Page last updated: 2024-10-20

uracil and DDPAC

uracil has been researched along with DDPAC in 10 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
"The prospective, multicenter, noninterventional TACTIC study assessed effectiveness and safety of trifluridine/tipiracil (FTD/TPI) in patients with metastatic colorectal cancer (mCRC) in a real-world setting in Germany, thus evaluating the external validity of the findings from the pivotal RECOURSE trial."8.31Effectiveness, safety and quality of life of trifluridine/tipiracil in pretreated patients with metastatic colorectal cancer: Real-world data from the noninterventional TACTIC study in Germany. ( Bruch, HR; de Buhr, R; Decker, T; Frank, M; Göhler, T; Grundeis, M; Grunewald, R; Harich, HD; Hartmann, F; Hogrefe, C; Kojouharoff, G; Kröning, H; Liersch, R; Lipke, J; Marschner, N; Moorahrend, E; Nusch, A; Potthoff, K; Reisländer, T; Sauer, A; Schwaner, I; Semsek, D; Stephany, M; Uhlig, J; Vehling-Kaiser, U; Welslau, M, 2023)
"Trifluridine/tipiracil (FTD/TPI) and regorafenib (REG) are standard therapies for refractory metastatic colorectal cancer (mCRC)."8.31Real-world evidence of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer using an administrative claims database in Japan. ( Kagawa, Y; Kunitomi, Y; Nakashima, M; Okude, R; Shinozaki, E; Tone, T, 2023)
"Regorafenib (R) and trifluridine/tipiracil (FTD/TPI) are of proven efficacy in metastatic colorectal cancer (mCRC) patient's refractory to standard therapies."8.12Sequential Treatment With Trifluridine/Tipiracil and Regorafenib in Refractory Metastatic Colorectal Cancer Patients: An AGEO Prospective "Real-World Study". ( Artru, P; Bouché, O; Coriat, R; Coutzac, C; De La Fouchardière, C; Doat, S; Gallois, C; Henriques, J; Masson, T; Moulin, V; Saint, A; Taieb, J; Tougeron, D; Trouilloud, I; Vernerey, D, 2022)
"Colorectal cancer is a disease of older patients, but few guidelines directly address age in their recommendations."7.01Trifluridine/tipiracil (FTD/TPI) and regorafenib in older patients with metastatic colorectal cancer. ( Araujo, KB; Festa, J; Mardegan, L; Meton, F; Piranda, DN; Victorino, APOS, 2023)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"The prospective, multicenter, noninterventional TACTIC study assessed effectiveness and safety of trifluridine/tipiracil (FTD/TPI) in patients with metastatic colorectal cancer (mCRC) in a real-world setting in Germany, thus evaluating the external validity of the findings from the pivotal RECOURSE trial."4.31Effectiveness, safety and quality of life of trifluridine/tipiracil in pretreated patients with metastatic colorectal cancer: Real-world data from the noninterventional TACTIC study in Germany. ( Bruch, HR; de Buhr, R; Decker, T; Frank, M; Göhler, T; Grundeis, M; Grunewald, R; Harich, HD; Hartmann, F; Hogrefe, C; Kojouharoff, G; Kröning, H; Liersch, R; Lipke, J; Marschner, N; Moorahrend, E; Nusch, A; Potthoff, K; Reisländer, T; Sauer, A; Schwaner, I; Semsek, D; Stephany, M; Uhlig, J; Vehling-Kaiser, U; Welslau, M, 2023)
"Trifluridine/tipiracil (FTD/TPI) and regorafenib (REG) are standard therapies for refractory metastatic colorectal cancer (mCRC)."4.31Real-world evidence of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer using an administrative claims database in Japan. ( Kagawa, Y; Kunitomi, Y; Nakashima, M; Okude, R; Shinozaki, E; Tone, T, 2023)
"Regorafenib (R) and trifluridine/tipiracil (FTD/TPI) are of proven efficacy in metastatic colorectal cancer (mCRC) patient's refractory to standard therapies."4.12Sequential Treatment With Trifluridine/Tipiracil and Regorafenib in Refractory Metastatic Colorectal Cancer Patients: An AGEO Prospective "Real-World Study". ( Artru, P; Bouché, O; Coriat, R; Coutzac, C; De La Fouchardière, C; Doat, S; Gallois, C; Henriques, J; Masson, T; Moulin, V; Saint, A; Taieb, J; Tougeron, D; Trouilloud, I; Vernerey, D, 2022)
"Colorectal cancer is a disease of older patients, but few guidelines directly address age in their recommendations."3.01Trifluridine/tipiracil (FTD/TPI) and regorafenib in older patients with metastatic colorectal cancer. ( Araujo, KB; Festa, J; Mardegan, L; Meton, F; Piranda, DN; Victorino, APOS, 2023)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's10 (100.00)2.80

Authors

AuthorsStudies
Coutzac, C1
Trouilloud, I1
Artru, P1
Henriques, J1
Masson, T1
Doat, S1
Bouché, O1
Coriat, R1
Saint, A1
Moulin, V1
Vernerey, D1
Gallois, C1
De La Fouchardière, C1
Tougeron, D1
Taieb, J1
Yoshino, T4
Van Cutsem, E4
Li, J1
Shen, L1
Kim, TW1
Sriuranpong, V1
Xuereb, L1
Aubel, P1
Fougeray, R1
Cattan, V1
Amellal, N1
Ohtsu, A4
Mayer, RJ1
Hochster, H3
Shitara, K3
Mayer, R3
Falcone, A3
Doi, T3
Ilson, DH3
Arkenau, HT3
George, B3
Benhadji, KA3
Makris, L3
Tabernero, J3
Ding, PQ1
Dolley, A1
Cheung, WY1
Victorino, APOS1
Meton, F1
Mardegan, L1
Festa, J1
Piranda, DN1
Araujo, KB1
Hayashi, K1
Furuta, M1
Furusawa, K1
Hamaguchi, T1
Watanabe, M1
Inokuchi, Y1
Onuma, S1
Hashimoto, I1
Suematsu, H1
Nagasawa, S1
Kanematsu, K1
Yamada, T1
Notsu, A1
Ogata, T1
Oshima, T1
Machida, N1
Furuse, J1
Maeda, S1
Kröning, H1
Göhler, T1
Decker, T1
Grundeis, M1
Kojouharoff, G1
Lipke, J1
Semsek, D1
Moorahrend, E1
Sauer, A1
Bruch, HR1
Liersch, R1
Nusch, A1
Vehling-Kaiser, U1
Welslau, M1
Grunewald, R1
Harich, HD1
Stephany, M1
Uhlig, J1
de Buhr, R1
Frank, M1
Hogrefe, C1
Marschner, N1
Potthoff, K1
Hartmann, F1
Reisländer, T1
Schwaner, I1
Kagawa, Y1
Shinozaki, E1
Okude, R1
Tone, T1
Kunitomi, Y1
Nakashima, M1
Shiroyama, M1
Fukuoka, S1
Masuishi, T1
Takashima, A1
Kumekawa, Y1
Kajiwara, T1
Yamazaki, K1
Shimada, Y1
Esaki, T1
Makiyama, A1
Moriwaki, T1

Reviews

3 reviews available for uracil and DDPAC

ArticleYear
Effect of KRAS codon 12 or 13 mutations on survival with trifluridine/tipiracil in pretreated metastatic colorectal cancer: a meta-analysis.
    ESMO open, 2022, Volume: 7, Issue:3

    Topics: Codon; Colonic Neoplasms; Colorectal Neoplasms; Frontotemporal Dementia; Humans; Mutation; Proto-Onc

2022
Trifluridine/tipiracil (FTD/TPI) and regorafenib in older patients with metastatic colorectal cancer.
    Journal of geriatric oncology, 2023, Volume: 14, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Front

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Trials

2 trials available for uracil and DDPAC

ArticleYear
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer.
    ESMO open, 2022, Volume: 7, Issue:6

    Topics: Adult; Colonic Neoplasms; Colorectal Neoplasms; Esophagogastric Junction; Frontotemporal Dementia; H

2022
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer.
    ESMO open, 2022, Volume: 7, Issue:6

    Topics: Adult; Colonic Neoplasms; Colorectal Neoplasms; Esophagogastric Junction; Frontotemporal Dementia; H

2022
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer.
    ESMO open, 2022, Volume: 7, Issue:6

    Topics: Adult; Colonic Neoplasms; Colorectal Neoplasms; Esophagogastric Junction; Frontotemporal Dementia; H

2022
Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer.
    ESMO open, 2022, Volume: 7, Issue:6

    Topics: Adult; Colonic Neoplasms; Colorectal Neoplasms; Esophagogastric Junction; Frontotemporal Dementia; H

2022
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

6 other studies available for uracil and DDPAC

ArticleYear
Sequential Treatment With Trifluridine/Tipiracil and Regorafenib in Refractory Metastatic Colorectal Cancer Patients: An AGEO Prospective "Real-World Study".
    Clinical colorectal cancer, 2022, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combin

2022
Trifluridine/Tipiracil in the Real-World Management of Metastatic Gastric and Gastroesophageal Junction Cancers in Canada.
    Current oncology (Toronto, Ont.), 2022, 12-22, Volume: 30, Issue:1

    Topics: Adult; Aged; Canada; Colorectal Neoplasms; Esophageal Neoplasms; Esophagogastric Junction; Frontotem

2022
Evaluation of Irinotecan and Trifluridine/Tipiracil as Fourth-line Treatments After Third-line Nivolumab for Advanced Gastric Cancer.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Combinations; Frontotempo

2023
Effectiveness, safety and quality of life of trifluridine/tipiracil in pretreated patients with metastatic colorectal cancer: Real-world data from the noninterventional TACTIC study in Germany.
    International journal of cancer, 2023, 09-15, Volume: 153, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combin

2023
Real-world evidence of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer using an administrative claims database in Japan.
    ESMO open, 2023, Volume: 8, Issue:4

    Topics: Bevacizumab; Colonic Neoplasms; Colorectal Neoplasms; Frontotemporal Dementia; Humans; Japan; Retros

2023
Renal impairment as a risk factor for trifluridine/tipiracil-induced adverse events in metastatic colorectal cancer patients from the REGOTAS study.
    Scientific reports, 2023, 10-20, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Drug Combin

2023