ubiquinone has been researched along with Diabetic-Ketoacidosis* in 2 studies
2 other study(ies) available for ubiquinone and Diabetic-Ketoacidosis
Article | Year |
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Myocardial dysfunction in mitochondrial diabetes treated with Coenzyme Q10.
Maternally-inherited diabetes and deafness (MIDD) has been related to an A to G transition in the mitochondrial tRNA Leu (UUR) gene at the base pair 3243. Although some previous articles have reported that this mutation may be a cause of cardiomyopathy in diabetes, the degree of cardiac involvement and a specific treatment has not been established. Here, we reported a case of a patient with MIDD who developed congestive heart failure and the therapeutic usefulness of Coenzyme Q10 (CoQ10). In our patient, after the introduction of Coenzyme Q10 150 mg/day, there was a gradual improvement on left ventricular function evaluated by echocardiography. The fractional shortening (FS) and ejection fraction (EF) increased from 26 to 34% and from 49 to 64%, respectively. No side effects were noted. Three months after CoQ10 discontinuation, the parameters of systolic function evaluated by echocardiography decreased, suggesting that CoQ10 had a beneficial effect. Identification of diabetes and cardiomyopathy due to mitochondrial gene mutation may have therapeutic implications and Coenzyme Q10 is a possible adjunctive treatment in such patients. Topics: Adult; Antioxidants; Coenzymes; Diabetic Ketoacidosis; DNA, Mitochondrial; Female; Heart; Heart Function Tests; Humans; Insulin; Mutation, Missense; RNA, Transfer, Leu; Ubiquinone; Wolff-Parkinson-White Syndrome | 2006 |
Effect of ubiquinone 35 on hypercitricemia.
Topics: Animals; Blood Glucose; Citrates; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Periodontal Diseases; Rats; Ubiquinone | 1968 |