Page last updated: 2024-08-25

ubenimex and Malaria, Falciparum

ubenimex has been researched along with Malaria, Falciparum in 6 studies

*Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Andrews, KT; Gardiner, DL; McCarthy, J; Melville, L; Skinner-Adams, TS1
Dalal, S; Klemba, M1
Ariefta, NR; Hatano, M; Igarashi, M; Ikeda, N; Isshiki, K; Matoba, K; Nihei, CI; Nishikawa, Y; Pagmadulam, B1
Buckle, AM; Kass, I; Lei, X; McGowan, S; Porebski, BT; Riley, BT; Yang, W1
Bell, A; Dalton, JP; Gavigan, CS1
Miller, ME; Nelson, SW; Parrott, EE; Singh, R1

Other Studies

6 other study(ies) available for ubenimex and Malaria, Falciparum

ArticleYear
Synergistic interactions of the antiretroviral protease inhibitors saquinavir and ritonavir with chloroquine and mefloquine against Plasmodium falciparum in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Animals; Antimalarials; Chloroquine; Drug Synergism; HIV Protease Inhibitors; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Ritonavir; Saquinavir

2007
Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum.
    The Journal of biological chemistry, 2007, Dec-07, Volume: 282, Issue:49

    Topics: Amino Acids; Aminopeptidases; Animals; Cell Proliferation; Cytoplasm; Hemoglobins; Humans; Hydrolysis; Leucine; Malaria, Falciparum; Plasmodium falciparum; Protease Inhibitors; Protozoan Proteins; Vacuoles

2007
Antiplasmodial Activity Evaluation of a Bestatin-Related Aminopeptidase Inhibitor, Phebestin.
    Antimicrobial agents and chemotherapy, 2023, 07-18, Volume: 67, Issue:7

    Topics: Aminopeptidases; Animals; Antimalarials; Chloroquine; Humans; Malaria; Malaria, Falciparum; Mice; Parasitemia; Plasmodium berghei; Plasmodium falciparum

2023
Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.
    ChemMedChem, 2018, 12-06, Volume: 13, Issue:23

    Topics: Aminopeptidases; Antimalarials; Catalytic Domain; Drug Discovery; Enzyme Inhibitors; Humans; Leucine; Malaria, Falciparum; Molecular Docking Simulation; Molecular Dynamics Simulation; Plasmodium falciparum; Protein Binding

2018
The role of aminopeptidases in haemoglobin degradation in Plasmodium falciparum-infected erythrocytes.
    Molecular and biochemical parasitology, 2001, Sep-28, Volume: 117, Issue:1

    Topics: Aminopeptidases; Animals; Erythrocytes; Hemoglobins; Humans; Leucine; Malaria, Falciparum; Plasmodium falciparum

2001
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucleases; Humans; Kinetics; Malaria, Falciparum; Mitochondria; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Peptide Library; Plasmodium falciparum; Protozoan Proteins; Spectrometry, Fluorescence

2014