Page last updated: 2024-10-20

uracil and Chronic Kidney Diseases

uracil has been researched along with Chronic Kidney Diseases in 14 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
"Alogliptin improves steroid-induced hyperglycemia by decrease of glucagon levels through an increase in plasma GLP-1 levels."7.80Alogliptin improves steroid-induced hyperglycemia in treatment-naïve Japanese patients with chronic kidney disease by decrease of plasma glucagon levels. ( Fujigaki, Y; Fujikura, T; Isobe, S; Iwakura, T; Kato, A; Naito, Y; Ohashi, N; Ono, M; Sakao, Y; Tsuji, N; Tsuji, T; Yasuda, H, 2014)
"We conducted an observational prospective study, on 232 patients with chronic kidney disease, undergoing treatment with paritaprevir/ombitasvir/ritonavir and dasabuvir, for chronic hepatitis C infection - genotype 1b."3.96Safety and efficacy of direct-acting antivirals for chronic hepatitis C in patients with chronic kidney disease. ( Iliescu, EL; Mercan-Stanciu, A; Toma, L, 2020)
"Alogliptin improves steroid-induced hyperglycemia by decrease of glucagon levels through an increase in plasma GLP-1 levels."3.80Alogliptin improves steroid-induced hyperglycemia in treatment-naïve Japanese patients with chronic kidney disease by decrease of plasma glucagon levels. ( Fujigaki, Y; Fujikura, T; Isobe, S; Iwakura, T; Kato, A; Naito, Y; Ohashi, N; Ono, M; Sakao, Y; Tsuji, N; Tsuji, T; Yasuda, H, 2014)
"7%): 4 due to severe adverse events (including 3 deaths) and 1 patient´s decision."1.51Effectiveness, safety/tolerability of OBV/PTV/r ± DSV in patients with HCV genotype 1 or 4 with/without HIV-1 co-infection, chronic kidney disease (CKD) stage IIIb-V and dialysis in Spanish clinical practice - Vie-KinD study. ( Ahumada, A; Aldamiz-Echevarría, T; Baliellas, C; Barril, G; Benlloch, S; Bonet, L; Carmona, I; Castaño, MA; Castro, Á; de Álvaro, C; de Los Santos, I; Delgado, M; Devesa-Medina, MJ; García-Buey, L; García-Samaniego, J; Gea-Rodríguez, F; González-Parra, E; Gutiérrez, ML; Jiménez-Pérez, M; Laguno, M; Londoño, MC; Losa, JE; Mallolas, J; Manzanares, A; Martín-Granizo, I; Montero-Alonso, M; Montes, ML; Morán-Sánchez, S; Morano, L; Muñoz-Gómez, R; Navascués, CA; Polo-Lorduy, B; Riveiro-Barciela, M; Rivero, A; Roget, M; Serra, MÁ, 2019)
"In the interferon era, the treatment of hepatitis C virus (HCV) infection in patients on haemodialysis (HD) was limited due to the significant number of treatment-related adverse events (AEs)."1.51Elimination of hepatitis C virus infection from a hemodialysis unit and impact of treatment on the control of anemia. ( Arias, M; Belmar, L; González, LN; Laguno, M; Llovet, LP; Londoño, MC; Maduell, F; Mallolas, J; Martínez-Rebollar, M; Ojeda, R; Rodas, L; Rossi, F; Ugalde, J, 2019)
" RBV was dosed by physician discretion between 200 mg weekly and 200 mg daily."1.48High Efficacy of ombitasvir/paritaprevir/ritonavir plus dasabuvir in hepatitis C genotypes 4 and 1-infected patients with severe chronic kidney disease. ( Afghani, AA; Alghamdi, AS; Alghamdi, MN; AlMousa, A; Alswat, K; AlZanbagi, A; Aseeri, M; Assiri, AM; Babatin, MA; Sanai, FM, 2018)
"We recruited 36 CKD patients with type 2 diabetes."1.40Effects of alogliptin in chronic kidney disease patients with type 2 diabetes. ( Mugishima, K; Murasawa, T; Ohno, D; Otsuka, T; Otsuka, Y; Sakai, Y; Sumi, Y; Suzuki, A; Tsuruoka, S, 2014)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (92.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Londoño, MC2
Riveiro-Barciela, M1
Ahumada, A1
Muñoz-Gómez, R1
Roget, M1
Devesa-Medina, MJ1
Serra, MÁ1
Navascués, CA1
Baliellas, C1
Aldamiz-Echevarría, T1
Gutiérrez, ML1
Polo-Lorduy, B1
Carmona, I1
Benlloch, S1
Bonet, L1
García-Samaniego, J1
Jiménez-Pérez, M1
Morán-Sánchez, S1
Castro, Á1
Delgado, M1
Gea-Rodríguez, F1
Martín-Granizo, I1
Montes, ML1
Morano, L1
Castaño, MA1
de Los Santos, I1
Laguno, M2
Losa, JE1
Montero-Alonso, M1
Rivero, A1
de Álvaro, C1
Manzanares, A1
Mallolas, J2
Barril, G1
González-Parra, E1
García-Buey, L1
Wiegand, J1
Buggisch, P1
Mauss, S1
Boeker, KHW1
Klinker, H1
Müller, T1
Günther, R1
Serfert, Y1
Manns, MP1
Zeuzem, S1
Berg, T1
Hinrichsen, H1
C-Registry, GH1
Iliescu, EL1
Mercan-Stanciu, A1
Toma, L1
Sanai, FM1
Alghamdi, AS1
Afghani, AA1
Alswat, K1
AlZanbagi, A1
Alghamdi, MN1
AlMousa, A1
Aseeri, M1
Assiri, AM1
Babatin, MA1
Abdel-Razek, W1
Waked, I1
Maduell, F1
Belmar, L1
Ugalde, J1
Martínez-Rebollar, M1
Ojeda, R1
Arias, M1
Rodas, L1
Rossi, F1
Llovet, LP1
González, LN1
Fabrizi, F1
Negro, F1
Bondin, M1
Cacoub, P1
Örmeci, N1
Sezgin, O1
Karaali, R1
Aygen, B1
Turan, D1
Yaras, S1
Erdem, İ1
Yildiz, O1
Karakaya, F1
Ateş, K1
Asiller, ÖÖ1
Charbonnel, B1
Schweizer, A1
Dejager, S1
Nakamura, Y1
Inagaki, M1
Shimizu, T1
Fujita, K1
Inoue, M1
Gotoh, H1
Oguchi, K1
Goto, Y1
Sakai, Y1
Suzuki, A1
Mugishima, K1
Sumi, Y1
Otsuka, Y1
Otsuka, T1
Ohno, D1
Murasawa, T1
Tsuruoka, S1
Ohashi, N1
Tsuji, N1
Naito, Y1
Iwakura, T1
Isobe, S1
Ono, M1
Fujikura, T1
Tsuji, T1
Sakao, Y1
Yasuda, H1
Kato, A1
Fujigaki, Y1
Uchida, T1
Oda, T1
Matsubara, H1
Watanabe, A1
Takechi, H1
Oshima, N1
Sakurai, Y1
Kumagai, H1
Flynn, C1
Bakris, GL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Occult Hepatitis C Virus Infection In Hemodialysis Patients Who Achieved A Sustained Virological Response To Directly Acting Antiviral Drugs: Is It A Concern ?[NCT04719338]30 participants (Actual)Interventional2021-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for uracil and Chronic Kidney Diseases

ArticleYear
Expert opinion on the management of renal manifestations of chronic HCV infection.
    Antiviral therapy, 2018, Volume: 23, Issue:Suppl 2

    Topics: 2-Naphthylamine; Amides; Aminoisobutyric Acids; Anilides; Antiviral Agents; Benzimidazoles; Benzofur

2018
Combination therapy with DPP-4 inhibitors and insulin in patients with type 2 diabetes mellitus: what is the evidence?
    Hospital practice (1995), 2013, Volume: 41, Issue:2

    Topics: Adamantane; Body Weight; Diabetes Complications; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-P

2013
Noninsulin glucose-lowering agents for the treatment of patients on dialysis.
    Nature reviews. Nephrology, 2013, Volume: 9, Issue:3

    Topics: Adamantane; Biguanides; Diabetic Nephropathies; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Dise

2013

Trials

1 trial available for uracil and Chronic Kidney Diseases

ArticleYear
Long-term effects of alogliptin benzoate in hemodialysis patients with diabetes: a 2-year study.
    Nephron. Clinical practice, 2013, Volume: 123, Issue:1-2

    Topics: Comorbidity; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug-Related Side Effect

2013

Other Studies

10 other studies available for uracil and Chronic Kidney Diseases

ArticleYear
Effectiveness, safety/tolerability of OBV/PTV/r ± DSV in patients with HCV genotype 1 or 4 with/without HIV-1 co-infection, chronic kidney disease (CKD) stage IIIb-V and dialysis in Spanish clinical practice - Vie-KinD study.
    PloS one, 2019, Volume: 14, Issue:9

    Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Coinfection; Cyclopropanes; Drug Ther

2019
Hepatitis C therapy with direct antiviral agents in patients with advanced chronic kidney disease: real-world experience of the German Hepatitis C-Registry (Deutsches Hepatitis C-Register).
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:11

    Topics: 2-Naphthylamine; Acute Disease; Adult; Aged; Anemia; Anilides; Antiviral Agents; Benzimidazoles; Car

2019
Safety and efficacy of direct-acting antivirals for chronic hepatitis C in patients with chronic kidney disease.
    BMC nephrology, 2020, 01-16, Volume: 21, Issue:1

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Cryoglobulinemia; Cyclopropanes; Drug Thera

2020
High Efficacy of ombitasvir/paritaprevir/ritonavir plus dasabuvir in hepatitis C genotypes 4 and 1-infected patients with severe chronic kidney disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:8

    Topics: 2-Naphthylamine; Adult; Anilides; Antiviral Agents; Carbamates; Cohort Studies; Cyclopropanes; Drug

2018
Editorial: is sofosbuvir-based therapy suitable for patients with advanced chronic kidney disease?
    Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:3

    Topics: 2-Naphthylamine; Anilides; Benzimidazoles; Carbamates; Cyclopropanes; Fluorenes; Humans; Lactams, Ma

2018
Elimination of hepatitis C virus infection from a hemodialysis unit and impact of treatment on the control of anemia.
    Gastroenterologia y hepatologia, 2019, Volume: 42, Issue:3

    Topics: 2-Naphthylamine; Anemia; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Darbepoetin alfa; Fe

2019
Effectiveness of fixed-dose combination of paritaprevir, ritonavir, ombitasvir, and dasabuvir in patients with chronic hepatitis C virus infection and chronic kidney diseases: real-life experiences.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:4

    Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Carbamates; Cyclopropan

2019
Effects of alogliptin in chronic kidney disease patients with type 2 diabetes.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:3

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypo

2014
Alogliptin improves steroid-induced hyperglycemia in treatment-naïve Japanese patients with chronic kidney disease by decrease of plasma glucagon levels.
    Medical science monitor : international medical journal of experimental and clinical research, 2014, Apr-10, Volume: 20

    Topics: Aged; Asian People; Body Mass Index; Female; Glucagon; Glucagon-Like Peptide 1; Glycated Hemoglobin;

2014
Renoprotective effects of a dipeptidyl peptidase 4 inhibitor in a mouse model of progressive renal fibrosis.
    Renal failure, 2017, Volume: 39, Issue:1

    Topics: Actins; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Urea Nitrogen; Calci

2017