uracil has been researched along with Cell Transformation, Neoplastic in 17 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "More than 50% of colon cancer-associated mutations in the p53 tumor suppressor gene are C-->T transitions." | 2.41 | Thymine DNA glycosylase. ( Bentele, M; Hardeland, U; Jiricny, J; Lettieri, T; Schär, P; Steinacher, R, 2001) |
| "The mutations found in murine tumors are similar to those found in human skin cancers, and PMA promotes proliferation of human skin cells." | 1.51 | A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils. ( Bhagwat, AS; Perera, MLW; Senevirathne, V; Siriwardena, SU; Stewart, J, 2019) |
| "Uridine is a natural nucleoside precursor of uridine monophosphate in organisms and thus is considered to be safe and is used in a wide range of clinical settings." | 1.43 | Uridine homeostatic disorder leads to DNA damage and tumorigenesis. ( Cai, C; Cao, D; Cao, Z; Chen, X; Huang, D; Ma, J; Zhang, X; Zhou, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Basbous, J | 1 |
| Aze, A | 1 |
| Chaloin, L | 1 |
| Lebdy, R | 1 |
| Hodroj, D | 1 |
| Ribeyre, C | 1 |
| Larroque, M | 1 |
| Shepard, C | 1 |
| Kim, B | 1 |
| Pruvost, A | 1 |
| Moreaux, J | 1 |
| Maiorano, D | 1 |
| Mechali, M | 1 |
| Constantinou, A | 1 |
| Siriwardena, SU | 1 |
| Perera, MLW | 1 |
| Senevirathne, V | 1 |
| Stewart, J | 1 |
| Bhagwat, AS | 1 |
| Cao, Z | 1 |
| Ma, J | 1 |
| Chen, X | 1 |
| Zhou, B | 1 |
| Cai, C | 1 |
| Huang, D | 1 |
| Zhang, X | 1 |
| Cao, D | 1 |
| Maire, MA | 1 |
| Bazin, E | 1 |
| Fessard, V | 1 |
| Rast, C | 1 |
| Humpage, AR | 1 |
| Vasseur, P | 1 |
| Le Floch, R | 1 |
| Chiche, J | 1 |
| Marchiq, I | 1 |
| Naiken, T | 2 |
| Ilc, K | 1 |
| Ilk, K | 1 |
| Murray, CM | 1 |
| Critchlow, SE | 1 |
| Roux, D | 1 |
| Simon, MP | 1 |
| Pouysségur, J | 1 |
| Ihlaseh, SM | 1 |
| de Oliveira, ML | 1 |
| Teràn, E | 1 |
| de Camargo, JL | 1 |
| Barbisan, LF | 1 |
| Lang, T | 1 |
| Dalal, S | 1 |
| Chikova, A | 1 |
| DiMaio, D | 1 |
| Sweasy, JB | 1 |
| Ishiwata, K | 1 |
| Oikawa, A | 1 |
| Shibata, MA | 1 |
| Sano, M | 1 |
| Hagiwara, A | 1 |
| Hasegawa, R | 1 |
| Shirai, T | 1 |
| Lina, BA | 1 |
| Rutten, AA | 1 |
| Woutersen, RA | 1 |
| Melnyk, S | 1 |
| Pogribna, M | 1 |
| Miller, BJ | 1 |
| Basnakian, AG | 1 |
| Pogribny, IP | 1 |
| James, SJ | 1 |
| Hardeland, U | 1 |
| Bentele, M | 1 |
| Lettieri, T | 1 |
| Steinacher, R | 1 |
| Jiricny, J | 1 |
| Schär, P | 1 |
| Watkins, JF | 1 |
| Kuwano, M | 2 |
| Koga, M | 1 |
| Matsui, K | 1 |
| Endo, H | 2 |
| Fidler, IJ | 1 |
| Lieber, S | 1 |
| Akiyama, S | 1 |
| Kohga, M | 1 |
| Heidelberger, C | 1 |
2 reviews available for uracil and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Thymine DNA glycosylase.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Base Pair Mismatch; Base Sequence; Cell Transforma | 2001 |
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Divisi | 1970 |
15 other studies available for uracil and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; DNA Replication; H | 2020 |
A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils.
Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cytidine Deaminase; Cytosine; DNA, Single-S | 2019 |
Uridine homeostatic disorder leads to DNA damage and tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; DNA Damage; Dose-Response Relationship, Drug; Genotype; Ho | 2016 |
Morphological cell transformation of Syrian hamster embryo (SHE) cells by the cyanotoxin, cylindrospermopsin.
Topics: Alkaloids; Animals; Bacterial Toxins; Biotransformation; Carcinogenicity Tests; Carcinogens; Cell Li | 2010 |
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
Topics: Basigin; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; DNA Primers; Flow Cy | 2011 |
Chemopreventive property of dietary ginger in rat urinary bladder chemical carcinogenesis.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Cell Proliferation; Cell Transformation, Neoplasti | 2006 |
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
Topics: Animals; Cell Transformation, Neoplastic; DNA Polymerase beta; DNA Primers; DNA Repair; Embryo, Mamm | 2007 |
Chromatin structure interferes with excision of abnormal bases from DNA.
Topics: Cell Line; Cell Transformation, Neoplastic; Chromatin; DNA; DNA Glycosylases; DNA Repair; Female; He | 1982 |
Modification by analgesics of lesion development in the urinary tract and various other organs of rats pretreated with dihydroxy-di-N-propylnitrosamine and uracil.
Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Carcinogens; Cell Transformation, Neoplastic; Male; | 1995 |
Effect of coffee drinking on cell proliferation in rat urinary bladder epithelium.
Topics: Animals; Body Weight; Cell Division; Cell Transformation, Neoplastic; Coffee; Drinking; Electrolytes | 1993 |
Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.
Topics: Animals; Aspartic Acid; Cell Death; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Crice | 1999 |
Studies on a virogenic clone of SV 40-transformed rabbit cells using cell fusion and in situ hybridization.
Topics: Animals; Antigens, Viral; Autoradiography; Cell Fusion; Cell Transformation, Neoplastic; Cells, Cult | 1973 |
Synergistic effect of fusidic acid with polymyxin-B and amphotericin-B on transformed and normal fibroblastic cells.
Topics: Amphotericin B; Animals; Carbon Radioisotopes; Cell Line; Cell Survival; Cell Transformation, Neopla | 1973 |
Quantitative analysis of the mechanism of glucocorticoid enhancement of experimental metastasis.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Glucocorticoids; Iodine Isotopes; Lung; L | 1972 |
Potentiation of fusidic acid and lentinan effects upon normal and transformed fibroblastic cells by amphotericin B.
Topics: Amphotericin B; Animals; Animals, Newborn; Antineoplastic Agents; Carbon Isotopes; Cell Survival; Ce | 1972 |