Page last updated: 2024-10-20

uracil and Gestational Trophoblastic Disease

uracil has been researched along with Gestational Trophoblastic Disease in 1 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Gestational Trophoblastic Disease: A group of diseases arising from pregnancy that are commonly associated with hyperplasia of trophoblasts (TROPHOBLAST) and markedly elevated human CHORIONIC GONADOTROPIN. They include HYDATIDIFORM MOLE, invasive mole (HYDATIDIFORM MOLE, INVASIVE), placental-site trophoblastic tumor (TROPHOBLASTIC TUMOR, PLACENTAL SITE), and CHORIOCARCINOMA. These neoplasms have varying propensities for invasion and spread.

Research Excerpts

ExcerptRelevanceReference
" To determine the plasma dihydrouracil/uracil ratio (DUUR) as a potential index for setting 5-FU/FUDR doses, the authors conducted a prospective study on the relationships of the DUUR with 5-FU/FUDR pharmacokinetic and pharmacodynamic parameters."2.71Important role of the dihydrouracil/uracil ratio in marked interpatient variations of fluoropyrimidine pharmacokinetics and pharmacodynamics. ( Hu, P; Jiang, H; Jiang, J; Lu, J, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, H1
Lu, J1
Jiang, J1
Hu, P1

Trials

1 trial available for uracil and Gestational Trophoblastic Disease

ArticleYear
Important role of the dihydrouracil/uracil ratio in marked interpatient variations of fluoropyrimidine pharmacokinetics and pharmacodynamics.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:11

    Topics: Adult; Antimetabolites, Antineoplastic; Chorionic Gonadotropin; Female; Floxuridine; Fluorouracil; G

2004