Disease After Neoadjuvant Chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvan | 2016 |
Phase II study of a fixed dose-rate infusion of gemcitabine associated with uracil/tegafur in advanced carcinoma of the pancreas.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Deoxycy | 2002 |
Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Su | 2008 |
25 other studies available for uracil and Invasiveness, Neoplasm
Article | Year |
---|---|
Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cycloph | 2019 |
1-calcium phosphate-uracil inhibits intraperitoneal metastasis by suppressing FAK in epithelial ovarian cancer.
Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Adhesion; Cell Line, Tumor; Female; Focal Adhesion Kina | 2019 |
Repeat hepatectomy for intrahepatic recurrence of cholangiolocellular carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; | 2013 |
Inferior oncological prognosis of surgery without oral chemotherapy for stage III colon cancer in clinical settings.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2014 |
1‑calcium phosphate‑uracil, a synthesized pyrimidine derivative agent, has anti‑proliferative, pro‑apoptotic and anti‑invasion effects on multiple tumor cell lines.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screenin | 2014 |
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape | 2016 |
[Case of esophageal cancer successfully performed in early response evaluation for preoperative chemotherapy by FDG-PET].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci | 2008 |
The impact of preoperative chemoradiotherapy on advanced low rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Combined Modal | 2010 |
[A case of marked efficacy of low-dose UFT against metastatic bladder cancer].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female | 2011 |
miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer.
Topics: Adenine; Animals; Breast Neoplasms; ELAV Proteins; Female; Fibroblasts; Gene Expression Regulation, | 2013 |
[A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma].
Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoembryo | 2004 |
Immunohistochemical evaluation of thymidylate synthase (TS) and p16INK4a in advanced colorectal cancer: implication of TS expression in 5-FU-based adjuvant chemotherapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Chemotherapy, Adjuvant; Colonic Neoplasms; C | 2004 |
The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo | 2006 |
Stage IA non-small cell lung cancer: vessel invasion is a poor prognostic factor and a new target of adjuvant chemotherapy.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; | 2007 |
[A resected case of squamous cell carcinoma of the breast successfully treated by FU plus cisplatin (CDDP) adjuvant therapy against recurrent metastases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Squamous Cell; C | 2007 |
[A case of effective regimen of tegafur and uracil (UFT)/leucovorin (LV) plus irinotecan (CPT-11) for advanced rectal carcinoma with severe pelvic infiltration to be performed curative resection].
Topics: Adenocarcinoma; Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Pr | 2007 |
[A case of small cell carcinoma of the stomach with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chemotherapy, Adjuvant; | 1994 |
[A case of hepatocellular carcinoma with portal invasion and right adrenal gland metastasis showing marked contraction of primary tumor and metastasis with treated by UFT alone].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocell | 1994 |
[A case of far-advanced gastric cancer treated with neoadjuvant combination chemotherapy of UFT, low-dose CDDP and leucovorin, followed by subtotal gastrectomy with curative intent].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Chemotherapy, Adjuvant; C | 1997 |
Single treatment with cisplatin or UFT, but not their combination treatment enhances the metastatic capacity of mouse fibrosarcoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemotaxis; Cisplatin; Clone Cells; Drug Co | 1999 |
Scirrhous cancer of the stomach which survived for more than five years after neoadjuvant chemotherapy with UFT (uracil and tegafur) and cisplatin.
Topics: Adenocarcinoma, Scirrhous; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuv | 2000 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for stages 3 and 4 gastric carcinoma: A preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administration Sc | 2000 |
Re-expression of the cadherin-catenin complex in lymph nodes with metastasis in advanced gastric cancer: the relationship with patient survival.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; alpha Catenin; Antineoplastic Combined Chemotherapy | 2002 |
[A effective combination preoperative intraarterial infusion chemotherapy and irradiation for advanced sigmoid colon cancer with bladder invasion].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Combined Modality | 1992 |
[A case of hepatocellular carcinoma with extrahepatic portal vein obstruction due to tumor invasion, responsive to oral administration of UFT].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellul | 1987 |