ubiquinone has been researched along with Kwashiorkor* in 2 studies
1 trial(s) available for ubiquinone and Kwashiorkor
Article | Year |
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Hematological activity of coenzyme Q in an anemia of human malnutrition.
Topics: Anemia, Macrocytic; Animals; Child, Preschool; Clinical Trials as Topic; Electron Transport; Erythrocyte Count; Erythropoiesis; Female; Haplorhini; Hematocrit; Hemoglobins; Humans; Infant; Infant Nutrition Disorders; Kwashiorkor; Male; Rabbits; Reticulocytes; Ubiquinone | 1968 |
1 other study(ies) available for ubiquinone and Kwashiorkor
Article | Year |
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Antioxidant vitamins in malnourished Nigerian children.
The antioxidant capacity in malnutrition--as far as it is related to vitamins--was studied by determining the plasma concentrations of the most prominent antioxidant vitamins (retinol, tocopherols, carotenoids, cryptoxanthine, lycopene, and ubiquinone-10) in marasmic (M; n = 15), severe marasmic (SM; n = 8), kwashiorkor (KW; n = 12), and normally nourished (CO; n = 18) children in Nigeria. Retinol was found to be reduced in severe marasmic children when compared to local controls (medians and interquartile ranges; SM: 155 micrograms/l, 117-178 micrograms/l; CO: 281 micrograms/l 209-413 micrograms/l; p < 0.005). A strong correlation between plasma retinol and retinol binding protein could be found in all groups (SM: r = 0.79; M: r = 0.93; KW: r = 0.80; CO: r = 0.70). The tocopherol/lipid-ratio was lowered in kwashiorkor (median 0.48 mg/g, interquartile range 0.41-0.66 mg/g). A sufficient tocopherol status was only found in one child with kwashiorkor. alpha-Carotene, beta-carotene, cryptoxanthine and lycopene were below the detection limits in most of the malnourished children. Plasma ubiquinone-10 was significantly higher in kwashiorkor (median 1.05 micrograms/ml, interquartile range 0.88-1.17 micrograms/ml) than in all other groups (CO: 0.71 micrograms/ml, 0.55-0.99 micrograms/ml: M: 0.72 micrograms/ml, 0.65-0.83 micrograms/ml; SM: 0.89 micrograms/ml, 0.61-0.83 micrograms/ml). It is concluded that a depletion of antioxidant vitamins is present in malnourished Nigerian children, especially pronounced in the kwashiorkor syndrome. The mechanisms leading to elevated plasma ubiquinone-10 in kwashiorkor require further studies. Topics: Antioxidants; beta Carotene; Carotenoids; Cryptoxanthins; Female; Humans; Infant; Kwashiorkor; Lycopene; Male; Nigeria; Protein-Energy Malnutrition; Ubiquinone; Vitamin A; Vitamin E; Vitamins; Xanthophylls | 1994 |