ubiquinone and Muscle-Cramp

ubiquinone has been researched along with Muscle-Cramp* in 2 studies

Reviews

1 review(s) available for ubiquinone and Muscle-Cramp

ArticleYear
Exercise intolerance and the mitochondrial respiratory chain.
    Italian journal of neurological sciences, 1999, Volume: 20, Issue:6

    The syndrome of exercise intolerance, cramps, and myoglobinuria is a common presentation of metabolic myopathies and has been associated with several specific inborn errors of glycogen or lipid metabolism. As disorders in fuel utilization presumably impair muscle energy production, it was more than a little surprising that exercise intolerance and myoglobinuria had not been associated with defects in the mitochondrial respiratory chain, the terminal energy-yielding pathway. Recently, however, specific defects in complex I, complex III, and complex IV have been identified in patients with severe exercise intolerance with or without myoglobinuria. All patients were sporadic cases and all harbored mutations in protein-coding genes of muscle mtDNA, suggesting that these were somatic mutations not affecting the germ-line. Another respiratory chain defect, primary coenzyme Q10 (CoQ10) deficiency, also causes exercise intolerance and recurrent myoglobinuria, usually in conjunction with brain symptoms, such as seizures or cerebellar ataxia. Primary CoQ10 deficiency is probably due to mutations in nuclear gene(s) encoding enzymes involved in CoQ10 biosynthesis.

    Topics: Adolescent; Adult; Coenzymes; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Exercise; Exercise Tolerance; Fatty Acids; Female; Glycogen; Humans; Intracellular Membranes; Male; Metabolism, Inborn Errors; Middle Aged; Mitochondria, Muscle; Mitochondrial Myopathies; Muscle Cramp; Muscles; Myoglobinuria; NADH, NADPH Oxidoreductases; Ubiquinone

1999

Other Studies

1 other study(ies) available for ubiquinone and Muscle-Cramp

ArticleYear
Nonprescription Coenzyme Q10 shown to lower blood pressure. Over-the-counter supplements may also relieve statin-related leg pain.
    Heart advisor, 2010, Volume: 13, Issue:11

    Topics: Anticholesteremic Agents; Attitude to Health; Blood Pressure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Cramp; Pain; Ubiquinone; Vitamins

2010