Page last updated: 2024-10-20

uracil and Carcinoma, Lewis Lung

uracil has been researched along with Carcinoma, Lewis Lung in 7 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.

Research Excerpts

ExcerptRelevanceReference
" A number of UFT dosing protocols were evaluated such as short-term (daily, for 7 days) maximum tolerated dosing (MTD), e."1.34Contrasting effects of extended low dose versus standard dose shorter course UFT chemotherapy on microscopic versus macroscopic established tumors: implications for optimal postoperative adjuvant chemotherapy. ( Fujioka, A; Fukushima, M; Nakano, K; Oka, T; Okabe, H; Saito, H; Sugimoto, Y; Uchida, J, 2007)
"However, the sensitivity to the micrometastases was high."1.31Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model. ( Fujioka, A; Fukushima, M; Nakano, K; Okabe, H; Saito, H; Sato, K; Takechi, T; Takeda, S; Uchida, J; Unemi, N, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wei, J1
Blum, S1
Unger, M1
Jarmy, G1
Lamparter, M1
Geishauser, A1
Vlastos, GA1
Chan, G1
Fischer, KD1
Rattat, D1
Debatin, KM1
Hatzopoulos, AK1
Beltinger, C1
Miyahara, R1
Nakagawa, T1
Ishikawa, S1
Fukushima, M3
Wada, H1
Tanaka, F1
Uchida, J2
Okabe, H2
Nakano, K2
Fujioka, A2
Saito, H2
Sugimoto, Y1
Oka, T1
Katoh, R1
Ooshiro, M1
Hamada, A1
Fukushima, S1
Saneyoshi, M1
Shimizu, S1
Kawaguchi, T1
Nakano, M1
Nakanishi, H1
Kobayashi, K1
Nishimura, T1
Inada, K1
Tsukamoto, T1
Tatematsu, M1
Sato, K1
Takechi, T1
Takeda, S1
Unemi, N1

Other Studies

7 other studies available for uracil and Carcinoma, Lewis Lung

ArticleYear
Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.
    Cancer cell, 2004, Volume: 5, Issue:5

    Topics: Animals; Bone Neoplasms; Bystander Effect; Carcinoma, Lewis Lung; Cell Hypoxia; Cytosine Deaminase;

2004
UFT inhibits lung metastases in spontaneous metastasis model of lung cancer.
    The Thoracic and cardiovascular surgeon, 2005, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Drug Combinat

2005
Contrasting effects of extended low dose versus standard dose shorter course UFT chemotherapy on microscopic versus macroscopic established tumors: implications for optimal postoperative adjuvant chemotherapy.
    Oncology reports, 2007, Volume: 18, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung

2007
Enhancement of antitumor effect of tegafur/uracil (UFT) plus leucovorin by combined treatment with protein-bound polysaccharide, PSK, in mouse models.
    Cellular & molecular immunology, 2007, Volume: 4, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Colonic Neoplasms; Disease Models, Animal; Dr

2007
Acyclothymidine alleviates intestinal toxicity of 5'-deoxy-5-fluorouridine without loss of antitumor activity in mice.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Lewis Lung; Drug Syner

1996
Chemosensitivity of micrometastases and circulating tumor cells to uracil and tegafur as evaluated using LacZ gene-tagged Lewis lung carcinoma cell.
    Cancer letters, 1999, Jul-19, Volume: 142, Issue:1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Carcinoma, Lewis Lung; Cinnamates; H

1999
Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model.
    International journal of molecular medicine, 2000, Volume: 5, Issue:4

    Topics: Amputation, Surgical; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinom

2000