ubenimex has been researched along with Invasiveness, Neoplasm in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, G; Fang, C; Guo, L; Guo, S; Song, W; Wang, S; Wang, X; Wei, L; Yang, H; Zhang, H; Zhang, L; Zhao, X; Zhao, Y | 1 |
| Gong, JH; Li, Y; Zhen, YS; Zheng, YB | 1 |
| Gao, B; Liang, W; Qian, Y; Weng, D; Xie, M; Xu, G | 1 |
| Liu, S; Liu, X; Liu, Z; Niu, Z; Sun, L; Wang, H; Xie, F | 1 |
| Deng, Y; Fang, C; Mao, S; Qu, M; Shi, L; Wang, X; Xu, L; Xu, W | 1 |
| Bi, D; Cui, M; Han, L; Jia, Y; Liu, S; Liu, Z; Niu, Z; Wang, X; Zhang, Y | 1 |
| Gullbo, J; Larsson, R; Nygren, P; Wickström, M | 1 |
| Koizumi, K; Minami, T; Saiki, I; Saitoh, Y; Sakurai, H; Sekine, K | 1 |
| Fujioka, S; Hiwada, K; Kohno, N | 1 |
| Fujii, H; Nakajima, M; Ueda, M; Ueki, M; Yoshizawa, K | 1 |
| Dodo, K; Fujimoto, Y; Hashimoto, Y; Kato, F; Kato, M; Koiso, Y; Komoda, M; Miyachi, H; Miyata, K; Shimazawa, R; Shirai, R; Takayama, H; Yamasaki, R | 1 |
| Fujimoto, Y; Hashimoto, Y; Kadoya, S; Kagechika, H; Kato, F; Kato, M; Koiso, Y; Komoda, M; Miyata, K; Takayama, H | 1 |
| Hioki, T; Hirano, K; Ishii, K; Sugimura, Y; Tatematsu, M; Usui, S; Yamamoto, H; Yoshida, S | 1 |
| Abe, F; Azuma, I; Fujii, H; Kojima, Y; Saiki, I; Yoneda, J | 1 |
| Hattori, T; Hirai, T; Niimoto, M; Nishiyama, M; Saeki, T; Toi, M; Yanagawa, E | 1 |
| Abe, F; Azuma, I; Fujii, H; Murata, J; Saiki, I; Watanabe, K | 1 |
2 review(s) available for ubenimex and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Aminopeptidase N (CD13) as a target for cancer chemotherapy.
Topics: CD13 Antigens; Cell Proliferation; Clinical Trials as Topic; Glycine; Humans; Hydroxamic Acids; Leucine; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Prognosis; Protease Inhibitors | 2011 |
Novel small molecule nonpeptide aminopeptidase n inhibitors with a cyclic imide skeleton.
Topics: Antineoplastic Agents; CD13 Antigens; Leucine; Neoplasm Invasiveness; Phthalimides; Protease Inhibitors; Structure-Activity Relationship | 1999 |
1 trial(s) available for ubenimex and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Prospective randomized controlled study on bestatin in resectable gastric cancer--third report.
Topics: Adjuvants, Immunologic; Aminopeptidases; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Gastrectomy; Humans; Leucine; Lymphocyte Activation; Mitomycin; Mitomycins; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Prospective Studies; Randomized Controlled Trials as Topic; Stomach Neoplasms; Survival Rate; Tegafur; Tuberculin Test | 1990 |
13 other study(ies) available for ubenimex and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products.
Topics: Antineoplastic Agents; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Female; Humans; K562 Cells; Leucine; Leucyl Aminopeptidase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Molecular Docking Simulation; Neoplasm Invasiveness; Neoplasm Metastasis | 2020 |
[Inhibition of tumor cell invasion and induction of apoptosis by ubenimex].
Topics: Antibiotics, Antineoplastic; Apoptosis; CD13 Antigens; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Fibrosarcoma; Humans; Leucine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness | 2012 |
Possible contribution of aminopeptidase N (APN/CD13) to migration and invasion of human osteosarcoma cell lines.
Topics: CD13 Antigens; Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Neoplastic; Humans; Leucine; MAP Kinase Signaling System; Neoplasm Invasiveness; Osteosarcoma; RNA, Messenger; Signal Transduction | 2014 |
Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma: the effect is autophagy-associated.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Aminopeptidases; Antibiotics, Antineoplastic; Autophagy; Carcinoma, Renal Cell; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Leucine; Middle Aged; Neoplasm Invasiveness; Sirolimus; Wound Healing; Young Adult | 2015 |
Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9.
Topics: Carrier Proteins; Cell Line, Tumor; Cell Movement; Down-Regulation; Female; Gene Knockdown Techniques; HSP27 Heat-Shock Proteins; Humans; Leucine; Leucyl Aminopeptidase; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microfilament Proteins; Neoplasm Invasiveness; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protease Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2015 |
Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
Topics: Animals; Antineoplastic Agents; Autophagy; CD13 Antigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Leucine; Male; Mice; Mice, Nude; Neoplasm Invasiveness; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2016 |
A derivative of aminopeptidase inhibitor (BE15) has a dual inhibitory effect of invasion and motility on tumor and endothelial cells.
Topics: Aminopeptidases; Animals; Antibiotics, Antineoplastic; Capillaries; Cell Line; Cell Movement; Cell Survival; Endothelial Cells; Extracellular Matrix; Humans; Leucine; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Neoplasms; Protease Inhibitors; Wound Healing | 2006 |
Ubenimex activates the E-cadherin-mediated adhesion of a breast cancer cell line YMB-S.
Topics: Antibiotics, Antineoplastic; Antibodies; Breast Neoplasms; Cadherins; Carcinoma, Ductal, Breast; Cell Adhesion; Cell Aggregation; Cell Division; Collagen; Culture Media; Drug Combinations; Humans; Immunohistochemistry; Laminin; Leucine; Leukotriene B4; Neoplasm Invasiveness; Proteoglycans; Tumor Cells, Cultured | 1995 |
Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A.
Topics: Aminopeptidases; Antibiotics, Antineoplastic; Cell Division; Cell Movement; Female; Gelatinases; Humans; Leucine; Matrix Metalloproteinase 2; Metalloendopeptidases; Neoplasm Invasiveness; Protease Inhibitors; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1997 |
Potent homophthalimide-type inhibitors of B16F10/L5 mouse melanoma cell invasion.
Topics: Aminopeptidases; Animals; Antineoplastic Agents; Enzyme Inhibitors; Humans; Hydroxamic Acids; Isoquinolines; Leucine; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Tumor Cells, Cultured | 1999 |
Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion.
Topics: Amino Acid Sequence; CD13 Antigens; Copper; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Enzyme Inhibitors; Epithelium; Humans; Immunohistochemistry; Leucine; Male; Neoplasm Invasiveness; Peptide Fragments; Phenanthrolines; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Zinc | 2001 |
Inhibition of tumor invasion and extracellular matrix degradation by ubenimex (bestatin).
Topics: Adult; Aminopeptidases; Antibiotics, Antineoplastic; Carcinoma, Renal Cell; Cell Adhesion; Cell Movement; Collagen; Culture Media; Enzyme Inhibitors; Humans; Kidney Neoplasms; Leucine; Male; Neoplasm Invasiveness | 1992 |
Inhibition of tumor cell invasion by ubenimex (bestatin) in vitro.
Topics: Aminopeptidases; Animals; Antibiotics, Antineoplastic; Collagen; Drug Combinations; Fibronectins; Laminin; Leucine; Mice; Neoplasm Invasiveness; Proteoglycans; Tumor Cells, Cultured | 1989 |