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uracil and Acquired Immunodeficiency Syndrome

uracil has been researched along with Acquired Immunodeficiency Syndrome in 5 studies

2,4-dihydroxypyrimidine: a urinary biomarker for bipolar disorder

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"AIDS Clinical Trials Group study A5334s evaluated the pharmacokinetics of raltegravir before and during combined administration of ombitasvir, paritaprevir/ritonavir, plus dasabuvir (OBV/PTV/r + DSV) and weight-based ribavirin in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfected adults."9.34Raltegravir pharmacokinetics before and during treatment with ombitasvir, paritaprevir/ritonavir plus dasabuvir in adults with human immunodeficiency virus-1 and hepatitis C virus coinfection: AIDS Clinical Trials Group sub-study A5334s. ( Alston-Smith, BL; Cohen, DE; Cramer, YS; Morse, GD; Rosenkranz, SL; Schmidt, J; Sulkowski, M; Venuto, CS; Wyles, DL, 2020)
"AIDS Clinical Trials Group study A5334s evaluated the pharmacokinetics of raltegravir before and during combined administration of ombitasvir, paritaprevir/ritonavir, plus dasabuvir (OBV/PTV/r + DSV) and weight-based ribavirin in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfected adults."5.34Raltegravir pharmacokinetics before and during treatment with ombitasvir, paritaprevir/ritonavir plus dasabuvir in adults with human immunodeficiency virus-1 and hepatitis C virus coinfection: AIDS Clinical Trials Group sub-study A5334s. ( Alston-Smith, BL; Cohen, DE; Cramer, YS; Morse, GD; Rosenkranz, SL; Schmidt, J; Sulkowski, M; Venuto, CS; Wyles, DL, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Venuto, CS2
Cramer, YS1
Rosenkranz, SL1
Sulkowski, M1
Wyles, DL2
Cohen, DE2
Schmidt, J1
Alston-Smith, BL1
Morse, GD2
Balagopal, A1
Smeaton, LM1
Quinn, J1
Vu, V1
Alston-Smith, B1
Santana-Bagur, JL1
Anthony, DD1
Sulkowski, MS1
Talal, AH1
Baba, M1
Shigeta, S1
Tanaka, H1
Miyasaka, T1
Ubasawa, M1
Umezu, K1
Walker, RT1
Pauwels, R1
De Clercq, E1
Araujo, FG1
Huskinson, J1
Remington, JS1
Falcone, A1
Darnowski, JW1
Ruprecht, RM1
Chu, SH1
Brunetti, I1
Calabresi, P1

Reviews

1 review available for uracil and Acquired Immunodeficiency Syndrome

ArticleYear
Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4-Positive T-Lymphocytes; Drug Combinations;

1992

Trials

2 trials available for uracil and Acquired Immunodeficiency Syndrome

ArticleYear
Raltegravir pharmacokinetics before and during treatment with ombitasvir, paritaprevir/ritonavir plus dasabuvir in adults with human immunodeficiency virus-1 and hepatitis C virus coinfection: AIDS Clinical Trials Group sub-study A5334s.
    British journal of clinical pharmacology, 2020, Volume: 86, Issue:1

    Topics: 2-Naphthylamine; Acquired Immunodeficiency Syndrome; Adult; Anilides; Antiviral Agents; Coinfection;

2020
Intrahepatic Viral Kinetics During Direct-Acting Antivirals for Hepatitis C in Human Immunodeficiency Virus Coinfection: The AIDS Clinical Trials Group A5335S Substudy.
    The Journal of infectious diseases, 2020, 07-23, Volume: 222, Issue:4

    Topics: 2-Naphthylamine; Acquired Immunodeficiency Syndrome; Adult; Anilides; Antiviral Agents; Carbamates;

2020

Other Studies

2 other studies available for uracil and Acquired Immunodeficiency Syndrome

ArticleYear
Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-Infective Agents; Atovaquone; Brain; Cell Division

1991
Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice.
    Blood, 1990, Dec-01, Volume: 76, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Dose-Response Relationship, Drug; Female; Kinet

1990