uracil and Chromosome-Defective Micronuclei studies

uracil and Chromosome-Defective Micronuclei

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

Excerpt	Relevance	Reference
" The obtained results indicate that CYN is able to exert a wide range of adverse effects, including oxidative stress and genotoxicity in fish leucocytes."	1.42	Cylindrospermopsin induces oxidative stress and genotoxic effects in the fish CLC cell line. ( Rymuszka, A; Sieroslawska, A, 2015)
"5-fluorouracil induced an increase in micronucleus frequency, which could significantly be enhanced by the concurrent application of 2,6-dihydroxypyridine, an inhibitor of dihydropyrimidine dehydrogenase."	1.29	Combination of the chemotherapeutic agent 5-fluorouracil with an inhibitor of its catabolism results in increased micronucleus induction. ( Kühnel, A; Podschun, B; Stopper, H, 1994)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Sieroslawska, A	1
Rymuszka, A	1
Stopper, H	1
Kühnel, A	1
Podschun, B	1
Humpage, AR	1
Fenech, M	1
Thomas, P	1
Falconer, IR	1

Studies

Sieroslawska, A

Rymuszka, A

Stopper, H

Kühnel, A

Podschun, B

Humpage, AR

Fenech, M

Thomas, P

Falconer, IR

Other Studies

3 other studies available for uracil and Chromosome-Defective Micronuclei

Article	Year
Cylindrospermopsin induces oxidative stress and genotoxic effects in the fish CLC cell line. Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:4 Topics: Adenosine Triphosphate; Alkaloids; Animals; Bacterial Toxins; Carps; Cell Line; Cell Membrane; Cell	2015
Combination of the chemotherapeutic agent 5-fluorouracil with an inhibitor of its catabolism results in increased micronucleus induction. Biochemical and biophysical research communications, 1994, Sep-15, Volume: 203, Issue:2 Topics: Animals; Binding Sites; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Kinetics; L Cells; Liver;	1994
Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutation research, 2000, Dec-20, Volume: 472, Issue:1-2 Topics: Alkaloids; Bacterial Toxins; Cell Line, Transformed; Centromere; Cyanobacteria; Cyanobacteria Toxins	2000

Article

Year

Cylindrospermopsin induces oxidative stress and genotoxic effects in the fish CLC cell line.

Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:4

Topics: Adenosine Triphosphate; Alkaloids; Animals; Bacterial Toxins; Carps; Cell Line; Cell Membrane; Cell

2015

Combination of the chemotherapeutic agent 5-fluorouracil with an inhibitor of its catabolism results in increased micronucleus induction.

Biochemical and biophysical research communications, 1994, Sep-15, Volume: 203, Issue:2

Topics: Animals; Binding Sites; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Kinetics; L Cells; Liver;

1994

Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin.

Mutation research, 2000, Dec-20, Volume: 472, Issue:1-2

Topics: Alkaloids; Bacterial Toxins; Cell Line, Transformed; Centromere; Cyanobacteria; Cyanobacteria Toxins

2000