Page last updated: 2024-08-17

unithiol and Arsenic Encephalopathy

unithiol has been researched along with Arsenic Encephalopathy in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199013 (31.71)18.7374
1990's13 (31.71)18.2507
2000's8 (19.51)29.6817
2010's6 (14.63)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Gresham, C; Hsiao, CY; Marshall, MR1
Aaseth, J; Alexander, J; Bjørklund, G; Crisponi, G; Djordjevic, AB; Nurchi, VM1
Chen, CH; Chen, CK; Lu, PH; Tseng, JC1
Aaseth, J; Bjørklund, G; Mutter, J1
Kosnett, MJ1
Geng, Z; Hu, X; Li, X; Shi, N; Wang, S; Wang, Z1
Heitland, P; Köster, HD1
Ariño, C; Cavanillas, S; Chekmeneva, E; Díaz-Cruz, JM; Esteban, M1
Angerer, J; Heinrich-Ramm, R; Horn, J; Schaller, H1
LOBODA, IuI; LUHANS'KYI, MI1
Bhadauria, S; Dhaked, RK; Flora, SJ; Pant, SC1
Aposhian, HV; Aposhian, MM1
Flora, G; Flora, SJ; Mishra, M; Saxena, G1
Braber-Chernobul'skaia, BS; Chubenko, AV; Grigor'eva, AS; Luĭk, AI; Trinus, FP1
Aposhian, HV; Tadlock, CH1
Aposhian, HV3
Aposhian, HV; Brinkley, FB; Hackley, BE; Hsu, CA; Mershon, MM1
Aposhian, HV; Carter, DE; Hoover, TD; Hsu, CA; Maiorino, RM; Stine, E1
Maehashi, H; Tsutsumi, S; Yamaguchi, Y1
Aposhian, HV; Heydolph, S; Hsu, CA; Parr, W1
Fichtl, B; Forth, W; Kreppel, H; Mückter, H; Reichl, FX; Szinicz, L1
Doklea, E; Fichtl, B; Forth, W; Liebl, B; Mückter, H1
Arora, U; Dube, SN; Flora, SJ; Kannan, GM; Malhotra, PR; Shukla, MK1
Berlyne, G; Davies, HA; Henry, JA; House, IM; Moore, DF; O'Callaghan, CA; Ogg, CS1
Inns, RH; Rice, P1
Aihie, A; Brooks, D; Fysh, R; Jones, S; Kew, J; Morris, C1
Doklea, E; Fichtl, B; Forth, W; Hopfer, C; Islambouli, S; Mückter, H; Szinicz, L1
Fichtl, B; Forth, W; Hunder, G; Liebl, B; Reichl, FX1
Kołaciński, Z; Kruszewska, S; Mielczarska, J; Wiese, M1
Fichtl, B; Hunder, G; Liebl, B; Mückter, H; Reichl, FX; Walther, U1
Andrewes, P; Aposhian, HV; Aposhian, MM; Cebrian, ME; Cheng, Z; Cullen, W; Dart, RC; Healy, SM; Le, XC; Ma, M; Maiorino, RM; O'Malley, GF; Titcomb, A; Van Voorhies, W; Yip, L; Zakharyan, RA; Zheng, B1
Thornton, CA; Wax, PM1
Das, S; Das, T; De, BK; Ghosh, N; Guha Mazumder, DN; Lahiri, S; Santra, A1
Gol'dfarb, IuS; Molodkina, NN1
Balatskiĭ, KP1
Bohl, J; Goebel, HH; Gutmann, L; Krämer, G; Schmidt, PF; Tettenborn, B1
Bright, JE; Inns, RH; Marrs, TC; Rice, P1
Fichtl, B; Forth, W; Kreppel, H; Reichl, FX1
Miziukova, IG; Petrun'kin, VE1

Reviews

10 review(s) available for unithiol and Arsenic Encephalopathy

ArticleYear
Treatment of lead and arsenic poisoning in anuric patients - a case report and narrative review of the literature.
    BMC nephrology, 2019, 10-17, Volume: 20, Issue:1

    Topics: Adult; Animals; Anuria; Arsenic Poisoning; Chelating Agents; Continuous Renal Replacement Therapy; Dimercaprol; Edetic Acid; Humans; Kidney Failure, Chronic; Lead Poisoning; Male; Renal Dialysis; Succimer; Unithiol

2019
Arsenic Toxicity: Molecular Targets and Therapeutic Agents.
    Biomolecules, 2020, 02-04, Volume: 10, Issue:2

    Topics: Animals; Antidotes; Arsenic; Arsenic Poisoning; Arsenicals; Chelating Agents; Dimercaprol; Drinking Water; Humans; Models, Molecular; Occupational Exposure; Oxidative Stress; Succimer; Unithiol; Water Pollutants, Chemical

2020
Metal chelators and neurotoxicity: lead, mercury, and arsenic.
    Archives of toxicology, 2017, Volume: 91, Issue:12

    Topics: Arsenic Poisoning; Chelating Agents; Edetic Acid; Humans; Lead Poisoning, Nervous System; Mercury Poisoning, Nervous System; Monensin; Succimer; Unithiol

2017
The role of chelation in the treatment of arsenic and mercury poisoning.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013, Volume: 9, Issue:4

    Topics: Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Chelation Therapy; Humans; Mercury Poisoning; Succimer; Treatment Outcome; Unithiol

2013
Arsenic toxicology: five questions.
    Chemical research in toxicology, 2006, Volume: 19, Issue:1

    Topics: Animals; Arsenic; Arsenic Poisoning; Arsenites; Aryl Hydrocarbon Hydroxylases; Chelating Agents; Cytochrome P-450 CYP2C19; Dimercaprol; Enzyme Inhibitors; Glutathione Transferase; Hemoglobins; Humans; Metallothionein; Methylation; Mixed Function Oxygenases; Polymorphism, Genetic; Protein Binding; Pyruvate Dehydrogenase Complex; Reactive Oxygen Species; Succimer; Unithiol

2006
Arsenic and lead induced free radical generation and their reversibility following chelation.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Apr-15, Volume: 53, Issue:1

    Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Calcium; Chelating Agents; Free Radicals; Humans; Lead; Lead Poisoning; Melatonin; Metals; Micronutrients; Molecular Structure; Succimer; Taurine; Thioctic Acid; Unithiol; Vitamin E

2007
[Molecular mechanism of action of dithiols].
    Vestnik Akademii meditsinskikh nauk SSSR, 1984, Issue:11

    Topics: Animals; Antidotes; Arsenic Poisoning; Chelating Agents; Cholinesterase Inhibitors; Dimercaprol; Drug Interactions; Drug Stability; Drug Therapy, Combination; In Vitro Techniques; Kinetics; Metalloproteins; Metals; Neurotransmitter Agents; Protein Binding; Rabbits; Rats; Sulfhydryl Compounds; Sulfhydryl Reagents; Unithiol

1984
DMSA and DMPS--water soluble antidotes for heavy metal poisoning.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Animals; Antidotes; Arsenic Poisoning; Biotransformation; Cadmium Poisoning; Dimercaprol; Forecasting; Humans; Kinetics; Lead Poisoning; Mercury Poisoning; Metals; Solubility; Succimer; Sulfhydryl Compounds; Unithiol

1983
Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity.
    Annual review of pharmacology and toxicology, 1997, Volume: 37

    Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Biotransformation; Cricetinae; Guinea Pigs; Humans; Macaca mulatta; Methylation; Methyltransferases; Rabbits; Unithiol

1997
Are we ready to replace dimercaprol (BAL) as an arsenic antidote?
    Human & experimental toxicology, 1997, Volume: 16, Issue:8

    Topics: Animals; Antidotes; Arsenic Poisoning; Dimercaprol; Dogs; Guinea Pigs; Humans; Mice; Poisoning; Rats; Succimer; Unithiol

1997

Trials

1 trial(s) available for unithiol and Arsenic Encephalopathy

ArticleYear
Randomized placebo-controlled trial of 2,3-dimercapto-1-propanesulfonate (DMPS) in therapy of chronic arsenicosis due to drinking arsenic-contaminated water.
    Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:7

    Topics: Adult; Antidotes; Arsenic; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Chronic Disease; Drug Administration Schedule; Environmental Exposure; Female; Humans; Male; Prospective Studies; Single-Blind Method; Skin Diseases; Spectrophotometry, Atomic; Treatment Outcome; Unithiol; Water Pollutants, Chemical; Water Supply

2001

Other Studies

30 other study(ies) available for unithiol and Arsenic Encephalopathy

ArticleYear
Survival without peripheral neuropathy after massive acute arsenic poisoning: Treated by 2,3-dimercaptopropane-1-sulphonate.
    Journal of clinical pharmacy and therapeutics, 2017, Volume: 42, Issue:4

    Topics: Adult; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Chelating Agents; Female; Humans; Oxides; Peripheral Nervous System Diseases; Suicide, Attempted; Treatment Outcome; Unithiol

2017
Inhibitory mechanism of dimercaptopropanesulfonic acid (DMPS) in the cellular biomethylation of arsenic.
    Biochimie, 2014, Volume: 106

    Topics: Antidotes; Apoptosis; Arsenic; Arsenic Poisoning; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Gene Expression; Hep G2 Cells; Humans; Methylation; Methyltransferases; Organometallic Compounds; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Unithiol

2014
Comparison of different medical cases in urinary arsenic speciation by fast HPLC-ICP-MS.
    International journal of hygiene and environmental health, 2009, Volume: 212, Issue:4

    Topics: Adult; Aged; Arsenic Poisoning; Arsenicals; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Humans; Male; Middle Aged; Occupational Exposure; Suicide, Attempted; Unithiol; Young Adult

2009
Electroanalytical and isothermal calorimetric study of As(III) complexation by the metal poisoning remediators, 2,3-dimercapto-1-propanesulfonate and meso-2,3-dimercaptosuccinic acid.
    Analytica chimica acta, 2012, Oct-09, Volume: 746

    Topics: Arsenates; Arsenic Poisoning; Calorimetry; Chelating Agents; Electrochemical Techniques; Heavy Metal Poisoning; Humans; Least-Squares Analysis; Metals, Heavy; Normal Distribution; Poisoning; Spectrometry, Mass, Electrospray Ionization; Succimer; Unithiol

2012
Arsenic species excretion after dimercaptopropanesulfonic acid (DMPS) treatment of an acute arsenic trioxide poisoning.
    Archives of toxicology, 2003, Volume: 77, Issue:2

    Topics: Adult; Antidotes; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Humans; Male; Oxides; Suicide, Attempted; Time Factors; Treatment Outcome; Unithiol

2003
[Effect of unithiol and its analogues on SH groups in the blood serum of rabbits in conditions of arsenic poisoning].
    Ukrains'kyi biokhimichnyi zhurnal, 1961, Volume: 33

    Topics: Animals; Arsenic; Arsenic Poisoning; Inorganic Chemicals; Rabbits; Serum; Unithiol

1961
Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats.
    Life sciences, 2005, Sep-16, Volume: 77, Issue:18

    Topics: 5-Aminolevulinate Synthetase; Animals; Arsenic; Arsenic Poisoning; Chelating Agents; DNA Damage; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Male; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Unithiol

2005
Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid.
    Biochemical and biophysical research communications, 1980, May-30, Volume: 94, Issue:2

    Topics: Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Dimercaprol; Disease Models, Animal; Mice; Succimer; Sulfhydryl Compounds; Unithiol

1980
Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid.
    Advances in enzyme regulation, 1982, Volume: 20

    Topics: Animals; Arsenic Poisoning; Arsenites; Cadmium Poisoning; Chelating Agents; Dimercaprol; Lethal Dose 50; Male; Mice; Penicillamine; Sodium Compounds; Succimer; Sulfhydryl Compounds; Unithiol

1982
Anti-lewisite activity and stability of meso-dimercaptosuccinic acid and 2,3-dimercapto-1-propanesulfonic acid.
    Life sciences, 1982, Nov-08, Volume: 31, Issue:19

    Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenicals; Dimercaprol; Dose-Response Relationship, Drug; Drug Stability; Hydrogen-Ion Concentration; Injections, Subcutaneous; Male; Rabbits; Succimer; Unithiol

1982
DMSA, DMPS, and DMPA--as arsenic antidotes.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 2

    Topics: Animals; Antidotes; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Brain; Dimercaprol; Guinea Pigs; Male; Mice; Organ Size; Phthalic Acids; Pyruvate Dehydrogenase Complex; Rabbits; Sodium Compounds; Succimer; Sulfhydryl Compounds; Unithiol

1984
Arsenic and copper excretion after treatment of arsenic poisoning in rats with heavy-metal antagonists.
    Developments in toxicology and environmental science, 1983, Volume: 11

    Topics: Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Copper; Dimercaprol; Male; Rats; Rats, Inbred Strains; Succimer; Sulfhydryl Compounds; Unithiol

1983
Optical isomers of 2,3-dimercapto-1-propanesulfonate: antidotal activity, in vitro and in vivo, against sodium arsenite.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenites; Dimercaprol; Injections, Intraperitoneal; Isomerism; Male; Mice; Pyruvate Dehydrogenase Complex; Sodium Compounds; Unithiol

1983
Effect of various antidotes on the biliary and intestinal excretion of arsenic in situ and into the feces in vivo in guinea-pigs after injection of As2O3.
    Archives of toxicology, 1994, Volume: 69, Issue:1

    Topics: Animals; Antidotes; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Bile; Colon; Dimercaprol; Feces; Guinea Pigs; Injections, Intravenous; Jejunum; Male; Oxides; Perfusion; Poisoning; Succimer; Sulfonamides; Unithiol

1994
Reversal of oxophenylarsine-induced inhibition of glucose uptake in MDCK cells.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antidotes; Arsenic Poisoning; Arsenicals; Biological Transport; Cell Line; Dimercaprol; Dithiothreitol; Dogs; Enzyme Inhibitors; Glucose; L-Lactate Dehydrogenase; Mercaptoethanol; Succimer; Sulfonamides; Unithiol

1995
Therapeutic potential of meso 2,3-dimercaptosuccinic acid or 2,3-dimercaptopropane 1-sulfonate in chronic arsenic intoxication in rats.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 1995, Volume: 8, Issue:2

    Topics: Animals; Arsenic Poisoning; Chronic Disease; Kidney Tubules; Liver; Male; Poisoning; Rats; Succimer; Unithiol

1995
Acute arsenic poisoning: absence of polyneuropathy after treatment with 2,3-dimercaptopropanesulphonate (DMPS).
    Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:9

    Topics: Acute Disease; Adult; Arsenic Poisoning; Humans; Male; Peripheral Nervous System Diseases; Unithiol

1994
Efficacy of dimercapto chelating agents for the treatment of poisoning by percutaneously applied dichloro(2-chlorovinyl)arsine in rabbits.
    Human & experimental toxicology, 1993, Volume: 12, Issue:3

    Topics: Administration, Topical; Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Chemical and Drug Induced Liver Injury; Dimercaprol; Gallbladder; Lethal Dose 50; Liver; Lung; Male; Rabbits; Succimer; Sulfhydryl Compounds; Unithiol

1993
Arsenic and mercury intoxication due to Indian ethnic remedies.
    BMJ (Clinical research ed.), 1993, Feb-20, Volume: 306, Issue:6876

    Topics: Adult; Arsenic Poisoning; Humans; India; London; Male; Medicine, Traditional; Mercury Poisoning; Poisoning; Succimer; Unithiol

1993
Isolated rat kidney tubules as a screening system for arsenic antidotes.
    Toxicology and applied pharmacology, 1993, Volume: 121, Issue:1

    Topics: Animals; Antidotes; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Chelating Agents; Dimercaprol; Drug Evaluation, Preclinical; Gluconeogenesis; In Vitro Techniques; Kidney Tubules; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Succimer; Unithiol

1993
Effect of DMPS and various adsorbents on the arsenic excretion in guinea-pigs after injection with As2O3.
    Archives of toxicology, 1995, Volume: 69, Issue:10

    Topics: Animals; Anion Exchange Resins; Antidotes; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Bentonite; Charcoal; Cholestyramine Resin; Feces; Guinea Pigs; Injections, Subcutaneous; Male; Oxides; Unithiol

1995
The use of haemodialysis and 2,3 propanesulphonate (DMPS) to manage acute oral poisoning by lethal dose of arsenic trioxide.
    International journal of occupational medicine and environmental health, 1996, Volume: 9, Issue:2

    Topics: Adult; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Chelating Agents; Female; Humans; Oxides; Poisoning; Renal Dialysis; Toothpastes; Unithiol

1996
DMPS-arsenic challenge test. II. Modulation of arsenic species, including monomethylarsonous acid (MMA(III)), excreted in human urine.
    Toxicology and applied pharmacology, 2000, May-15, Volume: 165, Issue:1

    Topics: Adult; Animals; Arsenic Poisoning; Arsenicals; Cacodylic Acid; Chelating Agents; Female; Humans; Liver; Male; Methyltransferases; Middle Aged; Organometallic Compounds; Rabbits; Unithiol; Water Pollutants

2000
Recovery from severe arsenic-induced peripheral neuropathy with 2,3-dimercapto-1-propanesulphonic acid.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:7

    Topics: Adult; Arsenic; Arsenic Poisoning; Chelating Agents; Female; Humans; Peripheral Nervous System Diseases; Unithiol

2000
[Case of acute hydrogen arsenide poisoning].
    Gigiena truda i professional'nye zabolevaniia, 1978, Issue:7

    Topics: Accidents, Occupational; Acute Disease; Adult; Arsenic; Arsenic Poisoning; Diuresis; Environmental Exposure; Humans; Male; Moscow; Unithiol

1978
[Arsenic poisoning in animals].
    Veterinariia, 1976, Issue:9

    Topics: Acute Disease; Animals; Antidotes; Arsenic Poisoning; Cattle; Cattle Diseases; Dimercaprol; Drug Therapy, Combination; Male; Unithiol

1976
Polyneuropathy due to acute arsenic intoxication: biopsy studies.
    Journal of neuropathology and experimental neurology, 1990, Volume: 49, Issue:2

    Topics: Acute Disease; Adult; Arsenic Poisoning; Biopsy; Dimercaprol; Humans; Leg; Male; Microscopy, Electron; Muscles; Nerve Regeneration; Peripheral Nervous System Diseases; Sural Nerve; Unithiol

1990
Evaluation of the efficacy of dimercapto chelating agents for the treatment of systemic organic arsenic poisoning in rabbits.
    Human & experimental toxicology, 1990, Volume: 9, Issue:4

    Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Body Weight; Chelating Agents; Dimercaprol; Gallbladder; Lethal Dose 50; Liver; Lung; Male; Rats; Succimer; Unithiol

1990
Lack of effectiveness of D-penicillamine in experimental arsenic poisoning.
    Veterinary and human toxicology, 1989, Volume: 31, Issue:1

    Topics: Animals; Arsenic; Arsenic Poisoning; Dimercaprol; Guinea Pigs; Male; Mice; Penicillamine; Succimer; Tissue Distribution; Unithiol

1989
[Unithiol and mecaptid as antidotes in poisoning with arsenic-containing substances].
    Vrachebnoe delo, 1974, Issue:2

    Topics: Antidotes; Arsenic Poisoning; Dimercaprol; Drug Evaluation; Humans; Sulfhydryl Compounds; Unithiol

1974