Page last updated: 2024-10-20

uracil and Cancer of Head

uracil has been researched along with Cancer of Head in 51 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
"Patients with stage III, IVA, or IVB LAHNSCC were enrolled in this study to evaluate the efficacy of S-1 compared with UFT as adjuvant chemotherapy after curative CRT in the ACTS-HNC study."2.87Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study. ( Beppu, T; Fujii, M; Hanamure, Y; Hasegawa, Y; Higaki, Y; Iwae, S; Kawabata, K; Kohno, N; Kubota, A; Nagahara, K; Nakatani, E; Nakatani, H; Taguchi, T; Takemura, H; Terada, T; Teramukai, S; Tomita, K; Tsukahara, K; Yoshino, K, 2018)
"Irinotecan was supplied at doses of 40, 50, 60, and 70 mg/m(2) by using a standard 3+3 design."2.82Cisplatin/Tegafur/Uracil/Irinotecan Triple Combination Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: A Phase I/II Clinical Study. ( Chang, PM; Chen, SC; Yang, MH, 2016)
"Deleterious oral mucositis (OM) develops during radiotherapy (RT) or chemoradiotherapy for head-and-neck cancer (HNC) patients."2.77Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer. ( Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH, 2012)
"To test the efficacy and safety of pharmacokinetic modulating chemotherapy combined with cisplatin (PMC-cisplatin) as induction chemotherapy (ICT) before definitive treatment in patients with respectable locally advanced head and neck squamous cell carcinoma (HNSCC)."2.73Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study. ( Chang, PM; Chang, SY; Chen, PM; Chu, PY; Huang, JL; Tai, SK; Tsai, TL; Wang, LW; Wang, YF; Yang, MH, 2008)
" In total, 79 courses were administered with a median of 3 (range 1-6)."2.72UFT in combination with oxaliplatin: clinical phase I study in patients with advanced or metastatic solid tumors. ( Abad, A; Aranda, E; Carrato, A; Díaz-Rubio, E; Gallego, J; Gómez, A; López, E; Manzano, JL; Sastre, J, 2006)
"A trend of better distant control in head and neck cancer patients with post-operative adjuvant oral chemotherapy was observed."2.70Prospective randomized study of post-operative chemotherapy with levamisole and UFT for head and neck carcinoma. ( Ho, CM; Ho, WK; Lam, P; Wei, WI; Yuen, AP, 2001)
"Eniluracil is a novel DPD-inactivator designed to prolong the half-life of 5-FU and provide sustained plasma concentrations of 5-FU with oral dosing."2.69Phase I study of eniluracil, a dihydropyrimidine dehydrogenase inactivator, and oral 5-fluorouracil with radiation therapy in patients with recurrent or advanced head and neck cancer. ( Brockstein, B; Dolan, ME; Haraf, DJ; Humerickhouse, RA; Kies, M; Ratain, MJ; Stenson, K; Sulzen, L; Vokes, EE, 1999)
"For locally unresectable recurrent squamous cell carcinoma of the head and neck, we investigated two salvage chemotherapy regimens as second-line chemotherapy."2.69Prognosis after salvage chemotherapy for locally unresectable recurrent squamous cell carcinoma of the head and neck. ( Kawaida, M; Kitahara, S; Kohno, N; Ohmuma, T, 1999)
" Trials of new combinations are warranted to take advantage of the pharmacokinetic properties and oral bioavailability of UFT and leucovorin."2.68Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast. ( Belón, J; Blanco, E; Espinosa, E; Feliu, J; Garcia Alfonso, P; Garcia Girón, C; Garrido, P; González Barón, M; Jara, C; Ruiz, A; Vincent, JM; Zamora, P, 1997)
" The administration of the conventional dose of S-1 including dihydropyrimidine dehydrogenase (DPD), an metabolic inhibitor of 5-FU, results in exceeding the critical plasma concentration of 5-FU, and the long-term administration with high plasma concentration of 5-FU is considered to show clinical effectiveness in head and neck cancer."2.43[Clinical efficacy of administration with S-1 alone for head and neck carcinoma]. ( Horiuchi, C; Ishitoya, J; Katori, H; Matsuda, H; Mikami, Y; Taguchi, T; Toth, G; Tsukuda, M; Yoshida, T, 2006)
"Comparative clinical studies of head and neck cancer have not provided good evidence, with the exception of an RCT of adjuvant chemotherapy with UFT, in the past."2.41[Comparative clinical studies for head and neck cancer in Japan]. ( Fujii, M, 2002)
"The common clinical presentations of head and neck cancer include early (stage I or II) disease, locally or regionally advanced (stage III or IV, M0) disease, and recurrent or metastatic disease (< 5% of patients)."2.40Oral 5-FU alternatives for the treatment of head and neck cancer. ( Brockstein, BE; Haraf, DJ; Humerickhouse, R; Vokes, EE, 1998)
"5-Fluorouracil (5-FU) is a mainstay for treating various solid tumours in adults, including digestive and head and neck cancers."1.375-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases. ( Ciccolini, J; Cordier, PY; Lacarelle, B; Mercier, C; Nau, A; Oliver, M; Peytel, E, 2011)
"Thirty-one patients with head and neck cancer were administered pretreatment induction chemotherapy (so-called neo-adjuvant chemotherapy) consisting of a UFT and ADM combination."1.27[Neo-adjuvant chemotherapy with UFT and adriamycin in head and neck cancer]. ( Hyo, N; Imura, S; Kishimoto, M; Kumoi, T; Ogasawara, H; Toda, K, 1987)
"A Phase II study of UFT for head and neck cancer was conducted in 10 institutions."1.27[Phase II study of UFT for head and neck cancer]. ( Fujii, M; Hirokawa, T; Horiuchi, M; Inuyama, Y; Kaneko, S; Miyake, H; Ooyama, W; Takeda, C; Tanaka, J; Uchida, M, 1985)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19908 (15.69)18.7374
1990's21 (41.18)18.2507
2000's17 (33.33)29.6817
2010's5 (9.80)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishio-Nagai, M1
Suzuki, S1
Yoshikawa, K1
Ueda, R1
Kazaoka, Y1
Kubota, A3
Nakatani, E1
Tsukahara, K1
Hasegawa, Y1
Takemura, H1
Terada, T1
Taguchi, T4
Nagahara, K1
Nakatani, H1
Yoshino, K1
Higaki, Y1
Iwae, S1
Beppu, T1
Hanamure, Y1
Tomita, K1
Kohno, N4
Kawabata, K1
Teramukai, S1
Fujii, M8
Chen, SC1
Chang, PM2
Yang, MH2
Rivera, F3
Eugenia Vega-Villegas, M1
López, C1
Francisca López-Brea, M1
Rubio, A3
Del Valle, A3
García-Reija, F2
García-Montesinos, B2
Rodríguez-Iglesias, J2
Hinojo, C1
Márquez, R1
Angel Alonso-Bermejo, M1
Salcedo, M1
Blanco, Y1
Vega, N1
López-Tarruella, S1
Sanz-Ortiz, J3
Cordier, PY1
Nau, A1
Ciccolini, J1
Oliver, M1
Mercier, C1
Lacarelle, B1
Peytel, E1
Yen, SH1
Wang, LW2
Lin, YH1
Jen, YM1
Chung, YL1
Emura, T1
Nakagawa, F1
Fujioka, A1
Ohshimo, H1
Kitazato, K1
Furukawa, M1
Kawano, T1
Komatsu, M1
Sastre, J1
Aranda, E1
Abad, A1
Gallego, J1
Manzano, JL1
Gómez, A1
Carrato, A1
López, E1
Díaz-Rubio, E2
Tsukuda, M6
Ishitoya, J1
Mikami, Y1
Matsuda, H1
Katori, H2
Horiuchi, C1
Yoshida, T1
Toth, G1
Vega-Villegas, ME2
López-Brea, MF1
García-Castaño, A1
de Juan, A1
Ramos, FJ1
Collado, A1
Galdós, P2
Rama, J2
Mayorga, M2
López-Brea, M1
Isla, D1
Mayordomo, J1
Saiz-Bustillo, R1
Chen, PM1
Chu, PY1
Tai, SK1
Tsai, TL1
Huang, JL1
Wang, YF1
Chang, SY1
Kusama, M1
Utsunomiya, Y1
Ono, T1
Nagura, H1
Enomoto, S1
Ogasawara, H3
Kaneko, S3
Komiyama, S2
Horiuchi, M4
Inuyama, Y6
Uemura, T1
Uchida, M2
Kamata, S1
Okuda, M1
Homma, A1
Iizuka, K1
Nakamaru, Y1
Yonekawa, H1
Suzuki, K1
Itaya, S1
Tsuge, I1
Matsuda, T1
Motai, H1
Kobayashi, T1
Shimada, J1
Baba, S1
Fleming, RA2
Milano, GA1
Gaspard, MH1
Bargnoux, PJ1
Thyss, A2
Plagne, R1
Renée, N2
Schneider, M2
Demard, F2
Somekawa, Y1
Asano, K1
Taira, A1
Imai, R1
Fukuda, S2
Tanaka, K1
Kawaura, M1
Kawasaki, K1
Ohno, Y1
Tokumaru, Y1
Imanishi, Y1
Kanke, M1
Feliu, J1
González Barón, M1
Zamora, P1
Garcia Alfonso, P1
Garcia Girón, C1
Blanco, E1
Belón, J1
Garrido, P1
Jara, C1
Ruiz, A1
Vincent, JM1
Espinosa, E1
Furuta, Y1
Yagi, K1
Nagahashi, T1
Chida, E1
Shirato, H2
Kanzaki, J1
Colevas, AD2
González-Larriba, JL1
Garcia Carbonero, I1
Sastre Valera, J1
Perez Segura, P1
Vokes, EE2
Brockstein, BE1
Humerickhouse, R1
Haraf, DJ2
Humerickhouse, RA1
Dolan, ME1
Brockstein, B1
Stenson, K1
Kies, M1
Sulzen, L1
Ratain, MJ1
Kawakami, M1
Ikai, S1
Hashimoto, K1
Ito, T1
Takenaka, H1
Nishino, H1
Abe, K1
Ishikawa, K1
Kanazawa, T1
Tanaka, H1
Miyata, M1
Kitamura, K1
Morita, M1
Kitahara, S1
Kawaida, M1
Ohmuma, T1
Nishimura, G1
Yanoma, S1
Mizuno, H1
Satake, K1
Ikeda, Y1
Mercke, C1
Lewis, NL1
Meropol, NJ1
Amrein, PC1
Gomolin, H1
Barton, JJ1
Read, RR1
Adak, S1
Benner, S1
Costello, R1
Posner, MR1
Knowling, M1
Browman, G1
Siu, L1
Khoo, K1
Cooke, A1
Tannock, I1
Klaassen, D1
Cripps, C1
Goss, G1
Matthews, S1
Clarke, R1
Seymour, L1
Lam, P1
Yuen, AP1
Ho, CM1
Ho, WK1
Wei, WI1
Katayama, A1
Nonaka, S1
Bandoh, N1
Imada, M1
Hayashi, T1
Harabuchi, Y1
Nakashima, T1
Miyagi, M1
Kusumoto, T1
Milano, G1
Etienne, MC1
Ohyama, M1
Matsumura, M1
Katsuta, K1
Nobori, T1
Matsuyama, H1
Fukami, K1
Kiyota, R1
Yano, H1
Shima, T1
Ogawa, K1
Sugita, M1
Miyake, H3
Takahashi, H1
Yao, K1
Sawaki, S1
Takeyama, I1
Kikuchihara, M1
Kubota, T1
Tsuji, H2
Tsujii, H2
Kamada, T2
Takamura, A2
Matsuoka, Y2
Irie, G2
Usubuchi, H1
Tanaka, J3
Takaoka, T2
Hosoda, H2
Tachibana, M1
Yasuda, N1
Yoshimatsu, M1
Nishimura, H1
Mizukoshi, O1
Toda, K1
Kishimoto, M1
Imura, S1
Hyo, N1
Kumoi, T1
Takeda, C1
Hirokawa, T1
Ooyama, W1
Saito, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase Ib/II Study of Ramucirumab (Cyramza®), Nal-IRI (ONIVYDE®) and Trifluridine/Tipiracil (Lonsurf®) in Second Line Metastatic Gastric Cancer (COOL Study).[NCT05927857]Phase 1/Phase 245 participants (Anticipated)Interventional2023-09-01Not yet recruiting
A Phase II Study of Maintenance Tegafur-uracil in Patients With Squamous Cell Carcinoma of Oral Cavity With Extracapsular Spreading of Lymph Nodes[NCT03121313]Phase 268 participants (Anticipated)Interventional2015-02-26Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for uracil and Cancer of Head

ArticleYear
[Comparative clinical studies for head and neck cancer in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:9

    Topics: Antineoplastic Agents; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials as Topic; Com

2002
[Clinical efficacy of administration with S-1 alone for head and neck carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33 Suppl 1

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

2006
[Head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci

1996
The role of chemotherapy in the treatment of head and neck cancer.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Chemotherapy,

1997
Future directions in the treatment of squamous cell carcinoma of the head and neck: the role of UFT.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Che

1997
Oral 5-FU alternatives for the treatment of head and neck cancer.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:10 Suppl 7

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol

1998
Oral fluoropyrimidines in cancer treatment.
    Cancer investigation, 2000, Volume: 18, Issue:8

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Colo

2000

Trials

22 trials available for uracil and Cancer of Head

ArticleYear
Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC study.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemor

2018
Cisplatin/Tegafur/Uracil/Irinotecan Triple Combination Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma: A Phase I/II Clinical Study.
    The oncologist, 2016, Volume: 21, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell;

2016
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; E

2012
UFT in combination with oxaliplatin: clinical phase I study in patients with advanced or metastatic solid tumors.
    Anti-cancer drugs, 2006, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials,

2006
Long term results of a phase II trial of induction chemotherapy with uracil-ftegafur (UFT), vinorelbine and cisplatin (UFTVP) followed by radiotherapy concomitant with UFT and carboplatin (RT/UFTJ) in non-resectable locally advanced (stage IV-B) squamous
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2007, Volume: 9, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Car

2007
Concurrent chemoradiotherapy with carboplatin and uracil-f tegafur (UFT) for patients with poor performance status with locally advanced squamous cell carcinoma of the head and neck (SCCHN).
    Acta oto-laryngologica, 2007, Volume: 127, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; F

2007
Randomized phase II study of cisplatin and 5-FU continuous infusion (PF) versus cisplatin, UFT and vinorelbine (UFTVP) as induction chemotherapy in locally advanced squamous cell head and neck cancer (LA-SCHNC).
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease-Free Su

2008
Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 63, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2008
[A prospective randomized trial of adjuvant chemotherapy with UFT for head and neck carcinoma. Head and Neck UFT Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo

1994
[Determination of 5-FU tissue concentrations after oral UFT administration in tumors of the head and neck].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamo

1996
[Combination chemotherapy with 5-FU and CDDP or CDDP analog for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:13

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squ

1996
Experience of Oncopaz Cooperative Group with oral fluoropyrimidines in tumors of the stomach, lung, head and neck, and breast.
    Oncology, 1997, Volume: 54 Suppl 1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carci

1997
Neoadjuvant therapy with cisplatin/fluorouracil vs cisplatin/UFT in locally advanced squamous cell head and neck cancer.
    Oncology (Williston Park, N.Y.), 1997, Volume: 11, Issue:9 Suppl 10

    Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous C

1997
Phase I study of eniluracil, a dihydropyrimidine dehydrogenase inactivator, and oral 5-fluorouracil with radiation therapy in patients with recurrent or advanced head and neck cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combin

1999
[Combined chemotherapy with low-dose cisplatin, tegafur and uracil for head and neck squamous cell carcinomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carci

1999
Prognosis after salvage chemotherapy for locally unresectable recurrent squamous cell carcinoma of the head and neck.
    Japanese journal of clinical oncology, 1999, Volume: 29, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dr

1999
UFT/leucovorin in advanced squamous cell carcinoma of the head and neck administered with radiotherapy.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:10 Suppl 9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda

2000
A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck.
    Cancer, 2001, Jul-15, Volume: 92, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Antimetabolites, Antineoplastic; Antin

2001
A National Cancer Institute of Canada clinical trials group phase II study of eniluracil (776C85) and oral 5-fluorouracil in patients with advanced squamous cell head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Canada

2001
Prospective randomized study of post-operative chemotherapy with levamisole and UFT for head and neck carcinoma.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2001, Volume: 27, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; He

2001
[Investigation of UFT and radiation combination therapy of head and neck cancer--mainly in laryngeal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

1990
Clinical trials on UFT in the treatment of head and neck cancer.
    Auris, nasus, larynx, 1985, Volume: 12 Suppl 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Clinical Tria

1985

Other Studies

22 other studies available for uracil and Cancer of Head

ArticleYear
Adoptive immunotherapy combined with FP treatment for head and neck cancer: An in vitro study.
    International journal of oncology, 2017, Volume: 51, Issue:5

    Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Prolifera

2017
Retrospective analysis of surgical resection after induction chemotherapy for patients with T4b squamous cell head and neck cancer.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell;

2008
5-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Brain; Dihydropyrimidine Dehydrogenase Deficiency; Electroenc

2011
Thymidine kinase and thymidine phosphorylase level as the main predictive parameter for sensitivity to TAS-102 in a mouse model.
    Oncology reports, 2004, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Drug Combinations; Head and Neck Neoplasms; Humans; M

2004
[Nedaplatin for recurrent cancer of the head and neck].
    Nihon Jibiinkoka Gakkai kaiho, 2004, Volume: 107, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2004
[Level of 5-FU in tumor tissues of the patients with head and neck malignant tumors after oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Fluorourac

1983
[The effect of induction chemotherapy with CBDCA, 5-FU and UFT in head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:5

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug Admini

1994
[Tissue and serum levels of 5-FU in the patients with head and neck malignant tumors--influence of a streptococcal preparation OK-432].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Head and Neck Neo

1993
Dihydropyrimidine dehydrogenase activity in cancer patients.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Head and N

1993
[Giant metastatic neck tumor responding to oral administration of UFT--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:6

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule;

1999
Therapeutic effect of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypridine-1 M potassium oxonate (S-1) on head and neck squamous carcinoma cells.
    Cancer letters, 2000, Oct-16, Volume: 159, Issue:1

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy

2000
[Evaluation of preoperative simultaneous radiochemotherapy combined with carboplatin and tegafur.uracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carbop

2002
[Chemosensitivity of head and neck squamous cell carcinomas using subrenal capsule assay--comparative assay of 5-FU, FT, UFT, and HCFU and immunohistochemical study].
    Nihon Jibiinkoka Gakkai kaiho, 1992, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

1992
Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients.
    Cancer research, 1992, May-15, Volume: 52, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Head and N

1992
[A comparative study of UFT enteric-coated granules with UFT capsules on the occurrence of side effects in patients with head and neck cancers--a special attention to the upper gastrointestinal tract disorders].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capsules; Diarrhea;

1990
[Usage of urine FT levels for medication compliance in head and neck cancer with administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Fluorouracil;

1990
[Combined chemotherapy and radiotherapy in recurrent tumors of the head and neck region].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphami

1987
Improved results in the treatment of nasopharyngeal carcinoma using combined radiotherapy and chemotherapy.
    Cancer, 1989, May-01, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma,

1989
[Preoperative chemotherapy for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Ne

1985
UFT for head and neck cancers: its tissue concentrations and effects on lymphocyte subpopulations.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Combined Modali

1987
[Neo-adjuvant chemotherapy with UFT and adriamycin in head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda

1987
[Phase II study of UFT for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Head and Neck

1985