Compounds > ubenimex
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ubenimex and Pregnancy

ubenimex has been researched along with Pregnancy in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's12 (66.67)18.2507
2000's3 (16.67)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casares-Crespo, L; Castellini, C; Fernández-Serrano, P; Mocé, E; Stabile, AM; Vicente, JS; Viudes-de-Castro, MP1
Ino, K; Itakura, A; Ito, M; Kajiyama, H; Kikkawa, F; Mizutani, S; Nomura, S; Tsujimoto, M; Watanabe, Y1
Itakura, A; Kuno, N; Mizutani, S; Murata, Y; Nakashima, Y; Ohno, Y; Takeuchi, M1
Fujiwara, H; Goto, Y; Hattori, A; Maeda, M; Maruyama, M; Tsujimoto, M; Ueda, M1
el Maradny, E; Halim, A; Kanayama, N; Maehara, K; Sumimoto, K; Terao, T1
Ginther, OJ; Lunn, DP; Vagnoni, KE1
Goto, K; Itakura, A; Kikkawa, F; Kurauchi, O; Mizuno, M; Mizutani, S; Nakazato, H; Safwat, MA; Tomoda, Y; Tsujimoto, M1
Goto, K; Itakura, A; Kikkawa, F; Kurauchi, O; Mizuno, K; Mizutani, S; Nakazato, H; Naruki, M; Tomoda, Y; Tsujimoto, M1
Fujiwara, H; Goto, Y; Maeda, M; Mori, T; Nakamura, K; Nakayama, T; Suginami, H; Tachibana, T; Ueda, M1
Fujita, J; Fujiwara, H; Higuchi, T; Honda, T; Maeda, M; Mori, T; Nakamura, K; Nakayama, T; Suginami, H; Tachibana, T; Yamada, S1
Mizutani, S; Tomoda, Y; Yokosawa, H1
Asada, E; Goto, S; Ino, K; Ishizuka, T; Mano, H; Tomoda, Y; Yamada, A1
Asada, E; Furuhashi, Y; Goto, S; Ino, K; Kosaki, A; Misawa, T; Mizutani, S; Nomura, S; Tomoda, Y1
Ishiura, S; Nojima, M; Okuyama, T; Sugita, H; Tsukahara, T; Yanagida, M1
Ho, PC; Lawton, JW; Ma, HK; Wong, LC1
Kasugai, M; Kurauchi, O; Mizutani, S; Narita, O; Nomura, S; Tomoda, Y1
Furuhashi, M; Kasugai, M; Kurauchi, O; Mizutani, S; Tomoda, Y1
Furuhashi, M; Imaizumi, H; Ito, Y; Kurauchi, O; Mizutani, S; Narita, O; Taira, H; Tomoda, Y1

Trials

1 trial(s) available for ubenimex and Pregnancy

ArticleYear
A controlled trial of bestatin in hydatidiform mole.
    Cancer immunology, immunotherapy : CII, 1990, Volume: 31, Issue:3

    Topics: Adjuvants, Immunologic; Adult; B-Lymphocytes; Female; Humans; Hydatidiform Mole; Killer Cells, Natural; Leucine; Leukocyte Count; Pregnancy; Prospective Studies; Randomized Controlled Trials as Topic; T-Lymphocytes

1990

Other Studies

17 other study(ies) available for ubenimex and Pregnancy

ArticleYear
Insemination extender supplementation with bestatin and EDTA has no effect on rabbit reproductive performance.
    Theriogenology, 2018, Jan-01, Volume: 105

    Topics: Animals; Edetic Acid; Female; Fertility; Insemination, Artificial; Leucine; Male; Pregnancy; Rabbits; Semen; Semen Analysis; Semen Preservation; Sperm Motility; Spermatozoa

2018
Possible involvement of placental peptidases that degrade gonadotropin-releasing hormone (GnRH) in the dynamic pattern of placental hCG secretion via GnRH degradation.
    Placenta, 2002, Volume: 23, Issue:6

    Topics: Adult; Antibodies, Blocking; Chorionic Villi; Chromatography, High Pressure Liquid; Edetic Acid; Female; Glycopeptides; Gonadotropin-Releasing Hormone; Humans; Intracellular Membranes; Labor, Obstetric; Leucine; Leucyl Aminopeptidase; Neprilysin; Organ Culture Techniques; Phenanthrolines; Pregnancy; Pregnancy Trimester, First; Protease Inhibitors; Thiorphan

2002
Bestatin results in pathophysiological changes similar to preeclampsia in rats via induction of placental apoptosis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:6

    Topics: Animals; Apoptosis; Birth Weight; Blood Pressure; Disease Models, Animal; Female; Gestational Age; In Situ Nick-End Labeling; Leucine; Organ Size; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Rats; Rats, Wistar

2003
Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases.
    The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28

    Topics: Amino Acid Motifs; Animals; Baculoviridae; CD13 Antigens; DNA, Complementary; Female; Gene Expression; Humans; Leucine; Metalloproteases; Placentation; Pregnancy; Protease Inhibitors; Recombinant Proteins; Substrate Specificity; Trophoblasts

2007
Regulatory effect of aminopeptidase inhibitor (bestatin) on the cervix during induction of ripening by interleukin-8.
    Journal of leukocyte biology, 1995, Volume: 57, Issue:6

    Topics: Animals; Cervix Uteri; Collagen; Collagenases; Female; Interleukin-8; Leucine; Leukocyte Elastase; Neutrophils; Pancreatic Elastase; Pregnancy; Rabbits

1995
Metalloproteinase activity has a role in equine chorionic girdle cell invasion.
    Biology of reproduction, 1995, Volume: 53, Issue:4

    Topics: Animals; Aprotinin; Cell Movement; Cells, Cultured; Collagen; Drug Combinations; Embryo Implantation; Extracellular Matrix; Female; Horses; Laminin; Leucine; Metalloendopeptidases; Phenanthrolines; Pregnancy; Protease Inhibitors; Proteoglycans; Trophoblasts

1995
Initiating and responsible enzyme of arginine vasopressin degradation in human placenta and pregnancy serum.
    Regulatory peptides, 1995, Nov-10, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Arginine Vasopressin; Cell Fractionation; Cystinyl Aminopeptidase; Cytoplasm; Dipeptides; Edetic Acid; Female; Glycopeptides; Humans; Hydrolysis; Leucine; Lysosomes; Mercaptoethanol; Microsomes; Molecular Sequence Data; Placenta; Pregnancy; Protease Inhibitors

1995
Oxytocin is hydrolyzed by an enzyme in human placenta that is identical to the oxytocinase of pregnancy serum.
    Peptides, 1996, Volume: 17, Issue:2

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cystinyl Aminopeptidase; Edetic Acid; Female; Humans; Hydrolysis; Leucine; Leucyl Aminopeptidase; Lysosomes; Microsomes; Molecular Sequence Data; Oxytocin; Placenta; Pregnancy

1996
An aminopeptidase inhibitor, bestatin, enhances gonadotrophin-stimulated ovulation in mice.
    Human reproduction (Oxford, England), 1996, Volume: 11, Issue:9

    Topics: Aminopeptidases; Animals; Antibodies, Monoclonal; Cell Count; Chorionic Gonadotropin; Drug Synergism; Female; Fluorescent Antibody Technique, Indirect; Gonadotropins, Equine; Histocytochemistry; Leucine; Mice; Mice, Inbred ICR; Oocytes; Ovary; Ovulation; Pregnancy; Staining and Labeling

1996
Bestatin, an aminopeptidase inhibitor, promotes follicular growth and ovulation suppressed by stress in mice.
    Endocrine journal, 1998, Volume: 45, Issue:4

    Topics: Aminopeptidases; Animals; Aromatase; Blotting, Northern; Estradiol; Female; Leucine; Mice; Ovarian Follicle; Ovulation; Pregnancy; Protease Inhibitors; Radioimmunoassay; RNA, Messenger; Starvation; Stress, Physiological

1998
Degradation of oxytocin by the human placenta: effect of selective inhibitors.
    Acta endocrinologica, 1992, Volume: 127, Issue:1

    Topics: Amino Acids; Aminopeptidases; Anti-Bacterial Agents; CD13 Antigens; Chromatography, High Pressure Liquid; Cystinyl Aminopeptidase; Female; Glycopeptides; Humans; Leucine; Leucyl Aminopeptidase; Lysosomes; Microsomes; Oligopeptides; Oxytocin; Peptides; Placenta; Pregnancy; Prolyl Oligopeptidases; Puromycin; Serine Endopeptidases; Subcellular Fractions

1992
Prophylactic effect of bestatin on the onset of invasive mole--clinical and fundamental studies.
    Biotherapy (Dordrecht, Netherlands), 1992, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Leucine; Middle Aged; Pregnancy; Thymidine; Tumor Cells, Cultured

1992
Growth inhibitory effect of bestatin on choriocarcinoma cell lines in vitro.
    Biotherapy (Dordrecht, Netherlands), 1991, Volume: 3, Issue:4

    Topics: Aminopeptidases; Choriocarcinoma; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Leucine; Pregnancy; Stereoisomerism; Structure-Activity Relationship; Succinate Dehydrogenase; Tumor Cells, Cultured; Uterine Neoplasms

1991
Aminopeptidase A in human placenta and pregnant serum.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Feb-15, Volume: 196, Issue:2-3

    Topics: Aminopeptidases; Anti-Bacterial Agents; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Cystinyl Aminopeptidase; Female; Glutamyl Aminopeptidase; Guanidines; Humans; Leucine; Leucyl Aminopeptidase; Oligopeptides; Peptides; Phenanthrolines; Placenta; Pregnancy; Puromycin

1991
Effects of low molecular weight peptides and divalent cations on degradation and binding of angiotensin II.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:8

    Topics: Adult; Aminopeptidases; Angiotensin II; Anti-Bacterial Agents; Cations, Divalent; Cobalt; Female; Humans; In Vitro Techniques; Iodine Radioisotopes; Leucine; Molecular Weight; Oligopeptides; Peptides; Placenta; Pregnancy

1990
Effects of bestatin on intrauterine growth of rat fetuses.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:7

    Topics: Alkaline Phosphatase; Aminopeptidases; Animals; Brain; CD13 Antigens; Embryonic and Fetal Development; Female; Fetal Growth Retardation; Leucine; Liver; Microsomes; Placenta; Pregnancy; Rats; Rats, Inbred Strains

1989
Effect of microsomal leucine aminopeptidase from human placenta (microsomal P-LAP) on pressor response to infused angiotensin II (A-II) in rat.
    Experimental and clinical endocrinology, 1987, Volume: 90, Issue:2

    Topics: Angiotensin II; Animals; Blood Pressure; Female; Humans; Indomethacin; Leucine; Leucyl Aminopeptidase; Male; Microsomes; Placenta; Pregnancy; Rats; Rats, Inbred Strains

1987