Page last updated: 2024-10-20

uracil and Brain Neoplasms

uracil has been researched along with Brain Neoplasms in 18 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"A two-year-old boy with a malignant tumor of the brain (medulloblastoma) excreted large amounts of thymine and uracil in his urine."3.66Urinary excretion of thymine and uracil in a two-year-old child with a malignant tumor of the brain. ( Berglund, G; Greter, J; Lindstedt, S; Steen, G; Waldenström, J; Wass, U, 1979)
"He then underwent excision of the brain metastases and consecutive radiation by X-knife."1.32[A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy]. ( Arai, K; Iwasaki, Y; Katayanagi, S; Matsumoto, H; Miyamoto, H; Takahashi, K; Yamaguchi, T, 2003)
"He was diagnosed as having right renal cell carcinoma which had metastasized to the lung."1.28[A case of recurrence of a metastatic brain tumor which disappeared due to chemotherapy only]. ( Kayama, T; Ogawa, A; Sakurai, Y; Sato, K; Wada, T, 1990)
"Tamoxifen and UFT were administered as chemoendocrine therapy."1.28[A case of brain metastasis from breast cancer responding to chemoendocrine therapy]. ( Abe, R; Honda, K; Kanazawa, M; Nomizu, T; Tsuchiya, A; Watanabe, F; Yamaki, Y, 1990)
"Nineteen patients with brain tumors were orally administered 300 mg of UFT (a combination of FT and uracil with a molar ratio being 1:4) before operation and the concentrations of FT, 5-FU and Uracil in tumors and serum were measured by chemical assay."1.27[5-FU concentration in brain tumors after co-administration of FT and uracil]. ( Matsumoto, S; Nogaki, H; Tamaki, N; Taomoto, K, 1983)
"Thirteen patients with metastatic brain tumors were treated with two different chemotherapy regimens."1.27[The effect of combined chemotherapy with UFT, cis-platinum and aclarubicin in metastatic brain tumors]. ( Kida, Y; Kobayashi, T; Tanaka, T, 1987)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's4 (22.22)18.2507
2000's2 (11.11)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ignatowska, J1
Mironiuk-Puchalska, E1
Grześkowiak, P1
Wińska, P1
Wielechowska, M1
Bretner, M1
Karatsai, O1
Rędowicz, MJ1
Koszytkowska-Stawińska, M1
Tsukamoto, Y1
Ohtsu, N1
Echizenya, S1
Otsuguro, S1
Ogura, R1
Natsumeda, M1
Isogawa, M1
Aoki, H1
Ichikawa, S1
Sakaitani, M1
Matsuda, A1
Maenaka, K1
Fujii, Y1
Kondo, T1
Katayanagi, S1
Arai, K1
Iwasaki, Y1
Takahashi, K1
Yamaguchi, T1
Matsumoto, H1
Miyamoto, H1
Hatanaka, H1
Soloway, AH2
Sweet, H1
Harada, K2
Okamoto, H2
Kiya, K2
Fujioka, Y2
Uozumi, T2
Kodama, Y1
Nogaki, H1
Taomoto, K1
Tamaki, N1
Matsumoto, S1
Hirota, F1
Hosaka, K1
Funahashi, K1
Oota, M1
Ikeda, A1
Oobayashi, Y1
Fujii, S1
Inada, Y1
Murai, M1
Ishihama, H1
Berglund, G1
Greter, J1
Lindstedt, S1
Steen, G1
Waldenström, J1
Wass, U1
Sato, K1
Kayama, T1
Sakurai, Y1
Ogawa, A1
Wada, T1
Wakisaka, S2
Shimauchi, M2
Kaji, Y2
Nonaka, A2
Kinoshita, K2
Nomizu, T1
Watanabe, F1
Honda, K1
Kanazawa, M1
Yamaki, Y1
Tsuchiya, A1
Abe, R1
Kato, T1
Ota, K1
Tanaka, T1
Kobayashi, T1
Kida, Y1
Maruoka, N1
Moriyama, T1
Oyama, H1
Goya, T1
Kodama, T1
Coutelle, R1
Bonk, U1
Coutelle, C1
Felicetti, D1
Rath, FW1
Traub, F1
Butler, DN1

Other Studies

18 other studies available for uracil and Brain Neoplasms

ArticleYear
New insight into nucleo α-amino acids - Synthesis and SAR studies on cytotoxic activity of β-pyrimidine alanines.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Alanine; Antineoplastic Agents; beta-Alanine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:8

    Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell

2016
[A case of liver metastases from gastric cancer successfully treated with induced hypertensive chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Brain Neoplasm

2003
Incorporation of pyrimidines and boron analogues into brain tumour and brain tissue of mice. An approach to boron-neutron capture therapy.
    Neurochirurgia, 1967, Volume: 10, Issue:3

    Topics: Animals; Boron; Brain Neoplasms; Carbon Isotopes; DNA; Ependymoma; Mice; Neoplasms, Experimental; Ne

1967
[Pharmacokinetics study of UFT in malignant brain tumor patients].
    Neurologia medico-chirurgica, 1983, Volume: 23, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

1983
[5-FU concentration in brain tumors after co-administration of FT and uracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 1

    Topics: Brain Neoplasms; Drug Therapy, Combination; Fluorouracil; Glioblastoma; Humans; Meningeal Neoplasms;

1983
Pharmacodynamics of co-administration of uracil and 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) for malignant brain tumors.
    Hiroshima journal of medical sciences, 1983, Volume: 32, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neo

1983
[Effective treatment of AFP-producing lung cancer with UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; alpha-Fetoproteins; Antineoplastic Ag

1999
[A case of breast cancer with multiple metastases effectively treated with long-term administration of docetaxel, aclarubicin and UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:12

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Breast

2001
Urinary excretion of thymine and uracil in a two-year-old child with a malignant tumor of the brain.
    Clinical chemistry, 1979, Volume: 25, Issue:7

    Topics: Adolescent; Brain Neoplasms; Child, Preschool; Female; Fibroblasts; Humans; Leukemia, Lymphoid; Male

1979
[A case of recurrence of a metastatic brain tumor which disappeared due to chemotherapy only].
    No shinkei geka. Neurological surgery, 1990, Volume: 18, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Kidn

1990
Acute phenytoin intoxication associated with the antineoplastic agent UFT.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1990, Volume: 81, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; D

1990
[A case of brain metastasis from breast cancer responding to chemoendocrine therapy].
    Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:15

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma,

1990
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

1987
[The effect of combined chemotherapy with UFT, cis-platinum and aclarubicin in metastatic brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:9

    Topics: Aclarubicin; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neop

1987
[AUFRAP therapy: combined modality treatment of malignant gliomas with intraarterial infusion of ACNU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotid Artery, Internal; Co

1988
[Comparative histological and electron microscopic, histochemical and biochemical studies on invasive tumor growth. IV. Behavior of certain transferases oxidoreductases and hydrolases].
    Acta biologica et medica Germanica, 1970, Volume: 24, Issue:1

    Topics: Acid Phosphatase; Animals; Brain; Brain Chemistry; Brain Neoplasms; Carcinoma, Ehrlich Tumor; Glucur

1970
Attempted synthesis of 2,4-dihydroxy-43-borazaropyridine. Preparation of aminoalkylboronic acids.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:3

    Topics: Animals; Antimetabolites; Boron; Brain Neoplasms; Chemistry, Organic; Mice; Organic Chemistry Phenom

1966