Page last updated: 2024-10-20

uracil and Asthenia

uracil has been researched along with Asthenia in 4 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Asthenia: Clinical sign or symptom manifested as debility, or lack or loss of strength and energy.

Research Excerpts

ExcerptRelevanceReference
"We investigated the efficacy and safety of oral Uracil/tegafur (UFT) with leucovorin and mitomycin C (MMC) as third-line treatment for patients with extensively pretreated metastatic colorectal cancer (mCRC)."9.16Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. ( Chamorey, E; Dahan, L; Evesque, L; Follana, P; Francois, E; Mari, V; Michel, C; Perrier, H; Seitz, JF; Smith, D, 2012)
"We investigated the efficacy and safety of oral Uracil/tegafur (UFT) with leucovorin and mitomycin C (MMC) as third-line treatment for patients with extensively pretreated metastatic colorectal cancer (mCRC)."5.16Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study. ( Chamorey, E; Dahan, L; Evesque, L; Follana, P; Francois, E; Mari, V; Michel, C; Perrier, H; Seitz, JF; Smith, D, 2012)
"The purpose of the current study was to determine the maximum tolerated dose, dose-limiting toxicities, pharmacokinetic profile, and recommended Phase II dose of oral administration of TAS-102, a novel nucleoside formed by the combination of alpha,alpha,alpha-trifluorothymidine (FTD) and a thymidine phosphorylase inhibitor (TPI: 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione)."2.72Phase I study to determine the safety and pharmacokinetics of oral administration of TAS-102 in patients with solid tumors. ( Abbruzzese, JL; Bogaard, K; Fukushima, M; Hoff, PM; Hong, DS; Kuwata, K; Lassere, Y; Mita, A, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Francois, E1
Smith, D1
Dahan, L1
Michel, C1
Perrier, H1
Mari, V1
Seitz, JF1
Follana, P1
Evesque, L1
Chamorey, E1
Hong, DS1
Abbruzzese, JL1
Bogaard, K1
Lassere, Y1
Fukushima, M1
Mita, A1
Kuwata, K1
Hoff, PM1
Daniels, M1
Díaz-Rubio, E1
Guillem, V1
Montero, JM1
García-Conde, J1
Estapé, J1
Martín, M1
Herranz, C1
Ordoñez, A1
Galán, A1
Lomazova, MM1

Trials

3 trials available for uracil and Asthenia

ArticleYear
Uracil-tegafur/leucovorin and mitomycin C salvage therapy in patients with advanced colorectal cancer: a phase II study.
    Journal of chemotherapy (Florence, Italy), 2012, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Antineoplastic Combined Chemotherap

2012
Phase I study to determine the safety and pharmacokinetics of oral administration of TAS-102 in patients with solid tumors.
    Cancer, 2006, Sep-15, Volume: 107, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Area Under Curve; Asthenia; Dose-Response

2006
Phase II trial of UFT activity in pretreated breast cancer patients.
    Japanese journal of clinical oncology, 1993, Volume: 23, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; A

1993

Other Studies

1 other study available for uracil and Asthenia

ArticleYear
[Treatment of ulcer disease and asthenic-depressive syndrome with methyluracil].
    Vrachebnoe delo, 1974, Volume: 0, Issue:9

    Topics: Adult; Asthenia; Depression; Duodenal Ulcer; Female; Humans; Syndrome; Uracil

1974