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uracil and Cancer of Cervix

uracil has been researched along with Cancer of Cervix in 26 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
" 5-Fluorouracil (5-FU) was effective against only one bladder cancer xenograft among 6 cancer xenografts tested."3.68[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice]. ( Adachi, S; Akaza, H; Ishitsuka, H; Kanazawa, K; Miwa, M; Nitta, K; Sekiguchi, F; Tokita, H, 1991)
"The stage IIB-IIIB cervical cancer patients were randomized to have Tegafur-Uracil 225 mg/m(2)/day orally, 5 days a week and carboplatin 100 mg/m(2) IV over 30-60 min, weekly on day 1 concurrent with standard radiotherapy (Group A) or carboplatin alone concurrent with standard radiotherapy (Group B)."2.73A randomized phase III trial of concurrent chemoradiotherapy in locally advanced cervical cancer: preliminary results. ( Kamnerdsupaphon, P; Khorprasert, C; Lertsanguansinchai, P; Lorvidhaya, V; Sangruchi, S; Sookpreedee, L; Suntornpong, N; Udompunturak, S; Veerasarn, V, 2007)
"Total 21 cases of cervical cancer were alloted randomly into 5'-DFUR group (daily dose 800 mg for 3 days) consisting of 11 patients and UFT group (daily dose 600 mg for 3 days) consisting of 10 patients, the unchanged substances (5'-DFUR in the 5'-DFUR group and tegafur concentrations in the UFT group) and 5-FU concentrations in serum and tissues were measured 6 hours after administration of the drugs."2.68[5-FU concentrations in the blood and tumor tissue after 5'-DFUR or UFT administration in the patients with uterine cervical cancer]. ( Aida, I; Kasuga, Y; Ohwada, M; Sato, I; Suzuki, M; Tamura, T, 1995)
"Complete cases among them consisted of ovarian cancer 53 cases, uterine cervical cancer 86 cases and endometrial cancer 27 cases for a total of 166 cases."2.67[Maintenance chemotherapy using UFT and FT for gynecological malignant tumors. The Gunma Prefectural Society for Study of Chemotherapy for Gynecological Cancer]. ( Ibuki, Y; Igarashi, M; Ito, T; Kimura, H; Kosuge, T; Nagayama, M; Nogami, Y; Ohwada, N; Tsukagoshi, T; Yazaki, K, 1992)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199013 (50.00)18.7374
1990's8 (30.77)18.2507
2000's4 (15.38)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sakaguchi, I1
Motohara, T1
Saito, F1
Takaishi, K1
Fukumatsu, Y1
Tohya, T1
Shibata, S2
Mimori, H1
Tashiro, H1
Katabuchi, H1
Hattori, K1
Kohchi, Y1
Oikawa, N1
Suda, H1
Ura, M1
Ishikawa, T1
Miwa, M2
Endoh, M1
Eda, H1
Tanimura, H1
Kawashima, A1
Horii, I1
Ishitsuka, H2
Shimma, N1
CAVANAGH, D1
MARTIN, DS1
FERGUSON, JH1
Veerasarn, V1
Lorvidhaya, V1
Kamnerdsupaphon, P1
Suntornpong, N1
Sangruchi, S1
Lertsanguansinchai, P1
Khorprasert, C1
Sookpreedee, L1
Udompunturak, S1
Nagai, N2
Mukai, K1
Hirata, E1
Jin, HH1
Komatsu, M1
Yunokawa, M1
Hatae, M1
Terahara, M1
Hokanishi, H1
Shimizu, A1
Watanabe, S1
Okuyama, D1
Morioka, M1
Yoda, A1
Hoshino, K1
Noguchi, Y1
Takahashi, J1
Notake, Y1
Mitsuya, T1
Suzuki, M3
Aida, I1
Ohwada, M2
Sato, I1
Tamura, T1
Kasuga, Y1
Kato, T1
Yakushiji, M1
Yamabe, T1
Sugimori, H1
Hidaki, T1
Tsukamoto, N1
Tazaki, T1
Foksinski, M1
Jaruga, P1
Makarewicz, R1
Olinski, R1
Oshita, T1
Shigemasa, K1
Ohama, K1
Takehara, K1
Miyaoka, S1
Shiota, M1
Shirai, T1
Tateyama, I1
Ohwada, N1
Nagayama, M1
Kosuge, T1
Tsukagoshi, T1
Ibuki, Y1
Igarashi, M1
Yazaki, K1
Ito, T1
Nogami, Y1
Kimura, H1
Sekiguchi, F1
Akaza, H1
Tokita, H1
Nitta, K1
Adachi, S1
Kanazawa, K1
Sekiguchi, I2
Tamada, T2
Yabushita, H1
Sawaguchi, K1
Ueno, N1
Hieda, S1
Noguchi, M1
Ishihara, M1
Yamashita, K1
Mitani, K1
Morishita, Y1
Inoue, K2
Tanimura, T1
Kaneshige, E2
Fujiwara, K1
Kobashi, Y1
Kono, I1
Sekiba, K2
Nagai, S1
Kamiya, H1
Sato, K1
Sakai, K1
Noda, K1
Teshima, K1
Ikeda, M1
Sugawa, T1
Yamagata, S1
Kohno, I1
Sawaragi, I1
Matsuoka, I1
Inoue, S1
Okumura, A1
Tanaka, T1
Onitsuka, Y1
Yoshimura, T1
Aiko, A1
Ikuta, Y1
Fukuma, K1
Matsuura, K1
Kawai, Y1
Hirano, H1
Taniguchi, H1
Nishiyama, M1
Yanase, H1
Uematsu, A1
Sugiyama, Y1
Kosoĭ, GKh1
Kholodnyi, MD1
Mindlin, SS1
Klunichenko, AM1

Trials

6 trials available for uracil and Cancer of Cervix

ArticleYear
High-dose oral tegafur-uracil maintenance therapy in patients with uterine cervical cancer.
    Journal of gynecologic oncology, 2015, Volume: 26, Issue:3

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Female;

2015
A randomized phase III trial of concurrent chemoradiotherapy in locally advanced cervical cancer: preliminary results.
    Gynecologic oncology, 2007, Volume: 104, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Female; Huma

2007
[5-FU concentrations in the blood and tumor tissue after 5'-DFUR or UFT administration in the patients with uterine cervical cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:2

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Fluoroura

1995
[A multicenter cooperative study on supplementary chemotherapy of uterocervical cancer. The Kyushu UFT Study Group of Uterocervical Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj

1994
[Maintenance chemotherapy using UFT and FT for gynecological malignant tumors. The Gunma Prefectural Society for Study of Chemotherapy for Gynecological Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Humans;

1992
[Phase II study of UFT in cancer of the uterine cervix].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cel

1985

Other Studies

20 other studies available for uracil and Cancer of Cervix

ArticleYear
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.
    Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcino

2003
CLOSED PELVIC PERFUSION IN ADVANCED GYNECOLOGIC CANCER.
    Southern medical journal, 1965, Volume: 58

    Topics: Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; F

1965
UFT and its metabolite gamma-butyrolactone (GBL) inhibit angiogenesis induced by vascular endothelial growth factor in advanced cervical carcinoma.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2

    Topics: 4-Butyrolactone; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocol

2008
[Comparative pharmacokinetic study between UFT and FT-207 suppo and phase II studies in gynecological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female

1984
[A case report: complete remission of stage IV uterine cervix carcinoma by immuno-chemotherapy with intraarterial infusion using implantable reservoir system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined

1995
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectro

1998
[A case of uterine cervical cancer in which UFT was an effective preoperative treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration

1999
[A patient with recurrent uterine cervical cancer successfully treated by combined modality therapy including local injection of anticancer agents based on CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doxorubic

2000
[Comparative studies on the antitumor activity of fluorinated pyrimidine derivatives against human bladder, cervical and ovarian cancer xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine;

1991
Thymidylate synthase inhibition as a predictor of tumor sensitivity of fluorinated pyrimidines.
    Asia-Oceania journal of obstetrics and gynaecology, 1990, Volume: 16, Issue:2

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Mice; Middle A

1990
[Experimental study on the effect of UFT with concomitant radiotherapy of uterine cervical cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Carcinoma, Squamous Cell

1989
[The concentration of 5-fluorouracil in blood and tissues of the patients with carcinoma of the cervix after administration of UFT and 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cel

1989
[5-FU, FT-207 and uracil concentrations in the serum and tissues of patients with cervical cancer after UFT oral administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:2

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sch

1986
[In vitro effects of 5-FU on gynecologic malignant tumor cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Cells, Cultured; Colony-Fo

1986
[UFT concentration in serum and tissues of patients with gynecologic malignant tumors following oral administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Endometrium; Female; Genital Neoplasms, Female; Huma

1985
[A study on plasma and tissue 5-FU concentrations in patients with cervical cancer treated with UFT].
    Nihon Gan Chiryo Gakkai shi, 1985, Apr-20, Volume: 20, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Humans; Tegafur; Uracil; Uteri

1985
[Level of 5-FU in uterine cervical cancer tissue after oral administration of UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cervix Ute

1985
[On the effect of methyluracil and Pentoxyl on induction of cancer of the uterine cervix and vagina in mice].
    Voprosy onkologii, 1968, Volume: 14, Issue:2

    Topics: Animals; Benz(a)Anthracenes; Colchicine; Female; Glycols; Mice; Neoplasms, Experimental; Thiotepa; U

1968
[The hypoplastic state of hematopoiesis following chemotherapy with alkylating compounds].
    Voprosy onkologii, 1969, Volume: 15, Issue:8

    Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Female; Hematologic Disease

1969
[The use of pentoxyl in radium therapy of malignant neoplasms of female genitalia].
    Akusherstvo i ginekologiia, 1966, Volume: 42, Issue:10

    Topics: Adult; Female; Humans; Middle Aged; Radium; Rectal Neoplasms; Uracil; Uterine Cervical Neoplasms; Ut

1966