Page last updated: 2024-10-20

uracil and Atherogenesis

uracil has been researched along with Atherogenesis in 8 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Research Excerpts

ExcerptRelevanceReference
" The current study investigated the effects of alogliptin, a DPP-4 inhibitor, on the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM)."9.22Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). ( Gosho, M; Jinnouchi, H; Kaneto, H; Katakami, N; Kosugi, K; Kuribayashi, N; Mita, T; Onuma, T; Osonoi, T; Shimomura, I; Shiraiwa, T; Umayahara, Y; Watada, H; Yamamoto, T; Yokoyama, H; Yoshii, H, 2016)
"The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) is a prospective, randomized, open-label, blinded-endpoint, multicenter, parallel-group, comparative study."9.17Rationale, design, and baseline characteristics of a trial for the prevention of diabetic atherosclerosis using a DPP-4 inhibitor: the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). ( Gosho, M; Jinnouchi, H; Kaneto, H; Katakami, N; Kosugi, K; Kuribayashi, N; Mita, T; Onuma, T; Osonoi, T; Shimomura, I; Shiraiwa, T; Umayahara, Y; Watada, H; Yamamoto, T; Yokoyama, H; Yoshii, H, 2013)
" The current study investigated the effects of alogliptin, a DPP-4 inhibitor, on the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM)."5.22Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). ( Gosho, M; Jinnouchi, H; Kaneto, H; Katakami, N; Kosugi, K; Kuribayashi, N; Mita, T; Onuma, T; Osonoi, T; Shimomura, I; Shiraiwa, T; Umayahara, Y; Watada, H; Yamamoto, T; Yokoyama, H; Yoshii, H, 2016)
"The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) is a prospective, randomized, open-label, blinded-endpoint, multicenter, parallel-group, comparative study."5.17Rationale, design, and baseline characteristics of a trial for the prevention of diabetic atherosclerosis using a DPP-4 inhibitor: the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). ( Gosho, M; Jinnouchi, H; Kaneto, H; Katakami, N; Kosugi, K; Kuribayashi, N; Mita, T; Onuma, T; Osonoi, T; Shimomura, I; Shiraiwa, T; Umayahara, Y; Watada, H; Yamamoto, T; Yokoyama, H; Yoshii, H, 2013)
"Treatment naïve subjects with type 2 diabetes received 12."2.80Alogliptin: a new dipeptidyl peptidase-4 inhibitor with potential anti-atherogenic properties. ( Hirate, M; Kaneoka, N; Kutoh, E, 2015)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katakami, N2
Mita, T2
Yoshii, H2
Onuma, T2
Kaneto, H2
Osonoi, T2
Shiraiwa, T2
Kosugi, K2
Umayahara, Y2
Yamamoto, T2
Yokoyama, H2
Kuribayashi, N2
Jinnouchi, H2
Gosho, M2
Watada, H2
Shimomura, I2
Kutoh, E1
Kaneoka, N1
Hirate, M1
Akita, K1
Isoda, K1
Shimada, K1
Daida, H1
Ta, NN1
Schuyler, CA1
Li, Y1
Lopes-Virella, MF1
Huang, Y1
Shah, Z1
Kampfrath, T1
Deiuliis, JA1
Zhong, J1
Pineda, C1
Ying, Z1
Xu, X1
Lu, B1
Moffatt-Bruce, S1
Durairaj, R1
Sun, Q1
Mihai, G1
Maiseyeu, A1
Rajagopalan, S1
FILLIOS, LC1
NAITO, C1
ANDRUS, SB1
ROACH, AM1
Takeshita, J1
Byun, J1
Nhan, TQ1
Pritchard, DK1
Pennathur, S1
Schwartz, SM1
Chait, A1
Heinecke, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Vildagliptin/Metformin Combination on Markers of Atherosclerosis, Thrombosis, and Inflammation in Diabetic Patients With Coronary Artery Disease[NCT01604213]Phase 460 participants (Actual)Interventional2012-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for uracil and Atherogenesis

ArticleYear
Rationale, design, and baseline characteristics of a trial for the prevention of diabetic atherosclerosis using a DPP-4 inhibitor: the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A).
    Journal of atherosclerosis and thrombosis, 2013, Volume: 20, Issue:12

    Topics: Aged; Atherosclerosis; Diabetes Complications; Dipeptidyl-Peptidase IV Inhibitors; Female; Humans; M

2013
Alogliptin: a new dipeptidyl peptidase-4 inhibitor with potential anti-atherogenic properties.
    Endocrine research, 2015, Volume: 40, Issue:2

    Topics: Adult; Aged; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipep

2015
Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A).
    Diabetes care, 2016, Volume: 39, Issue:1

    Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Medi

2016

Other Studies

5 other studies available for uracil and Atherogenesis

ArticleYear
Dipeptidyl-peptidase-4 inhibitor, alogliptin, attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein (LDL) receptor-deficient mice.
    Journal of the American Heart Association, 2015, Mar-13, Volume: 4, Issue:3

    Topics: Actins; Animals; Anti-Inflammatory Agents; Arteritis; Atherosclerosis; Biomarkers; Blood Glucose; Ce

2015
DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:2

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Cholesterol; Diabetes Mellitus, Experime

2011
Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis.
    Circulation, 2011, Nov-22, Volume: 124, Issue:21

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cell Movement; Chemotaxis; Dipeptidyl-P

2011
Further studies on experimental atherosclerosis and dietary pyrimidines: orotic acid, thiouracil, and uracil in male and female rats.
    Circulation research, 1960, Volume: 8

    Topics: Animals; Atherosclerosis; Diet; Female; Male; Orotic Acid; Pyrimidines; Rats; Thiouracil; Uracil

1960
Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages.
    The Journal of biological chemistry, 2006, Feb-10, Volume: 281, Issue:6

    Topics: Antioxidants; Aorta; Atherosclerosis; Chlorides; Chromatography, High Pressure Liquid; DNA; Dose-Res

2006