uncialamycin has been researched along with Cystic-Fibrosis* in 1 studies
1 other study(ies) available for uncialamycin and Cystic-Fibrosis
Article | Year |
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Uncialamycin, a new enediyne antibiotic.
[structure: see text] Laboratory cultures of an undescribed streptomycete obtained from the surface of a British Columbia lichen produce uncialamycin (1), a new enediyne antibiotic. The structure of uncialamycin (1) has been elucidated by analysis of spectroscopic data. Uncialamycin (1) exhibits potent in vitro antibacterial activity against gram-positive and gram-negative human pathogens, including Burkholderia cepacia, a major cause of morbidity and mortality in patients with cystic fibrosis. Topics: Anthraquinones; Anti-Bacterial Agents; Bacteria; Burkholderia cepacia; Cystic Fibrosis; Humans; Molecular Structure; Streptomyces | 2005 |