ubiquinone and Gingival-Diseases

ubiquinone has been researched along with Gingival-Diseases* in 2 studies

Trials

1 trial(s) available for ubiquinone and Gingival-Diseases

ArticleYear
Evidence for enhanced treatment of periodontal disease by therapy with coenzyme Q.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1973, Volume: 43, Issue:4

    Topics: Adult; Aged; Avitaminosis; Clinical Trials as Topic; Gingival Diseases; Gingival Hyperplasia; Gingivitis; Humans; Male; Middle Aged; Oral Hemorrhage; Pain; Periodontal Diseases; Periodontitis; Placebos; Pruritus; Tooth Mobility; Ubiquinone

1973

Other Studies

1 other study(ies) available for ubiquinone and Gingival-Diseases

ArticleYear
Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:4

    The specific activities of both the succinate dehydrogenase-coenzyme Q(10) reductase and the DPNH-cytochrome c reductase [NADH:(acceptor)oxidoreductase, EC 1.6.99.3] were determined in mitochondria from 40 diseased gingival biopsies from patients with periodontal disease and from 24 control biopsies from nondiseased areas (clinically evaluated) of gingival tissues from the same mouths of the patients from whom the diseased gingival tissues were taken. The control tissue was taken during normal surgical procedures, such as for gingival recontouring and tuberosity removal. The diseased gingival biopsies showed a mean specific activity for the succinate dehydrogenase-coenzyme Q(10) reductase which was higher (P < 0.02) than that of the control biopsies, and which increased (P < 0.01) when the assays utilized exogenous coenzyme Q(3), and corresponded to an average deficiency of coenzyme Q(10)-enzyme activity of 35%. About 60% of the 40 diseased gingival tissues showed a deficiency of coenzyme Q(10) at its site in this succinate-coenzyme Q(10) enzyme. Of the 24 control tissues, 20% showed deficiencies of coenzyme Q(10). As a group, the control tissues showed no deficiency of coenzyme Q(10). No deficiency of coenzyme Q(10) at its site in DPNH-cytochrome c reductase was observed for either the control or diseased gingival tissues, as groups or individually.

    Topics: Adolescent; Adult; Cytochrome c Group; Cytochrome Reductases; Female; Gingiva; Gingival Diseases; Humans; Male; Middle Aged; Mitochondria; NADH, NADPH Oxidoreductases; Succinate Dehydrogenase; Ubiquinone

1974