uracil has been researched along with Carcinoma, Non-Small Cell Lung in 81 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
| Excerpt | Relevance | Reference |
|---|---|---|
| "We randomly assigned patients with completely resected pathological stage I adenocarcinoma of the lung to receive either oral uracil-tegafur (250 mg of tegafur per square meter of body-surface area per day) for two years or no treatment." | 9.11 | A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. ( Hamajima, N; Hata, E; Ichinose, Y; Kato, H; Ohta, M; Tada, H; Tsuboi, M; Tsubota, N; Wada, H; Watanabe, Y, 2004) |
| "We randomly assigned patients with completely resected pathological stage I adenocarcinoma of the lung to receive either oral uracil-tegafur (250 mg of tegafur per square meter of body-surface area per day) for two years or no treatment." | 5.11 | A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. ( Hamajima, N; Hata, E; Ichinose, Y; Kato, H; Ohta, M; Tada, H; Tsuboi, M; Tsubota, N; Wada, H; Watanabe, Y, 2004) |
| " On the other hand, uracil-tegafur was also shown to improve survival among patients with stage I adenocarcinoma in Japan." | 4.83 | [Adjuvant chemotherapy for non-small cell lung cancer]. ( Ichinose, Y; Okamoto, T, 2006) |
| " Actually, the EGFR tyrosine kinase inhibitor, gefitinib, is well known to be significantly effective for oriental people, including Japanese, female, adenocarcinoma and never-smoker, suggesting an inherited difference." | 3.74 | [Differences in the therapeutic strategies for lung cancer between Europe/United States and Japan]. ( Hanibuchi, M; Sone, S; Tomimoto, H; Yano, S, 2007) |
| "A phase II evaluation of UFT, a mixture of tegafur and uracil, was performed in 13 patients with non-small cell lung cancer (eight patients with adenocarcinoma and five patients with squamous cell carcinoma)." | 3.67 | [A phase II study of UFT in non-small cell lung cancer]. ( Hojo, F; Inoue, I; Kimura, K; Nakamura, Y; Nakanishi, S; Noda, Y; Shimizu, E; Sone, S; Yagi, M; Yamasaki, K, 1986) |
| "Etoposide 50 mg/m(2), UFT 250 mg/m(2) and leucovorin 90 mg (fixed dose) were dosed in 3 gifts approximately 8h apart for 14 days followed by 1 week rest every 3 weeks until progressive disease (PD)." | 2.74 | Oral UFT, etoposide and leucovorin in recurrent non-small cell lung cancer: a non-randomized phase II study. ( Aerts, JG; Gras, J; Hoogsteden, H; Pouw, E; Pronk, T; Salomé, J; Schmitz, PI; Surmont, V; Tan, KY; van Klaveren, RJ; Vernhout, R, 2009) |
| " The most appropriate dosing option appeared to be 400 mg x m(-2) per day of oral UFT for 14 consecutive days with 900 mg x m(-2) gemcitabine on days 8 and 15." | 2.70 | A phase I study of combination chemotherapy with gemcitabine and oral UFT for advanced non-small cell lung cancer. ( Asoh, H; Ichinose, Y; Semba, H; Seto, T; Yamamoto, H; Yoh, K, 2002) |
| " Trials of new combinations are warranted to take advantage of the pharmacokinetic properties and oral bioavailability of UFT and leucovorin." | 2.68 | Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast. ( Belón, J; Blanco, E; Espinosa, E; Feliu, J; Garcia Alfonso, P; Garcia Girón, C; Garrido, P; González Barón, M; Jara, C; Ruiz, A; Vincent, JM; Zamora, P, 1997) |
| " Based on those results, we conducted a pilot study to confirm the feasibility and antitumor effect of UFT in combination with cisplatin in patients with advanced non-small cell lung cancer (NSCLC)." | 2.68 | Pilot study of UFT combined with 5 consecutive days cisplatin in non-small cell lung cancer. ( Koinumaru, S; Matsuda, T; Nakai, Y; Saitoh, J, 1997) |
| "Tegafur acts as a prodrug of 5-fluorouracil (5-FU), being slowly metabolized by cytochrome P450 to 5-FU." | 2.40 | UFT and leucovorin: a review of its clinical development and therapeutic potential in the oral treatment of cancer. ( Benner, SE; Canetta, R; Hoff, PM; Pazdur, R, 1998) |
| "Tegafur/uracil (UFT) is an oral fluorinated pyrimidine composed of a combination of uracil and tegafur in a 4:1 molar ratio." | 2.40 | The role of tegafur/uracil in pulmonary malignancy. ( Langer, CJ, 1999) |
| " We compared the antibody titers of SARS-CoV-2 vaccines and the adverse events between patients who received adjuvant UFT and patients who did not." | 1.91 | Comparable efficacy and safety of COVID-19 vaccines for patients receiving tegafur-uracil as postoperative adjuvant chemotherapy. ( Doi, T; Funakoshi, Y; Hojo, W; Hokka, D; Maniwa, Y; Minami, H; Mitsui, S; Nishikubo, M; Ohji, G; Sakai, H; Tanaka, Y; Yakushijin, K, 2023) |
| "The extent of lymphatic metastasis is the most important factor in the prognosis for non-small cell lung cancer (NSCLC)." | 1.31 | Suppression of mediastinal metastasis by uracil-tegafur or cis-diamminedichloroplatinum(II) using a lymphogenous metastatic model in a human lung cancer cell line. ( Fujino, H; Ishikura, H; Kinoshita, H; Kondo, K; Miyoshi, T; Monden, Y; Takahashi, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.23) | 18.7374 |
| 1990's | 21 (25.93) | 18.2507 |
| 2000's | 43 (53.09) | 29.6817 |
| 2010's | 11 (13.58) | 24.3611 |
| 2020's | 5 (6.17) | 2.80 |
| Authors | Studies |
|---|---|
| Li, XY | 1 |
| Zhang, TJ | 1 |
| Kamara, MO | 1 |
| Lu, GQ | 1 |
| Xu, HL | 1 |
| Wang, DP | 1 |
| Meng, FH | 1 |
| Yamaguchi, M | 2 |
| Tada, H | 3 |
| Mitsudomi, T | 1 |
| Seto, T | 4 |
| Yokoi, K | 1 |
| Katakami, N | 1 |
| Nakagawa, K | 2 |
| Oda, M | 2 |
| Ohta, M | 7 |
| Sawa, T | 1 |
| Yamashita, M | 3 |
| Iked, N | 1 |
| Saka, H | 1 |
| Higashiyama, M | 1 |
| Nomori, H | 1 |
| Semba, H | 6 |
| Negoro, S | 1 |
| Chiba, Y | 1 |
| Shimokawa, M | 1 |
| Fukuoka, M | 1 |
| Nakanishi, Y | 2 |
| Okamoto, K | 1 |
| Kaku, R | 1 |
| Oshio, Y | 1 |
| Hanaoka, J | 1 |
| Nishikubo, M | 1 |
| Tanaka, Y | 2 |
| Mitsui, S | 1 |
| Doi, T | 1 |
| Hokka, D | 1 |
| Hojo, W | 1 |
| Sakai, H | 1 |
| Funakoshi, Y | 1 |
| Yakushijin, K | 1 |
| Ohji, G | 1 |
| Minami, H | 1 |
| Maniwa, Y | 1 |
| Liang, SK | 1 |
| Wu, CW | 1 |
| Chang, CI | 1 |
| Keng, LT | 1 |
| Lee, MR | 1 |
| Wang, JY | 1 |
| Ko, JC | 1 |
| Liao, WY | 1 |
| Chen, KY | 1 |
| Ho, CC | 1 |
| Shih, JY | 1 |
| Yu, CJ | 1 |
| Tsuchiya, T | 2 |
| Kamohara, R | 2 |
| Muraoka, M | 2 |
| Nagayasu, T | 1 |
| Saeki, S | 1 |
| Takenoyama, M | 1 |
| Suzuki, M | 1 |
| Inada, K | 1 |
| Tokunaga, S | 1 |
| Hayashi, T | 1 |
| Urabe, S | 2 |
| Koga, T | 2 |
| Akamine, S | 2 |
| Sugio, K | 1 |
| Sawada, S | 1 |
| Sugimoto, R | 1 |
| Ueno, T | 1 |
| Rossi, A | 1 |
| Novello, S | 1 |
| Kashiwabara, K | 1 |
| Fujii, S | 1 |
| Tsumura, S | 1 |
| Soh, J | 1 |
| Toyooka, S | 2 |
| Okumura, N | 1 |
| Nakamura, H | 1 |
| Nakata, M | 1 |
| Sakamoto, J | 1 |
| Aoe, M | 1 |
| Hotta, K | 1 |
| Morita, S | 1 |
| Date, H | 1 |
| Minomo, S | 1 |
| Asami, K | 1 |
| Okishio, K | 1 |
| Kawaguchi, T | 1 |
| Fujita, Y | 1 |
| Takata, S | 1 |
| Tamura, A | 1 |
| Saitou, R | 1 |
| Atagi, S | 1 |
| Hishida, T | 1 |
| Tsuboi, M | 3 |
| Shukuya, T | 1 |
| Takamochi, K | 1 |
| Sakurai, H | 1 |
| Yoh, K | 2 |
| Ohashi, Y | 1 |
| Kunitoh, H | 1 |
| Koyama, T | 1 |
| Funato, Y | 1 |
| Yamaguchi, Y | 1 |
| Ito, K | 1 |
| Yamanaka, T | 1 |
| Nakano, M | 1 |
| Ota, M | 1 |
| Maruyama, R | 2 |
| Okamoto, T | 4 |
| Wataya, H | 1 |
| Uematsu, K | 1 |
| Seki, N | 1 |
| Eguchi, K | 1 |
| Ichinose, Y | 14 |
| Nishimura, N | 1 |
| Sugiura, R | 1 |
| Ueda, H | 2 |
| Ono, H | 1 |
| Horinouchi, H | 1 |
| Uchiyama, N | 1 |
| Chohnabayashi, N | 1 |
| Surmont, V | 1 |
| Aerts, JG | 1 |
| Pouw, E | 1 |
| Tan, KY | 1 |
| Vernhout, R | 1 |
| Gras, J | 1 |
| Salomé, J | 1 |
| Pronk, T | 1 |
| Schmitz, PI | 1 |
| Hoogsteden, H | 1 |
| van Klaveren, RJ | 1 |
| Hamada, C | 1 |
| Fujimura, S | 2 |
| Kodama, K | 2 |
| Imaizumi, M | 1 |
| Wada, H | 16 |
| Suehisa, H | 1 |
| Tanaka, F | 13 |
| Fukushima, M | 4 |
| Baek, JH | 2 |
| Kim, H | 2 |
| Ahn, JJ | 2 |
| Jegal, Y | 2 |
| Seo, KW | 2 |
| Ra, SW | 1 |
| Park, CR | 2 |
| Jung, JP | 2 |
| Kim, JW | 2 |
| Lee, YJ | 1 |
| Cha, HJ | 2 |
| Kwon, WJ | 2 |
| Noh, YJ | 2 |
| Oh, S | 1 |
| Park, JH | 2 |
| Min, YJ | 2 |
| Kuwata, T | 1 |
| Iwata, T | 1 |
| Iwanami, T | 1 |
| Kawaguchi, M | 1 |
| Nakagawa, T | 2 |
| Takata, T | 1 |
| Matsuoka, K | 1 |
| Miyahara, R | 6 |
| Otake, Y | 4 |
| Yanagihara, K | 4 |
| Fukushimab, M | 1 |
| Teruya, T | 1 |
| Ikeda, J | 2 |
| Ushijima, C | 3 |
| Asoh, H | 6 |
| Fukuyama, Y | 2 |
| Hanaoka, N | 1 |
| Hattori, K | 1 |
| Kohchi, Y | 1 |
| Oikawa, N | 1 |
| Suda, H | 1 |
| Ura, M | 1 |
| Ishikawa, T | 1 |
| Miwa, M | 1 |
| Endoh, M | 1 |
| Eda, H | 1 |
| Tanimura, H | 1 |
| Kawashima, A | 1 |
| Horii, I | 1 |
| Ishitsuka, H | 1 |
| Shimma, N | 1 |
| Endo, C | 1 |
| Saito, Y | 1 |
| Iwanami, H | 1 |
| Tsushima, T | 2 |
| Imai, T | 1 |
| Kawamura, M | 1 |
| Kondo, T | 1 |
| Koike, K | 1 |
| Handa, M | 1 |
| Kanno, R | 1 |
| Yano, T | 5 |
| Nomiyama, H | 1 |
| Hidaka, H | 1 |
| Okamoto, J | 1 |
| Sakai, M | 1 |
| Sakada, T | 1 |
| Kuwahara, M | 1 |
| Motohiro, A | 2 |
| Kato, H | 1 |
| Hata, E | 1 |
| Tsubota, N | 2 |
| Watanabe, Y | 1 |
| Hamajima, N | 1 |
| Diasio, RB | 1 |
| Nakai, Y | 2 |
| Kudoh, S | 4 |
| Yoshida, S | 1 |
| Nukiwa, T | 1 |
| Yamamoto, H | 3 |
| Yamane, Y | 1 |
| Niitani, H | 3 |
| Nakagawa, M | 1 |
| Takao, M | 1 |
| Ishikawa, S | 2 |
| Wilhelm, L | 1 |
| Kolesar, JM | 1 |
| Itoh, K | 1 |
| Inoue, Y | 1 |
| Araki, J | 1 |
| Tamanoi, M | 1 |
| Iwamoto, N | 1 |
| Stewart, L | 1 |
| Burdett, S | 1 |
| Pisters, KM | 1 |
| Solomon, B | 1 |
| Mitchell, JD | 1 |
| Bunn, PA | 1 |
| Park, I | 1 |
| Chung, KY | 1 |
| Kim, KD | 1 |
| Kim, DJ | 1 |
| Nakano, J | 1 |
| Huang, C | 1 |
| Liu, D | 1 |
| Masuya, D | 1 |
| Nakashima, T | 1 |
| Yokomise, H | 1 |
| Ueno, M | 1 |
| Akashi, A | 1 |
| Yasumitsu, T | 1 |
| Iuchi, K | 1 |
| Taki, T | 1 |
| Hanada, M | 1 |
| Noguchi, T | 1 |
| Yamaoka, T | 1 |
| Tsuji, K | 1 |
| Honda, S | 1 |
| Yamasaki, N | 1 |
| Hanibuchi, M | 1 |
| Yano, S | 1 |
| Tomimoto, H | 1 |
| Sone, S | 2 |
| Chou, KT | 1 |
| Chen, YM | 1 |
| Shih, JF | 1 |
| Perng, RP | 1 |
| Tsai, CM | 1 |
| Whang-Peng, J | 1 |
| Ono, Y | 1 |
| Hino, M | 1 |
| Ueda, Y | 1 |
| Kamizuru, R | 1 |
| Omata, M | 1 |
| Uehara, T | 2 |
| Soma, T | 1 |
| Kanaji, N | 1 |
| Bandoh, S | 1 |
| Ishida, T | 1 |
| Shin, SJ | 1 |
| Shin, JK | 1 |
| Jeong, AK | 1 |
| Takayama, K | 1 |
| Kawasaki, M | 1 |
| Ninomiya, K | 1 |
| Fujita, M | 1 |
| Watanabe, K | 1 |
| Kajiki, A | 1 |
| Iwami, F | 1 |
| Miyazaki, N | 1 |
| Izumi, M | 1 |
| Hara, N | 3 |
| Takanashi, N | 2 |
| Yokoyama, H | 3 |
| Tayama, K | 2 |
| Kinoshita, T | 1 |
| Akaogi, E | 1 |
| Mitsui, K | 1 |
| Onizuka, M | 1 |
| Morita, R | 1 |
| Ishibashi, O | 1 |
| Suga, M | 1 |
| Inagaki, M | 1 |
| Okazaki, H | 1 |
| Uchida, J | 1 |
| Satake, H | 1 |
| Saito, H | 1 |
| Nakano, K | 1 |
| Takeda, S | 1 |
| Unemi, N | 1 |
| Miura, T | 1 |
| Matsuoka, Y | 1 |
| Feld, R | 1 |
| Hitomi, S | 5 |
| Teramatsu, T | 1 |
| Ito, H | 1 |
| Fukuda, Y | 1 |
| Maruyama, A | 1 |
| Fujita, H | 1 |
| Yagihashi, N | 1 |
| Tsuge, T | 1 |
| Ishioka, T | 1 |
| Kudo, T | 1 |
| Kishibe, S | 1 |
| Sato, T | 1 |
| Machida, S | 1 |
| Kogawa, R | 1 |
| Takashima, K | 1 |
| Koie, H | 1 |
| Fujita, K | 1 |
| Kobayashi, K | 1 |
| Feliu, J | 1 |
| González Barón, M | 1 |
| Zamora, P | 1 |
| Garcia Alfonso, P | 1 |
| Garcia Girón, C | 1 |
| Blanco, E | 1 |
| Belón, J | 1 |
| Garrido, P | 1 |
| Jara, C | 1 |
| Ruiz, A | 1 |
| Vincent, JM | 1 |
| Espinosa, E | 1 |
| Yoshimori, K | 1 |
| Morikawa, T | 1 |
| Kuba, M | 2 |
| Koinumaru, S | 1 |
| Matsuda, T | 1 |
| Saitoh, J | 1 |
| Taguchi, T | 1 |
| Seike, M | 1 |
| Andoh, M | 1 |
| Hasegawa, K | 1 |
| Sakonji, M | 1 |
| Tsuboi, E | 1 |
| Ohtake, Y | 1 |
| Fukuse, T | 1 |
| Hoff, PM | 1 |
| Pazdur, R | 1 |
| Benner, SE | 1 |
| Canetta, R | 1 |
| Kanematsu, T | 1 |
| Yohena, T | 1 |
| Wada, S | 1 |
| Yosimori, K | 1 |
| Yoneda, S | 1 |
| Langer, CJ | 2 |
| Yamada, T | 1 |
| Kawano, Y | 1 |
| Li, M | 1 |
| Inui, K | 1 |
| Ishikura, H | 1 |
| Kondo, K | 1 |
| Miyoshi, T | 1 |
| Kinoshita, H | 1 |
| Takahashi, Y | 1 |
| Fujino, H | 1 |
| Monden, Y | 1 |
| Shimizu, E | 1 |
| Kimura, K | 1 |
| Inoue, I | 1 |
| Nakamura, Y | 1 |
| Noda, Y | 1 |
| Hojo, F | 1 |
| Yagi, M | 1 |
| Nakanishi, S | 1 |
| Yamasaki, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Chemotherapy Versus Observation in Fully Resected Stage I Lung Adenocarcinoma With High Risk of Post-operative Recurrence[NCT03380468] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2018-01-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for uracil and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Effect of postoperative adjuvant chemotherapy with tegafur-uracil on survival in patients with stage IA non-small cell lung cancer: an exploratory analysis from a meta-analysis of six randomized controlled trials.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung | 2009 |
Adjuvant chemotherapy for completely resected non-small-cell lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Clinical Trials as To | 2009 |
UFT and S-1 for treatment of primary lung cancer.
Topics: Administration, Oral; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; | 2010 |
Angiogenesis and the efficacy of postoperative administration of UFT in pathologic stage I non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, | 2004 |
[Postoperative adjuvant chemotherapy for non-small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemoth | 2005 |
Adjuvant chemotherapy for non-small-cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lun | 2003 |
Adjuvant chemotherapy for resected non-small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 2005 |
[Efficacy of postoperative adjuvant therapy for resected non-small cell lung cancer--an evidence-based review].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Drug Combinations; Ev | 2006 |
[Adjuvant chemotherapy for non-small cell lung cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chem | 2006 |
[Clinical use of platinum compounds and fluorinated pyrimidines for lung cancer].
Topics: Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin | 1996 |
[Adjuvant chemotherapy for non-small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Combined | 1997 |
UFT: biochemical modulation for 5-fluorouracil (5-FU).
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as | 1997 |
UFT and leucovorin: a review of its clinical development and therapeutic potential in the oral treatment of cancer.
Topics: Administration, Oral; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Smal | 1998 |
The role of tegafur/uracil in pulmonary malignancy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical | 1999 |
The role of UFT and the combination of UFT/leucovorin in non-small cell lung cancer.
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcino | 2001 |
34 trials available for uracil and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Phase III study of adjuvant gemcitabine compared with adjuvant uracil-tegafur in patients with completely resected pathological stage IB-IIIA non-small cell lung cancer (WJTOG0101).
Topics: Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Deoxycytidine; Gemcitabine; Humans; Lung Neo | 2021 |
A single-arm, phase 2 study of adjuvant chemotherapy with oral tegafur-uracil for pathologically lymphovascular invasion positive stage IA non-small cell lung cancer: LOGIK0602 study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Vessels; Carcinoma, Non-Small-Cell Lung; | 2020 |
Impact of pathological stage and histological subtype on clinical outcome of adjuvant chemotherapy of paclitaxel plus carboplatin versus oral uracil-tegafur for non-small cell lung cancer: subanalysis of SLCG0401 trial.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2019 |
Phase II study of triplet chemotherapy using Tegafur-Uracil, Vinorelbine, Gemcitabine for advanced non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; | 2013 |
Tegafur-uracil plus gemcitabine combination chemotherapy in patients with advanced non-small cell lung cancer previously treated with platinum.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L | 2008 |
Oral UFT, etoposide and leucovorin in recurrent non-small cell lung cancer: a non-randomized phase II study.
Topics: Administration, Oral; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small | 2009 |
Prospective phase II trial of a combination of gemcitabine and UFT as first-line treatment in elderly patients with advanced non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L | 2012 |
A randomized trial of postoperative UFT therapy in p stage I, II non-small cell lung cancer: North-east Japan Study Group for Lung Cancer Surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up St | 2003 |
Induction chemoradiotherapy and surgical resection for selected stage IIIB non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat | 2003 |
A small randomized phase III single-center trial on postoperative UFT administration in patients with completely resected non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Disease-Free S | 2004 |
A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2004 |
Uracil/tegafur plus cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer: a multi-institutional phase II trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; | 2004 |
A randomized phase III trial of adjuvant chemotherapy with UFT for completely resected pathological stage I non-small-cell lung cancer: the West Japan Study Group for Lung Cancer Surgery (WJSG)--the 4th study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinom | 2005 |
Role of adjuvant chemotherapy in the treatment of non-small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 2005 |
UFT plus gemcitabine combination chemotherapy in patients with advanced non-small-cell lung cancer: a multi-institutional phase II trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; | 2005 |
Adjuvant UFT therapy does not increase survival in people with resected stage 1 non-small cell lung cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, No | 2005 |
Randomised study of adjuvant chemotherapy for completely resected p-stage I-IIIA non-small cell lung cancer.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemoth | 2006 |
Phase II randomized study of weekly docetaxel alone or plus UFUR treatment in non-small cell lung cancer patients who failed previous chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small | 2008 |
Phase I study of paclitaxel, carboplatin and UFT in chemo-naive patients with advanced non-small cell lung cancer (NSCLC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell | 2007 |
Prospective phase II trial of a combination of fixed dose rate infusion of gemcitabine with cisplatin and UFT as a first-line treatment in patients with advanced non-small-cell lung carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat | 2008 |
Phase II study of uracil-tegafur plus cisplatin in patients with previously untreated advanced non-small cell lung cancer.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell | 2008 |
A phase II trial of oral tegafur and uracil plus cisplatin in patients with inoperable nonsmall cell lung cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Sm | 1995 |
A randomized trial of postoperative adjuvant chemotherapy in non-small cell lung cancer (the second cooperative study). The Study Group of Adjuvant Chemotherapy for Lung Cancer (Chubu, Japan).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemoth | 1995 |
[Chemotherapy with oral etoposide, UFT and carboplatin in non-small cell lung cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc | 1994 |
Adjuvant chemotherapy after complete resection in non-small-cell lung cancer. West Japan Study Group for Lung Cancer Surgery.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineo | 1996 |
[A randomized controlled study of post-operative adjuvant therapy in non-small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemoth | 1996 |
Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carci | 1997 |
Postoperative adjuvant chemotherapy for non-small-cell lung cancer. West Japan Study Group for Lung Cancer Surgery. The Japan Lung Cancer Research Group on Postsurgical Adjuvant Chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Combinations; Humans; Japan; Lung Neopla | 1997 |
UFT plus cisplatin in advanced non-small-cell lung cancer: interim analysis of 67 patients.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cispla | 1997 |
Pilot study of UFT combined with 5 consecutive days cisplatin in non-small cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cel | 1997 |
Postoperative adjuvant chemotherapy with PVM (Cisplatin + Vindesine + Mitomycin C) and UFT (Uracil + Tegaful) in resected stage I-II NSCLC (non-small cell lung cancer): a randomized clinical trial. West Japan Study Group for lung cancer surgery (WJSG).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 1999 |
UFT plus cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat | 1999 |
UFT plus cisplatin combination chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma: a multiinstitutional phase II trial. For the Japan UFT Lung Cancer Study Group.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carci | 2000 |
A phase I study of combination chemotherapy with gemcitabine and oral UFT for advanced non-small cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cel | 2002 |
32 other studies available for uracil and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Mo | 2019 |
Impact of thoracic esophageal displacement after lobectomy on the continuity of oral adjuvant chemotherapy.
Topics: Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chem | 2022 |
Comparable efficacy and safety of COVID-19 vaccines for patients receiving tegafur-uracil as postoperative adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 2023 |
Oral uracil-tegafur compared with intravenous chemotherapy as adjuvant therapy for resected early-stage non-small cell lung cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 2023 |
Feasibility Trial of Oral UFT after Platinum-based Adjuvant Chemotherapy in Patients with Resected Non-small Cell Lung Cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2017 |
The Tradition of the Rising Sun: When Geography Counts.
Topics: Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Geography; Humans; Lung Neoplas | 2018 |
Toxicity and Efficacy of Sequential Chemotherapy in Patients with p-stage I Non-small Cell Lung Cancer that Recurring during Postoperative Tegafur-Uracil Adjuvant Chemotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L | 2018 |
Multicenter observational cohort study of post-operative treatment for completely resected non-small-cell lung cancer of pathological Stage I (T1 >2 cm and T2 in TNM classification version 6).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuva | 2015 |
[Results of a Special Drug Use-Results Survey on Compliance to Tegafur/Uracil(UFT)Adjuvant Chemotherapy for Non-Small Cell Lung Cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L | 2015 |
Gemcitabine plus UFT combination chemotherapy as second- or third-line therapy in non-small cell lung cancer: a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycy | 2008 |
Surgical resection of a metastatic skull tumor from lung cancer.
Topics: Adenocarcinoma, Papillary; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Smal | 2012 |
Predictive value of dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (Tegafur + Uracil) in patients with p-stage I nonsmall-cell lung cancer.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Dihydrouraci | 2002 |
[A case of preoperative concurrent chemoradiotherapy and curative resection for locally advanced non-small-cell lung cancer].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisp | 2002 |
Prognostic significance of p53 status in non-small cell lung cancer in correlation with postoperative adjuvant therapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Smal | 2002 |
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcino | 2003 |
[UFT plus cisplatin with concurrent radiotherapy in unresectable stage III non-small cell lung cancer--its application to outpatient practice].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cel | 2003 |
Adjuvant chemotherapy for adenocarcinoma of the lung--is the standard of care ready for change?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chem | 2004 |
UFT inhibits lung metastases in spontaneous metastasis model of lung cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Drug Combinat | 2005 |
Prognostic factors for disease-free survival in pT2N0 non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemoth | 2006 |
Evaluations of biomarkers associated with 5-FU sensitivity for non-small-cell lung cancer patients postoperatively treated with UFT.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Non-Small | 2006 |
Amrubicin, a novel 9-aminoanthracycline, enhances the antitumor activity of chemotherapeutic agents against human cancer cells in vitro and in vivo.
Topics: Animals; Anthracyclines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, | 2007 |
Stage IA non-small cell lung cancer: vessel invasion is a poor prognostic factor and a new target of adjuvant chemotherapy.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; | 2007 |
[Differences in the therapeutic strategies for lung cancer between Europe/United States and Japan].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carc | 2007 |
Dramatic response to uracil-tegafur (UFT) in an elderly patient with nonsmall cell lung cancer.
Topics: Administration, Oral; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell | 2007 |
[Experimental evaluation of combination chemotherapy with UFT and cisplatin for lung cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; | 1994 |
[Chemotherapy with cisplatin and daily administration of UFT for unresectable non-small cell lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, | 1993 |
Chemotherapy as adjuvant therapy for completely resected non-small-cell lung cancer: have we made progress?
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Smal | 1996 |
[Combination chemotherapy with continuous infusion of low-dose cisplatin and UFT for advanced non-small cell lung cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell L | 1998 |
Advantage of post-operative oral administration of UFT (tegafur and uracil) for completely resected p-stage I-IIIa non-small cell lung cancer (NSCLC).
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, | 1998 |
Apoptosis and p53 status predict the efficacy of postoperative administration of UFT in non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Divi | 2001 |
Suppression of mediastinal metastasis by uracil-tegafur or cis-diamminedichloroplatinum(II) using a lymphogenous metastatic model in a human lung cancer cell line.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cisplatin; Humans; Lung Ne | 2001 |
[A phase II study of UFT in non-small cell lung cancer].
Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small | 1986 |