uracil has been researched along with Cancer of Prostate in 37 studies
2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder
Excerpt | Relevance | Reference |
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"To determine whether long-term oral administration of UFT, a combination of 5-fluorouracil and uracil, in addition to conventional estrogen therapy improved the response and survival of the patients with advanced stage D2 prostate adenocarcinoma, a randomized prospective study was performed with either estrogen alone (Honvan 200 mg/day or presexol 1 mg/day: group A) or estrogen plus UFT (400 mg/day:group B)." | 5.08 | [Combination therapy with estrogen and UFT in newly diagnosed prostatic cancer (poorly differentiated, stage D2)]. ( Fujii, H; Fukushima, S; Harada, M; Hosaka, M; Kondo, I; Kubota, Y; Miura, T, 1996) |
" UFT (a compound of tegafur and uracil) is said to be effective for bladder cancer." | 4.80 | [Progress in oral anti-cancer drug therapy for urological cancer]. ( Akaza, H; Tsukamoto, S, 1999) |
"This prospective and randomized clinical study was initiated to compare the efficacy and safety of combined androgen blockade with combination with UFT in patients with untreated prostate cancer." | 2.70 | Prospective and randomized comparison of combined androgen blockade versus combination with oral UFT as an initial treatment for prostate cancer. ( Kuriyama, M; Ohshima, S; Ono, Y; Sahashi, M; Shimizu, H; Takahashi, Y; Tanaka, T, 2001) |
"In the study of bladder cancer, neither a significant difference of non-recurrent rate nor of survival rate was seen between the two groups." | 2.69 | [Effect of UFT on treatment of urological cancer--effect of UFT on treatment of invasive bladder cancer and advanced prostate cancer. Ibaraki Urological Cancer Chemotherapy Study Group]. ( Akaza, H; Hattori, K; Ishikawa, S; Kawai, K; Kikuchi, K; Kobayashi, T; Koiso, K; Kondo, F; Manabe, F; Matsuki, K; Miyanaga, N; Noguchi, R; Shimazui, T; Suzuki, R; Takeshima, H; Tsuchiya, A; Uchida, K, 1998) |
"To evaluate the efficacy of chemoendocrine therapy for the initial treatment of stage D2 prostate cancer, we conducted a prospective randomized study which compared combined androgen blockade alone to that combined with UFT." | 2.69 | [Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT]. ( Akazawa, S; Aki, M; Hashine, K; Kuwahara, M; Sumiyoshi, Y; Takenaka, A; Yamamoto, A, 1999) |
"Of the 136 patients with prostate cancer enrolled in this study from April 1990 to December 1992, 69 received endocrine plus UFT therapy and the remaining 67 received endocrine-only therapy." | 2.69 | Endocrine plus uracil/tegafur therapy for prostate cancer. ( Kawada, Y; Kuriyama, M; Ohshima, S; Ono, Y; Shimizu, H; Takahashi, Y, 1999) |
"We evaluated the usefulness of hormonal therapy combined with UFT as initial treatment in comparison with hormonal therapy alone in 92 patients with Stage D2 prostatic cancer treated at the Department of Urology, Dokkyo University School of Medicine between 1974 and 1993." | 2.68 | [Clinical evaluation of chemohormonal therapy as an initial treatment for stage D2 prostatic cancer--effect of UFT administration combined with hormonal therapy]. ( Chen, JA; Honda, M; Hosoya, Y; Imai, T; Maeda, S; Suzuki, T; Takasaki, E, 1995) |
"Although prostate cancer initially responds well to endocrine therapy, it becomes resistant to the therapy a few years later, and is called hormone-refractory cancer." | 1.31 | [Long-term survival of hormone-refractory prostate cancer: a case report]. ( Fujimoto, N; Harada, S; Hida, T; Matsumoto, T, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (16.22) | 18.7374 |
1990's | 16 (43.24) | 18.2507 |
2000's | 9 (24.32) | 29.6817 |
2010's | 5 (13.51) | 24.3611 |
2020's | 1 (2.70) | 2.80 |
Authors | Studies |
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Spisz, P | 1 |
Kozak, W | 1 |
Chomicz-Mańka, L | 1 |
Makurat, S | 1 |
Falkiewicz, K | 1 |
Sikorski, A | 1 |
Czaja, A | 1 |
Rak, J | 1 |
Zdrowowicz, M | 1 |
Pulukuri, SM | 1 |
Knost, JA | 1 |
Estes, N | 1 |
Rao, JS | 1 |
Kawaguchi, T | 1 |
Mayama, I | 1 |
Iwabuchi, I | 1 |
Ogasawara, M | 1 |
Tsukui, A | 1 |
Hatano, K | 1 |
Nonomura, N | 3 |
Nishimura, K | 4 |
Kawashima, A | 1 |
Mukai, M | 1 |
Nagahara, A | 1 |
Nakai, Y | 2 |
Nakayama, M | 1 |
Takayama, H | 1 |
Tsujimura, A | 1 |
Okuyama, A | 3 |
Shimasaki, T | 1 |
Miyazawa, K | 1 |
Moriyama, M | 1 |
Tanaka, T | 2 |
Sato, I | 1 |
Nakaya, N | 1 |
Nakajima, H | 1 |
Kubo, A | 1 |
Suzuki, K | 1 |
Motoo, Y | 1 |
Kume, H | 1 |
Gamagedara, S | 1 |
Kaczmarek, AT | 1 |
Jiang, Y | 1 |
Cheng, X | 2 |
Rupasinghe, M | 1 |
Ma, Y | 1 |
Hoshi, S | 2 |
Ohyama, C | 2 |
Namiki, S | 1 |
Hagisawa, S | 2 |
Satoh, M | 2 |
Saito, S | 2 |
Ono, K | 2 |
Shirasaka, T | 1 |
Arai, Y | 4 |
Shimizu, K | 1 |
Tokizane, T | 1 |
Inoue, H | 1 |
Takaha, N | 2 |
Kamoi, K | 1 |
Ukimura, O | 1 |
Miki, T | 2 |
Koide, T | 1 |
Ichikawa, Y | 1 |
Sugao, H | 2 |
Yamaguchi, S | 1 |
Takatera, H | 1 |
Uchida, K | 4 |
Miura, H | 1 |
Fukuzaki, A | 1 |
Schinazi, RF | 1 |
Hurwitz, SJ | 1 |
Liberman, I | 1 |
Glazkova, Y | 1 |
Mourier, NS | 1 |
Olson, J | 1 |
Keane, T | 1 |
Bhandari, MS | 1 |
Pienta, KJ | 1 |
Fardig, J | 1 |
Olson, K | 1 |
Smith, DC | 1 |
Masuda, F | 1 |
Tashiro, K | 1 |
Machida, T | 1 |
Shida, K | 1 |
Yamanaka, H | 2 |
Ito, Y | 2 |
Shimazaki, J | 1 |
Isaka, S | 1 |
Yokokawa, M | 1 |
Fukui, I | 1 |
Kawai, H | 1 |
Akimoto, M | 1 |
Yoshida, K | 1 |
Maekawa, T | 1 |
Kashihara, N | 1 |
Tsujita, M | 1 |
Morikawa, Y | 1 |
Hayahara, N | 1 |
Nishijima, T | 1 |
Ezaki, K | 1 |
Senju, M | 1 |
Iritani, M | 1 |
Yamaguchi, M | 1 |
Honda, M | 1 |
Takasaki, E | 1 |
Suzuki, T | 1 |
Maeda, S | 2 |
Imai, T | 1 |
Hosoya, Y | 1 |
Chen, JA | 1 |
Hayashi, T | 2 |
Shiga, T | 1 |
Hattori, K | 2 |
Nishijima, Y | 2 |
Kasaya, S | 1 |
Shimazui, T | 2 |
Akaza, H | 4 |
Koiso, K | 3 |
Nemoto, R | 2 |
Sakai, H | 1 |
Minami, Y | 1 |
Kanetake, H | 1 |
Saito, Y | 1 |
Fujita, K | 4 |
Matsushima, H | 1 |
Nakano, M | 1 |
Kaneko, T | 1 |
Kasaya, T | 1 |
Harada, M | 2 |
Kondo, I | 1 |
Miura, T | 1 |
Fujii, H | 1 |
Fukushima, S | 1 |
Kubota, Y | 1 |
Hosaka, M | 1 |
Satake, H | 1 |
Fujioka, A | 1 |
Uchida, J | 1 |
Takeda, S | 1 |
Unemi, N | 1 |
Yee, LK | 1 |
Chu, E | 1 |
Pan, BC | 1 |
Chu, SH | 1 |
Chen, TM | 1 |
Lipsky, MH | 1 |
Chu, MY | 1 |
Calabresi, P | 1 |
Takeshima, H | 1 |
Kikuchi, K | 1 |
Miyanaga, N | 1 |
Kawai, K | 1 |
Tsuchiya, A | 1 |
Noguchi, R | 1 |
Manabe, F | 1 |
Matsuki, K | 1 |
Suzuki, R | 1 |
Ishikawa, S | 1 |
Kondo, F | 1 |
Kobayashi, T | 1 |
Tsukamoto, S | 1 |
Sumiyoshi, Y | 1 |
Hashine, K | 1 |
Kuwahara, M | 1 |
Aki, M | 1 |
Yamamoto, A | 1 |
Akazawa, S | 1 |
Takenaka, A | 1 |
Ono, Y | 3 |
Ohshima, S | 2 |
Takahashi, Y | 3 |
Kuriyama, M | 3 |
Kawada, Y | 2 |
Shimizu, H | 2 |
Nozawa, M | 1 |
Fukui, T | 1 |
Harada, Y | 1 |
Imazu, T | 1 |
Sahashi, M | 1 |
Fujimoto, N | 1 |
Harada, S | 1 |
Hida, T | 1 |
Matsumoto, T | 1 |
Munakata, A | 1 |
Shinoda, I | 1 |
Takeuchi, T | 1 |
Ban, Y | 1 |
Yamamoto, N | 1 |
Tada, K | 1 |
Imai, K | 1 |
Mashimo, T | 1 |
Yuasa, H | 1 |
Yoshida, M | 1 |
Asano, M | 1 |
Fukuzaki, H | 1 |
KumaKura, M | 1 |
Sakamoto, S | 1 |
Kusuyama, H | 1 |
Numa, H | 1 |
Okada, K | 1 |
Kagawa, S | 1 |
Takigawa, H | 1 |
Aga, Y | 1 |
Kurokawa, K | 1 |
Naito, K | 1 |
Hisazumi, H | 1 |
Misaki, T | 1 |
Shimada, K | 1 |
Miyazaki, K | 1 |
Kosaka, S | 1 |
Miyagi, T | 1 |
Murayama, T | 1 |
Sayama, T | 1 |
Abe, S | 1 |
2 reviews available for uracil and Cancer of Prostate
Article | Year |
---|---|
[Hormonal chemotherapy for hormone-refractory prostate cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto | 2002 |
[Progress in oral anti-cancer drug therapy for urological cancer].
Topics: Administration, Oral; Androgen Antagonists; Antineoplastic Agents, Hormonal; Drug Administration Sch | 1999 |
12 trials available for uracil and Cancer of Prostate
Article | Year |
---|---|
[Hormonal chemotherapy for hormone-refractory prostate cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Proto | 2002 |
Phase II trial of oral uracil/tegafur plus leucovorin in patients with hormone-refractory prostate carcinoma.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot | 2006 |
[Endocrine chemotherapy for prostatic cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlormadinone Acetate; Follow-Up Studies; Humans; Ma | 1994 |
[Clinical evaluation of chemohormonal therapy as an initial treatment for stage D2 prostatic cancer--effect of UFT administration combined with hormonal therapy].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Mo | 1995 |
Chemo-endocrine therapy for prostate cancer with bone metastasis. Nagasaki Prostate Cancer Research Group.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone | 1994 |
[Combination therapy with estrogen and UFT in newly diagnosed prostatic cancer (poorly differentiated, stage D2)].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Diethylstil | 1996 |
[Effect of UFT on treatment of urological cancer--effect of UFT on treatment of invasive bladder cancer and advanced prostate cancer. Ibaraki Urological Cancer Chemotherapy Study Group].
Topics: Administration, Oral; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents; Antineop | 1998 |
[Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antimetabolites, Antineoplastic; Anti | 1999 |
Endocrine plus uracil/tegafur therapy for prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 1999 |
Oral combination of cyclophosphamide, uracil plus tegafur and estramustine for hormone-refractory prostate cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Androgen Antagonists; Antimetabolites, Antineoplastic | 2001 |
Prospective and randomized comparison of combined androgen blockade versus combination with oral UFT as an initial treatment for prostate cancer.
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Pr | 2001 |
Fundamental study on the implantable LH-RH agonist/polymer and its use in a randomized trial for prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Implants; Drug Screening Assays, Antit | 1990 |
24 other studies available for uracil and Cancer of Prostate
Article | Year |
---|---|
5-(
Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Crystallography, X-Ray; Dermis; DNA; Fibrobla | 2020 |
Small interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stress.
Topics: Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; DNA Damage; Doxorubicin; Gene Ex | 2009 |
[Chemo-endocrine therapy with low-dose cisplatin, UFT, and dexamethasone for hormone-refractory prostate cancer patients].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; G | 2010 |
Retrospective analysis of an oral combination of dexamethasone, uracil plus tegafur and cyclophosphamide for hormone-refractory prostate cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combi | 2011 |
[Combination chemotherapy of docetaxel and UFT against hormone refractory prostate cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doce | 2011 |
[Oral antineoplastic agents for prostate cancer].
Topics: Administration, Oral; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combine | 2011 |
Validation study of urinary metabolites as potential biomarkers for prostate cancer detection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Chromatography, | 2012 |
[Low-dose cisplatin and UFT for hormone refractory prostate cancer].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Com | 2002 |
Complete regression of bone metastases on super bone scan, by low-dose cisplatin, UFT, diethylstilbestrol diphosphate, and dexamethasone in a patient with hormone-refractory prostate cancer.
Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bio | 2003 |
Tissue disposition of 5-o-carboranyluracil--a novel agent for the boron neutron capture therapy of prostate cancer.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Humans; Male; Mice; Mice, Nude; Organ Speci | 2004 |
[Clinical effect of UFT on urogenital tumors].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone an | 1984 |
[Phase II study of UFT for malignant tumors of urinary organs].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Comb | 1984 |
[Treatment of prostatic carcinoma with UFT and leucovorin--basic study using SRCA].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Humans; Leucovorin; Male; Mice; Mice, Inbre | 1994 |
[Ifosfamide in combined hormonochemotherapy on prostate cancer].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone | 1994 |
[Subrenal capsule assay of nude mice for testing the effectiveness of UFT for rat prostatic carcinoma (R3327)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cisplatin; Male; Mice; Mice, I | 1993 |
[Inhibition of prostate cancer growth in nude mice by hormone and chemotherapy].
Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Diethylsti | 1996 |
Benzylacyclouridine enhances 5-fluorouracil cytotoxicity against human prostate cancer cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Inter | 1998 |
[Long-term survival of hormone-refractory prostate cancer: a case report].
Topics: Adenocarcinoma; Administration, Oral; Aged; Androgen Antagonists; Chlormadinone Acetate; Combined Mo | 2001 |
[Experience of oral hormone-chemotherapy in prostatic cancer].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclo | 1991 |
[Studies on 5-FU concentration in serum and prostate cancer tissue after oral administration of UFT].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Male; Pr | 1991 |
[Lung metastases of prostatic cancer vanished by early combined hormonal and chemotherapy: report of a case].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality T | 1989 |
[Experimental study of UFT in prostatic carcinoma (DU-145) in nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line; Cells, Cultured; Hu | 1986 |
[Clinical effect of UFT on prostatic cancer].
Topics: Adenocarcinoma; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Hum | 1985 |
[A trial of hormonochemotherapy of prostate cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diethylstilbestrol; Humans; | 1985 |